keyword
https://read.qxmd.com/read/38483230/fibrotic-like-pulmonary-radiographic-patterns-in-covid-19-chronic-critical-illness-extraordinary-association-between-obesity-and-interleukin-6-levels
#21
JOURNAL ARTICLE
Li-Juan Zou, Hang Ruan, Yong-Sheng Li
No abstract text is available yet for this article.
April 1, 2024: Critical Care Medicine
https://read.qxmd.com/read/38480876/sulfamethoxazole-induced-crystal-nephropathy-characterization-and-prognosis-in-a-case-series
#22
JOURNAL ARTICLE
Ruben Azencot, Camille Saint-Jacques, Jean-Philippe Haymann, Vincent Frochot, Michel Daudon, Emmanuel Letavernier
Cotrimoxazole (Trimethoprim/Sulfamethoxazole-SMX) is frequently used in critically ill and immunocompromised patients. SMX is converted to N-acetyl-sulfamethoxazole (NASM) and excreted by the kidneys. NASM may form crystals in urine, especially in acid urine, that may induce a crystalline nephropathy. However, the imputability of crystals in acute kidney injury (AKI) has not been proven. We aimed to assess whether NASM crystals may promote AKI and to investigate risk factors associated with NASM crystalline nephropathy...
March 13, 2024: Scientific Reports
https://read.qxmd.com/read/38479299/health-related-quality-of-life-physical-function-and-cognitive-performance-in-mechanically-ventilated-covid-19-patients-a-long-term-follow-up-study
#23
JOURNAL ARTICLE
Luca Carenzo, Leonardo Zini, Cesare Mercalli, Niccolò Stomeo, Angelo Milani, Katia Amato, Roberto Gatti, Elena Costantini, Romina Aceto, Alessandro Protti, Maurizio Cecconi
BACKGROUND: Survivors of severe COVID-19 related respiratory failure may experience durable functional impairments. We aimed at investigating health-related quality of life (HR-QoL), physical functioning, fatigue, and cognitive outcomes in COVID-19 patients who received invasive mechanical ventilation (IMV). METHODS: Case-series, prospective, observational cohort study at 18 months from hospital discharge. Patients referring to the Intensive Care Unit (ICU) of Humanitas Research Hospital (Milan, Italy) were recruited if they needed IMV due to COVID-19 related respiratory failure...
March 12, 2024: Journal of Critical Care
https://read.qxmd.com/read/38478530/how-do-household-living-conditions-and-gender-related-decision-making-influence-child-stunting-in-rwanda-a-population-based-study
#24
JOURNAL ARTICLE
Jean Nepo Utumatwishima, Ingrid Mogren, Aline Umubyeyi, Ali Mansourian, Gunilla Krantz
Child stunting (chronic undernutrition) is a major public health concern in low- and middle-income countries. In Rwanda, an estimated 33% of children are affected. This study investigated the household living conditions and the impact of gender-related decision-making on child stunting. The findings contribute to ongoing discussion on this critical public health issue. In December 2021, a population-based cross-sectional study was conducted in Rwanda's Northern Province; 601 women with children aged 1-36 months were included...
2024: PloS One
https://read.qxmd.com/read/38476066/clinical-characteristics-and-outcomes-of-obstetric-patients-transferred-directly-to-intensive-care-units
#25
JOURNAL ARTICLE
Saad Pirzada, Kimberly Boswell, Jerry Yang, Samantha Asuncion, Fernando Albelo, Amanda Tuchler, Lauren Becker, Allison Lankford, Emad Elsamadicy, Quincy K Tran
BACKGROUND: Medical complications in peripartum patients are uncommon. Often, these patients are transferred to tertiary care centers, but their conditions and outcomes are not well understood. Our study examined peripartum patients transferred to an intensive care unit (ICU) at an academic quaternary center. METHODS: We reviewed charts of adult, non-trauma, interhospital transfer (IHT) peripartum patients sent to an academic quaternary ICU between January 2017 and December 2021...
February 2024: Acute and critical care
https://read.qxmd.com/read/38472197/perceptions-of-critically-ill-individuals-with-acute-and-chronic-spinal-cord-injury-requiring-a-tracheostomy-tube
#26
JOURNAL ARTICLE
Christina Weckwerth, Christian Waydhas, Uwe Hamsen, Oliver Cruciger, Aileen Spieckermann, Thomas Armin Schildhauer, Mirko Aach, Robert Gaschler, Christopher Ull
STUDY DESIGN: Observational study. OBJECTIVES: To evaluate the perceptions of patients requiring a tracheostomy tube and to identify possible different perceptions in critically ill patients with tracheostomy tubes who have acute (ASCI) or chronic spinal cord injuries (CSCI). SETTING: Medical and surgical intensive care units (ICU) and intermediate care unit of the BG University Hospital Bergmannsheil Bochum, Germany. METHODS: Patients who met the inclusion criteria completed a 25-item questionnaire on two consecutive days regarding their experiences and perceptions in breathing, coughing, pain, speaking, swallowing, and comfort of the tracheostomy tube...
March 13, 2024: Spinal Cord Series and Cases
https://read.qxmd.com/read/38471985/application-of-a-multiplex-molecular-pneumonia-panel-and-real-world-impact-on-antimicrobial-stewardship-among-patients-with-hospital-acquired-and-ventilator-associated-pneumonia-in-intensive-care-units
#27
JOURNAL ARTICLE
Chieh-Lung Chen, How-Yang Tseng, Wei-Cheng Chen, Shinn-Jye Liang, Chih-Yen Tu, Yu-Chao Lin, Po-Ren Hsueh
BACKGROUND: The optimal timing for applying the BioFire FilmArray Pneumonia Panel (FAPP) in intensive care unit (ICU) patients with hospital-acquired pneumonia (HAP) or ventilator-associated pneumonia (VAP) remains undefined, and there are limited data on its impact on antimicrobial stewardship. METHODS: This retrospective study was conducted at a referral hospital in Taiwan from November 2019 to October 2022. Adult ICU patients with HAP/VAP who underwent FAPP testing were enrolled...
March 6, 2024: Journal of Microbiology Immunology and Infection
https://read.qxmd.com/read/38469112/outcomes-of-critically-ill-patients-with-liver-failure-who-require-mechanical-ventilation-a-retrospective-single-center-study
#28
JOURNAL ARTICLE
Atsuyoshi Mita, Sari Shimizu, Takashi Ichiyama, Takateru Yamamoto, Akinori Yamaguchi, Kosuke Sonoda, Kotaro Mori, Tomokatsu Yamada, Hiroyuki Nakamura, Hiroshi Imamura
BACKGROUND AND AIMS: Critically ill patients with liver failure have high mortality. Besides the management of organ-specific complications, liver transplantation constitutes a definitive treatment. However, clinicians may hesitate to introduce mechanical ventilation for patients on liver transplantation waitlists because of poor prognosis. This study investigated the outcomes of intensive care and ventilation support therapy effects in patients with liver failure. METHODS: This single-center study retrospectively enrolled 32 consecutive patients with liver failure who were admitted to the intensive care unit from January 2014 to December 2020...
March 2024: Health Science Reports
https://read.qxmd.com/read/38464562/prognostic-value-of-leukocyte-based-risk-model-for-acute-kidney-injury-prediction-in-critically-ill-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-patients
#29
JOURNAL ARTICLE
Min Cai, Yue Deng, Tianyang Hu
PURPOSE: Acute kidney injury (AKI) is a common complication of acute exacerbation of chronic obstructive pulmonary disease (AECOPD), and inflammation is the potential link between AKI and AECOPD. However, little is known about the incidence and risk stratification of AKI in critically ill AECOPD patients. In this study, we aimed to establish risk model based on white blood cell (WBC)-related indicators to predict AKI in critically ill AECOPD patients. MATERIAL AND METHODS: For the training cohort, data were taken from the Medical Information Mart for eICU Collaborative Research Database (eICU-CRD) database, and for the validation cohort, data were taken from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database...
2024: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/38462971/natural-compounds-for-oxidative-stress-and-neuroprotection-in-schizophrenia-composition-mechanisms-and-therapeutic-potential
#30
REVIEW
Anam N Khan, Rahul D Jawarkar, Magdi E A Zaki, Aamal A Al Mutairi
OBJECTIVE: An imbalance between the generation of reactive oxygen species (ROS) and the body's antioxidant defense mechanisms is believed to be a critical factor in the development of schizophrenia (SCZ) like neurological illnesses. Understanding the roles of ROS in the development of SCZ and the potential activity of natural antioxidants against SCZ could lead to more effective therapeutic options for the prevention and treatment of the illness. METHODS: SCZ is a mental disorder characterised by progressive impairments in working memory, attention, and executive functioning...
March 11, 2024: Nutritional Neuroscience
https://read.qxmd.com/read/38462074/distribution-of-acute-and-chronic-kidney-disease-across-clinical-phenotypes-for-sepsis
#31
JOURNAL ARTICLE
Luca Molinari, Gaspar Del Rio-Pertuz, Priyanka Priyanka, Ali Smith, Joseph C Maggiore, Jason Kennedy, Hernando Gomez, Christopher W Seymour, John A Kellum
BACKGROUND: Sepsis is the most common cause of Acute Kidney Injury (AKI) in critically ill patients. Four phenotypes (α, β, γ, δ) for sepsis, which have different outcomes and response to treatment, were described using routine clinical data in the electronic health record. RESEARCH QUESTIONS: Do the frequencies of AKI, acute kidney disease (AKD), chronic kidney disease (CKD), and AKI-on-CKD differ by sepsis phenotype? STUDY DESIGN AND METHODS: Secondary analysis of a randomized clinical trial of early resuscitation, including patients with septic shock at 31 sites...
March 8, 2024: Chest
https://read.qxmd.com/read/38451788/determinants-of-pressure-injury-development-in-patients-with-covid-19
#32
JOURNAL ARTICLE
Lee H Kilmer, Ankita Samuel, Grace L Forster, John T Stranix, Jonathan S Black, Christopher A Campbell, Brent R DeGeorge
OBJECTIVE: Pressure injuries (PIs) often develop in critically ill patients due to immobility, and underlying comorbidities that decrease tissue perfusion and wound healing capacity. This study sought to provide epidemiological data on determinants and current managements practices of PI in patients with COVID-19. METHOD: A US national insurance-based database consisting of patients with coronavirus or COVID-19 diagnoses was used for data collection. Patients were filtered by International Classification of Diseases (ICD) codes corresponding to coronavirus or COVID-19 diagnosis between 2019-2020...
March 2, 2024: Journal of Wound Care
https://read.qxmd.com/read/38445974/healthcare-burden-and-resource-utilization-after-pediatric-acute-respiratory-distress-syndrome-a-secondary-analysis-of-the-collaborative-pediatric-critical-care-research-network-acute-respiratory-distress-syndrome-study
#33
JOURNAL ARTICLE
Stefanie G Ames, Aline B Maddux, Lauren Burgunder, Huong Meeks, Erica L Fink, Kathleen L Meert, Matt S Zinter, Peter M Mourani, Joseph A Carcillo, Todd Carpenter, Murray M Pollack, Manvita Mareboina, Daniel A Notterman, Anil Sapru
OBJECTIVES: To describe family healthcare burden and health resource utilization in pediatric survivors of acute respiratory distress syndrome (ARDS) at 3 and 9 months. DESIGN: Secondary analysis of a prospective multisite cohort study. SETTING: Eight academic PICUs in the United States (2019-2020). PATIENTS: Critically ill children with ARDS and follow-up survey data collected at 3 and/or 9 months after the event. INTERVENTIONS: None...
March 6, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38444690/improving-outcomes-in-hepatorenal-syndrome-acute-kidney-injury-with-early-diagnoses-and-implementation-of-approved-treatment-regimens
#34
JOURNAL ARTICLE
Nikolaos T Pyrsopoulos, David Bernstein, Marcelo Kugelmas, Emily J Owen, K Rajender Reddy, Nancy Reau, Sammy Saab, Hani M Wadei
Decompensated cirrhosis, defined by the overt manifestations of liver failure and portal hypertension (eg, ascites, hepatic encephalopathy, variceal bleeding), is the inflection point associated with increased morbidity and mortality in chronic liver disease. Acute kidney injury in the setting of cirrhosis (hepatorenal syndrome-acute kidney injury [HRS-AKI]) is a severe and often fatal complication. The goals of treatment of HRS-AKI are to reverse renal failure and prolong survival in these critically ill patients or perhaps to allow the transplant team to complete the pretransplant evaluation and bridge the patient to transplant...
December 2023: Gastroenterology & Hepatology
https://read.qxmd.com/read/38444550/association-between-serum-anion-gap-and-mortality-in-critically-ill-patients-with-copd-in-icu-data-from-the-mimic-iv-database
#35
JOURNAL ARTICLE
Xiaojing Chen, Qilin Yang, Li Gao, Weinan Chen, Xiaoyu Gao, Yameng Li, Liying Ao, Dejun Sun
BACKGROUND: Serum anion gap (AG) has been proven to be associated with prognosis in critically ill patients. However, few studies have investigated the association between AG and all-cause mortality in critically ill patients with chronic obstructive pulmonary disease (COPD). OBJECTIVE: We hypothesized that the initial AG level would predict the mortality risk in critically ill patients with COPD. METHODS: This retrospective cohort study was based on the Medical Information Mart for Intensive Care (MIMIC) IV database...
2024: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/38434384/clinical-significance-of-inflammatory-markers-for-evaluating-disease-severity-of-mixed-pathogen-bloodstream-infections-of-both-enterococcus-spp-and-candida-spp
#36
JOURNAL ARTICLE
Xin Wang, Ming Li, Yang Yang, Xueyi Shang, Yonggang Wang, Yan Li
OBJECTIVE: In recent decades, there has been a notable increase in the morbidity and mortality rates linked to bacteremia and candidemia. This study aimed to investigate the clinical significance of inflammatory markers in assessing the disease severity in critically ill patients suffering from mixed-bloodstream infections (BSIs) due to Enterococcus spp. and Candida spp. METHODS: In this retrospective research, patients diagnosed with BSIs who were admitted to the intensive care unit (ICU) during the period of January 2019 to December 2022 were analyzed...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38432703/prolonged-mechanical-ventilation-weaning-and-the-role-of-tracheostomy
#37
REVIEW
Louise Rose, Ben Messer
Depending on the definitional criteria used, approximately 5% to 10% of critical adults will require prolonged mechanical ventilation with longer-term outcomes that are worse than those ventilated for a shorter duration. Outcomes are affected by patient characteristics before critical illness and its severity but also by organizational characteristics and care models. Definitive trials of interventions to inform care activities, such as ventilator weaning, upper airway management, rehabilitation, and nutrition specific to the prolonged mechanical ventilation patient population, are lacking...
April 2024: Critical Care Clinics
https://read.qxmd.com/read/38432591/describing-energy-expenditure-in-children-with-a-chronic-disease-a-systematic-review
#38
REVIEW
Bethany Luo, Zoe E Davidson, Katie O'Brien, Evelyn Volders, Jeffrey Lu, Kali Dunlea, Matisse Lazzari, Natassja Billich, Kay Nguo
BACKGROUND: Understanding energy expenditure in children with chronic disease is critical due to the impact on energy homeostasis and growth. OBJECTIVE: This systematic review aimed to describe available literature of resting (REE) and total energy expenditure (TEE) in children with chronic disease measured by gold standard methods of indirect calorimetry (IC) and doubly-labelled water (DLW), respectively. METHODS: A literature search was conducted using OVID Medline, Embase, CINAHL Plus, Cochrane and Scopus until July 2023...
March 1, 2024: Advances in Nutrition
https://read.qxmd.com/read/38431593/the-impact-of-obesity-on-ventilator-associated-pneumonia-a-us-nationwide-study
#39
JOURNAL ARTICLE
Mohamad El Labban, Michella Abi Zeid Daou, Hiba Smaily, Abbas Hammoud, Ghandi Hassan, Syed Khan, Imad Bou Akl
BACKGROUND: Ventilator-associated pneumonia (VAP) is one of the leading causes of mortality in patients with critical care illness. Since obesity is highly prevalent, we wanted to study its impact on the outcomes of patients who develop VAP. METHODS: Using the National Inpatient Sample (NIS) database from 2017 to 2020, we conducted a retrospective study of adult patients with a principal diagnosis of VAP with a secondary diagnosis with or without obesity according to 10th revision of the International Statistical Classification of Diseases (ICD-10) codes...
March 2, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38430507/health-literacy-and-its-association-with-mental-and-spiritual-well-being-among-women-experiencing-homelessness
#40
JOURNAL ARTICLE
Andreas Karlsson Rosenblad, Anna Klarare, Penny Rapaport, Elisabet Mattsson, Sophie Nadia Gaber
Low health literacy (HL) has been linked to low self-rated health, reduced efficacy of behaviour change, and challenges in preventing, treating, or managing health conditions. People experiencing homelessness are at risk of poor HL; however, few studies have investigated HL in relation to mental and spiritual well-being among people experiencing homelessness in general, or women experiencing homelessness specifically. This cross-sectional study of 46 women experiencing homelessness in Stockholm, Sweden, recruited during the period October 2019-December 2020, aimed to examine how HL was associated with mental and spiritual well-being among women experiencing homelessness...
April 1, 2024: Health Promotion International
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