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https://www.readbyqxmd.com/read/29475169/raoultella-planticola-associated-necrotizing-appendicitis-a-novel-case-report
#1
Gayathri Naganathan, Nalin Kumar Amin
INTRODUCTION: Raoultella Planticola is a gram negative, aerobic, rod bacteria found in water and soil and is rarely reported to cause infections in humans. This case study is the first of its kind in reporting R. planticola appendicitis. PRESENTATION OF CASE: We report a case of a woman presenting with a two-day history of increased weakness, fatigue and anorexia, localized pain to the right lower quadrant, and elevated white blood cell count. CT results demonstrated acute uncomplicated appendicitis which was managed via laparoscopic appendectomy...
February 9, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29461916/outpatient-management-of-fever-and-neutropenia-in-adults-treated-for-malignancy-american-society-of-clinical-oncology-and-infectious-diseases-society-of-america-clinical-practice-guideline-update
#2
Randy A Taplitz, Erin B Kennedy, Eric J Bow, Jennie Crews, Charise Gleason, Douglas K Hawley, Amelia A Langston, Loretta J Nastoupil, Michelle Rajotte, Kenneth Rolston, Lynne Strasfeld, Christopher R Flowers
Purpose To provide an updated joint ASCO/Infectious Diseases Society of American (IDSA) guideline on outpatient management of fever and neutropenia in patients with cancer. Methods ASCO and IDSA convened an Update Expert Panel and conducted a systematic review of relevant studies. The guideline recommendations were based on the review of evidence by the Expert Panel. Results Six new or updated meta-analyses and six new primary studies were added to the updated systematic review. Recommendations Clinical judgment is recommended when determining which patients are candidates for outpatient management, using clinical criteria or a validated tool such as the Multinational Association of Support Care in Cancer risk index...
February 20, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29460795/evidence-the-u-s-autism-epidemic-initiated-by-acetaminophen-tylenol-is-aggravated-by-oral-antibiotic-amoxicillin-clavulanate-augmentin-and-now-exponentially-by-herbicide-glyphosate-roundup
#3
Peter Good
Because certain hereditary diseases show autistic behavior, and autism often runs in families, researchers seek genes underlying the pathophysiology of autism, thus core behaviors. Other researchers argue environmental factors are decisive, citing compelling evidence of an autism epidemic in the United States beginning about 1980. Recognition that environmental factors influence gene expression led to synthesis of these views - an 'epigenetic epidemic' provoked by pervasive environmental agents altering expression of vulnerable genes, inducing characteristic autistic biochemistries in many mothers and infants...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29458548/amoxicillin-tolerant-pasteurella-multocida-strain-isolated-from-chronic-dermohypodermitis-after-suboptimal-exposure-to-amoxicillin-is-not-associated-with-reduced-growth-rate
#4
A Limelette, D Giusti, D Anuset, C Beaupuis, H Jacquier, C De Champs, F Bani-Sadr, T Guillard, Y N'Guyen
Pasteurella multocida is rarely observed in human chronic infections. A Pasteurella multocida strain was isolated from a skin biopsy of chronic dermohypodermitis in a 21-year-old woman without an immunocompromised state. As this strain was viable one month after a cat scratch despite treatment by amoxicillin-clavulanic acid, we compared this strain's growth rate, amoxicillin Minimal Inhibitory and Bactericidal Concentrations (MIC and MBC), resistance to serum and ability to activate neutrophil granulocytes with those of control strains isolated during acute infections in humans without previous antibiotics exposure...
February 13, 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29448094/the-prevalence-and-antimicrobial-resistance-of-listeria-spp-in-raw-milk-and-traditional-dairy-products-delivered-in-yazd-central-iran-2016
#5
Fateme Akrami-Mohajeri, Zahra Derakhshan, Margherita Ferrantee, Negar Hamidiyan, Meysam Soleymani, Gea Oliveri Conti
Listeria monocytogenes is an important foodborne pathogen which its data in Iranian dairy products is limited. A total of 545 samples of traditional dairy products (raw milk, traditional cheese, traditional butter, traditional curd, and traditional ice cream) were collected from traditional dairy shops located in Yazd, Iran. L. monocytogenes was isolated, and positive samples were confirmed by polymerase chain reaction. Antibiotic sensitivity test was conducted to determine the antibiotic resistance. Listeria species were isolated from 11...
February 12, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29447900/microbiology-and-antibiotic-therapy-of-subperiosteal-orbital-abscess-in-children-with-acute-ethmoiditis
#6
A Coudert, S Ayari-Khalfallah, P Suy, E Truy
OBJECTIVE: The objective of this study was to investigate the microbiological cultures and the management of acute ethmoiditis complicated by subperiosteal orbital abscess (SPOA) in a pediatric population. METHODS: The medical records of children under 18 years old was performed in a tertiary referral pediatric center from January 2009 to April 2017. Clinical examination, computed tomography scans, medical and surgical treatments were reviewed and compared to other studies in literature...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447384/antimicrobial-prophylaxis-with-combat-related-open-soft-tissue-injuries
#7
Bradley A Lloyd, Clinton K Murray, Faraz Shaikh, M Leigh Carson, Dana M Blyth, Elizabeth R Schnaubelt, Timothy J Whitman, David R Tribble
Introduction: All Department of Defense (DoD) guidance documents recommend cefazolin or clindamycin as post-trauma antibiotic prophylaxis for open soft-tissue injuries. Although not advocated, some patients with open soft-tissue injuries also received expanded Gram-negative coverage (EGN) prophylaxis based on the judgment of front-line trauma providers. During the study period, revised guidelines in 2011/2012 re-emphasized recommendations for using cefazolin or clindamycin, and stewardship efforts in the DoD trauma community aimed to reduce the practice of adding EGN to guideline-recommended antibiotic prophylaxis...
February 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29441201/leech-management-before-application-on-patient-a-nationwide-survey-of-practices-in-french-university-hospitals
#8
Delphine Grau, Raphaël Masson, Maxime Villiet, Brigitte Lamy
Background: Leech therapy in plastic/reconstructive microsurgery significantly improves a successful outcome of flap salvage but the drawback is a risk of severe infection that results in a drop of the salvage rates from 70-80% to below 30%. We report the results of a national survey conducted in all the French university hospitals to assess the current extent of use of leech for medical practices in the hospital and to investigate maintenance, delivery practices and prevention of the risk of infection...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29438535/discrepancies-in-national-time-trends-of-outpatient-antibiotic-utilization-using-different-measures-a-population-based-study-in-france
#9
Nhung T H Trinh, Pierre Chahwakilian, Tim A Bruckner, Stéphane Sclison, Corinne Levy, Martin Chalumeau, Dejan Milic, Robert Cohen, Jérémie F Cohen
Objectives: To assess time trends of outpatient antibiotic utilization using different measures and explore their discrepancies. Methods: Based on French sales data from the IQVIA SDM database, 2009-16, we assessed time trends in outpatient antibiotic utilization using PrID, DID, PID and SID (defined as the number of prescriptions, DDDs, packages and standard units per 1000 inhabitants per day, respectively). We explored discrepancies between trends in PrID and DID by modelling the number of DDDs per prescription...
February 9, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29425733/polymicrobial-anaerobic-bacteremia-due-to-atopobium-rimae-and-parvimonas-micra-in-a-patient-with-cancer
#10
Fernando Cobo, Jaime Borrego, Ma Dolores Rojo, José María Navarro-Marí
Atopobium rimae and Parvimonas micra are both Gram-positive anaerobes involved infrequently in human infections. We report a polymicrobial anaerobic bacteremia caused by these microorganisms. A 43-year-old woman receiving coadjuvant chemotherapy due to a retroperitoneal leiomiosarcoma presented with nausea, vomiting, abdominal pain and fever (38 °C). The two blood cultures resulted in isolation of A. rimae and P. micra, being identified at species level by matrix assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF MS) technology with high log scores...
February 6, 2018: Anaerobe
https://www.readbyqxmd.com/read/29422058/an-evaluation-of-e-coli-in-urinary-tract-infection-in-emergency-department-at-kamc-in-riyadh-saudi-arabia-retrospective-study
#11
Menyfah Q Alanazi, Fulwah Y Alqahtani, Fadilah S Aleanizy
BACKGROUND: Urinary tract infection (UTIS) is a common infectious disease in which level of antimicrobial resistance are alarming worldwide. Therefore, this study aims to describe the prevalence and the resistance pattern of the main bacteria responsible for UTIS Escherichia coli (E. coli). METHODS: Retrospective chart review for patients admitted to emergency department and diagnosed with UTIS at KAMC, in Riyadh, Saudi Arabia between January to March 2008 was performed...
February 9, 2018: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29413671/the-prevalence-of-clostridium-difficile-in-cattle-and-sheep-carcasses-and-the-antibiotic-susceptibility-of-isolates
#12
Hamparsun Hampikyan, Enver Baris Bingol, Karlo Muratoglu, Esra Akkaya, Omer Cetin, Hilal Colak
Clostridium difficile is an anaerobic, spore forming, rod shaped bacterium frequently isolated from butchery animals in recent years. The aim of this study is to evaluate the presence of C. difficile (especially ribotype 027 and 078) in cattle and sheep carcasses and to investigate the antibiotic susceptibility of isolates. The bacterium was isolated in 83 out of 247 (33.6%) cattle and 78 out of 308 (25.3%) sheep carcass samples. 15/83 (18.1%) cattle and 6/78 (7.7%) sheep isolates were identified as ribotype 027, whereas the other hypervirulent isolate ribotype 078 could not be detected among the analysed samples...
January 31, 2018: Meat Science
https://www.readbyqxmd.com/read/29408407/antimicrobial-susceptibility-survey-on-bacterial-agents-of-canine-and-feline-urinary-tract-infections-weight-of-the-empirical-treatment
#13
Elisa Rampacci, Marco Bottinelli, Valentina Stefanetti, Doreene R Hyatt, Elisa Sgariglia, Mauro Coletti, Fabrizio Passamonti
OBJECTIVES: This work characterizes the antimicrobial susceptibility of uropathogens isolated from empirically treated dogs and cats. Within-household transmission of uropathogens can involve humans and companion animals. Knowledge on the prevalence and susceptibility pattern of isolates from canine and feline urine samples and the impact of prior antimicrobial treatment is important to prevent the dissemination of antimicrobial resistance. METHODS: A retrospective study was conducted selecting antibiotically treated companion animals...
February 3, 2018: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29408033/relative-performance-of-antimicrobial-susceptibility-assays-on-clinical-escherichia-coli-isolates-from-animals
#14
Skye Badger, Sam Abraham, Sugiyono Saputra, Darren J Trott, John Turnidge, Tahlia Mitchell, Charles G B Caraguel, David Jordan
The assessment of antimicrobial resistance in bacteria derived from animals is often performed using the disc diffusion assay. However broth-microdilution is the preferred assay for national antimicrobial resistance surveillance programs. This study aimed to evaluate the accuracy of disc diffusion relative to broth-microdilution across a panel of 12 antimicrobials using data from a collection of 994 clinical Escherichia coli isolates from animals. Disc diffusion performance was evaluated by diagnostic sensitivity, specificity, likelihood ratio pairs and receive-operating characteristic (ROC) analysis...
February 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29405759/chemical-composition-antioxidant-and-antibacterial-activity-of-bunium-persicum-eucalyptus-globulus-and-rose-water-on-multidrug-resistant-listeria-species
#15
Farhad Sharafati Chaleshtori, Mohamad Saholi, Reza Sharafati Chaleshtori
This research was aimed at investigating the antioxidant and antibacterial activity of Bunium persicum, Eucalyptus globulus, and rose water on multidrug-resistant Listeria species. The antibiotic resistance of Listeria spp obtained from seafood samples were determined by the Kirby-Bauer method. The antioxidant and antibacterial activity of the essential oils and extracts were evaluated using ferric reducing antioxidant power and microdilution methods, respectively. A total 2 samples (1.88%) were positive for Listeria spp...
January 2018: J Evid Based Integr Med
https://www.readbyqxmd.com/read/29404489/drug-induced-cholestasis
#16
REVIEW
Vinay Sundaram, Einar S Björnsson
Cholestatic drug-induced liver injury (DILI) can be a diagnostic challenge due to a large differential diagnosis, variability in clinical presentation, and lack of serologic biomarkers associated with this condition. The clinical presentation of drug-induced cholestasis includes bland cholestasis, cholestatic hepatitis, secondary sclerosing cholangitis, and vanishing bile duct syndrome. The associate mortality of cholestatic DILI can be as high as 10%, and thus prompt recognition and removal of the offending agent is of critical importance...
October 2017: Hepatology Communications
https://www.readbyqxmd.com/read/29395563/-bacteriology-of-acute-exacerbations-of-chronic-obstructive-pulmonary-disease-in-tunisia
#17
S Messous, M H Grissa, K Beltaief, R Boukef, S Nouira, M Mastouri
INTRODUCTION: The role of bacteria, including atypical organisms, in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) has been assessed in various ways in Tunisia. METHODS: This was a descriptive and analytical study of patients with a mean age of 68.3±10.5 years hospitalized for AECOPD. Bacteriological examination included a cytological sputum exam and serology for atypical organisms including Mycoplasma pneumoniae, Coxiella burnetii, Chlamydophila pneumoniae and Legionella pneumophila using standard techniques...
January 29, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29390976/probiotics-and-infective-endocarditis-in-patients-with-hereditary-hemorrhagic-telangiectasia-a-clinical-case-and-a-review-of-the-literature
#18
Evangelo Boumis, Alessandro Capone, Vincenzo Galati, Carolina Venditti, Nicola Petrosillo
BACKGROUND: In the last decades, probiotics have been widely used as food supplements because of their putative beneficial health effects. They are generally considered safe but rare reports of serious infections caused by bacteria included in the definition of probiotics raise concerns on their potential pathogenic role in patients with particular predisposing factors. Patients with hereditary hemorrhagic telangiectasia (HHT) are exposed to infections because of telangiectasias and arteriovenous malformations (AVMs)...
February 1, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29368165/antibiotic-resistance-in-e-coli-isolates-from-patients-with-urinary-tract-infections-presenting-to-the-emergency-department
#19
Florian Hitzenbichler, Michaela Simon, Thomas Holzmann, Michael Iberer, Markus Zimmermann, Bernd Salzberger, Frank Hanses
PURPOSE: Escherichia coli urine isolates from patients presenting to the emergency department at a German tertiary care hospital were retrospectively analyzed from January 2015-March 2017 to determine antibiotic resistance patterns and patient risk factors for resistance. METHODS: Uncomplicated urinary tract infection (UTI) was defined as UTI in the otherwise healthy patient without relevant co-morbidities and complications. Patients were assumed to have UTI if diagnosis was made by the attending physician with conclusive dipstick results...
January 24, 2018: Infection
https://www.readbyqxmd.com/read/29358784/-uncomplicated-urinary-tract-infections-antimicrobial-susceptibility-study-in-navarre
#20
A Aguinaga, A Gil-Setas, A Mazón Ramos, A Alvaro, J J García-Irure, A Navascués, C Ezpeleta Baquedano
BACKGROUND: Urinary tract infection (UTI) is a high prevalence infection at the community level. In order to improve the adequacy of the empirical therapy, we evaluated the etiology and the resistance pattern of the main uropathogens responsible for community acquired UTI in Navarre. METHODS: Retrospective study (2014-2016) in which we included microorganisms recovered with significant counts from samples of patients with community-acquired UTI. The global etiology and etiology according to age and sex was analyzed...
January 23, 2018: Anales del Sistema Sanitario de Navarra
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