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Indirect restorations

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https://www.readbyqxmd.com/read/29149746/habitat-mosaics-and-path-analysis-can-improve-biological-conservation-of-aquatic-biodiversity-in-ecosystems-with-low-head-dams
#1
Sean M Hitchman, Martha E Mather, Joseph M Smith, Jane S Fencl
Conserving native biodiversity depends on restoring functional habitats in the face of human-induced disturbances. Low-head dams are a ubiquitous human impact that degrades aquatic ecosystems worldwide. To improve our understanding of how low-head dams impact habitat and associated biodiversity, our research examined complex interactions among three spheres of the total environment. i.e., how low-head dams (anthroposphere) affect aquatic habitat (hydrosphere), and native biodiversity (biosphere) in streams and rivers...
November 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29145527/evaluation-of-operating-time-and-patient-perception-using-conventional-impression-taking-and-intraoral-scanning-for-crown-manufacture-a-split-mouth-randomized-clinical-study
#2
Yasser Haddadi, Golnosh Bahrami, Flemming Isidor
PURPOSE: To compare operating time and patient perception of conventional impression (CI) taking and intraoral scanning (IOS) for manufacture of a tooth-supported crown. MATERIALS AND METHODS: A total of 19 patients needing indirect full-coverage restorations fitting the requirements for a split-mouth design were recruited. Each patient received two lithium disilicate crowns, one manufactured from CI taking and one from IOS. Both teeth were prepared following the manufacturers' recommendations...
November 16, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29128128/cad-fe-modeling-and-analysis-of-class-ii-restorations-incorporating-resin-composite-glass-ionomer-and-glass-ceramic-materials
#3
Pietro Ausiello, Stefano Ciaramella, Massimo Martorelli, Antonio Lanzotti, Antonio Gloria, David C Watts
OBJECTIVES: To investigate the influence of specific resin-composite, glass ceramic and glass ionomer cement (GIC) material combinations in a "multi-layer" technique to replace enamel and dentin in class II mesio-occlusal-distal (MOD) dental restorations using 3D-Finite Element Analysis (FEA). METHODS: Four 3D-FE models (A-D) of teeth, adhesively restored with different filling materials, were created and analyzed in comparison with a 3D model (E) of a sound lower molar...
November 8, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29127669/conserving-connectivity-human-influence-on-subsidy-transfer-and-relevant-restoration-efforts
#4
REVIEW
Emily V Buckner, Daniel L Hernández, Jameal F Samhouri
Conservation efforts tend to focus on the direct impacts humans have on their surrounding environment; however there are also many ways in which people indirectly affect ecosystems. Recent research on ecological subsidies-the transfer of energy and nutrients from one ecosystem to another-has highlighted the importance of nutrient exchange for maintaining productivity and diversity at a landscape scale, while also pointing toward the fragility of ecotones and vulnerability of subsidies to human activities. We review the recent literature on landscape connectivity and ecosystem subsidies from aquatic systems to terrestrial systems...
November 10, 2017: Ambio
https://www.readbyqxmd.com/read/29125248/effects-of-flash-flooding-on-mosquito-and-community-dynamics-in-experimental-pools
#5
C Duchet, G M Moraru, O Segev, M Spencer, A Gershberg Hayoon, L Blaustein
Pulsed disturbances of larval mosquito sites are likely to have a direct negative effect on mosquitoes but may also have indirect effects due to the alteration of community structure. These altered communities may become attractive to gravid mosquitoes searching for oviposition sites when the disturbances decrease the abundance of mosquito antagonists such as competitors, which often results in an increase in mosquito food resources. However, flash flood disturbances in intermittent riverbeds can also remove mosquito food resources such as algae, so that the net effect of flash floods could be either to increase or decrease mosquito abundance...
December 2017: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/29111977/nanos-promotes-epigenetic-reprograming-of-the-germline-by-down-regulation-of-the-thap-transcription-factor-lin-15b
#6
Chih-Yung Sean Lee, Tu Lu, Geraldine Seydoux
Nanos RNA-binding proteins are required for germline development in metazoans, but the underlying mechanisms remain poorly understood. We have profiled the transcriptome of primordial germ cells (PGCs) lacking the nanos homologs nos-1 and nos-2 in C. elegans. nos-1nos-2 PGCs fail to silence hundreds of transcripts normally expressed in oocytes. We find that this misregulation is due to both delayed turnover of maternal transcripts and inappropriate transcriptional activation. The latter appears to be an indirect consequence of delayed turnover of the maternally-inherited transcription factor LIN-15B, a synMuvB class transcription factor known to antagonize PRC2 activity...
November 7, 2017: ELife
https://www.readbyqxmd.com/read/29108332/whether-low-dose-metronomic-oral-cyclophosphamide-improves-the-response-to-docetaxel-in-first-line-treatment-of-non-triple-negative-metastatic-breast-cancer
#7
Jian Zhang, Leiping Wang, Zhonghua Wang, Biyun Wang, Jun Cao, Fangfang Lv, Sheng Zhang, Zhimin Shao, Xichun Hu
Oral metronomic chemotherapy may target tumor cells indirectly via antiangiogenic activity, restoration of anticancer immune response, or induction of tumor dormancy. We initiated the single-center, randomized, open-label, phase II study to determine whether the addition of metronomic cyclophosphamide to docetaxel (T) (w/o trastuzumab) improves overall response rate (ORR) as first-line treatment among patients with non-triple-negative metastatic breast cancer (MBC). Eligible patients with previously untreated non-triple-negative MBC were randomly assigned (1:1) to receive 3-weekly cycles of Metro-TC (T 75mg/m(2), d1 plus oral cyclophosphamide 50 mg daily) or T alone...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29077520/marr-family-transcription-factor-hpar-controls-expression-of-the-vgrr-vgrs-operon-of-xanthomonas-campestris-pv-campestris
#8
Yue Pan, Fang Liang, Ru-Jiao Li, Wei Qian
MarR-family transcription factors (TFs), which regulate the expression of virulence factors and other physiological pathways in pathogenic bacteria, are regarded as ideal molecular targets for the development of novel antimicrobial strategies. In the plant bacterial pathogen Xanthomonas campestris pv. campestris, HpaR, a typical MarR-family TF, is associated with bacterial virulence, but its mechanism of virulence regulation remains unclear. Here, we dissected the HpaR regulon using high-throughput RNA sequencing and chromatin immunoprecipitation sequencing...
October 27, 2017: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/29071561/color-adjustment-potential-of-resin-composites
#9
Branka Trifkovic, John M Powers, Rade D Paravina
OBJECTIVES: The purpose of this study was to evaluate color adjustment potential (CAP) of resin composites. MATERIALS AND METHODS: Two shades of each of eight commercial resin composites and one control shade were evaluated. Visual (color competent observers, controlled conditions) and instrumental color evaluations (spectroradiometer, spectrophotometer) were performed. The data were analyzed by analysis of variance, Fisher's PLSD intervals for comparison of means, and Spearman's rank order correlation...
October 25, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29070160/bioactive-tricalcium-silicate-based-dentin-substitute-as-an-indirect-pulp-capping-material-for-primary-teeth-a-12-month-follow-up
#10
Arturo Garrocho-Rangel, Karina Quintana-Guevara, Rocío Vázquez-Viera, Juana María Arvizu-Rivera, Héctor Flores-Reyes, Diana María Escobar-García, Amaury Pozos-Guillén
PURPOSE: The purpose of this study was to evaluate the clinical and radiographic outcomes of a bioactive tricalcium silicate [Ca3SiO5]-based dentin substitute and a light-activated calcium hydroxide [Ca(OH)2]-based liner as indirect pulp treatment (IPT) interventions for vital primary molars with carious lesions approaching the pulp. METHODS: Eighty children, aged four to eight years old, with 160 bilateral primary teeth without signs or symptoms of irreversibly inflamed or degenerative pulp tissue were treated in a split-mouth design trial comparing IPT using Ca3SiO5 or Ca(OH)2...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29068002/engineered-d2r-variants-reveal-the-balanced-and-biased-contributions-of-g-protein-and-%C3%AE-arrestin-to-dopamine-dependent-functions
#11
Samuel J Rose, Thomas F Pack, Sean M Peterson, Kaitlin Payne, Emiliana Borrelli, Marc G Caron
The dopamine D2 receptor (D2R), like many G-protein coupled-receptors, signals through G-protein and β-arrestin-dependent pathways. Preferential activation of one of these pathways is termed functional selectivity or biased signaling and is a promising therapeutic strategy. Though biased signaling through D2Rs has been demonstrated, acquiring the mechanistic details of biased D2R/G-protein and D2R/β-arrestin signaling in vivo has been challenging due to the lack of techniques that specifically target these interactions in discrete cell populations...
October 25, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29062602/range-expansion-of-a-fouling-species-indirectly-impacts-local-species-interactions
#12
Cori J Speights, Michael W McCoy
We investigated how recent changes in the distribution and abundance of a fouling organism affected the strength of interactions between a commercially important foundation species and a common predator. Increases in the abundance of boring sponges that bioerode the calcified shells of oysters and other shelled organisms have been attributed to increased salinization of estuarine ecosystems. We tested the hypothesis that fouling by boring sponges will change the interaction strength between oysters and a common predator (stone crabs)...
2017: PeerJ
https://www.readbyqxmd.com/read/29061380/influence-of-cervical-margin-relocation-cmr-on-periodontal-health-12-month-results-of-a-controlled-trial
#13
Marco Ferrari, Serhat Koken, Simone Grandini, Edoardo Ferrari Cagidiaco, Tim Joda, Nicola Discepoli
OBJECTIVES: The concept of Cervical Margin Relocation (CMR) consists on placing a base layer of direct resin composite to elevate supra-gingivally the proximal indirect bonded restorations. The aims of this clinical study were to evaluate 1. Bleeding on Probing (BoP) on posterior indirect restorations with one interproximal margin relocated cervically, and 2. possible correlation between depth of the interproximal margins and BoP. METHODS: CMR (Group 1) and shoulder preparations (Group 2) were performed in 35 posterior teeth and evaluated after 12 months (T12)...
October 20, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29042725/the-effect-of-polymerization-and-preparation-techniques-on-the-microleakage-of-composite-laminate-veneers
#14
Neslihan Celik, Merve Iscan Yapar, Numan Taşpınar, Nilgun Seven
BACKGROUND: Marginal leakage is the important factor influencing the maintenance of dental esthetic. AIM: The purpose of this study was to evaluate the relationship between the preparation techniques and type of polymerization techniques on microleakage of composite laminate veneers. MATERIALS AND METHODS: Ninety-one same sized, caries-free human maxillary central incisors were randomly assigned to 13 groups (n = 7) and were designed with four different preparation techniques (window type, feather type, bevel type, and incisal overlap type)...
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29038961/association-of-indirect-restorations-with-past-caries-history-and-present-need-for-restorative-treatment-in-the-northern-finland-birth-cohort-1966
#15
Anne Laajala, Pasi Karhatsu, Paula Pesonen, Marja-Liisa Laitala, Ritva Näpänkangas, Aune Raustia, Vuokko Anttonen
OBJECTIVES: The objective of this study is to examine the prevalence of indirect restorations and their association with past caries history and present need for restorative treatment among adults in Northern Finland. MATERIALS AND METHODS: The study population was a subsample of the Northern Finland Birth Cohort 1966 (n = 1961). The oral examinations were performed in 2012-2013. Indirect restorations (inlays/onlays and single crowns) were recorded tooth wise...
October 16, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29030578/simultaneous-fusion-imaging-and-encryption-of-multiple-objects-using-a-single-pixel-detector
#16
Shi Dongfeng, Huang Jian, Wang Yingjian, Yuan Kee, Xie Chenbo, Liu Dong, Zhu Wenyue
A novel technique for the simultaneous fusion, imaging and encryption of multiple objects using a single-pixel detector is proposed. Here, encoded multiplexing patterns are employed to illuminate multiple objects simultaneously. The mixed light reflected from the objects is detected by a single-pixel detector. An iterative reconstruction method is used to restore the fused image by summing the multiplexed patterns and detected intensities. Next, clear images of the objects are recovered by decoding the fused image...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29024789/in-vitro-pharmacological-characterization-of-the-bispyridinium-non-oxime-compound-mb327-and-its-2-and-3-regioisomers
#17
K V Niessen, T Seeger, S Rappenglück, T Wein, G Höfner, K T Wanner, H Thiermann, F Worek
The primary toxic mechanism of organophosphorus compounds, i.e. nerve agents or pesticides, is based on the irreversible inhibition of acetylcholinesterase. In consequence of the impaired hydrolysis, the neurotransmitter acetylcholine accumulates in cholinergic synapses and disturbs functional activity of nicotinic and muscarinic acetylcholine receptors by overstimulation and subsequent desensitization. The resulting cholinergic syndrome will become acute life-threatening, if not treated adequately. The current standard treatment, consisting of administration of a competitive mAChR antagonist (e...
October 9, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29017759/differential-cytotoxic-effects-on-odontoblastic-cells-induced-by-self-adhesive-resin-cements-as-a-function-of-the-activation-protocol
#18
Paulo Henrique Perlatti D'Alpino, Gioconda Emanuella Diniz de Dantas Moura, Silvana Coelho de Arruda Barbosa, Lygia de Azevedo Marques, Marcos Nogueira Eberlin, Fábio Dupart Nascimento, Ivarne Luis Dos Santos Tersariol
OBJECTIVES: To evaluate the cytotoxic effects of exposing odontoblast cells to a variety of commercial self-adhesive cements polymerized using different activation modes. METHODS: Five cements: MaxCem Elite (MAX), Bifix SE (BSE), G-Cem LinkAce (GCE), Clearfil SA Luting (CAS), and RelyX U200 (U200) were mixed, dispensed into molds, and distributed in groups, according to polymerization protocols: immediate photoactivation; delayed photoactivation (10min self-curing plus light-activation); and chemical activation (no light exposure)...
October 7, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28991221/a-non-coding-function-of-tyrp1-mrna-promotes-melanoma-growth
#19
David Gilot, Mélodie Migault, Laura Bachelot, Fabrice Journé, Aljosja Rogiers, Emmanuelle Donnou-Fournet, Ariane Mogha, Nicolas Mouchet, Marie-Laure Pinel-Marie, Bernard Mari, Tristan Montier, Sébastien Corre, Arthur Gautron, Florian Rambow, Petra El Hajj, Rania Ben Jouira, Sophie Tartare-Deckert, Jean-Christophe Marine, Brice Felden, Ghanem Ghanem, Marie-Dominique Galibert
Competition among RNAs to bind miRNA is proposed to influence biological systems. However, the role of this competition in disease onset is unclear. Here, we report that TYRP1 mRNA, in addition to encoding tyrosinase-related protein 1 (TYRP1), indirectly promotes cell proliferation by sequestering miR-16 on non-canonical miRNA response elements. Consequently, the sequestered miR-16 is no longer able to repress its mRNA targets, such as RAB17, which is involved in melanoma cell proliferation and tumour growth...
November 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/28989247/targeting-mitochondrial-dysfunction-for-the-treatment-of-diabetic-complications-pharmacological-interventions-through-natural-products
#20
REVIEW
Aakruti Arun Kaikini, Divya Manohar Kanchan, Urvi Narayan Nerurkar, Sadhana Sathaye
Diabetes mellitus is a chronic hyperglycemic condition with deleterious effects on microcirculation, resulting in diabetic complications. Chronic hyperglycemia induces the generation of reactive oxygen species (ROS), which are the key pathological triggers in the development of diabetic complications. ROS are responsible for the activation of various pathways involved in the genesis of diabetic complications, mitochondrial dysfunction, as well as insulin resistance. The review describes normal mitochondrial physiology and abnormal alterations, which occur in response to hyperglycemia...
July 2017: Pharmacognosy Reviews
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