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Chronic urinary obstruction

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https://www.readbyqxmd.com/read/29676622/low-to-moderate-arsenic-exposure-and-respiratory-health-in-american-indian-communities
#1
Martha Powers, Tiffany R Sanchez, Maria Grau-Perez, Fawn Yeh, Kevin Francesconi, Walter Goessler, Christine M George, Christopher Heaney, Lyle G Best, Jason Umans, Robert H Brown, Ana Navas-Acien
RATIONALE: Exposure to inorganic arsenic, through drinking naturally-contaminated water, is an established cause of lung cancer. Evidence on the impact of arsenic exposure on lung function, however, is less conclusive. The evidence available, mostly from populations exposed to water arsenic levels >100 μg/L, suggests that arsenic exposure is associated with lower lung function. Prospective studies and studies examining low-to-moderate levels of water arsenic exposure (<50 μg/L) the level relevant for U...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29662959/quarter-century-management-of-chronic-ureteropelvic-junction-obstruction-in-a-solitary-kidney-with-a-ureteral-stent
#2
Garen Abedi, Roshan M Patel, Cyrus Lin, Ralph V Clayman
Background: The ureteral stent provides a conduit for urinary drainage from the kidney to the bladder and is integral to contemporary urologic practice. A ureteral stent is often utilized in acute conditions to prevent or overcome obstruction; however, in nonsurgical patients, because of disease or preference, a ureteral stent may be used as a last resort for long-term management of a stricture in lieu of a nephrostomy tube. This case highlights a patient whose chronic ureteral obstruction has been managed with an indwelling ureteral stent for 25 years; remarkably, stent exchanges are currently required only every 2 years...
2018: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29644715/comparison-of-biochemical-analysis-of-fetal-serum-and-fetal-urine-in-the-prediction-of-postnatal-renal-outcome-in-lower-urinary-tract-obstruction
#3
Emmanuel Spaggiari, Julien J Stirnemann, Sara Benedetti, Sophie Dreux, Laurent J Salomon, Thomas Blanc, Jonathan Rosenblatt, Romain Favre, Yves Ville, Françoise Muller
OBJECTIVES: To compare the prognostic value of fetal serum biochemistry and fetal urine biochemistry in predicting renal outcome in LUTO. METHODS: We retrospectively studied renal outcome following a prenatal diagnosis of LUTO in cases for which both fetal blood and fetal urine were sampled. We classified the renal outcome as either "favorable", when postnatal renal function was normal, or "adverse", in the case of postnatal chronic renal failure or when renal histological lesions were present at autopsy in the case of termination of pregnancy...
April 12, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29626002/evaluating-off-label-uses-of-acetazolamide
#4
REVIEW
Megan A Van Berkel, Jessica L Elefritz
PURPOSE: Current off-label uses of acetazolamide in hospitalized patients are reviewed. SUMMARY: Acetazolamide is a carbonic anhydrase inhibitor typically used for indications including epilepsy, glaucoma, edema, and altitude sickness but it may be prescribed in hospitalized patients for off-label indications. It inhibits carbonic anhydrase, which leads to reduced hydrogen ion secretion in the proximal renal tubule, resulting in increased bicarbonate and cation excretion and causing urinary alkalization and diuresis...
April 15, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29618675/prevalence-of-escherichia-coli-resistant-to-beta-lactam-antibiotics-among-patients-with-chronic-obstructive-pulmonary-disease-and-urinary-tract-infection
#5
Emilija Nikolić, Tijana Brandmajer, Vesna Bokan, Maria Ulyashova, Maya Rubtsova
Urinary tract infection (UTI), which is typically caused by Escherichia coli (E. coli), is an insufficiently recognized co-morbidity among patients with chronic obstructive pulmonary disease (COPD). Adequate treatment can be complicated by resistance of the causative pathogen to beta-lactam antibiotics, which often produce beta-lactamase enzymes that destroy the antibiotic. The beta-lactamase family of enzymes is extremely diverse, including different types of enzyme and mutant forms. In this study, we analyzed 580 patients with COPD (236 females and 344 males) and thus found 218 patients with co-morbid UTIs, including 58 patients with UTI caused by E...
2018: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29617078/complete-supine-percutaneous-nephrolithotomy-with-gopro%C3%A2-ten-steps-for-success
#6
Fabio Carvalho Vicentini, Hugo Daniel Barone Dos Santos, Carlos Alfredo Batagello, Julia Rothe Amundson, Evaristo Peixoto Oliveira, Giovanni Scala Marchini, Miguel Srougi, Willian Carlos Nahas, Eduardo Mazzucchi
OBJECTIVE: To show a video of a complete supine Percutaneous Nephrolithotomy (csPCNL) performed for the treatment of a staghorn calculus, from the surgeon's point of view. The procedure was recorded with a GoPro® camera, demonstrating the ten essential steps for a successful procedure. MATERIALS AND METHODS: The patient was a 38 years-old woman with 2.4cm of left kidney lower pole stone burden who presented with 3 months of lumbar pain and recurrent urinary tract infections...
March 15, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29615838/spontaneous-perirenal-urinoma-induced-by-nsaid-associated-acute-interstitial-nephritis
#7
Hsiu-Wen Chang, Chia-Hao Kuei, Chin-Feng Tseng, Yi-Chou Hou, Ying-Lan Tseng
Urinoma, defined as the urine leakage beyond the urinary tract, is commonly induced by blunt trauma or urinary tract obstruction by stone, intra-abdominal malignancy, or retroperitoneal fibrosis. Spontaneous urinoma is rare and parenchymal pathologic change is rarely mentioned when urinoma is found. We present a case of a 28-year-old woman with bilateral flank pain induced by spontaneous urinoma. The lady received chronic analgesics because of migraine. After intravenous ketorolac injection, bilateral perirenal urinoma developed...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29608020/prostatic-stromal-inflammation-is-associated-with-bladder-outlet-obstruction-in-patients-with-benign-prostatic-hyperplasia
#8
So Inamura, Hideaki Ito, Tomochika Shinagawa, Manami Tsutsumiuchi, Minekatsu Taga, Motohiro Kobayashi, Osamu Yokoyama
BACKGROUND: Benign prostatic hyperplasia (BPH) is a common urologic disease in older men. Prostatic inflammation research has focused on the magnitude of inflammation; its location has received little attention. We investigated whether the anatomic location of prostatic inflammation is related to the severity of lower urinary tract symptoms (LUTS), measured subjectively and objectively. METHODS: We retrospectively analyzed hematoxylin+eosin-stained tissue specimens from 179 BPH patients who underwent transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HoLEP)...
April 2, 2018: Prostate
https://www.readbyqxmd.com/read/29595914/uromodulin-deficiency-alters-tubular-injury-and-interstitial-inflammation-but-not-fibrosis-in-experimental-obstructive-nephropathy
#9
Olena Maydan, Paul G McDade, Yan Liu, Xue-Ru Wu, Douglas G Matsell, Allison A Eddy
Human GWAS and Mendelian genetic studies have linked polymorphic variants and mutations in the human uromodulin gene (UMOD) with chronic kidney disease. The primary function of this kidney-specific and secreted protein remains elusive. This study investigated whether UMOD deficiency modified responses to unilateral ureteral obstruction (UUO)-induced kidney injury. Kidneys harvested from groups of wild-type (UMOD+/+) and knockout (UMOD-/-) male mice (n = 7-10 each) were studied on days 7, 14, and 21. Compared to sham kidneys, UMOD protein levels increased 9-13x after UUO and were associated with increased urinary UMOD levels...
March 2018: Physiological Reports
https://www.readbyqxmd.com/read/29595706/large-sliding-inguino-scrotal-hernia-of-the-urinary-bladder-a-case-report-and-literature-review
#10
Ping Wang, Yonggang Huang, Jing Ye, Guodong Gao, Fangjie Zhang, Hao Wu
RATIONALE: Sliding inguinal hernias of the urinary bladder are protrusions of the bladder through the internal inguinal ring, most of which are insignificant and diagnosed intra-operatively. Large inguino-scrotal bladder hernias commonly present with lower urinary tract symptoms and may cause severe complications, including bladder incarceration or necrosis, bladder hemorrhage, obstructive or neurogenic bladder dysfunction, and even renal failure. PATIENT CONCERNS: We describe and discuss the clinical findings and management of a 59-year-old man who complained of a decrease in scrotal size after voiding and 2-stage voiding requiring pressure to the scrotum...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29574339/indoor-black-carbon-of-outdoor-origin-and-oxidative-stress-biomarkers-in-patients-with-chronic-obstructive-pulmonary-disease
#11
Stephanie T Grady, Petros Koutrakis, Jaime E Hart, Brent A Coull, Joel Schwartz, Francine Laden, Junfeng Jim Zhang, Jicheng Gong, Marilyn L Moy, Eric Garshick
OBJECTIVES: We assessed relationships between indoor black carbon (BC) exposure and urinary oxidative stress biomarkers, 8-hydroxy-2'-deoxyguanosine (8-OHdG) and malondialdehyde (MDA), in participants with chronic obstructive pulmonary disease (COPD). METHODS: Eighty-two participants completed in-home air sampling for one week prior to providing urine samples up to four times in a year. Weekly indoor and daily outdoor concentrations were used to estimate indoor daily lags and moving averages...
March 22, 2018: Environment International
https://www.readbyqxmd.com/read/29550956/imaging-non-vascular-complications-of-renal-transplantation
#12
Nancy Kim, Roxanna Juarez, Angela D Levy
In patients with end-stage renal disease, the treatment of choice for most patients is renal transplantation. Complications that occur after kidney transplant can be broadly divided into vascular and non-vascular categories. Non-vascular complications can further be divided into surgical and medical categories. When evaluating renal transplant imaging, it is helpful to consider the occurrence of complications in a timeline from time of surgery. Ultrasound is often the first modality used for evaluation of renal transplants particularly in the early postoperative period...
March 17, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29545043/outcomes-of-ureteroscopic-stone-treatment-in-spinal-cord-injury-patients
#13
Duncan R Morhardt, Miriam Hadj-Moussa, He Chang, J Stuart Wolf, William W Roberts, John T Stoffel, Gary J Faerber, Anne P Cameron
OBJECTIVE: To evaluate the association of clinical factors on outcomes in SCI patients undergoing ureteroscopy. Immobility, recurrent urinary tract infection, and lower urinary tract dysfunction contribute to renal stone formation in spinal cord injury (SCI) patients. Ureteroscopy is a commonly utilized treatment modality, however, surgical complication rates and outcomes have been poorly defined. Evidence guiding safe and effective treatment of stones in this cohort remains scarce. METHODS: Records were retrospectively reviewed for SCI patients who underwent ureteroscopy for kidney stones from 1996-2014 at a single institution...
March 12, 2018: Urology
https://www.readbyqxmd.com/read/29532221/pelvic-floor-ultrasound-in-the-diagnosis-of-sling-complications
#14
Lewis Chan, Vincent Tse
PURPOSE: The mid-urethral synthetic sling (MUS) procedure has become the standard of care for treatment of female stress urinary incontinence. However, a small number of patients will have complications following MUS including failure, obstructive voiding, sling erosion, or chronic pain. This paper discusses the role of 2D and 3D ultrasound imaging in the evaluation of the female patient with complications following placement of a synthetic mid-urethral sling. RESULTS: The MUS is easily visualized as an echogenic structure on ultrasound and can be imaged by transperineal, transvaginal and introital approaches...
March 12, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29526792/-urinary-tract-involvement-by-endometriosis-techniques-and-outcomes-of-surgical-management-cngof-has-endometriosis-guidelines
#15
P-A Bolze, P Paparel, F Golfier
Urinary tract involvement by endometriosis is reported in 1% of endometriosis patients (NP3). Consequences range from pelvic pain for bladder localizations to silent kidney loss in case of chronic ureteral obstruction (NP3). The feasibility of laparoscopic management was widely proven (NP3) and may reduce hospital stay length (NP4). Radical surgery with partial cystectomy for bladder localizations was shown to significantly and durably reduce pain symptoms with low risk of a severe postoperative complications (NP3)...
March 8, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29522877/metabonomic-profiling-of-chronic-intermittent-hypoxia-in-a-mouse-model
#16
Stéphanie Conotte, Alexandra Tassin, Raphaël Conotte, Jean-Marie Colet, Karim Zouaoui Boudjeltia, Alexandre Legrand
Chronic intermittent hypoxia (ChIH) is a dominant feature of obstructive sleep apnoea (OSA) and is associated to metabolic alterations and oxidative stress (OS). Although management of OSA is well established, the research of new biomarkers that are independent of confounding factors remains necessary to improve the early detection of comorbidity and therapeutic follow-up. In this study, the urinary metabonomic profile associated to intermittent hypoxia was evaluated in a mouse model. When exposed to intermittent hypoxia, animals showed a significant alteration in energy metabolism towards anaerobic pathways and signs of OS imbalance...
March 6, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29490061/defining-the-appropriateness-and-inappropriateness-of-antibiotic-prescribing-in-primary-care
#17
David R M Smith, F Christiaan K Dolk, Koen B Pouwels, Morag Christie, Julie V Robotham, Timo Smieszek
Objectives: To assess the appropriateness of prescribing systemic antibiotics for different clinical conditions in primary care, and to quantify 'ideal' antibiotic prescribing proportions in conditions for which antibiotic treatment is sometimes but not always indicated. Methods: Prescribing guidelines were consulted to define the appropriateness of antibiotic therapy for the conditions that resulted in antibiotic prescriptions between 2013 and 2015 in The Health Improvement Network (THIN) primary care database...
February 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29490060/actual-versus-ideal-antibiotic-prescribing-for-common-conditions-in-english-primary-care
#18
Koen B Pouwels, F Christiaan K Dolk, David R M Smith, Julie V Robotham, Timo Smieszek
Objectives: Previous work based on guidelines and expert opinion identified 'ideal' prescribing proportions-the overall proportion of consultations that should result in an antibiotic prescription-for common infectious conditions. Here, actual condition-specific prescribing proportions in primary care in England were compared with ideal prescribing proportions identified by experts. Methods: All recorded consultations for common infectious conditions (cough, bronchitis, exacerbations of asthma or chronic obstructive pulmonary disease, sore throat, rhinosinusitis, otitis media, lower respiratory tract infection, upper respiratory tract infection, influenza-like illness, urinary tract infection, impetigo, acne, gastroenteritis) for 2013-15 were extracted from The Health Improvement Network (THIN) database...
February 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29489552/nephrogenic-adenoma-in-the-setting-of-refractory-labial-agglutination-in-an-elderly-woman
#19
Carol Emi Bretschneider, Sarah M Share, Marie Fidela R Paraiso
BACKGROUND: Severe labial agglutination can be refractory to outpatient management and can lead to voiding dysfunction in postmenopausal women. Labial agglutination is often a sequela of long-standing inflammatory processes, which include untreated lichen planus, lichen sclerosus, and atrophic vaginitis. CASE: An 82-year-old parous woman presented with severe labial agglutination and complete obstruction of her vaginal introitus, causing obstructive voiding symptoms...
February 27, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29480882/delayed-diagnosis-of-xanthogranulomatous-pyelonephritis-in-a-quadriplegic-patient-with-uncontrolled-cutaneous-fistula-a-case-report
#20
Jae-Hyuk Yang, Jin Yong Shin, Si-Gyun Roh, Suk-Choo Chang, Nae-Ho Lee
RATIONALE: Xanthogranulomatous pyelonephritis (XGP) is a chronic destructive granulomatous inflammation that is characterized by urinary tract obstruction and invasion of the renal parenchyma. Although rare, XGP can lead to fatal complications, including perinephric inflammation, psoas abscess, and cutaneous fistula. PATIENT CONCERNS: A quadriplegic patient initially presented to the hospital with a chronic open wound and cutaneous fistula. DIAGNOSES: Abdominal computed tomography revealed a renal obstructing stone and enlarged right kidney with a perinephric fluid collection that communicated with the cutaneous fistula...
January 2018: Medicine (Baltimore)
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