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Correctional medicine

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https://www.readbyqxmd.com/read/29933712/corrigendum
#1
(no author information available yet)
Liu J, Fei L, Huang G-Q, Shang X-K, Liu M, Pei Z-J, Zhang Y-X. Right ventricle performances with echocardiography and 99m Tc myocardial perfusion imaging in pulmonary arterial hypertension patients. Exp Biol Med 2018;243(9):754-761. In this article, the first author's affiliation was incorrect in the OnlineFirst and print versions. It should have appeared as 'Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China'. This has been corrected in the online article...
January 1, 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29925956/author-correction-pancreas-regeneration
#2
Qiao Zhou, Douglas A Melton
Change history: In this Insight Review, '1989' has been changed to '1998' in the sentence "This deep understanding of pancreatic development was put to the service of regenerative medicine in 1998, when human embryonic stem cells (hES cells) were successfully cultured and opened the door to developing methods of deriving pancreatic islets from hES cells66.". This error has been corrected online.
June 20, 2018: Nature
https://www.readbyqxmd.com/read/29925125/-technical-specification-for-clinical-application-of-critical-ultrasonography
#3
M G Yin, X T Wang, D W Liu, Y G Chao, X D Guan, Y Kang, J Yan, X C Ma, Y Q Tang, Z J Hu, K J Yu, D C Chen, Y H Ai, L N Zhang, H M Zhang, J Wu, L X Liu, R Zhu, W He, Q Zhang, X Ding, L Li, Y Li, H T Liu, Q B Zeng, X Si, H Chen, J W Zhang, Q H Xu, W J Chen, X K Chen, D Z Huang, S H Cai, X L Shang, J Guan, J Du, L Zhao, M J Wang, S Cui, X M Wang, R Zhou, X Y Zeng, Y P Wang, L W Lyu, W H Zhu, Y Zhu, J Duan, J Yang, H Yang
Critical ultrasonography(CUS) is different from the traditional diagnostic ultrasound, the examiner and interpreter of the image are critical care medicine physicians. The core content of CUS is to evaluate the pathophysiological changes of organs and systems and etiology changes. With the idea of critical care medicine as the soul, it can integrate the above information and clinical information, bedside real-time diagnosis and titration treatment, and evaluate the therapeutic effect so as to improve the outcome...
June 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29923058/evaluation-breast-cancer-information-on-the-internet-in-arabic
#4
Lamya Alnaim
Nowadays, medical information regarding various diseases and disorders is available online. The Internet has become the first choice for the patient when it comes to gathering detailed information about a disease or problem. Therefore, in view of this frequent occurrence, the information that is provided online needs to be accurate; providing comprehensive facts, transparency, and quality. A study was carried out to determine the accuracy of information related to breast cancer on various websites. Websites which share information online about breast cancer, in the Arabic language, were selected...
June 20, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29922841/upper-arch-flap-combined-with-extended-incision-of-lower-eyelid-a-modified-epicanthoplasty-in-correcting-epicanthus
#5
Song Zhang, Hongyu Xue
BACKGROUND: The epicanthus, a lengthways cambered skinfold around the inner canthus, is particularly common in Orientals. The purpose of this study was to evaluate the surgical outcomes for patients with epicanthus after the application of a new surgical technique. METHODS: A total of 753 patients with epicanthus underwent epicanthoplasty in our hospital from October 2009 to March 2017 and were enrolled in this study. All patients were treated with upper arch flap combined with extended incision of the lower eyelid surgical method, and the effects of the surgery were assessed by photographic analysis and satisfaction surveys...
June 19, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29917007/changes-in-the-practice-of-pediatric-orthopaedic-surgeons-over-the-past-decade-analysis-of-the-database-of-the-american-board-of-orthopaedic-surgery
#6
Pooya Hosseinzadeh, Clarabelle A DeVries, Ena Nielsen, Lindsay A Andras, Megan Mignemi, Jeffrey R Sawyer, John M Flynn, Stephen A Albanese
BACKGROUND: There has been an increase in the number of the graduates of pediatric orthopaedic fellowship programs over the past decade creating the potential for increased competition in the field. The purpose of this study was to analyze the effect of increased number of pediatric orthopaedic fellowship graduates on case volume as well as the type of procedures performed by recent graduates of pediatric orthopaedic fellowship programs from 2004 to 2014. METHODS: Case logs submitted for the American Board of Orthopaedic Surgery Part II examination by applicants with the self-declared subspecialty of pediatric orthopaedics from 2004 to 2014 were analyzed...
June 18, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29915906/effect-of-shexiang-tongxin-dropping-pills-on-the-immediate-blood-flow-of-patients-with-coronary-slow-flow
#7
Sheng-Huang Wang, Lin Chu, Zhao Xu, Hong-Lin Zhou, Jiang-Fei Chen, Huang-Fu Ning
OBJECTIVE: To observe the immediate effect and safety of Shexiang Tongxin dropping pills ( , STDP) on patients with coronary slow flow (CSF), and furthermore, to explore new evidence for the use of Chinese medicine in treating ischemic chest pain. METHODS: Coronary angiography (CAG) with corrected thrombolysis in myocardial infarction (TIMI) frame count (CTFC) was applied (collected at 30 frames/s). The treatment group included 22 CSF patients, while the control group included 22 individuals with normal coronary flow...
June 18, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29914921/determining-the-pathogenicity-of-a-genomic-variant-of-uncertain-significance-using-crispr-cas9-and-human-induced-pluripotent-stem-cells
#8
Ning Ma, Joe Zhang, Ilanit Itzhaki, Sophia L Zhang, Haodong Chen, Francois Haddad, Tomoya Kitani, Kitchener D Wilson, Lei Tian, Rajani Shrestha, Haodi Wu, Chi Keung Lam, Nazish Sayed, Joseph C Wu
Background -The progression toward low-cost and rapid next-generation sequencing has uncovered a multitude of variants of uncertain significance (VUS) in both patients and asymptomatic "healthy" individuals. A VUS is a rare or novel variant for which disease pathogenicity has not been conclusively demonstrated or excluded, and thus cannot be definitively annotated. VUS, therefore, pose critical clinical interpretation and risk-assessment challenges, and new methods are urgently needed to better characterize their pathogenicity...
June 18, 2018: Circulation
https://www.readbyqxmd.com/read/29911484/the-need-for-an-alternative-method-to-determine-intravascular-volumes
#9
L M Lobigs, P Peeling, B Dawson, Y O Schumacher
It is well described that numerous environmental factors, including exercise, modulate plasma volume (PV). These modulations prove problematic when a number of haematological markers are measured as a concentration in blood plasma. A primary example is haemoglobin concentration ([Hb]), a marker of erythropoiesis commonly used within medicine and also used to detect blood doping. Natural changes in PV can confound [Hb] values when a volume change is detected rather than a true change in haemoglobin mass (Hbmass ) (e...
June 17, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29911289/homing-and-tracking-of-iron-oxide-labelled-mesenchymal-stem-cells-after-infusion-in-traumatic-brain-injury-mice-a-longitudinal-in-vivo-mri-study
#10
Sushanta Kumar Mishra, Subash Khushu, Ajay K Singh, Gurudutta Gangenahalli
Stem cells transplantation has emerged as a promising alternative therapeutic due to its potency at injury site. The need to monitor and non-invasively track the infused stem cells is a significant challenge in the development of regenerative medicine. Thus, in vivo tracking to monitor infused stem cells is especially vital. In this manuscript, we have described an effective in vitro labelling method of MSCs, a serial in vivo tracking of implanted stem cells at traumatic brain injury (TBI) site through 7 T magnetic resonance imaging (MRI)...
June 17, 2018: Stem Cell Reviews
https://www.readbyqxmd.com/read/29906380/points-pearls-managing-shoulder-injuries-in-the-emergency-department-fracture-dislocation-and-overuse
#11
Richard Pescatore, Andrew Nyce, Nachi Gupta, Jeffrey Nusbaum
The complex structures of the shoulder can be injured by fracture, dislocation, and overuse, and correctly identifying and classifying injury is essential to avoiding pain, disability, and life- and limb-threatening complications. This issue presents a systematic approach to classifying shoulder injuries based on the mechanism of injury and clinical presentation, choosing appropriate imaging, and determining the best strategies for treatment, including reduction, surgical consultation, or outpatient referral...
June 1, 2018: Emergency Medicine Practice
https://www.readbyqxmd.com/read/29904594/towards-precision-medicine-the-application-of-omics-technologies-in-asthma-management
#12
Chiara Scelfo, Carla Galeone, Francesca Bertolini, Marco Caminati, Patrizia Ruggiero, Nicola Facciolongo, Francesco Menzella
Asthma is a chronic obstructive respiratory disease characterised by bronchial inflammation. Its biological and clinical features have been widely explored and a number of pharmacological treatments are currently available. Currently several aspects of asthma pathophysiological background remain unclear, and this is crucial for the traditional asthma phenotype approach as well as for new endotype definition. In this scenario, the identification of new molecular and clinical biomarkers may be helpful in order to better understand the disease, define specific diagnostic tools and highlight relevant novel targets for pharmacology treatments...
2018: F1000Research
https://www.readbyqxmd.com/read/29904053/naoxintong-capsules-inhibit-the-development-of-diabetic-nephropathy-in-db-db-mice
#13
Shu Yang, Mengyang Liu, Yuanli Chen, Chuanrui Ma, Lipei Liu, Buchang Zhao, Yong Wang, Xiaoju Li, Yan Zhu, Xiumei Gao, Deling Kong, Yajun Duan, Jihong Han, Xiaoxiao Yang
NaoXinTong Capsule (NXT), a Chinese medicine, is currently used to treat patients with cardiovascular and cerebrovascular diseases. Clinical observations indicate its anti-diabetic functions with unclear mechanisms. Herein, we report the effect of NXT on diabetic nephropathy (DN). Type 2 diabetic db/db mice were treated with NXT for 14 weeks. In the course of treatment, NXT reduced diabetes-increased glucose levels and improved renal functions. At the end of treatment, we found that NXT ameliorated serum lipid profiles and other biochemical parameters...
June 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29903477/model-selection-for-clustering-of-pharmacokinetic-responses
#14
Rui P Guerra, Alexandra M Carvalho, Paulo Mateus
BACKGROUND AND OBJECTIVE: Pharmacokinetics comprises the study of drug absorption, distribution, metabolism and excretion over time. Clinical pharmacokinetics, focusing on therapeutic management, offers important insights towards personalised medicine through the study of efficacy and toxicity of drug therapies. This study is hampered by subject's high variability in drug blood concentration, when starting a therapy with the same drug dosage. Clustering of pharmacokinetics responses has been addressed recently as a way to stratify subjects and provide different drug doses for each stratum...
August 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29901073/-corrigendum-microrna%C3%A2-181a%C3%A2-5p-functions-as-an-oncogene-in-renal-cell-carcinoma
#15
Yulin Lai, Liwen Zhao, Jia Hu, Jing Quan, Peijie Chen, Jinling Xu, Xin Guan, Yongqing Lai, Liangchao Ni
Subsequently to the publication of the article, the authors have recognized a need to correct some of its content in order to clarify the accuracy of the article's information. First, Dr Yongqing Lai should have been included as the joint corresponding author for this paper. Therefore, the information in the correspondence box should have been as follows (changes are indicated in bold): Correspondence to: Professor Liangchao Ni or Dr Yongqing Lai, Department of Urology, Peking University Shenzhen Hospital, 1120 Lianhua Road, Shenzhen, Guangdong 518036, P...
June 1, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29894957/spectroscopic-and-computational-evaluation-on-the-binding-of-safranal-with-human-serum-albumin-role-of-inner-filter-effect-in-fluorescence-spectral-correction
#16
Mohd Sajid Ali, Hamad A Al-Lohedan
For determining the pharmacological properties of medicinal compounds, their binding with serum albumins is very crucial. Herein, we have selected safranal, a major constituent of saffron which is known to retain a number of medicinal properties including antioxidant, anti-inflammatory, tumoricidal, anti-genotoxic, and anti-aging activities; and studied its mechanism of binding with human serum albumin at physiological pH using various spectroscopic methods along with computational approach using molecular docking...
May 29, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29893013/online-virtual-cases-to-teach-resource-stewardship
#17
Linghong Linda Zhou, Gordon Tait, Sharron Sandhu, Amanda Steiman, Shirley Lake
BACKGROUND: As health care costs rise, medical education must focus on high-value clinical decision making. To teach and assess efficient resource use in rheumatology, online virtual interactive cases (VICs) were developed to simulate real patient encounters to increase price transparency and reinforce cost consciousness. To teach and assess efficient resource use in rheumatology, online virtual interactive cases (VICs) were developed METHODS: The VIC modules were distributed to a sample of medical students and internal medicine residents, who were required to assess patients, order appropriate investigations, develop differential diagnoses and formulate management plans...
June 11, 2018: Clinical Teacher
https://www.readbyqxmd.com/read/29892041/effectiveness-of-vitamin-d-therapy-in-improving-metabolomic-biomarkers-in-obesity-phenotypes-two-randomized-clinical-trials
#18
Farshad Farzadfar, Abolghasem Djazayery, Lu Qi, Minoo Bagheri, Mir Saeed Yekaninejad, Maryam Chamari, Maryam Naderi, Zarin Ebrahimi, Berthold Koletzko, Olaf Uhl
BACKGROUND: Uncertainty remains about the effect of vitamin D therapy on biomarkers of health status in obesity. The molecular basis underlying this controversy is largely unknown. OBJECTIVE: To address the existing gap, our study sought to compare changes in metabolomic profiles of obesity phenotypes (metabolically healthy obese (MHO) and metabolically unhealthy obese (MUHO)) patients with sub-optimal levels of vitamin D following vitamin D supplementation. METHODS: We conducted two randomized double-blind clinical trials on participants with either of the two obesity phenotypes from Tehran province...
June 11, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29891124/retention-of-cricothyrotomy-skills-by-paramedics-using-a-wire-guided-technique
#19
J A March, M J Kiemeney, J De Guzman, J D Ferguson
INTRODUCTION: Cricothyrotomy may be necessary for airway management when a patient's airway cannot be maintained through standard techniques such as oral airway placement, blind insertion airway device, or endotracheal intubation. Wire-guided cricothyrotomy is one of many techniques used to perform a cricothyrotomy. Although there is some controversy over which cricothyrotomy technique is superior, there is no published data regarding long term retention rates. The purpose of this study is to determine whether ground based paramedics can be taught and are able to retain the skills necessary to successfully perform a wire-guided cricothyrotomy...
May 31, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29889160/extension-of-the-international-atomic-energy-agency-phantom-study-in-image-quantification-results-of-multicentre-evaluation-in-croatia
#20
Darko Grošev, Marin Gregov, Miroslava Radić Wolfl, Branislav Krstonošić, Dea Dundara Debeljuh
To make quantitative methods of nuclear medicine more available, four centres in Croatia participated in the national intercomparison study, following the materials and methods used in the previous international study organized by the International Atomic Energy Agency (IAEA). The study task was to calculate the activities of four Ba sources (T1/2=10.54 years; Eγ=356 keV) using planar and single-photon emission computed tomography (SPECT) or SPECT/CT acquisitions of the sources inside a water-filled cylindrical phantom...
June 7, 2018: Nuclear Medicine Communications
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