keyword
https://read.qxmd.com/read/38352347/electroanatomical-adaptations-in-the-guinea-pig-heart-from-neonatal-to-adulthood
#21
Kazi T Haq, Kate McLean, Shatha Salameh, Luther Swift, Nikki Gillum Posnack
BACKGROUND: Electroanatomical adaptations during the neonatal to adult phase have not been comprehensively studied in preclinical animal models. To explore the impact of age as a biological variable on cardiac electrophysiology, we employed neonatal and adult guinea pigs, which are a recognized animal model for developmental research. METHODS: Healthy guinea pigs were categorized into three age groups (neonates, n=10; younger adults, n=13; and older adults, n=26)...
January 30, 2024: bioRxiv
https://read.qxmd.com/read/38340118/durability-of-pulmonary-vein-isolation-using-pulsed-field-ablation-results-from-the-multicenter-eu-poria-registry
#22
JOURNAL ARTICLE
Thomas Kueffer, Stefano Bordignon, Kars Neven, Yuri Blaauw, Jim Hansen, Raquel Adelino, Alexandre Ouss, Anna Füting, Laurent Roten, Bart A Mulder, Martin H Ruwald, Roberto Mené, Pepijn van der Voort, Nico Reinsch, Serge Boveda, Elizabeth M Albrecht, Christopher W Schneider, K R Julian Chun, Boris Schmidt, Tobias Reichlin
BACKGROUND: Pulsed-field ablation (PFA) is a novel nonthermal ablation technology with high procedural safety and efficiency for pulmonary vein isolation (PVI). Premarket data showed high PVI durability during mandatory remapping studies. Data on lesion durability in real-world patients with clinically indicated redo procedures are scarce. OBJECTIVES: This study sought to report PVI durability rates in patients undergoing a clinically indicated redo procedure after an index PVI using PFA...
January 5, 2024: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/38333391/identification-of-cavotricuspid-isthmus-voltage-patterns-in-typical-atrial-flutter-ablation
#23
JOURNAL ARTICLE
Francisco Ribes, Ángel Ferrero-de-Loma-Osorio, Juan Miguel Sánchez-Gómez, Lourdes Bondanza, Ángel Martínez-Brotons, Ricardo Ruiz-Granell
BACKGROUND: Electroanatomical mapping is an essential tool in the ablation of typical AFL. OBJECTIVES: To identify the existence of voltage patterns in the CTI voltage maps and their relevance for typical AFL ablation. METHODS: A voltage map of the CTI was made prior to ablation, identifying the areas of maximum voltage and their location along the CTI, allowing classification into patterns according to their distribution. A stepwise ablation approach targeting the areas of maximum voltage was conducted...
February 2024: Journal of Arrhythmia
https://read.qxmd.com/read/38320669/redefining-left-bundle-branch-block-from-high-density-electroanatomical-mapping
#24
JOURNAL ARTICLE
Jun-Hua Zou, Bao-Tong Hua, Xiao-Xia Shao, Chao Wang, Hao Li, Ya-Nan Lu, Xin Tian, Zhi-Xuan Li, Li-Jin Pu, Jing Wang
BACKGROUND: The existing ECG criteria for diagnosing left bundle branch block (LBBB) are insufficient to distinguish between true and false blocks accurately. METHODS: We hypothesized that the notch width of the QRS complex in the lateral leads (I, avL, V5, V6) on the LBBB-like ECG could further confirm the diagnosis of true complete left bundle branch block (t-LBBB). We conducted high-density, three-dimensional electroanatomical mapping in the cardiac chambers of 37 patients scheduled to undergo CRT...
February 4, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38318720/cardiac-pulsed-field-ablation-lesion-durability-assessed-by-polarization-sensitive-optical-coherence-reflectometry
#25
JOURNAL ARTICLE
Maria Terricabras, Raphael P Martins, Rafael Peinado, Pawel Derejko, Lluis Mont, Sabine Ernst, David Herranz, Christophe Bailleul, Atul Verma
BACKGROUND: Pulsed field ablation uses electrical fields to cause nonthermal cell death over several hours. Polarization-sensitive optical coherence reflectometry is an optical imaging technique that can detect changes in the tissue ultrastructure in real time, which occurs when muscular tissue is damaged. The objective of this study was to evaluate the ability of a polarization-sensitive optical coherence reflectometry system to predict the development of chronic lesions based on acute changes in tissue birefringence during pulsed field ablation...
February 6, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38308809/area-weighted-unipolar-voltage-to-predict-heart-failure-outcomes-in-patients-with-ischaemic-cardiomyopathy-and-ventricular-tachycardia
#26
JOURNAL ARTICLE
Robert Rademaker, Yoshi Kimura, Marta de Riva Silva, Hans C Beukers, Sebastiaan R D Piers, Adrianus P Wijnmaalen, Olaf M Dekkers, Katja Zeppenfeld
AIMS: Patients with ischaemic cardiomyopathy (ICM) referred for catheter ablation of ventricular tachycardia (VT) are at risk for end-stage heart failure (HF) due to adverse remodelling. Local unipolar voltages (UV) decrease with loss of viable myocardium. A UV parameter reflecting global viable myocardium may predict prognosis. We evaluate if a newly proposed parameter, area-weighted unipolar voltage (awUV), can predict HF-related outcomes [HFO; HF death/left ventricular (LV) assist device/heart transplant] in ICM...
February 1, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38306471/role-of-electroanatomical-mapping-guided-superior-vena-cava-isolation-in-paroxysmal-atrial-fibrillation-patients-without-provoked-superior-vena-cava-trigger-a-randomized-controlled-study
#27
JOURNAL ARTICLE
Yan Dong, Dongsheng Zhao, Xinguang Chen, Linshen Shi, Qiushi Chen, Haiyan Zhang, Yue Yu, Inam Ullah, Pipin Kojodjojo, Fengxiang Zhang
AIMS: Data about whether empirical superior vena cava isolation (SVCI) improves the success rate of paroxysmal atrial fibrillation (PAF) is conflicting. This study sought to firstly investigate the characteristics of SVC-triggered AF, and secondly investigate the impact of electroanatomical mapping guided SVCI in addition to circumferential pulmonary vein isolation (CPVI) on the outcome of PAF ablation in the absence of provoked SVC triggers. METHODS: A total of 130 patients undergoing PAF ablation underwent electrophysiological studies before ablation...
February 2, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38293729/bipolar-catheter-ablation-with-dedicated-radiofrequency-system-for-highly-refractory-ventricular-arrhythmia-does-the-rate-of-success-depend-on-arrhythmia-origin
#28
JOURNAL ARTICLE
Piotr Gardziejczyk, Roman Piotrowski, Tomasz Kryński, Agnieszka Sikorska, Piotr Kułakowski, Jakub Baran
INTRODUCTION: Despite rapid technological progress, some arrhythmias are still resistant to standard unipolar ablation. These include arrhythmias arising from the base of the heart, cardiac crux, or epicardium. Bipolar radiofrequency ablation (B-RFA) may be useful in some cases, however, data on the efficacy of this approach in various arrhythmia localizations are scarce. The aim of this study was to assess the efficacy of B-RFA in patients with ventricular arrhythmias originating from various locations, occurring refractory to standard unipolar ablation approaches...
January 31, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38286246/characterisation-of-conduction-system-activation-in-the-post-infarct-ventricle-using-ripple-mapping
#29
JOURNAL ARTICLE
George Katritsis, Balrik Kailey, Vishal Luther, Shahnaz Jamil Copley, Michael Koa-Wing, Anu Balasundram, Louisa Malcolme-Lawes, Norman Qureshi, Phang Boon Lim, Fu Siong Ng, Nuno Cortez Diaz, Luis Carpinteiro, Joao de Sousa, Ruairidh Martin, Moloy Das, Stephen Murray, Anthony Chow, Nicholas S Peters, Zachary Whinnett, Nick Wf Linton, Prapa Kanagaratnam
BACKGROUND: Three dimensional (3D) mapping of the ventricular conduction system is challenging. OBJECTIVES: We used Ripple Mapping to distinguish conduction system activation to that of adjacent myocardium, to characterise the conduction system in the post-infarct LV. METHODS: High-density mapping (PentaRay, CARTO) was performed during normal rhythm in patients undergoing VT ablation. Ripple Maps were viewed from the end of the P wave to QRS onset in 1ms increments...
January 27, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38276927/multisize-electrode-field-of-view-validation-by-high-resolution-gadolinium-enhanced-cardiac%C3%A2-magnetic-resonance
#30
JOURNAL ARTICLE
Sharif Omara, Claire A Glashan, Bawer J Tofig, Lore Leenknegt, Hans Dierckx, Alexander V Panfilov, Hans K C Beukers, Michiel H van Waasbergen, Qian Tao, William G Stevenson, Jens C Nielsen, Peter Lukac, Steen B Kristiansen, Rob J van der Geest, Katja Zeppenfeld
BACKGROUND: Voltage mapping to detect ventricular scar is important for guiding catheter ablation, but the field-of-view of unipolar, bipolar, conventional, and microelectrodes as it relates to the extent of viable myocardium (VM) is not well defined. OBJECTIVES: The purpose of this study was to evaluate electroanatomic voltage-mapping (EAVM) with different-size electrodes for identifying VM, validated against high-resolution ex-vivo cardiac magnetic resonance (HR-LGE-CMR)...
January 8, 2024: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/38264119/use-of-an-electroanatomic-mapping-system-with-high-density-multipolar-mapping-catheters-to-guide-transvenous-atrial-pacing-lead-implantation-in-a-fontan-patient
#31
Anthony G Pompa, Benjamin W Hale
No abstract text is available yet for this article.
January 2024: HeartRhythm Case Reports
https://read.qxmd.com/read/38248058/the-fluoroless-future-in-electrophysiology-a-state-of-the-art-review
#32
REVIEW
Alberto Preda, Eleonora Bonvicini, Elena Coradello, Alessio Testoni, Lorenzo Gigli, Matteo Baroni, Marco Carbonaro, Sara Vargiu, Marisa Varrenti, Giulia Colombo, Marco Paolucci, Patrizio Mazzone, Fabrizio Guarracini
Fluoroscopy has always been the cornerstone imaging method of interventional cardiology procedures. However, radiation exposure is linked to an increased risk of malignancies and multiorgan diseases. The medical team is even more exposed to X-rays, and a higher incidence of malignancies was reported in this professional group. In the last years, X-ray exposure has increased rapidly, involving, above all, the medical team and young patients and forcing alternative fluoroless imaging methods. In cardiac electrophysiology (EP) and pacing, the advent of 3D electroanatomic mapping systems with dedicated catheters has allowed real-time, high-density reconstruction of both heart anatomy and electrical activity, significantly reducing the use of fluoroscopy...
January 14, 2024: Diagnostics
https://read.qxmd.com/read/38242530/outcomes-of-focal-pulsed-field-ablation-for-paroxysmal-supraventricular-tachycardia
#33
JOURNAL ARTICLE
Caijie Shen, Xianfeng Du, Jiating Dai, Mingjun Feng, Yibo Yu, Jing Liu, Guohua Fu, Binhao Wang, Yongxing Jiang, He Jin, Huimin Chu
BACKGROUND: Pulsed field ablation (PFA) is primarily used for treatment of atrial fibrillation as it provides better safety and efficacy. However, there are limited data available on the utilization of PFA for paroxysmal supraventricular tachycardia (PSVT). The study sought to describe the outcomes of PSVT ablation with a novel focal contact force (CF)-sensing PFA. METHODS: In this first-in-human pilot study, a focal CF-sensing PFA catheter was used for mapping and ablation navigated with an electroanatomical mapping system (EAMS)...
January 17, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38225174/posterior-wall-ablation-by-pulsed-field-ablation-procedural-safety-efficacy-and-findings-on-redo-procedures
#34
JOURNAL ARTICLE
Thomas Kueffer, Hildegard Tanner, Antonio Madaffari, Jens Seiler, Andreas Haeberlin, Jens Maurhofer, Fabian Noti, Claudia Herrera, Gregor Thalmann, Nikola A Kozhuharov, Tobias Reichlin, Laurent Roten
BACKGROUND: The left atrial posterior wall is a potential ablation target in patients with recurrent atrial fibrillation despite durable pulmonary vein isolation or in patients with roof-dependent atrial tachycardia (AT). Pulsed-field ablation (PFA) offers efficient and safe posterior wall ablation (PWA), but available data is scarce. METHODS: Consecutive patients undergoing PWA using PFA were included. PWA was performed using a pentaspline PFA catheter and verified by 3D-electroanatomic mapping...
January 16, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38204826/a-perfect-storm-of-ventricular-fibrillation-infarct-posterior-fascicle-and-the-moderator-band
#35
Michael Ahlers, Douglas Darden, Kurt Hoffmayer, Gregory K Feld, David E Krummen, Gordon Ho
No abstract text is available yet for this article.
December 2023: HeartRhythm Case Reports
https://read.qxmd.com/read/38198978/successful-high-resolution-three-dimensional-electroanatomical-mapping-and-radiofrequency-catheter-ablation-of-a-posteroseptal-accessory-pathway-in-a-dog-using-carto-3
#36
JOURNAL ARTICLE
A Hellemans, M Duytschaever, G Van Steenkiste, G van Loon, T Bosmans, G Mampaey, P Smets
A one-year-and-seven-month-old, 28 kg, male castrated crossbreed dog was presented for supraventricular tachycardia causing recurrent episodes of anorexia and lethargy. Sotalol (2.2 mg/kg q12 h) reduced the frequency of symptomatic episodes but did not provide full relief. Three-dimensional electroanatomical mapping was performed at the Ghent University Small Animal Teaching hospital using the CARTO 3. Right atrial activation mapping identified the earliest atrial activation right posteroseptal, near the tricuspid annulus...
December 22, 2023: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://read.qxmd.com/read/38193546/cardiac-radiotherapy-transiently-alters-left-ventricular-electrical-properties-and-induces-cardiomyocyte-specific-ventricular-substrate-changes-in-heart-failure
#37
JOURNAL ARTICLE
Felix Mehrhof, Judith Hüttemeister, Radu Tanacli, Matthias Bock, Markus Bögner, Felix Schoenrath, Volkmar Falk, Daniel Zips, Gerhard Hindricks, Jin-Hong Gerds-Li, Felix Hohendanner
BACKGROUND: Ongoing clinical trials investigate the therapeutic value of stereotactic cardiac radioablation (cRA) in heart failure patients with ventricular tachycardia. Animal data indicate an effect on local cardiac conduction properties. However, the exact mechanism of cRA in patients remains elusive. METHODS: High-density 3D electroanatomic mapping in sinus rhythm was performed in a patient with left ventricular assist device and repeated ventricular tachycardia episodes upon several catheter-based endocardial radio-frequency ablation attempts...
January 9, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38186559/catheter-ablation-of-left-ventricular-summit-ectopies-in-left-ventricular-noncompaction
#38
Erdie Cruz Fadreguilan
Left ventricular noncompaction (LVNC) is a rare disorder and the true prevalence is largely unknown. Its clinical presentation is highly variable from being asymptomatic to the presence of heart failure, thromboembolic events, arrhythmias, and even risk of sudden cardiac death. A 37-year-old woman presented with frequent and symptomatic premature ventricular complexes (PVCs) and reduced left ventricular systolic function due to LVNC cardiomyopathy. The PVCs were refractory to medical therapy and the patient underwent successful ablation of the left ventricular summit PVCs...
December 2023: Journal of Medical Cases
https://read.qxmd.com/read/38176771/ultrasound-based-characterization-of-ventricular-tachycardia-scar-and-arrhythmogenic-substrate-the-soundscar-study
#39
JOURNAL ARTICLE
Nathan Denham, Wern Yew Ding, Timothy Campbell, Simon Modi, Vishal Luther, Derick Todd, Saurabh Kumar, Sharad Agarwal, Saagar Mahida
BACKGROUND: Intracardiac echocardiography (ICE) represents a valuable image integration technique, with the unique advantage of dynamic real-time scar characterization. OBJECTIVES: The goals of this study were to assess the correlation between ICE-defined and electroanatomic mapping (EAM)-defined scar in patients with ischemic cardiomyopathy and to define the outcomes of ICE-guided ventricular tachycardia (VT) ablation. METHODS: Thirty-eight patients with ischemic cardiomyopathy (SOUNDSCAR cohort) underwent full left ventricular (LV) ICE imaging and EAM...
January 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38167848/injectable-hydrogel-electrodes-as-conduction-highways-to-restore-native-pacing
#40
JOURNAL ARTICLE
Gabriel J Rodriguez-Rivera, Allison Post, Mathews John, Skylar Buchan, Drew Bernard, Mehdi Razavi, Elizabeth Cosgriff-Hernandez
There is an urgent clinical need for a treatment regimen that addresses the underlying pathophysiology of ventricular arrhythmias, the leading cause of sudden cardiac death. The current report describes the design of an injectable hydrogel electrode and successful deployment in a pig model with access far more refined than any current pacing modalities allow. In addition to successful cardiac capture and pacing, analysis of surface ECG tracings and three-dimensional electroanatomic mapping revealed a QRS morphology comparable to native sinus rhythm, strongly suggesting the hydrogel electrode captures the deep septal bundle branches and Purkinje fibers...
January 2, 2024: Nature Communications
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