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Raf Aerts, Olivier Honnay, An Van Nieuwenhuyse
Introduction: Natural environments and green spaces provide ecosystem services that enhance human health and well-being. They improve mental health, mitigate allergies and reduce all-cause, respiratory, cardiovascular and cancer mortality. The presence, accessibility, proximity and greenness of green spaces determine the magnitude of their positive health effects, but the role of biodiversity (including species and ecosystem diversity) within green spaces remains underexplored. This review describes mechanisms and evidence of effects of biodiversity in nature and green spaces on human health...
July 10, 2018: British Medical Bulletin
Hiroto Shimajiri, Hiroyuki Egi, Masateru Yamamoto, Masatoshi Kochi, Shoichiro Mukai, Hideki Ohdan
INTRODUCTION: Postoperative chylous ascites is a rare complication of colorectal surgery. Conservative management is usually effective in most cases of the postoperative chylous ascites. However, surgical intervention is performed for refractory cases. PRESENTATION OF CASE: A 31-year-old man with neuroendocrine carcinoma developed chylous ascites after laparoscopic descending colectomy with D3 lymphadenectomy. Conservative treatment including total parenteral nutrition and somatostatin analogue failed and surgical intervention via laparoscopy was performed for the refractory chylous ascites...
June 23, 2018: International Journal of Surgery Case Reports
Hassan Anwer, Jae-Woo Park
Synergy between surface adsorption and photocatalysis is key for effective contaminant degradation in the liquid phase. Herein, we report a heterojunction photocatalyst of reduced graphene oxide (rGO)/zirconium dioxide (ZrO2 )/silver phosphate (Ag3 PO4 ) that incorporates this synergy for 4-nitrophenol (PNP) removal. Compared with other photocatalyst combinations, ZrO2 and Ag3 PO4 coupling generates reactive species with greater degradation potential. ZrO2 and rGO were synthesized by a green approach using a one-step hydrothermal reaction in ethanol-water...
July 8, 2018: Journal of Hazardous Materials
Khalid M Omer
Carbon quantum dots are becoming powerful fluorophore materials for metal ion analysis. Here, highly passivated green phosphorous and nitrogen co-doped carbon quantum dots (C-dots) were prepared using low-temperature carbonization route. Strong green fluorescence emission around 490 nm and excitation wavelength independent C-dots were obtained. Morphological, surface, and optical properties of the C-dots were characterized. Fluorescence emission of C-dots was quenched selectively by copper ions and restored by adding copper chelators, such as EDTA and sulfide ions...
July 13, 2018: Analytical and Bioanalytical Chemistry
Luz E Casados-Vázquez, Dennis K Bideshi, José E Barboza-Corona
The structural gene that encodes thurincin H, a bacteriocin produced by Bacillus thuringiensis, is harboured in a genetic cluster (thnP, E, D, R, A1, A2, A3, B, T, I) that controls its synthesis, modification, secretion and autoimmunity. The specific genes in the cassette that confer immunity in B. thuringiensis to thurincin H are unknown. To identify these immunity determinants, we generated constructs that were used to transform a natural thurincin H-sensitive B. thuringiensis strain (i.e. Btk 404), and resistance or susceptibility to the bacteriocin in resultant recombinants was evaluated...
July 13, 2018: Antonie Van Leeuwenhoek
Marina Gabriela Monteiro Carvalho Mori da Cunha, Giorgia Giacomazzi, Geertje Callewaert, Lucie Hympanova, Francesca Russo, Greetje Vande Velde, Rik Gijsbers, Maarten Albersen, Maurilio Sampaolesi, Jan Deprest
Currently cell therapy is considered as an experimental strategy to assist the healing process following simulated vaginal birth injury in rats, boosting the functional and morphologic recovery of pelvic floor muscles and nerves. However, the optimal administration route and dose still need to be determined. Mesangioblasts theoretically have the advantage that they can differentiate in skeletal and smooth muscle. We investigated the fate of mesoangioblasts transduced with luciferase and green fluorescent protein reporter genes (rMABseGFP/fLUC ) using bioluminescence, immunofluorescence and RT-PCR in rats undergoing simulated birth injury...
July 13, 2018: Scientific Reports
Chuan-Chih Hsu, Yingfang Zhu, Justine V Arrington, J Sebastian Paez, Pengcheng Wang, Peipei Zhu, I-Hsuan Chen, Jian-Kang Zhu, Weiguo Andy Tao
Phosphorylation-mediated signaling transduction plays a crucial role in the regulation of plant defense mechanisms against environmental stresses. To address the high complexity and dynamic range of plant proteomes and phosphoproteomes, we present a universal sample preparation procedure that facilitates plant phosphoproteomic profiling. This advanced workflow significantly improves phosphopeptide identifications, enabling deep insight into plant phosphoproteomes. We then applied the workflow to study the phosphorylation events involved in tomato cold tolerance mechanisms...
July 13, 2018: Molecular & Cellular Proteomics: MCP
Cheng Peng, Xiao-Hui Dong, Jia-Lin Liu, Yu-Long Tao, Chun-Fang Xu, Li-Ping Wang, Chun-Long Liu, Ding-Feng Su, Xia Tao, Chuan Zhang, Alex F Chen, He-Hui Xie
There is a pressing need for new approaches to preventing stroke. Endothelial progenitor cells (EPCs) promote vascular repair and revascularization in the ischemic brain. This study sought to evaluate whether preventive delivery of EPCs could prevent or protect against stroke. Stroke-prone spontaneously hypertensive rats (SHR-SP) received a single injection of EPCs, and their survival time was monitored. In addition, at 28 and/or 42 days after a single injection of EPCs, SHR-SP and mice were subjected to cerebral ischemia, and cerebral ischemic injury, local angiogenesis and in vivo EPC integration were determined...
July 13, 2018: Clinical Science (1979-)
Matthew J Sullivan, Glen C Ulett
Group B Streptococcus (GBS) is a gram-positive bacterium associated with various diseases in humans and animals. Many studies have examined GBS physiology, virulence and microbe-host interactions using diverse imaging approaches, including fluorescence microscopy. Strategies to label and visualize GBS using fluorescence biomarkers have been limited to antibody-based methods or non-specific stains that bind DNA or protein; an effective plasmid-based system to label GBS with a fluorescence biomarker would represent a useful visualization tool...
July 13, 2018: Applied and Environmental Microbiology
Alison J Kriegel, Scott S Terhune, Andrew S Greene, Kathleen R Noon, Michael S Pereckas, Mingyu Liang
Targeting mRNAs via seed region pairing is the canonical mechanism by which microRNAs (miRNAs) regulate cellular functions and disease processes.  Emerging evidence suggests miRNAs might also act through other mechanisms.  miRNA isomers that contain identical seed region sequences, such as miR-29a and miR-29b, provide naturally occurring, informative models for identifying those miRNA effects that are independent of seed region pairing.  miR-29a and miR-29b are both expressed in HeLa cells, and miR-29b has been reported to localize to the nucleus in early mitosis because of unique nucleotide sequences on its 3' end...
July 13, 2018: Journal of Biological Chemistry
Peter Day, Richard M Green, Melanie Gross, Lennart Weltje, James R Wheeler
The ongoing debate concerning the regulation of endocrine disruptors, has increasingly led to questions concerning the current testing of chemicals and whether this is adequate for the assessment of potential endocrine disrupting effects. This paper describes the current testing approaches for plant protection product (PPP) active substances in the European Union and the United States and how they relate to the assessment of endocrine disrupting properties for human and environmental health. This includes a discussion of whether the current testing approaches cover modalities other than the estrogen, androgen, thyroid and steroidogenesis (EATS) pathways, sensitive windows of exposure, adequate assessment of human endocrine disorders and wildlife species, and the determination of thresholds for endocrine disruption...
July 10, 2018: Toxicology Letters
Allison E Fay, Stefanie P Ferreri, Greene Shepherd, Kristin Lundeen, Gretchen L Tong, Trista Pfeiffenberger
OBJECTIVES: To determine the awareness, collaboration, and perceived values and barriers of enhanced pharmacy services from care managers and primary care practice responders. METHODS: An electronic questionnaire was sent to 1648 primary care practices and 600 care managers that work in 76 North Carolina counties containing an enhanced-service community pharmacy. Questionnaires were distributed in January 2017 and responses collected for 7 weeks. The questionnaire collected data on the awareness and perceived value of enhanced pharmacy services, preferred method and level of communication for referral, and barriers to using enhanced services...
July 2018: Journal of the American Pharmacists Association: JAPhA
S Hari, S B Paul, R Vidyasagar, E Dhamija, A D Adarsh, S Thulkar, S Mathur, V Sreenivas, S Sharma, A Srivastava, V Seenu, R Prashad
PURPOSE: To evaluate the role of SWE in characterizing breast masses and ascertain whether additional use of SWE to ultrasound for evaluating BI-RADS 3 and 4a masses could help reduce long-term follow-up and unnecessary biopsies of these suspicious breast masses. MATERIALS AND METHODS: This prospective, cross-sectional study was performed between June 2013 and November 2014. All enrolled patients underwent clinical breast examination, ultrasound, SWE and ultrasound-guided core biopsy of the breast mass...
July 10, 2018: Diagnostic and Interventional Imaging
Jiri Kassa, Christopher M Timperley, Mike Bird, Rebecca L William, A Christopher Green, John E H Tattersall
The effect of three newly developed bispyridinium non-oxime compounds (MB408, MB442, and MB444) on the therapeutic efficacy of a standard antidotal treatment (atropine in combination with the oxime HI-6 or obidoxime) of acute poisoning by two nerve agents (sarin and cyclosarin) in mice was studied. The therapeutic efficacy of atropine in combination with an oxime with or without one of the bispyridinium non-oximes was evaluated by determination of the 24 h LD50 values of the nerve agents studied and by measurement of the survival time after supralethal poisoning...
July 10, 2018: Toxicology
Jin Zhao, Peng Jiang, Ri Qiu, Yingying Ma, Chunhui Wu, Huihui Fu, Huaxin Chen, Fuchao Li
Large scale green tides have bloomed successively in the Yellow Sea since 2007. The floating ecotype of Ulva prolifera, which is responsible for the environmental disaster, drifted a long distance during the blooming time and was exotic to the coastal area. The Yellow Sea green tide can be a potential source to incur bio-invasion. In this study, the distribution pattern and propagule pressure of the floating ecotype was investigated along the Qingdao coastline, which was seriously impacted by the green tide...
July 2018: Harmful Algae
Jonathan M Grund, Candice M Chetty-Makkan, Sibuse Ginindza, Reuben Munyai, Helen Kisbey-Green, Mpho Maraisane, Salome Charalambous
BACKGROUND: South Africa introduced medical male circumcision (MMC) to reduce HIV incidence. Mathematical modeling suggested that targeting MMC services to men aged 20-34 years could provide the most immediate impact on HIV incidence. However the majority of MMCs performed have been among males aged ≤25 years. We evaluated an intervention package to increase MMC uptake among men aged 25-49 years. METHODS: We conducted a pre-post study to compare the proportion of men (aged 25-49 years) presenting for MMC during the formative (Phase 1) and intervention (Phase 2) phases in Ekurhuleni, Johannesburg, South Africa...
July 13, 2018: BMC Public Health
Elyas Hosseinzadeh, Hadi Ravan, Abbas Mohammadi, Rahim Mohammad-Rezaei, Akram Norouzi, Hossein Hosseinzadeh
With the great advances in DNA nanotechnology, scientists have shown interest in developing dynamic nanostructures for theranostic applications, analyte sensing and cargo delivery. Here, we present a specific enzyme-free ultrasensitive platform based on a multilayer coupled signal amplification strategy to quantify miR-21 molecule. The biosensor was integrated based on three signal amplification gadgets, namely a translator-mediated catalytic hairpin assembly (CHA), a multilayer DNA concatemer on the surface of gold decorated magnetic nanoparticle (GMNP), and a DNAzyme-mediated catalytic signal amplification...
June 28, 2018: Biosensors & Bioelectronics
Mackenzie Green, Toby Styles, Timothy Russell, Charif Sada, Ebrima Jallow, Jack Stewart, Otar Lazariashvili, Irina Lubomirova, Ioana Cotlarciuc, Sapna Sharma, Thang S Han, Pankaj Sharma
INTRODUCTION: A wide variety of non-genetic and genetic factors have been shown to associate with increased risk for cerebral venous thrombosis (CVT). However, there is a paucity of risk factor data and conclusions about their impact are often conflicting. Herein, we quantified the associations of non-genetic and genetic risk factors for CVT in adults. MATERIALS AND METHODS: Electronic databases were searched up to January 2017. Meta-analyses were performed (RevMan v5...
July 6, 2018: Thrombosis Research
Huijun Liu, Yilu Xia, Huiyang Fan, Qianru Xu, Shaoting Du, Zhiguo Fang, Huilong Xia
As green and novel solvents, ionic liquids (ILs) are popular in many industries, which may threaten ecosystems. The effects of three imidazolium-based ILs with different alkyl chain lengths, including 1-octyl-3-methylimidazolium chloride ([C8 mim]Cl), 1-decyl-3-methylimidazolium chloride ([C10 mim]Cl), and 1-dodecyl-3-methylimidazolium chloride ([C12 mim]Cl) on growth and photosystem of Arabidopsis thaliana were investigated. Root length, fresh weight, cell membrane permeability, and chlorophyll content of whole plant were significantly affected by ILs...
June 26, 2018: Journal of Hazardous Materials
Doorae Lee, Minhwan Kwon, Yongtae Ahn, Youmi Jung, Seong-Nam Nam, Il-Hwan Choi, Joon-Wun Kang
The aim of this study was to investigate the reactivity of intracellular algogenic organic matter (IOM) with hydroxyl radicals (·OH), a key reaction species in advanced oxidation processes. IOM was extracted from two green algae, Chlamydomonas reinhardtii and Scenedesmus sp., and two blue-green algae, Anabaena sp. and Microcystis aeruginosa using a freeze-thaw method. The second-order rate constants of the extracted IOM with ·OH were determined as 7.95 × 108 MC -1 s-1 (Chlamydomonas reinhardtii), 6.71 × 108 MC -1 s-1 (Scenedesmus sp...
June 30, 2018: Water Research
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