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Loin pain hematuria syndrome

Hulya Nalcacioglu, Meltem Ceyhan Bilgici, Demet Tekcan, Gurkan Genc, Yakup Bostanci, Yarkin Kamil Yakupoglu, Saban Sarikaya, Ozan Ozkaya
The purpose of this study was to evaluate the clinical characteristics of 44 pediatric patients who were diagnosed as having nutcracker syndrome (NCS). We also investigated the left renal vein Doppler ultrasonography (DUS) results, to determine whether or not there was an association between clinical symptoms and DUS findings among these patients. The clinical data from 44 pediatric patients who were diagnosed as having NCS from January 2008 to December 2015 were retrospectively reviewed. We grouped the patients according to the presenting symptoms as symptomatic (loin pain; macroscopic hematuria or both) and non-symptomatic (microscopic hematuria and proteinuria were detected incidentally) and evaluated the left renal vein DUS indices in these two groups separately...
August 13, 2018: Journal of Clinical Medicine
Karel Decaestecker, Benjamin Van Parys, Jeroen Van Besien, Nicolas Doumerc, Liesbeth Desender, Caren Randon, Frederic De Ryck, Thomas Tailly, Matthias Beysens, Carl Van Haute, Diederik Ponette, Kathia De Man, Piet Hoebeke, Frank Vermassen
BACKGROUND: Kidney autotransplantation (KAT) is the ultimate way to salvage kidneys with complex renovascular, ureteral, or malignant pathologies that are not amenable to in situ reconstruction. A minimally invasive approach could broaden its adoption. OBJECTIVE: To describe operative technique, perioperative complications, and early functional outcomes of robot-assisted kidney autotransplantation (RAKAT). DESIGN, SETTING, AND PARTICIPANTS: Retrospective review of prospectively collected data regarding consecutive patients undergoing RAKAT between March 2017 and February 2018 at two university hospitals...
March 2018: European Urology Focus
Bhanu Prasad, Shelley Giebel, Francisco Garcia, Kunal Goyal, Pratima Shrivastava, Warren Berry
Introduction: Loin pain hematuria syndrome (LPHS) is characterized by severe unilateral or bilateral loin pain that suggests a renal origin but occurs in the absence of identifiable or relevant urinary tract disease. Hematuria can either be microscopic or macroscopic, but the renal abnormalities responsible for the hematuria are unexplained. Debilitating pain refractory to conventional pain medications is the main cause of morbidity. Methods: We conducted a single-arm, single-center study...
May 2018: KI Reports
Bhanu Prasad, Shelley Giebel, Francisco Garcia, Kunal Goyal, Jennifer Rose St Onge
Loin pain hematuria syndrome (LPHS) is a painful and incapacitating condition that typically affects young women. Treatment options, including opiates and/or surgical denervation of the renal nerves by autotransplantation, have variable success. In this report, we describe the successful use of endovascular renal nerve ablation in this population. Four women with LPHS and intractable pain unresponsive to conservative measures underwent endovascular ablation of the renal nerves between July and November 2015 using the Vessix renal denervation system...
January 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Adeel S Zubair, Wisit Cheungpasitporn, Stephen B Erickson, Mikel Prieto
OBJECTIVE: The objective of this study is to assess clinical and safety outcomes after laparoscopic nephrectomy with autotransplantation for loin pain-hematuria syndrome (LPHS). METHODS: We conducted telephone interviews using structured questionnaires and retrospectively reviewed data on all patients who underwent laparoscopic nephrectomy with autotransplantation for LPHS between January 2000 and May 2014. RESULTS: A total of 24 laparoscopic nephrectomies with renal autotransplantation of 21 patients with LPHS refractory to conservative medical treatment were reviewed...
May 17, 2016: Journal of Evidence-based Medicine
Adeel S Zubair, Hassan Salameh, Stephen B Erickson, Mikel Prieto
Loin pain hematuria syndrome (LPHS), first described in 1967, is a rare pain syndrome, which is not well understood. The syndrome is characterized by severe intermittent or persistent flank pain, either unilateral or bilateral, associated with gross or microscopic hematuria. LPHS is a diagnosis of exclusion as there still is not a consensus of validated diagnostic criteria, though several criteria have been proposed. The wide differential diagnosis would suggest a meticulous yet specific diagnostic work-up depending on the individual clinical features and natural history...
February 2016: Clinical Kidney Journal
Nick G Cowan, John S Banerji, Richard B Johnston, Brian D Duty, Bjørn Bakken, Jason C Hedges, Paul M Kozlowski, Thomas R Hefty, John M Barry
PURPOSE: Renal autotransplantation is an infrequently performed procedure. It has been used to manage complex ureteral disease, vascular anomalies and chronic kidney pain. We reviewed our 27-year experience with this procedure. MATERIALS AND METHODS: This is a retrospective, observational study of 51 consecutive patients who underwent renal autotransplantation, including 29 at Oregon Health and Science University between 1986 and 2013, and 22 at Virginia Mason Medical Center between 2007 and 2012...
November 2015: Journal of Urology
Fahd Syed, Quynh Lam, Najindra Maharjan, Didier Portilla, Matthew R Smeds, Daniel Borja-Cacho
The syndrome of loin pain hematuria in the absence of stones is poorly understood but must be considered in the differential diagnosis for patients with clinical manifestations resembling nephrolithiasis. A 22-year-old white female with a 4-year history of left flank pain and hematuria underwent an extensive workup with normal renal ultrasound and cystourethroscopies. CT scan and MRI revealed a retro-aortic left renal vein. Posterior nutcracker syndrome was considered the most likely diagnosis. The patient underwent a left laparoscopic nephrectomy with auto-transplantation in the right iliac fossa...
May 2015: Journal of the Arkansas Medical Society
Sahar Taba Taba Vakili, Tausif Alam, Hans Sollinger
Loin pain hematuria syndrome is a rare disease with a prevalence of ∼0.012%. The most prominent clinical features include periods of severe intermittent or persistent unilateral or bilateral loin pain accompanied by either microscopic or gross hematuria. Patients with loin pain hematuria syndrome initially present with hematuria, flank pain, or most often both hematuria and flank pain. Kidney biopsies from patients with loin pain hematuria typically reveal only minor pathologic abnormalities. Further, loin pain hematuria syndrome is not associated with loss of kidney function or urinary tract infections...
September 2014: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
A O Takure, O B Shittu, S A Adebayo, C A Okolo, P T Sotunmbi
BACKGROUND: To review all the cases of the patients with renal cell carcinoma seen during the study period and to determine the pattern of presentation, number of operable cases, histological types and outcome of treatment. MATERIALS AND METHODS: The data of the patients with renal cell carcinoma was retrieved from the Urology division audit book, theatre record books and case files from the health records department and pathology register in the department of pathology...
September 2013: African Journal of Medicine and Medical Sciences
Susan M Moeschler, Bryan C Hoelzer, Jason S Eldrige
INTRODUCTION: Chronic abdominal and flank pain can be multifactorial and difficult to treat. Loin pain hematuria syndrome (LPHS) is a rare clinical cause of chronic abdominal and flank pain and is a diagnosis of exclusion with limited treatment options, ranging from medications to renal autotransplantation or even nephrectomy in resistant cases. CASE DESCRIPTION: A 50-year-old man with a history of recurrent nephrolithiasis secondary to hypercalcemia presented to the pain clinic with bilateral flank pain...
November 2013: Clinical Journal of Pain
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