keyword
MENU ▼
Read by QxMD icon Read
search

00&9

keyword
https://www.readbyqxmd.com/read/29345859/development-of-a-risk-prediction-model-for-lung-cancer-the-japan-public-health-center-based-prospective-study
#1
Hadrien Charvat, Shizuka Sasazuki, Taichi Shimazu, Sanjeev Budhathoki, Manami Inoue, Motoki Iwasaki, Norie Sawada, Taiki Yamaji, Shoichiro Tsugane
While the impact of tobacco consumption on the occurrence of lung cancer is well-established, risk estimation could be improved by risk prediction models that consider various smoking habits, such as quantity, duration, and time since quitting. We constructed a risk prediction model using a population of 59,161 individuals from JPHC Study Cohort II. A parametric survival model was used to assess the impact of age, gender and smoking-related factors (cumulative smoking intensity measured in pack-years, age at initiation, and time since cessation)...
January 18, 2018: Cancer Science
https://www.readbyqxmd.com/read/29345609/dietary-patterns-and-their-association-with-adiponectin-and-leptin-concentrations-throughout-pregnancy-a-prospective-cohort
#2
Nadya H Alves-Santos, Paula G Cocate, Ilana Eshriqui, Camila Benaim, Érica G Barros, Pauline M Emmett, Gilberto Kac
The aim of this study was to evaluate the association of dietary patterns (DP) with maternal adiposity indicators, leptin, adiponectin and insulin concentrations during pregnancy. A prospective cohort of pregnant women followed up at the 5th-13th, 20th -26th and 30th-36th gestational weeks and 30-40 d postpartum was conducted in Rio de Janeiro. A FFQ was administered in the third trimester (30th-36th gestational weeks). The reduced rank regression procedure was used to identify DP that explain response variables (dietary fibre and total fat) related to indicators of maternal adiposity (postpartum weight retention and gestational weight gain (GWG) adequacy), and plasma leptin, adiponectin and insulin concentrations...
January 18, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29344232/novel-combination-of-paraspinal-keyhole-surgery-with-a-tubular-retractor-system-leads-to-significant-improvements-in-lumbar-intraspinal-extramedullary-schwannomas
#3
Yuandong Zhuang, Gangfeng Cai, Chaofeng Fu, Weiqiang Zhang, Wei Zhao, Rui Wang, Chunhua Wang, Songsheng Shi, Chunmei Chen
The aim of the present study was to investigate the efficacy of combining paraspinal keyhole surgery with a tubular retractor system for the microsurgical removal of lumbar intraspinal extramedullary schwannomas. A retrospective analysis was conducted of 56 patients with lumbar intraspinal extramedullary schwannomas who were treated using the microsurgical paraspinal keyhole approach with a tubular retractor system. The mean ± standard deviation was calculated for the following parameters: Surgery time (96...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29344138/clinical-and-genetic-analysis-of-tuberous-sclerosis-complex-associated-renal-angiomyolipoma-in-chinese-pedigrees
#4
Shuqiang Li, Yushi Zhang, Jinxing Wei, Xuepei Zhang
Tuberous sclerosis complex-associated renal angiomyolipoma (TSC-RAML) confers a high risk of bleeding and even mortality. However, data on TSC-RAML in Chinese pedigrees is extremely lacking. The present study aimed to investigate its clinical and genetic characteristics by obtaining a detailed medical history from 6 probands and their family members, and reassessing blood tests, computed tomography and renal dynamic imaging examinations that were conducted in the TSC-RAML patients. The TSC1/TSC2 mutation was detected in 2 families...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29343517/early-infant-diet-and-islet-autoimmunity-in-the-teddy-study
#5
Ulla Uusitalo, Hye-Seung Lee, Carin Andrén Aronsson, Kendra Vehik, Jimin Yang, Sandra Hummel, Katherine Silvis, Åke Lernmark, Marian Rewers, William Hagopian, Jin-Xiong She, Olli Simell, Jorma Toppari, Anette-G Ziegler, Beena Akolkar, Jeffrey Krischer, Suvi M Virtanen, Jill M Norris
OBJECTIVE: To examine duration of breastfeeding and timing of complementary foods and risk of islet autoimmunity (IA). RESEARCH DESIGN AND METHODS: The TEDDY study prospectively follows 8,676 children with increased genetic risk of type 1 diabetes (T1D) in the U.S., Finland, Germany, and Sweden. This study included 7,563 children with at least 9 months of follow-up. Blood samples were collected every 3 months from birth to evaluate IA, defined as persistent, confirmed positive insulin autoantibodies (IAAs), glutamic acid decarboxylase, or insulinoma antigen-2...
January 17, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29343224/development-and-validation-of-self-reported-line-drawings-of-the-modified-beighton-score-for-the-assessment-of-generalised-joint-hypermobility
#6
Dale J Cooper, Brigitte E Scammell, Mark E Batt, Debbie Palmer
BACKGROUND: The impracticalities and comparative expense of carrying out a clinical assessment is an obstacle in many large epidemiological studies. The purpose of this study was to develop and validate a series of electronic self-reported line drawing instruments based on the modified Beighton scoring system for the assessment of self-reported generalised joint hypermobility. METHODS: Five sets of line drawings were created to depict the 9-point Beighton score criteria...
January 17, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29342310/temporal-trends-of-sources-of-cigarettes-among-u-s-high-school-students-2001-2015
#7
Hongying Dai, Jianqiang Hao
Introduction: Restricting the supply of cigarettes to youth plays an important role in reducing youth smoking. Methods: The study included data from 8 years of the national Youth Risk Behavior Survey (YRBS) from 2001 to 2015 with 99,572 high school students less than 18 years old. Data were weighted to provide national estimates of the temporal trends of cigarette sources. Each cigarette source was analyzed by a separate multivariable logistic regression model and the linear trend odds ratio (aOR) was adjusted by age, sex, race/ethnicity, and smoking frequency...
January 12, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29342269/a-silent-epidemic-the-prevalence-incidence-and-persistence-of-mycoplasma-genitalium-among-young-asymptomatic-high-risk-women-in-the-united-states
#8
Arlene C Seña, Jeannette Y Lee, Jane Schwebke, Susan S Philip, Harold C Wiesenfeld, Anne M Rompalo, Robert L Cook, Marcia M Hobbs
Background: Mycoplasma genitalium (MG) is a sexually transmitted infection (STI) that can result in pelvic inflammatory disease and adverse pregnancy outcomes. We analyzed data collected from a prospective study of asymptomatic bacterial vaginosis (BV) to determine the natural history of MG. Methods: Women aged 15-25 years, with ≥2 STI risk factors and asymptomatic BV were recruited from 10 sites throughout the United States. Vaginal swabs were collected at enrollment, and by home-based testing every 2 months over 12 months...
January 12, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29342256/comparison-of-pregnancy-outcomes-between-maternity-waiting-home-users-and-non-users-at-hospitals-with-and-without-a-maternity-waiting-home-retrospective-cohort-study
#9
Floris Braat, Tienke Vermeiden, Gashaw Getnet, Rita Schiffer, Thomas van den Akker, Jelle Stekelenburg
Objective: To examine the impact of a maternity waiting home (MWH) by comparing pregnancy outcomes between users and non-users at hospitals with and without an MWH. Methods: We conducted a retrospective cohort study in Ethiopia comparing one hospital with an MWH (Attat) to a second hospital without one (Butajira). A structured questionnaire among sampled women in 2014 and hospital records from 2011 to 2014 were used to compare sociodemographic characteristics and pregnancy outcomes between Attat MWH users and non-MWH users, Attat MWH users and Butajira, and Attat non-MWH users and Butajira...
January 12, 2018: International Health
https://www.readbyqxmd.com/read/29341488/gene-gene-interaction-between-msx1-and-tp63-in-asian-case-parent-trios-with-nonsyndromic-cleft-lip-with-or-without-cleft-palate
#10
Dongjing Liu, Holger Schwender, Mengying Wang, Hong Wang, Ping Wang, Hongping Zhu, Zhibo Zhou, Jing Li, Tao Wu, Terri H Beaty
BACKGROUND: Small ubiquitin-like modification, also known as sumoylation, is a crucial post-translational regulatory mechanisms involved in development of the lip and palate. Recent studies reported two sumoylation target genes, MSX1 and TP63, to have achieved genome-wide level significance in tests of association with nonsyndromic clefts. Here, we performed a candidate gene analysis considering gene-gene and gene-environment interaction for SUMO1, MSX1, and TP63 to further explore the etiology of nonsyndromic cleft lip with or without cleft palate (NSCL/P)...
January 17, 2018: Birth Defects Research
https://www.readbyqxmd.com/read/29341060/rationale-of-decreasing-low-density-lipoprotein-cholesterol-below-70-mg-dl-in-patients-with-coronary-artery-disease-a-retrospective-virtual-histology-intravascular-ultrasound-study
#11
Young Hoon Seo, Duck-Jun Seo, In Geol Song, Ki-Hong Kim, Taek-Geun Kwon, Jang-Ho Bae
BACKGROUND: The associations between statin and coronary plaque compositional changes were reported according to the use of high dose or not. An evaluation of the impact of low-density lipoprotein cholesterol (LDL-C) < 70 mg/dL by using real world dosages of statin on coronary plaque composition was undertaken. METHODS: The study subjects consisted of 61 patients (mean 59.9 years old, 45 males) who underwent percutaneous coronary intervention, baseline and follow-up (F/U; mean 8...
January 17, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29340590/efficacy-and-safety-of-deep-brain-stimulation-in-tourette-syndrome-the-international-tourette-syndrome-deep-brain-stimulation-public-database-and-registry
#12
Daniel Martinez-Ramirez, Joohi Jimenez-Shahed, James Frederick Leckman, Mauro Porta, Domenico Servello, Fan-Gang Meng, Jens Kuhn, Daniel Huys, Juan Carlos Baldermann, Thomas Foltynie, Marwan I Hariz, Eileen M Joyce, Ludvic Zrinzo, Zinovia Kefalopoulou, Peter Silburn, Terry Coyne, Alon Y Mogilner, Michael H Pourfar, Suketu M Khandhar, Man Auyeung, Jill Louise Ostrem, Veerle Visser-Vandewalle, Marie-Laure Welter, Luc Mallet, Carine Karachi, Jean Luc Houeto, Bryan Timothy Klassen, Linda Ackermans, Takanobu Kaido, Yasin Temel, Robert E Gross, Harrison C Walker, Andres M Lozano, Benjamin L Walter, Zoltan Mari, William S Anderson, Barbara Kelly Changizi, Elena Moro, Sarah Elizabeth Zauber, Lauren E Schrock, Jian-Guo Zhang, Wei Hu, Kyle Rizer, Erin H Monari, Kelly D Foote, Irene A Malaty, Wissam Deeb, Aysegul Gunduz, Michael S Okun
Importance: Collective evidence has strongly suggested that deep brain stimulation (DBS) is a promising therapy for Tourette syndrome. Objective: To assess the efficacy and safety of DBS in a multinational cohort of patients with Tourette syndrome. Design, Setting, and Participants: The prospective International Deep Brain Stimulation Database and Registry included 185 patients with medically refractory Tourette syndrome who underwent DBS implantation from January 1, 2012, to December 31, 2016, at 31 institutions in 10 countries worldwide...
January 16, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29339564/accuracy-of-the-urinalysis-for-urinary-tract-infections-in-febrile-infants-60-days-and-younger
#13
Leah Tzimenatos, Prashant Mahajan, Peter S Dayan, Melissa Vitale, James G Linakis, Stephen Blumberg, Dominic Borgialli, Richard M Ruddy, John Van Buren, Octavio Ramilo, Nathan Kuppermann
OBJECTIVES: Reports of the test accuracy of the urinalysis for diagnosing urinary tract infections (UTIs) in young febrile infants have been variable. We evaluated the test characteristics of the urinalysis for diagnosing UTIs, with and without associated bacteremia, in young febrile infants. METHODS: We performed a planned secondary analysis of data from a prospective study of febrile infants ≤60 days old at 26 emergency departments in the Pediatric Emergency Care Applied Research Network...
January 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29338081/nonsurgical-premature-menopause-and-reproductive-implications-in-survivors-of-childhood-cancer-a-report-from-the-childhood-cancer-survivor-study
#14
Jennifer M Levine, John A Whitton, Jill P Ginsberg, Daniel M Green, Wendy M Leisenring, Marilyn Stovall, Leslie L Robison, Gregory T Armstrong, Charles A Sklar
BACKGROUND: Survivors of childhood cancer are at risk of nonsurgical premature menopause (NSPM). To the authors' knowledge, risk factors for NSPM and its impact on reproduction remain poorly defined. METHODS: The menopausal status of 2930 survivors diagnosed between 1970 and 1986 (median age, 6 years [range, birth-20 years]) who were aged > 18 years at the time of the current study (median age, 35 years [range, 18-58 years]) was compared with 1399 siblings...
January 16, 2018: Cancer
https://www.readbyqxmd.com/read/29338038/does-the-leading-pharmaceutical-reform-in-china-really-solve-the-issue-of-overly-expensive-healthcare-services-evidence-from-an-empirical-study
#15
Yunzhen He, Guanshen Dou, Qiaoyun Huang, Xinyu Zhang, Yingfeng Ye, Mengcen Qian, Xiaohua Ying
BACKGROUND: Healthcare system reform of Sanming city has become a leading healthcare reform model in China. It has developed a rigorous pharmaceutical reform consisted of the Zero Mark-up Drug Policy and the Centralized Procurement of Medicine Policy to bring down drug expenses and total health expenditures. However, despite the credit and much attention have been given to Sanming's pharmaceutical reform, its impact still remains unclear. Therefore, the purpose of this study was to explore the impact of the pharmaceutical reform of Sanming on both drug and total health expenditures...
2018: PloS One
https://www.readbyqxmd.com/read/29337671/spectrophotometric-method-for-simultaneous-determination-of-valsartan-and-substances-from-the-group-of-statins-in-binary-mixtures
#16
Mariusz Stolarczyk, Anna Apola, Anna Maślanka, Anna Kwiecień, Włodzimierz Opoka
Applicability of derivative spectrophotometry for the determination of valsartan in the presence of a substance from the group of statins was checked. The obtained results indicate that the proposed method may be effective by using appropriate derivatives: for valsartan and fluvastatin - D1, D2 and D3, for valsartan and pravastatin - D1 and D3, for valsartan and atorvastatin - D2 and D3. The method was characterized by high sensitivity and accuracy. Linearity was maintained in the following ranges: 9.28-32...
December 20, 2017: Acta Pharmaceutica
https://www.readbyqxmd.com/read/29337039/the-presence-of-small-and-diminutive-proximal-hyperplastic-polyps-is-associated-with-higher-rates-of-synchronous-advanced-neoplasia-compared-with-patients-without-serrated-lesions
#17
Hamoudah Thayer, Ma Karen, Esteban Marcus, Hayat Waqas, Mahon Brett, Jakate Shriram, Melson Joshua
BACKGROUND: The association of proximal small and diminutive hyperplastic polyps (HPs) with synchronous neoplasia (AN) is not well defined. However, sessile serrated polyps, even when small, are known to portend synchronous neoplastic risk. Currently, when proximal small hyperplastic polyps are detected, the USMTF does not recommend a change in surveillance interval. We aimed to compare the rates of synchronous AN in a screening colonoscopy cohort of patients with small and then diminutive proximal HPs in comparison, first to a cohort absent any serrated or proximal hyperplastic polyps, and then in comparison with a cohort with small proximal sessile serrated polyps (SSPs)...
January 11, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29337015/improved-quantitative-fatty-acid-values-with-correction-of-t2-relaxation-time-in-terminal-methyl-group-in-vivo-proton-magnetic-resonance-spectroscopy-at-ultra-high-field-in-hepatic-steatosis
#18
Kyu-Ho Song, Min-Young Lee, Chi-Hyeon Yoo, Song-I Lim, Bo-Young Choe
Proton magnetic resonance spectroscopy (MRS) with optimized relaxation time is an effective method to quantify hepatic fatty acid values and characterize steatosis. The aim of this study is to quantify the difference in hepatic lipid content with metabolic changes during the progression of steatosis by using localized MRS sequence with T2 relaxation time determination. Fatty liver disease was induced in C57BL/6N mice through a high-fat diet (HFD) of pellets containing 60% fat, 20% protein, and 20% carbohydrates...
January 11, 2018: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/29335899/the-ultrasonographic-whirlpool-sign-in-testicular-torsion-valuable-tool-or-waste-of-valuable-time-a-systematic-review-and-meta-analysis
#19
Jared McDowall, Ahmed Adam, Louis Gerber, Callistus O A Enyuma, Sunday J Aigbodion, Sean Buchanan, Abdullah E Laher
PURPOSE: A positive whirlpool sign (WS) is defined as the presence of a spiral-like pattern when the spermatic cord is assessed during ultrasonography (US), using standard, high-resolution ultrasonography (HRUS) and/or color Doppler sonography (CDS), in the presence of testicular torsion. The objective of this review was to assess the validity and accuracy of this sign by performing a comprehensive systematic literature review and meta-analysis. METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, a comprehensive literature search was performed (August, 2017), using the following databases: BMJ Best Practice, Cochrane Library, Embase, PubMed, Scopus, and Web of Science...
January 15, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29335063/tea-consumption-is-associated-with-increased-risk-of-kidney-stones-in-northern-chinese-a-cross-sectional-study
#20
Zhong Biao Wu, Tian Jiang, Guo Bing Lin, You Xin Wang, Yong Zhou, Zhen Qian Chen, Yong Ming Xu, Hai Bo Ye, Bo Jun Chen, Xiao Zhao Bao, Cun Ming Zhang
Kidney stones are a common urinary system condition that can progress to kidney disease. Previous studies on the association between tea consumption and kidney stones are inconsistent. A cross-sectional study to investigate the association between tea consumption and kidney stones was conducted from 2013 to 2014 and recruited 9,078 northern Chinese adults. A total of 8,807 participants were included in the final analysis. Participants' prevalence of kidney stones was 1.07%, 1.73%, and 2.25% based on their tea consumption frequency of never, occasionally, and often groups, respectively...
December 2017: Biomedical and Environmental Sciences: BES
keyword
keyword
2503
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"