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Amoxicillin-clavulanate

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https://www.readbyqxmd.com/read/28647106/-outpatient-consumption-of-antibiotics-with-a-bacterial-resistance-risk-in-2014-in-france
#1
Marie-Céline Casaurancq, Emilie Patras de Campaigno, Manuela Rueter, Bérangère Baricault, Robert Bourrel, Maryse Lapeyre-Mestre, Agnès Sommet
AIM: This article proposes a description of French regional consumption of antibiotics with a bacterial resistance risk (amoxicillin+clavulanic acid, third-generation cephalosporins [C3G] and fluoroquinolones). METHODS: Antibiotics reimbursements data were obtained by Open Medic website. The antibiotic consumption profile has been established using some indicators of the European Surveillance of Antimicrobial Consumption (ESAC) in daily-defined dose per 1000 inhabitants per day (DID) or in percentage...
May 26, 2017: Thérapie
https://www.readbyqxmd.com/read/28638559/comparative-evaluation-of-anti-microbial-effects-of-triple-antibiotic-paste-and-amox-and-its-derivatives-against-e-faecalis-an-in-vitro-study
#2
Manjeet Kaur, Shrikant Kendre, Parmod Gupta, Navneet Singh, Harsimran Sethi, Neha Gupta, Rushil Acharya
BACKGROUND: Enterococcus faecalis is a microorganism commonly detected in asymptomatic, persistent endodontic infections. Triple antibiotic paste has stood the test of time as a proven antibiotic combination against E. Faecalis. However, problems with this include staining of teeth and standardization of the preparation. Thus, the search for better alternatives and better preparation techniques is still on. AIM: To observe the potential of combinations [(Amoxicillin+ Metronidazole, Amoxicillin Clavulanic Acid + Metronidazole; Amoxicillin and Cloxacillin + Metronidazole)] over Triple Antibiotic Paste...
June 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28623550/antibiotic-susceptibility-profiles-among-campylobacter-isolates-obtained-from-international-travelers-between-2007-and-2014
#3
A Post, D Martiny, N van Waterschoot, M Hallin, U Maniewski, E Bottieau, M Van Esbroeck, E Vlieghe, S Ombelet, O Vandenberg, J Jacobs
Campylobacter infection is a common cause of diarrhea among international travelers. We studied antibiotic resistance patterns among Campylobacter isolates obtained from international travelers according to travel destination. Three collections of isolates obtained from international travelers between 2007 and 2014 (Institute of Tropical Medicine, the "Laboratoire Hospitalier Universitaire de Bruxelles "and the Belgian National Reference Centre for Campylobacter) were used. Isolates were tested for minimal inhibitory concentration (MIC) values (E-test macromethod) for fluoroquinolones, macrolides, tetracyclines, amoxicillin-clavulanic acid, and meropenem...
June 17, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28622864/isolation-and-characterization-of-avibacterium-paragallinarum-with-different-nicotinamide-adenine-dinucleotide-requirements
#4
Ok-Mi Jeong, Min-Su Kang, Byung-Woo Jeon, Byung-Kook Choi, Yong-Kuk Kwon, So-Youn Yoon, Patrick J Blackall, Hee-Soo Lee, Suk-Chan Jung, Jae-Hong Kim
Twenty field isolates of Avibacterium paragallinarum were obtained from chickens in South Korea during 2011-2015. The isolates were identified by a HPG-2 PCR assay specific for A. paragallinarum and by biochemical tests. Growth requirements, Page serovars, carbohydrate fermentation patterns, and antimicrobial susceptibility were also examined. Most isolates (16/20) showed the typical requirement for nicotinamide adenine dinucleotide (NAD) and an enriched CO2 atmosphere for growth. One isolate needed increased levels of NAD and serum for good growth...
June 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28620135/ammonium-glycyrrhizin%C3%A2-counteracts-liver-injury-caused-by-lipopolysaccharide-amoxicillin-clavulanate-potassium
#5
Zugong Yu, Feng Wu, Jing Tian, Xuewen Guo, Ran An, Yangyang Guo
We treated isolated chicken primary hepatocytes with lipopolysaccharide/amoxicillin clavulanate potassium (LPS/AC) to model liver injury and investigate its underlying mechanisms. We also used this model to assess the cytoprotective effects of compound ammonium glycyrrhizin (CAG) in vitro. LPS/AC-induced injury decreased cell viability and increased the activity of serum aspartate transaminase and alanine transaminase. Levels of superoxide dismutase, glutathione, and glutathione peroxidase were lower than control, while levels of the oxidative product malondialdehyde and reactive oxygen species were higher...
May 30, 2017: Oncotarget
https://www.readbyqxmd.com/read/28619975/antibiotic-associated-haemorrhagic-colitis-not-always-clostridium-difficile
#6
Olalekan Akanbi, Nasir Saleem, Mohanad Soliman, Bibek Singh Pannu
Antibiotic-associated colitis is a gastrointestinal complication of antibiotic use commonly seen in hospitalised patients, with Clostridium difficile (C. difficile) colitis being the most common type. We present a case of haemorrhagic colitis secondary to Klebsiella oxytoca following self-initiated amoxicillin-clavulanic acid use. An 85-year-old woman presented to the emergency department with abdominal pain and mucobloody diarrhoea. History was notable for an ongoing 5-day course of amoxicillin-clavulanic acid use...
June 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28608133/frequency-associated-factors-and-outcome-of-multi-drug-resistant-intensive-care-unit-acquired-pneumonia-among-patients-colonized-with-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae
#7
Keyvan Razazi, Armand Mekontso Dessap, Guillaume Carteaux, Chloé Jansen, Jean-Winoc Decousser, Nicolas de Prost, Christian Brun-Buisson
BACKGROUND: We assessed prevalence, associated factors and prognosis of extended-spectrum beta-lactamase-producing Enterobacteriaceae pneumonia acquired in intensive care unit (ESBL-PE pneumonia) among carriers. Variables associated with nosocomial pneumonia caused by carbapenem-resistant bacteria (CRB) were also assessed. METHODS: A 6-year prospective study (May 2009-March 2015) in the medical ICU of an 850-bed university-affiliated hospital was conducted. RESULTS: Of the 6303 patients admitted, 843 (13...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28603609/antimicrobial-susceptibility-of-clostridium-difficile-isolated-in-thailand
#8
Papanin Putsathit, Monthira Maneerattanaporn, Pipat Piewngam, Daniel R Knight, Pattarachai Kiratisin, Thomas V Riley
BACKGROUND: Exposure to antimicrobials is the major risk factor associated with Clostridium difficile infection (CDI). Paradoxically, treatment of CDI with antimicrobials remains the preferred option. To date, only three studies have investigated the antimicrobial susceptibility of C. difficile from Thailand, two of which were published in the 1990s. This study aimed to investigate the contemporary antibiotic susceptibility of C. difficile isolated from patients in Thailand. METHODS: A collection of 105 C...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28589415/noma-in-an-hiv-infected-patient-in-guinea-bissau-a-case-report
#9
Tina Madsen, Candida Medina, Sanne Jespersen, Christian Wejse, Bo Langhoff Hønge
BACKGROUND: Noma is a multifactorial and multibacterial opportunistic infection that initially causes necrotic gingivitis but rapidly spreads to the nearby orofacial tissue resulting in sloughing and severe deformation of the facial structures. The majority of cases are seen in young children under the age of 6 years. Noma is strongly associated with poverty, malnutrition and immunosuppression, and is often preceded by severe systemic infections such as measles and malaria. Only few cases of noma infection in adults have been described...
June 6, 2017: Infection
https://www.readbyqxmd.com/read/28583865/breast-abscess-due-to-finegoldia-magna-in-a-non-puerperal-women
#10
Fernando Cobo, Javier Rodríguez-Granger, Antonio Sampedro, José María Navarro-Marí
Finegoldia magna is a Gram-positive anaerobic coccus involved in a wide variety of infections. We report a unusual case of breast abscess in a non-puerperal patient. A 46-year-old woman presented with pain and a nodular lesion in the left breast. Culture of abscess drainage resulted in isolation of F. magna. Initial treatment with clindamycin was changed to a definitive treatment with amoxicillin-clavulanate for 10 days due to resistance to clindamycin, and improvement of this infection was documented.
June 3, 2017: Anaerobe
https://www.readbyqxmd.com/read/28577933/impact-of-selective-reporting-of-antibiotic-susceptibility-test-results-on-the-appropriateness-of-antibiotics-chosen-by-french-general-practitioners-in-urinary-tract-infections-a-randomised-controlled-case-vignette-study
#11
Loic Bourdellon, Nathalie Thilly, Sébastien Fougnot, Céline Pulcini, Sandrine Henard
Selective reporting of antibiotic susceptibility test (AST) results is a potential intervention for laboratory-based antibiotic stewardship. The aim of this study was to assess the impact of AST reporting on the appropriateness of antibiotics selected by French general practitioners for urinary tract infections (UTIs). A randomised controlled case-vignette study in a region of northeast France surveyed general practitioners between July and October 2015 on treatment of four clinical cases of community-acquired Escherichia coli UTIs (two cases of complicated cystitis, one of acute pyelonephritis and one male UTI)...
May 31, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28570834/in-vitro-antistaphylococcal-synergistic-effect-of-isoflavone-metabolite-demethyltexasin-with-amoxicillin-and-oxacillin
#12
Johana Rondevaldova, Jana Hummelova, Jan Tauchen, Ladislav Kokoska
Staphylococcal infections are often hard to treat due to increasing resistance, especially to β-lactams. Previous studies described the synergy between common antibiotics and isoflavonoids; however, little is yet known about the combinatory effects of antibiotics with products of human isoflavone metabolism. In this study, demethyltexasin (DT), a human body metabolite of soybean isoflavones, was evaluated for its possible antistaphylococcal combinatory effect with amoxicillin and oxacillin. For comparison, common therapeutically used combination of amoxicillin/clavulanic acid was tested...
June 1, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28570348/early-infectious-outcomes-following-addition-of-fluoroquinolone-or-aminoglycoside-to-post-trauma-antibiotic-prophylaxis-in-combat-related-open-fracture-injuries
#13
Bradley A Lloyd, Clinton K Murray, Faraz Shaikh, M Leigh Carson, Dana M Blyth, Elizabeth R Schnaubelt, Timothy J Whitman, David R Tribble
BACKGROUND: We examined combat-related open extremity fracture infections as a function of whether post-trauma antimicrobial prophylaxis included expanded Gram-negative (EGN) coverage. METHODS: Military personnel with open extremity fractures sustained in Iraq and Afghanistan (2009-2014) who transferred to participating hospitals in the United States were assessed. The analysis was restricted to patients with a U.S. hospitalization period of ≥7 days. Prophylaxis was classified as narrow (e...
May 30, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28569454/antibiotic-treatment-to-prevent-post-extraction-complications-a-monocentric-randomized-clinical-trial-preliminary-outcomes
#14
Antonio Barone, Francesco S Marchionni, Chiara Cinquini, Andrea Cipolli Panattoni, Paolo Toti, Simone Marconcini, Ugo Covani, Mario Gabriele
BACKGROUND: Tooth extraction is a very common procedure in oral surgery. Despite this, very little information is available in the literature as to the antibiotic management of the patient. The aim of this study is to evaluate whether the antibiotic prophylaxis could be beneficial in preventing post- extraction local complications and whether the use of a probiotic could help reduce the antibiotic gastro-intestinal side effects. MATERIALS AND METHODS: 111 patients meeting the inclusion criteria were initially included in this randomized clinical trial and randomly allocated to one of the three experimental groups according to a computer-generated randomization list...
May 31, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28566083/-a-case-of-coccidioidomycosis-in-turkey-imported-from-the-united-states-of-america
#15
Seniha Başaran, Nilgün Karabıçak, Serap Şimşek Yavuz, Nathan P Wiederhold, Seda Şafak, Aysun Sarıbuğa, Deanna A Sutton, Züleyha Bingöl, Atahan Çağatay, Halit Özsüt, Zeki Kılıçaslan, Haluk Eraksoy
Coccidioidomycosis caused by Coccidioides immitis or Coccidioides posadasii is a rare infectious disease except in endemic regions. In this report the third documented imported case of coccidioidomycosis in Turkey was presented. A thirty-year-old male patient was admitted to our hospital with fever and purulent drainage from his chest tube. He had worked in Arizona, USA, until 4 months before this presentation. While in Arizona, he experienced cough and hemoptysis and was diagnosed as pulmonary coccidioidomycosis...
April 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28561169/-adequate-antibiotic-prophylaxis-and-therapy-of-periprosthetic-infections-of-the-breast-review-of-468-consecutive-implant-removals
#16
Jörn Andreas Lohmeyer, Mai Alawadi, Philipp Alexander Bergmann, Daniel Schmauss, Klaus Stephan Wittig
Background Periprosthetic infections are feared complications in aesthetic as well as in reconstructive breast surgery. The purpose of our study was to evaluate our institution's specific culture data and to identify most common organisms and suitable antibiotics for prophylaxis and first line treatment in implant-based breast surgery. Patients and Methods We analyzed all patients with a change or removal of breast implants in the period from 01.01.2012 to 31.12.2015 retrospectively. Based on the medical records, the surgical indications were identified and specifically analyzed for signs of infection and capsular fibrosis...
April 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28559812/rapid-involution-of-pustules-during-topical-steroid-treatment-of-acute-generalized-exanthematous-pustulosis
#17
Christiane Kley, Carla Murer, Julia-Tatjana Maul, Barbara Meier, Florian Anzengruber, Alexander A Navarini
Acute generalized exanthematous pustulosis (AGEP) is a dramatic generalized pustular rash of severe onset, which is considered a serious cutaneous adverse reaction to drugs. However, even though the clinical features are impressive and are often accompanied by systemic inflammation, it can be controlled quickly and safely by topical steroids subsequent to interruption of the offending drug. Here, we describe the management of a case and the evolution of the pustular rash. An elderly woman consulted with a generalized crop of 2-3 mm, nonfollicular pustules on erythematous background...
January 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28559001/characterizing-non-linear-effects-of-hospitalization-duration-on-antimicrobial-resistance-in-respiratory-isolates-a-retrospective-analysis-of-a-prospective-nationwide-surveillance-system
#18
Rami Sommerstein, Andrew Atkinson, Elia F Lo Priore, Andreas O Kronenberg, Jonas Marschall
OBJECTIVES: Our objective was to systematically study the influence of length of hospital stay on bacterial resistance in relevant respiratory tract isolates. METHODS: Using prospective epidemiological data from the National Swiss Antibiotic Resistance Surveillance System, susceptibility testing results of respiratory isolates retrospectively retrieved from patients hospitalized between 2008-2014 were compiled. Generalized additive models were used to illustrate resistance rates relative to hospitalization duration and to adjust for co-variables...
May 27, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28546029/gardnerella-vaginalis-bacteremia-associated-with-severe-acute-encephalopathy-in-a-young-female-patient
#19
Jacques Tankovic, Albertas Timinskas, Migle Janulaitiene, Milda Zilnyte, Jean-Luc Baudel, Eric Maury, Aurelija Zvirbliene, Milda Pleckaityte
Gardnerella vaginalis is a facultative anaerobic bacterium that inhabits the genitourinary tract of both healthy women and those with bacterial vaginosis. We report a case of G. vaginalis bacteremia associated with severe toxic encephalopathy in a young woman. Anaerobic blood cultures yielded pure growth of small gram-variable rods later identified as G. vaginalis by both rapid biochemical tests and 16S rRNA gene sequencing. The patient recovered after treatment with amoxicillin-clavulanate according to the in vitro susceptibility testing...
May 22, 2017: Anaerobe
https://www.readbyqxmd.com/read/28533857/antibiogram-profile-of-uropathogens-isolated-at-bahir-dar-regional-health-research-laboratory-centre-northwest-ethiopia
#20
Awoke Derbie, Derese Hailu, Daniel Mekonnen, Bayeh Abera, Gashaw Yitayew
INTRODUCTION: Antimicrobial resistance among bacteria that cause urinary tract infection (UTI) has been increasing since the introduction of chemotherapy. This study was aimed to assess the types of isolates from patients with UTI and to determine their current antimicrobial susceptibility profile. METHODS: A record based retrospective analysis of bacterial uropathogens processed in the period of January 2012 to December 2014 at Bahir Dar Health Research Laboratory Center (BRHRLC) was determined...
2017: Pan African Medical Journal
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