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https://www.readbyqxmd.com/read/28231527/rapid-discrimination-and-determination-of-antibiotics-drugs-in-plastic-syringes-using-near-infrared-spectroscopy-with-chemometric-analysis-application-to-amoxicillin-and-penicillin
#1
Laetitia Minh Mai Lê, Luc Eveleigh, Ikram Hasnaoui, Patrice Prognon, Arlette Baillet-Guffroy, Eric Caudron
The aim of this study was to investigate near infrared spectroscopy (NIRS) combined to chemometric analysis to discriminate and quantify three antibiotics by direct measurement in plastic syringes.Solutions of benzylpenicillin (PENI), amoxicillin (AMOX) and amoxicillin/clavulanic acid (AMOX/CLAV) were analyzed at therapeutic concentrations in glass vials and plastic syringes with NIR spectrometer by direct measurement. Chemometric analysis using partial least squares regression and discriminative analysis was conducted to develop qualitative and quantitative calibration models...
February 14, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28230273/comparison-of-pathogen-eradication-rate-and-safety-of-anti-bacterial-agents-for-bronchitis-a-network-meta-analysis
#2
Jinghua Wang, Haiyang Xu, Dunwei Wang, Mingxian Li
OBJECTIVE: A large number of population in both developing and developed countries are affected by bronchitis, among all the factors, bacterial infection was considered as a critical cause of acute exacerbations of chronic bronchitis. Although several anti-bacterial agents were proved to have the effect of alleviating bronchitis, their relative efficacies and potential side effects remained not clear. We are keen to compare the pathogen eradication rate and safety of anti-bacterial agents for bronchitis...
February 23, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28225904/invasive-haemophilus-influenzae-disease-in-the-vaccine-era-in-rio-de-janeiro-brazil
#3
Mari Tuyama, Jessica Corrêa-Antônio, Jessica Schlackman, Jane W Marsh, Maria C Rebelo, Elaine O Cerqueira, Márcio Nehab, Fabíola Kegele, Getúlio F Carmo, Dominique Ca Thielmann, Paulo F Barroso, Lee H Harrison, David E Barroso
BACKGROUND: Haemophilus influenzae (Hi) serotype b (Hib) conjugate vaccine was incorporated into the infant immunisation schedule in Brazil in 1999, where Hib was one of the major etiologic sources of community-acquired bacterial meningitis. OBJECTIVES: The purpose of this study is to describe the molecular epidemiology of invasive Hi disease in Rio de Janeiro state, Brazil, before and after vaccine introduction. METHODS: Surveillance data from 1986 to 2014 were analysed...
March 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28225898/invasive-haemophilus-influenzae-disease-in-the-vaccine-era-in-rio-de-janeiro-brazil
#4
Mari Tuyama, Jessica Corrêa-Antônio, Jessica Schlackman, Jane W Marsh, Maria C Rebelo, Elaine O Cerqueira, Márcio Nehab, Fabíola Kegele, Getúlio F Carmo, Dominique Ca Thielmann, Paulo F Barroso, Lee H Harrison, David E Barroso
BACKGROUND: Haemophilus influenzae (Hi) serotype b (Hib) conjugate vaccine was incorporated into the infant immunisation schedule in Brazil in 1999, where Hib was one of the major etiologic sources of community-acquired bacterial meningitis. OBJECTIVES: The purpose of this study is to describe the molecular epidemiology of invasive Hi disease in Rio de Janeiro state, Brazil, before and after vaccine introduction. METHODS: Surveillance data from 1986 to 2014 were analysed...
February 16, 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28215892/feeding-of-waste-milk-to-holstein-calves-affects-antimicrobial-resistance-of-escherichia-coli-and-pasteurella-multocida-isolated-from-fecal-and-nasal-swabs
#5
G Maynou, A Bach, M Terré
The use of milk containing antimicrobial residues in calf feeding programs has been shown to select for resistant fecal Escherichia coli in dairy calves. However, information is scarce about the effects of feeding calves waste milk (WM) on the prevalence of multidrug-resistant bacteria. The objective of this study was to determine the antimicrobial resistance patterns of fecal E. coli and nasal Pasteurella multocida isolates from calves fed either milk replacer (MR) or WM in 8 commercial dairy farms (4 farms per feeding program)...
February 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28209132/urinary-tract-infection-among-fistula-patients-admitted-at-hamlin-fistula-hospital-addis-ababa-ethiopia
#6
Matifan Dereje, Yimtubezinesh Woldeamanuel, Daneil Asrat, Fekade Ayenachew
BACKGROUND: Urinary Tract Infection (UTI) causes a serious health problem and affects millions of people worldwide. Patients with obstetric fistula usually suffer from incontinence of urine and stool, which can predispose them to frequent infections of the urinary tract. Therefore the aim of this study was to determine the etiologic agents, drug resistance pattern of the isolates and associated risk factor for urinary tract infection among fistula patients in Addis Ababa fistula hospital, Ethiopia...
February 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28207509/relationship-between-drug-resistance-and-the-clustered-regularly-interspaced-short-palindromic-repeat-associated-protein-genes-cas1-and-cas2-in-shigella-from-giant-panda-dung
#7
Lu Ren, Lin-Hua Deng, Ri-Peng Zhang, Cheng-Dong Wang, De-Sheng Li, Li-Xin Xi, Zhen-Rong Chen, Rui Yang, Jie Huang, Yang-Ru Zeng, Hong-Lin Wu, San-Jie Cao, Rui Wu, Yong Huang, Qi-Gui Yan
BACKGROUND: To detect drug resistance in Shigella obtained from the dung of the giant panda, explore the factors leading to drug resistance in Shigella, understand the characteristics of clustered, regularly interspaced, short, palindromic repeats (CRISPR), and assess the relationship between CRISPR and drug resistance. METHODS: We collected fresh feces from 27 healthy giant pandas in the Giant Panda Conservation base (Wolong, China). We identified the strains of Shigella in the samples by using nucleotide sequence analysis...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28199151/antimicrobial-resistance-percentages-of-salmonella-and-shigella-in-seafood-imported-to-jordan-higher-percentages-and-more-diverse-profiles-in-shigella
#8
Mohammad M Obaidat, Alaa E Bani Salman
This study determined the prevalence and antimicrobial resistance of human-specific ( Shigella spp.) and zoonotic ( Salmonella enterica ) foodborne pathogens in internationally traded seafood. Sixty-four Salmonella and 61 Shigella isolates were obtained from 330 imported fresh fish samples from Egypt, Yemen, and India. The pathogens were isolated on selective media, confirmed by PCR, and tested for antimicrobial resistance. Approximately 79 and 98% of the Salmonella and Shigella isolates, respectively, exhibited resistance to at least one antimicrobial, and 8 and 49% exhibited multidrug resistance (resistance to three or more antimicrobial classes)...
February 15, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28193184/survey-of-spanish-general-practitioners-attitudes-toward-management-of-sore-throat-an-internet-based-questionnaire-study
#9
Carl Llor, Isabel Vilaseca, Eduardo Lehrer-Coriat, Xavier Boleda, José L Cañada, Ana Moragas, Josep M Cots
BACKGROUND: The management of sore throat varies widely in Europe. The objective of this study was to gain insight into clinicians' perceptions on the current management of sore throat in Spain. METHODS: Cross-sectional, internet-based questionnaire study answered from July to September 2013. General practitioners (GPs) affiliated with the two largest scientific societies of primary care were invited to participate in the study. Questions were asked about physician knowledge, the use of current national guidelines for sore throat management, and management in two clinical scenarios, depicting a young adult with sore throat and: 1...
February 14, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28178108/a-hospital-based-case-control-study-of-diarrhea-in-children-in-shanghai
#10
Hailing Chang, Ling Zhang, Yanling Ge, Jiehao Cai, Xiangshi Wang, Zheng Huang, Jiayin Guo, Hao Xu, Zhen Gu, Hong Chen, Xuebin Xu, Mei Zeng
BACKGROUND: Prevention and control of childhood diarrhea is a global priority. We conducted a case-control study of childhood diarrhea in Shanghai. METHODS: We prospectively recruited diarrheal children in an outpatient setting. Non-diarrheal controls were individually matched to cases. Rotavirus, norovirus and bacterial pathogens were examined. Clinical and epidemiologic data were obtained at enrollment and follow-up. RESULTS: Potential pathogens identified in 680 diarrheal cases and 680 controls were rotavirus (19...
February 6, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28161910/associations-of-gender-and-a-proxy-of-female-menopausal-status-with-histological-features-of-drug-induced-liver-injury
#11
Ayako Suzuki, Huiman Barnhart, Jiezhun Gu, Herbert L Bonkovsky, Hans L Tillmann, Robert J Fontana, David E Kleiner
Gender and menopause may contribute to type and severity of drug-induced liver injury (DILI) by influencing host responses to injury. The aim of this study was to assess the associations of gender and female age 50 [a proxy of menopause] with histologic features of liver injury in 212 adults enrolled in the Drug-Induced Liver Injury Network (DILIN) registry METHODS: All participants had a causality score of at least 'probable', a liver biopsy within 30 days of DILI onset, and no prior chronic liver disease...
February 5, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28145856/class-i-integron-and-%C3%AE-lactamase-encoding-genes-of-multidrug-resistance-salmonella-isolated-from-pigeons-and-their-environments
#12
S Yousef, R Mamdouh
Seroprevalence of Salmonella spp. was investigated in pigeon and its surrounding environment of Sharkia province, Egypt. Samples were randomly collected from fifty freshly dead squabs, forty freshly dead adults pigeons, sixty diseased adult pigeons and 100 apparently healthy adult pigeons. Bacterial isolates were tested for their susceptibility to 17 different antimicrobial discs, by using the disc diffusion method. The bacterial isolates were tested for Class I and β-lactamase encoding genes by using PCR...
December 30, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28144190/antibiotic-resistance-in-urinary-isolates-of-escherichia-coli
#13
Amila Abduzaimovic, Mufida Aljicevic, Velma Rebic, Sabina Mahmutovic Vranic, Kadrija Abduzaimovic, Sabina Sestic
OBJECTIVES: The aim of this study was to examine the presence of antimicrobial resistance / susceptibility strains of Escherichia coli in inpatients and outpatients. MATERIALS AND METHODS: It is a retrospective study carried out at the Department of Microbiology, Parasitology and Virology Faculty of Medicine, University of Sarajevo. In cooperation with the Microbiological laboratory of the Cantonal Hospital Zenica and the Microbiological laboratory of the General Hospital Tesanj, 3863 urine samples were processed in the period from March 1(st) to March 31(st) 2016...
December 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/28137797/a-whole-genome-sequencing-approach-to-study-cefoxitin-resistant-salmonella-enterica-serovar-heidelberg-from-various-sources
#14
Romaine Edirmanasinghe, Rita Finley, E Jane Parmley, Brent P Avery, Carolee Carson, Sadjia Bekal, George Golding, Michael R Mulvey
This study characterized cefoxitin-resistant and susceptible Salmonella enterica serovar Heidelberg from human, abattoir poultry, and retail poultry to assess the molecular relationships of isolates from these sources in Québec in 2012. Isolates were collected as part of the Canadian Integrated Program for Antimicrobial Resistance Surveillance (CIPARS). All isolates were subjected to antimicrobial susceptibility testing, polymerase chain reaction (PCR) for CMY-2, pulsed-field gel electrophoresis (PFGE), and whole genome sequencing (WGS)...
January 30, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28137277/antimicrobial-resistance-in-coagulase-negative-staphylococci-from-nigerian-traditional-fermented-foods
#15
P T Fowoyo, S T Ogunbanwo
BACKGROUND: Coagulase-negative staphylococci have become increasingly recognized as the etiological agent of some infections. A significant characteristic of coagulase-negative staphylococci especially strains isolated from animals and clinical samples is their resistance to routinely used antibiotics although, resistant strains isolated from fermented foods have not been fully reported. METHODS: A total of two hundred and fifty-five CoNS isolates were subjected to antimicrobial susceptibility test using the disc diffusion technique...
January 31, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28134402/-severe-neutropenia-during-treatment-with-amoxicillin-clavulanic-acid-in-a-patient-on-regular-hemodialysis-treatment
#16
Nicola Spetrino, Marta Arazzi, Giorgia Di Fulvio, Federica Giunta, Xhensila Grabocka, Maria Olimpia Longo, Gabriella Micioni, Alessandro Pezzutto, Simona Silvestri, Marco Tondo, Giacinta Vigilante, Mario Bonomini
Beta-lactams are one of the most widely used antibiotics in respiratory diseases, both in adults and in the pediatric population. Their widespread use is also linked to the elevated tolerability and low risk of side effects that are generally not severe. We present here the case of a patient on regular haemodialysis pertaining to our Center who, after a seven-day treatment period with amoxicillin/clavulanic acid antibiotic therapy (medication originator), developed a framework of severe neutropenia (neutrophils till 10/mmc) resulting in hospitalization and the beginning of a specific diagnostic and therapeutic work-up...
November 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28124956/-investigation-of-the-frequency-and-distribution-of-beta-lactamase-genes-in-the-clinical-isolates-of-acinetobacter-baumannii-collected-from-different-regions-of-turkey-a-multicenter-study
#17
Fatih Şaban Beriş, Emine Esra Budak, Duygu Gülek, Aytül Uzun, Zeynep Çizmeci, Fırat Zafer Mengeloğlu, Şahin Direkel, Yeliz Çetinkol, Yasemin Ay Altıntop, Meryem Iraz, Tuba Dal, Safiye Umut Say Coşkun, Pervin Özlem Balcı, Tuba Kayman, Ahmet Çalışkan, Yelda Yazıcı, İsmail Tosun, Ayşe Ertürk, Ayşegül Çopur Çiçek
The diversity and distribution of TEM, SHV and CTX-M type of extended-spectrum beta-lactamases (ESBLs) are important for the treatment and control of infections. Determination of ESBL genes in clinical isolates by polymerase chain reaction (PCR) and DNA sequencing can obtain useful data for their molecular epidemiology and risk. The aim of this study was to investigate the frequency of beta-lactamase genes in Acinetobacter baumannii strains isolated from different regions of Turkey. A total of 519 A.baumannii strains collected from hospitals located at 12 different provinces of Turkey (Bolu (n= 67), Tokat (n= 47), Trabzon (n= 25), Ordu (n= 27), Diyarbakır (n= 47), Niğde (n=31), Kayseri (n= 36), Ankara (n= 41), Kirikkale (n= 26), Kahramanmaraş (n= 25), Mersin (n= 40), Istanbul (n= 107)] between 2011-2012 period were included in the study...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28122841/antibiotic-management-of-children-with-infectious-diseases-in-dutch-primary-care
#18
Anne R J Dekker, Theo J M Verheij, Alike W van der Velden
BACKGROUND: Childhood infections are common in general practice. Although clinical guidelines recommend restrictive antibiotic use for children, antibiotics are too often prescribed. OBJECTIVE: The aim of this study was to obtain insight in antibiotic prescribing for children related to clinical diagnoses. This is pivotal to define improvement strategies in the antibiotic management. METHODS: In this observational study, we used consultation data collected from 45 general practices in the Netherlands in 2012...
January 24, 2017: Family Practice
https://www.readbyqxmd.com/read/28122629/bacteremia-caused-by-multidrug-resistant-bacteria-among-hospitalized-malnourished-children-in-mwanza-tanzania-a-cross-sectional-study
#19
Maimuna Ahmed, Mariam M Mirambo, Martha F Mushi, Adolfine Hokororo, Stephen E Mshana
BACKGROUND: Severe malnutrition has been known to increase susceptibility and severity of infections. Bacteremia in malnourished children has been found to increase morbidity and mortality especially if is due to multidrug resistant bacteria. Here, we report the prevalence of bacteremia among children under 5 years of age and the antibiotic susceptibility pattern of the isolates; the information that can be used by clinicians to guide on the empirical antibiotic treatment. FINDINGS: A total of 402 malnourished children were investigated for bacteremia...
January 25, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28122105/acetylcysteine-in-the-treatment-of-subacute-sinusitis-a-double-blind-placebo-controlled-clinical-trial
#20
Mehrzad Bahtouee, Gholamhosein Monavarsadegh, Mohammadjavad Ahmadipour, Mazyar Motieilangroodi, Niloofar Motamed, Jamshid Saberifard, Seyyedsajjad Eghbali, Hooman Adibi, Hesam Maneshi, Hasan Malekizadeh
Sinusitis is a common disease with harmful effects on the health and finances of patients and the economy of the community. It is easily treated in most of its acute stages but is associated with some management difficulties as it goes toward chronicity. Therefore, we tried to improve the treatment of subacute sinusitis by using acetylcysteine, which is a safe mucolytic and antioxidant agent. Thirty-nine adult patients with subacute sinusitis proved by computed tomography (CT) were enrolled in a double-blind, placebo-controlled trial...
January 2017: Ear, Nose, & Throat Journal
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