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https://www.readbyqxmd.com/read/28808903/clinical-outcomes-of-aortic-repair-in-young-adult-patients-with-acta2-mutations
#1
Yoshimasa Seike, Kenji Minatoya, Hiroaki Sasaki, Hiroshi Tanaka, Tatsuya Itonaga, Yosuke Inoue, Hiroko Morisaki, Takayuki Morisaki, Hatsue Ishibashi-Ueda, Junjiro Kobayashi
OBJECTIVES: Actin, alpha-2, smooth muscle, aorta (ACTA2) mutations are one of the major causes of familial thoracic aortic aneurysms and dissections. The aim of this study was to review our clinical results of young adult patients with aortic disease caused by ACTA2 mutations. METHODS: We reviewed the medical records of 251 patients (<50 years old) who underwent surgery for thoracic aortic diseases between 2004 and 2014. Among them, nine patients (3.5%) had ACTA2 mutations...
August 14, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28808474/effect-of-shin-iseihaito-xinyiqingfeitang-on-acute-streptococcus-pneumoniae-murine-sinusitis-via-macrophage-activation
#2
Masaaki Minami, Toru Konishi, Hiroshi Takase, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Streptococcus pneumoniae (S. pneumoniae) causes sinusitis. The general treatment of S. pneumonia sinusitis is by using antibiotics; however, one of their serious problems is the attenuation of their effect. Shin'iseihaito (Xinyiqingfeitang), a formula of Japanese traditional Kampo medicine, has been used for the treatment of sinusitis in Japan. In this study, we investigated the efficacy of Shin'iseihaito against S. pneumoniae-caused sinusitis in mice. Oral administration of Shin'iseihaito extract (SSHT) decreased the nasal colonization of S...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28801828/a%C3%A2-new-classification-system-is-helpful-in-diagnosing-intracranial-complications-of-acute-mastoiditis-in-ct
#3
R Saat, G Kurdo, N Brandstack, A Laulajainen-Hongisto, J Jero, A Markkola
PURPOSE: To assess the usefulness of the new computed tomography (CT) classification criteria proposed by Horowitz et al. and their effect on inter-observer agreement when estimating intracranial complications of acute mastoiditis. METHODS: In this study 53 contrast-enhanced CT scans of patients with acute mastoiditis were each retrospectively reviewed by two radiologists, using two different assessment criteria for intracranial complications. According to the new criteria, intracranial CT findings in the perisinuous area were graded into four classes (I normal, II linear halo, III nodular halo ≤4 mm thick and IV nodular halo >4 mm thick), where classes III and IV indicate a high risk for epidural abscesses...
August 11, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28800746/artery-of-percheron-infarction-a-case-report
#4
Axel Sandvig, Sandra Lundberg, Jiri Neuwirth
BACKGROUND: The artery of Percheron is a rare anatomic variant of arterial supply to the paramedian thalamus and rostral midbrain, and occlusion of the artery of Percheron results in bilateral paramedian thalamic infarcts with or without midbrain involvement. Acute artery of Percheron infarcts represent 0.1 to 2% of total ischemic stroke. However, of thalamic strokes, occlusion of artery of Percheron is the cause in 4 to 35% of cases. Early diagnosis of artery of Percheron infarction can be challenging because it is infrequent and early computed tomography or magnetic resonance imaging may be negative...
August 12, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28799861/absence-of-cortical-vein-opacification-is-associated-with-lack-of-intra-arterial-therapy-benefit-in-stroke
#5
Ivo G H Jansen, Annemieke B van Vuuren, Wim H van Zwam, Ido R van den Wijngaard, Olvert A Berkhemer, Hester F Lingsma, Cornelis H Slump, Robert J van Oostenbrugge, Kilian M Treurniet, Diederik W J Dippel, Marianne A A van Walderveen, Aad van der Lugt, Yvo B W E M Roos, Henk A Marquering, Charles B L M Majoie, René van den Berg
Purpose To assess the degree of cortical vein opacification in patients with internal carotid artery or middle cerebral artery (MCA) stroke and to evaluate the relationship with treatment benefit from intra-arterial therapy (IAT). Materials and Methods Written informed consent was obtained from all patients in the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands. From the trial's database, all patients (recruited from December 2010 until March 2014) with baseline computed tomographic (CT) angiograms were retrospectively included...
August 11, 2017: Radiology
https://www.readbyqxmd.com/read/28791184/acute-myocardial-infarction-caused-by-an-anomalous-right-coronary-artery-occlusion-presenting-with-precordial-st-elevation
#6
Bruno da Silva Matte, Alexandre Damiani Azmus
Acute coronary syndrome with precordial ST segment elevation is usually related to left anterior descending artery occlusion, although isolated right ventricular infarction has been described as a cause of ST elevation in V1-V3 leads. We present a case of a patient with previous inferior wall infarction and new acute ST elevation myocardial infarction (STEMI) due to proximal right coronary thrombotic occlusion resulting in right ventricular infarction with precordial ST elevation and sinus node dysfunction...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28780656/hus-induced-cardiac-and-circulatory-failure-is-reversible-using-cardiopulmonary-bypass-as-rescue
#7
René F Andersen, Jesper V Bjerre, Johan V Povlsen, Mette Veien, Konstantinos Kamperis, Søren Rittig
BACKGROUND: Extra-renal involvement in hemolytic uremic syndrome (HUS) includes gastrointestinal, pancreatic, hepatic, neurological and cardiac manifestations. The current 3-5% mortality rate in HUS patients is primarily attributed to complications related to the central nervous system and the heart. In this brief report, we illustrate that severe cardiac involvement in a patient with HUS is potentially reversible using cardiopulmonary bypass as rescue. CASE-DIAGNOSIS/TREATMENT: A 12-year-old boy was diagnosed with enterohemorrhagic Escherichia coli-induced HUS related to E...
August 5, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28768452/aetiology-and-clinical-features-of-facial-cellulitis-a-prospective-study
#8
Eivind Rath, Steinar Skrede, Haima Mylvaganam, Trond Bruun
BACKGROUND: In the early 20th century, the face was the predominant site of cellulitis. Despite a relative decrease in the incidence of facial cellulitis, it is still common. There are few studies on this condition during the last decades. The aim of this study was to describe contemporary aetiological and clinical characteristics of patients admitted to hospital with non-suppurative facial cellulitis. METHODS: Patients were included prospectively. Clinical details, comorbidities and biochemistry results were recorded...
August 2, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28762898/a-score-for-paroxysmal-atrial-fibrillation-in-acute-ischemic-stroke
#9
Halvor Naess, Ulrike W Andreassen, Lars Thomassen, Christopher E Kvistad
Aim Many patients with ischemic stroke have paroxysmal atrial fibrillation that may be difficult to detect. We sought to identify markers of paroxysmal atrial fibrillation and construct a score that may help the clinician to select patients for anticoagulation even if investigations do not disclose atrial fibrillation. Methods A group of patients with acute ischemic stroke and TIA and documented paroxysmal atrial fibrillation was compared to a group of patients with ischemic stroke and TIA and no known paroxysmal atrial fibrillation and sinus rhythm on Holter monitoring...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28760211/implantable-cardiac-monitors-in-high-risk-post-infarction-patients-with-cardiac-autonomic-dysfunction-and-moderately-reduced-left-ventricular-ejection-fraction-design-and-rationale-of-the-smart-mi-trial
#10
Wolfgang Hamm, Konstantinos D Rizas, Lukas von Stülpnagel, Nikolay Vdovin, Steffen Massberg, Stefan Kääb, Axel Bauer
BACKGROUND: Most deaths after myocardial infarction (MI) occur in patients with left ventricular ejection fraction (LVEF) >35%, for whom no specific prophylactic strategies exist. Deceleration capacity (DC) of heart rate and periodic repolarization dynamics (PRD) are noninvasive electrophysiological markers depending on the vagal and sympathetic tone. The combination of abnormal DC and/or PRD identifies a new high-risk group among postinfarction patients with LVEF 36%-50%. This new high-risk group has similar characteristics with respect to prognosis and patient numbers to those of the established high-risk group identified by LVEF ≤ 35%...
August 2017: American Heart Journal
https://www.readbyqxmd.com/read/28757765/pulseless-electrical-activity-in-acute-massive-pulmonary-embolism-during-thrombolytic-therapy
#11
Han-Hua Yu, Jing-Ren Jeng
We report a case of acute pulmonary embolism with hemodynamic instability diagnosed by a computed tomography pulmonary angiogram. The patient developed pulseless electrical activity during systemic thrombolytic therapy with recombinant tissue plasminogen activator. Successful return of spontaneous circulation was achieved after immediate cardiopulmonary resuscitation with chest compressions for 6 min. His electrocardiogram (ECG) on arrival in the emergency department displayed sinus tachycardia, an S wave in lead I, a Q wave in lead III, incomplete right bundle branch block (RBBB), T-wave inversion (TWI) in leads V1-V3, ST elevation in leads aVR and V1, and ST depression in leads I, II, III, aVF, and V4-V6...
January 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28756476/development-of-pyriform-sinus-suctioning-programs-for-aspiration-pneumonia-prevention-during-the-acute-stroke
#12
Yuki Inui, Yayoi Kamakura, Junko Fukada, Masahiko Yoneda, Emiko Kataoka, Yasuko Usami, Miki Sugiura, Tetsuya Nagatani, Yukio Seki, Norikazu Hatano, Keizo Yasui
Aspiration due to dysphagia is a factor associated with pneumonia during acute stroke. In such cases, it is likely that secretions in the pyriform sinuses enter the laryngeal inlet. The present study was based on the idea that it is possible to reduce aspiration pneumonia by periodically suctioning and removing such secretions (pyriform sinus suctioning), a study was conducted in a single facility. The incidence of pneumonia as a dependent variable was compared between before (control) and after (intervention group) intervention with pyriform sinus suctioning as an independent variable...
July 29, 2017: Dysphagia
https://www.readbyqxmd.com/read/28751432/severe-hypokalaemia-as-a-cause-of-acute-transient-quadriparesis
#13
Martin Bell Lybecker, Henrik Bjørnsgaard Madsen, Jens Meldgaard Bruun
Hypokalaemic paralysis covers a heterogeneous group of disorders caused either by an enhanced shift of potassium into the cells or following a significant renal or gastrointestinal loss of potassium. We present the case of a 48-year-old Caucasian man with paralysis of both upper and lower extremities. ECG showed sinus rhythm and characteristic changes of hypokalaemia with depression of the ST segment, prolonged QTc interval of 581ms and U waves seen as a small positive deflection at the T wave in the middle precordial leads...
July 27, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28751164/coronary-serum-obtained-after-myocardial-infarction-induces-angiogenesis-and-microvascular-obstruction-repair-role-of-hypoxia-inducible-factor-1a
#14
César Ríos-Navarro, Luisa Hueso, Gema Miñana, Julio Núñez, Amparo Ruiz-Saurí, María Jesús Sanz, Joaquin Cànoves, Francisco J Chorro, Laura Piqueras, Vicente Bodí
INTRODUCTION AND OBJECTIVES: Microvascular obstruction (MVO) exerts deleterious effects following acute myocardial infarction (AMI). We investigated coronary angiogenesis induced by coronary serum and the role of hypoxia-inducible factor-1A (HIF-1A) in MVO repair. METHODS: Myocardial infarction was induced in swine by transitory 90-minute coronary occlusion. The pigs were divided into a control group and 4 AMI groups: no reperfusion, 1minute, 1 week and 1 month after reperfusion...
July 24, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28747025/platelet-function-and-microparticle-levels-in-atrial-fibrillation-changes-during-the-acute-episode
#15
Line Pourtau, Jean Marc Sellal, Romaric Lacroix, Philippe Poncelet, Olivier Bernus, Gisèle Clofent-Sanchez, Mélèze Hocini, Michel Haïssaguerre, Françoise Dignat-George, Frédéric Sacher, Paquita Nurden
BACKGROUND: Thrombotic risk constitutes a major complication of atrial fibrillation (AF). Platelets and microparticles (MPs) are important for hemostasis and thrombosis, however their participation during AF is not well known. The aim of this study was to characterize platelet function and MPs procoagulant and fibrinolytic activity in AF patients and to determine the effects of an acute-AF episode. METHODS: Blood was collected from paroxysmal (21) and persistent (16) AF patients referred for AF catheter ablation...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28744872/antibiotic-prescription-for-endodontic-infections-a-survey-of-brazilian-endodontists
#16
M R Bolfoni, F G Pappen, T Pereira-Cenci, R C Jacinto
AIM: To investigate antibiotic prescribing habits reported by Brazilian Endodontists in specific clinical situations. METHODOLOGY: Brazilian endodontists (n=13,853) were invited to answer an on-line questionnaire. The questionnaire consisted of two parts: the first part contained personal data such as age, gender, years of experience and location of endodontic practice; the second part included questions regarding dentists' behavior when prescribing antibiotics in dental practice...
July 26, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28744321/an-18-f-positron-emitting-fluorescent-cerebrospinal-fluid-probe-for-imaging-damage-to-the-brain-and-spine
#17
Harikrishna Kommidi, Hua Guo, Nandi Chen, Dohyun Kim, Bin He, Amy P Wu, Omer Aras, Richard Ting
Fluorescein is modified to bear (18)F so that it can act as both a positron emitter, and a fluorophore, allowing detection by positron emission tomography (PET), scintillation, and fluorescent imaging (FL). [(18)F]-2 is injected into the intrathecal space of rats and used to observe the cerebrospinal fluid (CSF) that bathes the brain and spine. Injury in three different applications is visualized with [(18)F]-2: 1) detection of a 0.7 mm paranasal-sinus CSF leak (CSFL); 2) detection of 0.5 mm puncture damage to the thoracic spine (acute spinal cord injury); and 3) detection of intracerebral hemorrhage/edema because of traumatic brain injury...
2017: Theranostics
https://www.readbyqxmd.com/read/28736709/spatiotemporal-characterization-of-the-transition-from-sinus-rhythm-to-ventricular-fibrillation-during-an-acute-ischemic-event-in-the-intact-human-heart-by-whole-heart-sock-mapping
#18
Michele Orini, Peter Taggart, Martin Hayward, Pier D Lambiase
No abstract text is available yet for this article.
May 2017: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/28734850/progression-and-reversibility-of-stretch-induced-atrial-remodeling-characterization-and-clinical-implications
#19
REVIEW
Shivshankar Thanigaimani, Emma McLennan, Dominik Linz, Rajiv Mahajan, Thomas A Agbaedeng, Geoffrey Lee, Jonathan M Kalman, Prashanthan Sanders, Dennis H Lau
Atrial fibrillation (AF) is the most common sustained arrhythmia and across the developed nations, it contributes to increasing hospitalizations and healthcare burden. Several comorbidities and risk factors including hypertension, heart failure, obstructive sleep apnoea and obesity are known to play an important role in the initiation and perpetuation of AF and atrial stretch or dilatation may play a central mechanistic role. The impact of atrial stretch in the development of AF can vary dependent on the underlying disease...
July 19, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28731388/electronic-visits-for-minor-acute-illnesses-analysis-of-patient-demographics-prescription-rates-and-follow-up-care-within-an-asynchronous-text-based-online-visit
#20
Kristine S Penza, Martha A Murray, Jennifer L Pecina, Jane F Myers, Joseph W Furst
INTRODUCTION: Patients can obtain medical advice and treatment from a healthcare provider asynchronously through an electronic visit (eVisit) within a secure online portal. METHODS: We conducted a retrospective record review of Mayo Clinic Rochester primary care empaneled patients who had an eVisit for a minor acute illness and were reviewed for 30-day outcomes of follow-up. RESULTS: Of the 1,009 eVisits analyzed, a total of 340 (34%) had follow-up within 30 days, with a follow-up rate of 154 (20%) when those who were advised to follow-up were excluded...
July 20, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
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