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https://www.readbyqxmd.com/read/29774155/is-de-novo-hepatocellular-carcinoma-after-transjugular-intrahepatic-portosystemic-shunt-increased
#1
A Hüsing-Kabar, T Meister, M Köhler, W Domschke, I Kabar, C Wilms, B Hild, H H Schmidt, H S Heinzow
Background: Portal hypertension is a major complication of liver cirrhosis. Transjugular intrahepatic portosystemic shunt is effective in treatment of portal hypertension. However, decreased parenchymal portal venous flow after transjugular intrahepatic portosystemic shunt insertion favours ischaemic liver injury which has been discussed to induce hepatocarcinogenesis causing hepatocellular cancer. Aim: This study aimed to explore the association between transjugular intrahepatic portosystemic shunt placement and the development of hepatocellular cancer...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29770770/adjustable-diameter-tips-in-the-pediatric-patient-the-constrained-technique
#2
Brandon C Perry, Eric J Monroe, Giridhar Shivaram
Placement of transjugular intrahepatic portosystemic shunt (TIPS) is necessary in children with portal hypertension complicated by variceal bleeding or ascites. However, placement of adult-sized endografts may be problematic due to the smaller anatomy of pediatric patients. On the other hand, placement of fixed diameter smaller stents have the corresponding problem of not accommodating future growth of the child. We describe a novel method to create an adjustable diameter TIPS as a technical solution to these problems...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29758336/grand-rounds-hepatic-manifestations-of-telomere-biology-disorders
#3
REVIEW
Mrinal M Patnaik, Patrick S Kamath, Douglas A Simonetto
Clinical Case A 51 year old Caucasian male was referred for evaluation of variceal bleeding. Laboratory tests were remarkable for mild thrombocytopenia and moderate alkaline phosphatase elevation. Synthetic liver function was well preserved. Abdominal computed tomography scan revealed moderate splenomegaly, gastric varices, and normal hepatic contour. A transjugular liver biopsy was performed revealing findings of nodular regenerative hyperplasia (NRH) with no significant fibrosis or necroinflammatory activity...
May 11, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29756168/transsplenic-splenoportography-and-portal-venous-interventions-in-pediatric-patients
#4
Eric J Monroe, Ethan J Speir, C Matthew Hawkins, Giri Shivaram, Kevin S H Koo, Anne E Gill
BACKGROUND: Data regarding transsplenic portal venous access for diagnostic imaging and endovascular intervention in children are limited, possibly due to concerns regarding high bleeding risks and resultant underutilization. OBJECTIVE: To investigate the safety and utility of transsplenic splenoportography and portal venous interventions in children. MATERIALS AND METHODS: A retrospective review was performed of all pediatric patients undergoing percutaneous transsplenic portal venous access and intervention at two large tertiary pediatric institutions between January 2012 and April 2017 was performed...
May 13, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29738325/automated-low-flow-ascites-pump-in-a-real-world-setting-complications-and-outcomes
#5
Philipp Solbach, Christoph Höner Zu Siederdissen, Freya Wellhöner, Nicolas Richter, Benjamin Heidrich, Henrike Lenzen, Port Kerstin, Katja Hueper, Michael P Manns, Heiner Wedemeyer, Elmar Jaeckel
BACKGROUND AND AIMS: The aim of this study was to investigate the Alfapump, an automated low-flow pump system for the treatment of refractory ascites (RA) as an alternative for repeated large-volume paracentesis in patients with contraindication for placement of a transjugular intrahepatic portosystemic shunt (TIPS) or liver transplantation. MATERIALS AND METHODS: In 21 consecutive patients with RA and contraindication for a placement of a TIPS, the Alfapump was implanted at Hannover Medical School between December 2012 and May 2016...
May 7, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29726061/transjugular-diagnostics-in-acute-liver-failure-including-measurements-of-hepato-central-venous-biomarker-gradients
#6
Martin Chong Wang, Franziska Wandrer, Jerome Schlué, Torsten Voigtländer, Tim Oliver Lankisch, Michael Peter Manns, Heike Bantel, Thomas von Hahn
AIM: Acute liver failure (ALF) as a syndrome of severe liver injury may need urgent liver transplantation and is associated with significant risk of death. Therefore, early outcome prediction and further possibilities to increase accuracy of prognosis scores remain important. METHODS: We examined 30 patients with ALF according to the novel criteria of the Intractable Hepato-Biliary Diseases Study Group who underwent transjugular liver biopsy (TJLB) and investigated the relevance of histology for correct diagnosis and etiology...
May 4, 2018: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29720858/preoperative-elective-transjugular-intrahepatic-portosystemic-shunt-for-cirrhotic-patients-undergoing-abdominal-surgery
#7
REVIEW
Deepanshu Jain, Ejaz Mahmood, Maria V-Bandres, Eyob Feyssa
Despite improvements in the surgical techniques, anesthesia and intensive care, abdominal surgery in patients with cirrhosis remains a challenge. Transjugular intrahepatic portosystemic shunt (TIPS) has been used to manage complications of portal hypertension. Preoperative TIPS (prophylactic) can theoretically improve outcomes in this population. Seven original studies were identified with 24 patients who underwent prophylactic TIPS before abdominal surgery. No perioperative mortality or major abdominal bleeding attributable to portal hypertension was reported for this cohort...
May 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29701339/surgical-treatment-options-of-subclavian-artery-pseudoaneurysms-a-case-report-and-litterature-review
#8
Rita Soares Ferreira, João Monteiro Castro, Frederico Bastos Gonçalves, Rodolfo Abreu, Ricardo Correia, Rui Rodrigues, Carolina Torres, Maria Emília Ferreira
INTRODUCTION: Subclavian artery pseudoaneurysms are rare and occur mostly as a consequence of an inadvertent arterial puncture during central venous catheterization, endovascular therapeutic procedures or after penetrating or blunt trauma. They usually have a late clinical presentation, with pain, swelling or other compressive symptoms. The optimal treatment in this situation is still a matter of debate. The authors describe a case of late presentation of subclavian artery pseudoaneurysm after transjugular hepatic biopsy and discuss the several options for treatment...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29697683/-gastroesophageal-variceal-bleeding-in-cirrhotic-patients-the-possibilities-of-effective-hemostasis
#9
Yu V Khoronko, A E Sarkisov, A A Kiva
AIM: To improve the results of treatment of gastroesophageal variceal bleeding (GEVB) in cirrhotic patients with thrombocytopenia. MATERIAL AND METHODS: A total experience of the clinic includes 338 GEVB patients, endoscopic variceal ligation (EVL) and transjugular intrahepatic portosystemic shunt (TIPS) were performed in 162 and 157 cases respectively. Nevertheless, just the efficacy of initial pharmacological hemostatic therapy was analyzed. RESULTS: Administration of serotonin adipinate 30-50 mg/day during 3-5 days in addition to standard initial therapy allowed us to achieve permanent hemostasis during initial treatment if EVL was impossible...
2018: Khirurgiia
https://www.readbyqxmd.com/read/29692535/t-pa-power-pulse-spray-with-rheolytic-mechanical-thrombectomy-using-cross-sectional-image-guided-portal-vein-access-for-single-setting-treatment-of-subacute-superior-mesenteric-vein-thrombosis
#10
Mubin I Syed, Ryan M Gallagher, Rukan S Ahmed, Azim Shaikh, Edward Roberto, Sumeet Patel
Background: Isolated superior mesenteric vein (SMV) thrombosis is a rare but potentially fatal condition if untreated. Current treatments include transjugular or transhepatic approaches for rheolytic mechanical thrombectomy and subsequent infusions of thrombolytics. Tissue plasminogen activator (t-PA) power-pulse spray can provide benefit in a single setting without thrombolytic infusions. Computed tomography (CT) guidance for portal vein access is underutilized in this setting. Materials and Methods: Case 1 discusses acute SMV thrombosis treated with rheolytic mechanical thrombectomy alone using ultrasound guidance for portal vein access...
January 2018: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29684973/successful-transjugular-intrahepatic-portosystemic-shunt-with-embolization-subsequent-to-endoscopic-variceal-band-ligation-for-bleeding-anorectal-varices
#11
Sang Woo Park, Chung Hwan Jun, Sung Kyu Choi, Hyun Soo Kim, Chang Hwan Park, Jong Sun Rew, Seon Young Park, Eunae Cho, Jae Kyu Kim, Hyoung Ook Kim
Anorectal variceal bleeding is a rare occurrence; however, in such event, it could be fatal due to large size and high blood flow rate of varices. However, to date, there is no standardized treatment modality. Although endoscopic treatment can be provided, in cases of recurrent anorectal variceal bleeding, other therapeutic modalities for hemostasis are necessary. Here, we present a case of 58-year-old female patient with liver cirrhosis, who suffered from massive bleeding of anorectal varices. Endoscopic variceal band ligation was performed for primary hemostasis...
April 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29675358/persistence-of-gastric-or-esophageal-varices-on-final-angiography-increases-transjugular-intrahepatic-portosystemic-shunt-revision-rate-after-polytetrafluoroethylene-covered-stent-shunt-creation
#12
Benjamin Moulin, Olivier Chevallier, Gilles Abdulmalak, Maxime Luu, Marianne Latournerie, Anne Minello, Sophie Gehin, Jean-Pierre Cercueil, Marco Midulla, Romaric Loffroy
Background: To assess the association between final polytetrafluoroethylene (PTFE)-covered stent transjugular intrahepatic portosystemic shunt (TIPS) angiographic parameters and free shunt revision survey. Methods: Series of two comparison groups were generated with persistence of varices or not, the 25th , 50th , and 75th percentile as cutoff for each angle and a 15-mm distance as cutoff for distance D. Kaplan Meier free shunt revision curves were then created and compared with Log Rank test...
March 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29675064/resolution-of-refractory-hepatic-hydrothorax-in-patients-with-hepatitis-c-virus-cirrhosis-after-treatment-with-direct-acting-antiviral-agents
#13
Maged H Hussein, Musthafa Chalikandy Peedikayil, Zamir Ahmed Zamir, Abdulrahman Alfadda
Hepatic hydrothorax (HH) is a transudative pleural effusion that complicates advanced liver cirrhosis. Cases refractory to medical treatment in the form of salt restriction and diuretics are labeled refractory hepatic hydrothorax (RHH) and may require transjugular intrahepatic portosystemic shunts (TIPSS) or even liver transplantation. Renal impairment is common in advanced liver disease, worsens its prognosis, and makes the management of HH more challenging. Successful antiviral therapy reduces some of the complications of cirrhosis secondary to hepatitis C virus (HCV) infection...
April 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29674011/endovascular-transjugular-occlusion-of-congenital-intrahepatic-portosystemic-venous-shunt-using-simultaneous-fluoroscopy-and-transabdominal-ultrasound-guidance-report-of-2-cases
#14
Ujjwal Gorsi, Naveen Kalra, Pankaj Gupta, Karthik Rayasam, Babu Ram Thapa, Hemant Bhagat, Niranjan Khandelwal
Congenital intrahepatic portosystemic venous shunts (CIPVS) are rare anomalies that can be detected before birth or in early infancy or later in life. Symptomatic shunts are treated as they carry high risk of complications like hepatic encephalopathy. Various treatment options include surgery, endovascular embolization, and percutaneous closure devices. We treated 2 infants with CIPVS successfully by endovascular embolization of the shunt using vascular plug through transjugular route. Transabdominal ultrasound guidance in addition to fluoroscopy was used at the time of vascular plug placement...
March 20, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29668568/transjugular-intrahepatic-portosystemic-shunt-insertion-for-the-management-of-portal-hypertension-in-children
#15
Lauren Johansen, Patrick McKiernan, Khalid Sharif, Simon McGuirk
OBJECTIVES: To describe our 20-year experience with transjugular intrahepatic portosystemic shunt (TIPSS) procedures for children with resistant portal hypertension (PHTN). METHODS: Retrospective review of all children that had a TIPSS performed at Birmingham Children's Hospital from 1 January 1995 - 1 January 2015. RESULTS: 40 children underwent 42 attempted TIPSS for resistant PHTN with recurrent variceal bleeding (n = 35), refractory ascites (n = 4), and hypersplenism (n = 1)...
April 17, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29622386/long-term-outcome-of-transjugular-intrahepatic-portosystemic-shunt-for-portal-hypertension-in-autosomal-recessive-polycystic-kidney-disease
#16
Sarah Verbeeck, Djalila Mekhali, David Cassiman, Geert Maleux, Peter Witters
BACKGROUND: Autosomal recessive polycystic kidney disease (ARPKD) with congenital hepatic fibrosis (CHF) causes portal hypertension and its complications. A transjugular intrahepatic portosystemic shunt (TIPSS) could serve as a symptomatic treatment for portal hypertension-related symptoms in these children. AIMS: To study the effect of TIPSS on portal hypertension, liver and kidney function and the long term complications. MATERIALS AND METHODS: We report on 5 children with CHF treated with a TIPSS to manage severe portal hypertension related symptoms...
March 15, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29613983/in-vivo-abdominal-magnetic-resonance-elastography-for-the-assessment-of-portal-hypertension-before-and-after-transjugular-intrahepatic-portosystemic-shunt-implantation-erratum
#17
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29610668/hcfc-123-induced-toxic-hepatitis-and-death-at-a-korean-fire-extinguisher-manufacturing-facility-a-case-series
#18
Mu Young Shin, Jong Soo Park, Hae Dong Park, Jihye Lee
Background: Exposure to sustained high concentrations of HCFC-123 is known to be hepatotoxic. We report two simultaneous cases of toxic hepatitis related to exposure to 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123), a common refrigerant, at a Korean fire extinguisher manufacturing facility. Case presentation: Patients A and B were men aged 21 and 22 years, respectively, with no notable medical histories. They had recently started working for a manufacturer of fire extinguishers...
2018: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29609068/cost-effectiveness-of-early-insertion-of-transjugular-intrahepatic-portosystemic-shunts-for-recurrent-ascites
#19
Nicole T Shen, Yecheskel Schneider, Stephen E Congly, Russell E Rosenblatt, Yunseok Namn, Brett E Fortune, Arun Jesudian, Robert S Brown
BACKGROUND & AIMS: Treatment options for recurrent ascites resulting from decompensated cirrhosis include serial large volume paracentesis and albumin infusion (LVP+A) or insertion of a transjugular intrahepatic portosystemic shunt (TIPS). Insertion of TIPSs with covered stents during early stages of ascites (early TIPS, defined as 2 LVPs within the past 3 weeks and less than 6 LVPs in the prior 3 months) significantly improves chances of survival and reduces complications of cirrhosis compared to LVP+A...
March 30, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29606895/hepatic-encephalopathy-current-challenges-and-future-prospects
#20
REVIEW
Mirashini Swaminathan, Mark Alexander Ellul, Timothy Js Cross
Hepatic encephalopathy (HE) is a common complication of liver dysfunction, including acute liver failure and liver cirrhosis. HE presents as a spectrum of neuropsychiatric symptoms ranging from subtle fluctuating cognitive impairment to coma. It is a significant contributor of morbidity in patients with liver disease. HE is observed in acute liver failure, liver bypass procedures, for example, shunt surgry and transjugular intrahepatic portosystemic shunt, and cirrhosis. These are classified as Type A, B and C HE, respectively...
2018: Hepatic Medicine: Evidence and Research
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