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https://www.readbyqxmd.com/read/29668032/presence-of-meniscus-tear-alters-gene-expression-profile-of-anterior-cruciate-ligament-tears
#1
Robert H Brophy, Marcus A Rothermich, Eric D Tycksen, Lei Cai, Muhammad Farooq Rai
Anterior cruciate ligament (ACL) tears occur in isolation or in tandem with other intra-articular injuries such as meniscus tears. The impact of injury pattern on the molecular biology of the injured ACL is unknown. Here, we tested the hypothesis that the biological response of the ACL to injury varies based on the presence or absence of concomitant meniscus tear. We performed RNA-seq on 28 ACL tears remnants (12 isolated, 16 combined). In total, 16,654 transcripts were differentially-expressed between isolated and combined injury groups at false-discovery-rate of 0...
April 18, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29667926/proximal-tibia-stress-fracture-with-osteoarthritis-of-knee-radiological-and-functional-analysis-of-one-stage-tka-with-long-stem
#2
Dhanasekaran Soundarrajan, Natesan Rajkumar, Palanisamy Dhanasekararaja, Shanmuganathan Rajasekaran
INTRODUCTION: Proximal tibia stress fractures with knee osteoarthritis pose a challenging situation. We evaluated the radiological and functional outcome of one-stage total knee arthroplasty (TKA) and long stem for patients with varied grades of knee arthritis and proximal tibia stress fractures.  Methods: We analysed 20 patients from April 2012 to March 2017 with proximal tibia stress fractures associated with knee osteoarthritis of varied grades. Out of 20 patients, five were acute fresh fractures...
2018: SICOT-J
https://www.readbyqxmd.com/read/29667853/evaluation-and-management-of-subchondral-calcium-phosphate-injection-technique-to-treat-bone-marrow-lesion
#3
Diego Costa Astur, Eduardo Vasconcelos de Freitas, Pedro Barreira Cabral, Caio Carvalho Morais, Bruno Silveira Pavei, Camila Cohen Kaleka, Pedro Debieux, Moises Cohen
Purpose This study aimed to compile available data in medical literature about subchondral calcium phosphate injection, comparing results obtained with this technique, as well as indications, complications, and other important factors in treatment of bone marrow lesions. Designs A literature review using PubMed and Medline database in order to identify works with terms "subchondral calcium phosphate injection," " subchondroplasty®," "bone marrow lesion," and "knee." Eight relevant articles were found...
April 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29667235/contrast-enhanced-computed-tomography-cect-attenuation-is-associated-with-stiffness-of-intact-knee-cartilage
#4
Reza Nickmanesh, Rachel C Stewart, Brian D Snyder, Mark W Grinstaff, Bassam A Masri, David R Wilson
Contrast-enhanced computed tomography (CECT) using charged contrast-agents enables quantification of cartilage glycosaminoglycan content. Since glycosaminoglycan content is a key determinant of cartilage compressive stiffness, CECT measurements have the potential to non-invasively assess cartilage stiffness. The objective of this study was to determine whether CECT attenuation, using a cationic contrast-agent (CA4 +), correlates with the stiffness of intact cartilage. Six fresh femoral and six fresh tibial compartments with intact cartilage were obtained from patients undergoing total knee replacement surgery...
April 17, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29666689/painful-pes-anserine-bursitis-following-total-knee-replacement-surgery-two-cases
#5
Mohamed A M Ariff, Mohd I A C Ros, Nor H M Yahaya
Pes anserine bursitis (PAB) is an inflammation of the bursa located between the medial aspect of the tibia and the hamstring muscles. It is common in patients with degenerative or inflammatory knee arthritis, usually has a self-limiting course and tends to respond well to conservative treatment. However, painful PAB directly following total knee replacement surgery is rare. We report two such cases who were diagnosed via ultrasonography at the Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, in 2015...
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29666082/knee-joint-instability-after-total-knee-replacement-in-a-patient-with-ehlers-danlos-syndrome-the-role-of-insert-changes-as-practical-solution
#6
Ajmal Farid, Stefan Beekhuizen, Joris van der Lugt, Marijn Rutgers
Treatment of knee joint instability in patients with hypermobile Ehlers-Danlos syndrome (EDS) can be challenging. A 53-year-old woman with hypermobile EDS underwent bilateral total knee replacement (TKR) due to valgus osteoarthritis. During follow-up, she developed hypermobility of both knee replacements. Revision of the insert resolved the issue in her left knee; however, the right TKR required two insert exchanges and unfortunately instability persisted. Therefore, a revision to a constrained prosthesis was performed...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29666029/modern-day-bicruciate-retaining-total-knee-arthroplasty-a-short-term-review-of-146-knees
#7
Omar K Alnachoukati, Roger H Emerson, Elizabeth Diaz, Emily Ruchaud, Kwame A Ennin
BACKGROUND: Bicruciate retaining (BCR) implants were first proposed in the 1960s with the polycentric knee. Given the technical difficulty of implanting these devices, and the mixed results at the time, the BCR concept had stalled, until recently. This study seeks to provide a short-term review of the BCR implant design, describe patient-reported outcomes, and discuss key aspects to ensure successful implantation of the modern-day BCR implant design. METHODS: Between October 2014 and December 2016, the senior author performed 146 primary total knee arthroplasties using BCR implants...
March 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29665835/the-efficacy-of-intravenous-aminocaproic-acid-in-primary-total-hip-and-knee-arthroplasty-a-meta-analysis
#8
Yong-Jiang Li, Bi-Sheng Xu, Sun-Peng Bai, Xiao-Jun Guo, Xiang-Yuan Yan
BACKGROUND: We conducted a meta-analysis from randomized controlled trials (RCTs) and non-RCTs to assess the efficacy of aminocaproic acid in cases of primary total hip arthroplasty (THA) or total knee arthroplasty (TKA). METHODS: Potentially relevant academic articles were identified from the Cochrane Library, MEDLINE (1966-2017 October 31), PubMed (1966-2017 October 31), EMBASE (1980-2017 October 31), and ScienceDirect (1985-2017 October 31). Secondary sources were identified from the references of the included literature...
April 17, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29665830/implementation-of-telemedicine-for-knee-osteoarthritis-study-protocol-for-a-randomized-controlled-trial
#9
Zhengping Huang, Xia Pan, Weiming Deng, Zhixiang Huang, Yukai Huang, Xuechan Huang, Zhaohua Zhu, Weiyu Han, Shaoling Zheng, Xin Guo, Changhai Ding, Tianwang Li
BACKGROUND: Osteoarthritis (OA) is the most prevalent chronic joint disease, characterized by joint structural deterioration, pain and loss of function among the elders. It is also associated with several extra-articular symptoms (fatigue, sleep disorders, anxiety and depression) and a reduction of life quality. Studies have revealed that patients with OA benefitted from enhanced management via telemedicine. Guangdong Online Hospital (GOH) is the first officially recognized web-based hospital that provides telemedicine service in China...
April 17, 2018: Trials
https://www.readbyqxmd.com/read/29665764/unicompartmental-knee-arthroplasty-for-spontaneous-osteonecrosis-of-the-knee-a-meta-analysis
#10
Julio J Jauregui, Christopher L Blum, Neil Sardesai, Craig Bennett, R Frank Henn, Farshad Adib
BACKGROUND: Spontaneous osteonecrosis of the knee (SONK) is a poorly understood but debilitating disease entity. Total knee arthroplasty (TKA) is the standard of care for those patients who fail conservative management, but considering SONK's predilection for affecting a single knee compartment, unicompartmental knee arthroplasty (UKA) appears to be a more tailored option. Unfortunately, conflicting data exist on the utility of UKA in SONK. Thus, the purpose of this study was to evaluate functional outcomes and revision rates of UKA in the setting of SONK...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29665717/selective-peripheral-nerve-resection-for-treatment-of-persistent-pain-around-the-knee-joint-after-total-knee-arthroplasty
#11
Guangjun Zhong, Zhu Liang, Jiang Kan, Aikeremujiang Muheremu
Objective This study was performed to determine the efficacy of selective peripheral nerve resection for treatment of persistent neuropathic pain after total knee arthroplasty (TKA). Methods Patients who underwent TKA in our department from January 2013 to July 2016 and experienced persistent pain around the knee joint after TKA were retrospectively included in the current study. Sixty patients were divided into experimental and control groups according the treatment they received. The treatment effect was evaluated by the Hospital for Special Surgery (HSS) knee score and visual analog scale (VAS) pain score preoperatively and at 1, 2, 3, 6, and 12 months postoperatively...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29664877/juvenile-osteochondritis-dissecans-of-the-trochlea-a-cohort-study-of-34-trochlear-lesions-associated-with-sporting-activities-that-load-the-patellofemoral-joint
#12
Meghan J Price, Maria Tuca, Joseph Nguyen, Jason Silberman, Eva Luderowski, Tyler J Uppstrom, Daniel W Green
BACKGROUND: Juvenile osteochondritis dissecans (JOCD) lesions are rarely located in the trochlea and few studies have focused on the causes and outcomes of JOCD lesions in this part of the knee. The purpose of this study is to (1) evaluate the clinical characteristics and outcomes of patients who undergo surgery for JOCD in this unusual location as well as (2) assess the association between trochlear JOCD and participation in sporting activities that load the patellofemoral joint. METHODS: We conducted a retrospective cohort study of 34 trochlear JOCD lesions in 30 patients...
April 16, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29664872/team-approach-the-management-of-infection-after-total-knee-replacement
#13
Chun Hoi Yan, Carla Renata Arciola, Alex Soriano, L Scott Levin, Thomas W Bauer, Javad Parvizi
No abstract text is available yet for this article.
April 17, 2018: JBJS Reviews
https://www.readbyqxmd.com/read/29664871/perioperative-considerations-to-reduce-infection-risk-in-primary-total-hip-and-knee-arthroplasty
#14
Michael J DeRogatis, Annalisse M Mahon, Patrick Lee, Paul S Issack
No abstract text is available yet for this article.
April 17, 2018: JBJS Reviews
https://www.readbyqxmd.com/read/29664339/general-practitioners-referring-adults-to-mr-imaging-for-knee-pain-a-randomized-controlled-trial-to-assess-cost-effectiveness
#15
Kim van Oudenaarde, Nynke M Swart, Johan L Bloem, Sita M A Bierma-Zeinstra, Paul R Algra, Patrick J E Bindels, Bart W Koes, Rob G H H Nelissen, Jan A N Verhaar, Pim A J Luijsterburg, Monique Reijnierse, Wilbert B van den Hout
Purpose To determine the cost-effectiveness of early referral by the general practitioner for magnetic resonance (MR) imaging compared with usual care alone in patients aged 18-45 years with traumatic knee symptoms. Materials and Methods Cost-utility analysis was performed parallel to a prospective multicenter randomized controlled trial in Dutch general practice. A total of 356 patients with traumatic knee symptoms were included from November 2012 to December 2015 (mean age, 33 years ± 8 [standard deviation]; 222 men [62%])...
April 17, 2018: Radiology
https://www.readbyqxmd.com/read/29663650/content-of-distinct-metals-in-periprosthetic-tissues-and-pseudosynovial-joint-fluid-in-patients-with-total-joint-arthroplasty
#16
Martin Kuba, Jiří Gallo, Tomáš Pluháček, Martin Hobza, David Milde
This prospective study examined the content of metals released from total joint arthroplasty into joint fluid, whole blood and periprosthetic tissues. We determined the levels of Ti, V, Nb, Co, Cr, and Mo, using inductively coupled plasma mass spectrometry, in samples from patients who underwent reoperation of total hip or knee arthroplasty. All of the patients (n = 117) included in the study had either metal on polyethylene or ceramic on polyethylene-bearing pairs. First, our results conclusively showed that the majority of released metals were deposited in periprosthetic tissues...
April 16, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29663554/implant-associated-bacterial-biofilm-and-quorum-sensing-in-periprosthetic-joint-infections
#17
Jake A Mooney, Eric M Pridgen, Robert Manasherob, Gina Suh, Helen E Blackwell, Annelise E Barron, Paul L Bollyky, Stuart B Goodman, Derek F Amanatullah
Periprosthetic joint infection (PJI) continues to be a common complication after total knee arthroplasty and total hip arthroplasty leading to severe morbidity and mortality. With an aging population and increasing prevalence of total joint replacement procedures, the burden of PJI will be felt not only by individual patients, but in increased healthcare costs. Current treatment of PJI is inadequate resulting in incredibly high failure rates. This is believed to be largely mediated by the presence of bacterial biofilms...
April 16, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29663192/human-knee-meniscus-regeneration-strategies-a-review-on-recent-advances
#18
REVIEW
Mamatha M Pillai, J Gopinathan, R Selvakumar, Amitava Bhattacharyya
PURPOSE OF REVIEW: Lack of vascularity in the human knee meniscus often leads to surgical removal (total or partial meniscectomy) in the case of severe meniscal damage. However, complete recovery is in question after such removal as the meniscus plays an important role in knee stability. Thus, meniscus tissue regeneration strategies are of intense research interest in recent years. RECENT FINDINGS: The structural complexity and inhomogeneity of the meniscus have been addressed with processing technologies for precisely controlled three dimensional (3D) complex porous scaffold architectures, the use of biomolecules and nanomaterials...
April 16, 2018: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/29663012/medial-joint-line-elevation-of-the-tibia-measured-during-surgery-has-a-significant-correlation-with-the-limb-alignment-changes-following-medial-unicompartmental-knee-arthroplasty
#19
Yuichi Kuroda, Koji Takayama, Kazunari Ishida, Shinya Hayashi, Shingo Hashimoto, Masanori Tsubosaka, Takehiko Matsushita, Takahiro Niikura, Kotaro Nishida, Ryosuke Kuroda, Tomoyuki Matsumoto
PURPOSE: This study aimed to determine the correlation between the change in joint line height calculated from the resected bone and insert thickness during surgery and the change in limb alignment following unicompartmental knee arthroplasty (UKA). It was hypothesized that joint line elevation is correlated with the change in limb alignment. METHODS: A total of 74 consecutive patients diagnosed with either isolated medial compartmental osteoarthritis (38 patients) or spontaneous osteonecrosis of the knee (36 patients) were included...
April 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29662913/high-rate-of-missed-lateral-meniscus-posterior-root-tears-on-preoperative-magnetic-resonance-imaging
#20
Aaron J Krych, Isabella T Wu, Vishal S Desai, Naveen S Murthy, Mark S Collins, Daniel B F Saris, Bruce A Levy, Michael J Stuart
Background: Lateral meniscus posterior root tears (LMPRTs), if left untreated, can cause devastating effects to the knee, with rapid articular cartilage degeneration and loss of the meniscus as a secondary stabilizer. Detection and surgical repair of these defects have been linked to favorable outcomes, but preoperative identification of LMPRTs continues to be challenging. Purpose: To determine the rate of LMPRTs diagnosed preoperatively on magnetic resonance imaging (MRI) in a consecutive series of arthroscopically confirmed LMPRTs...
April 2018: Orthopaedic Journal of Sports Medicine
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