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Osteoporosis and falls

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https://www.readbyqxmd.com/read/28739416/comparison-of-non-invasive-assessments-of-strength-of-the-proximal-femur
#1
Fjola Johannesdottir, Erica Thrall, John Muller, Tony M Keaveny, David L Kopperdahl, Mary L Bouxsein
It is not clear which non-invasive method is most effective for predicting strength of the proximal femur in those at highest risk of fracture. The primary aim of this study was to compare the abilities of dual energy X-ray absorptiometry (DXA)-derived aBMD, quantitative computed tomography (QCT)-derived density and volume measures, and finite element analysis (FEA)-estimated strength to predict femoral failure load. We also evaluated the contribution of cortical and trabecular bone measurements to proximal femur strength...
July 21, 2017: Bone
https://www.readbyqxmd.com/read/28737630/first-in-the-nation-one-unit-s-journey-to-achieving-fragility-fracture-certification
#2
Audry McDonald, Samantha Church, Laura Hixon, Linda Vo, Martha Sleutel
Osteoporosis is related to more than 2 million fractures and $19 billion in healthcare costs each year (). A fragility fracture (FF) is a low-energy fracture of the distal radius, proximal humerus, ankle, or proximal femur (hip) from minimal trauma such as a fall from a standing height. In addition to cost, FFs often result in the loss of independence and productivity (). In 2015, our orthopaedic unit received the first certification ever awarded for FFs. Fragility fracture certification is a new certification demonstrating that a healthcare facility complies with national patient care standards and uses evidence-based practice guidelines to deliver quality outcomes...
July 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28733716/osteosarcopenia-where-bone-muscle-and-fat-collide
#3
REVIEW
H P Hirschfeld, R Kinsella, G Duque
As the world's population ages, the prevalence of chronic diseases increases. Sarcopenia and osteoporosis are two conditions that are associated with aging, with similar risk factors that include genetics, endocrine function, and mechanical factors. Additionally, bone and muscle closely interact with each other not only anatomically, but also chemically and metabolically. Fat infiltration, a phenomenon observed in age-related bone and muscle loss, is highly prevalent and more severe in sarcopenic and osteoporotic subjects...
July 22, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28724392/a-prospective-study-assessing-agreement-and-reliability-of-a-geriatric-evaluation
#4
Isabella Locatelli, Stéfanie Monod, Jacques Cornuz, Christophe J Büla, Nicolas Senn
BACKGROUND: The present study takes place within a geriatric program, aiming at improving the diagnosis and management of geriatric syndromes in primary care. Within this program it was of prime importance to be able to rely on a robust and reproducible geriatric consultation to use as a gold standard for evaluating a primary care brief assessment tool. The specific objective of the present study was thus assessing the agreement and reliability of a comprehensive geriatric consultation...
July 19, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28695804/effects-of-enhanced-exercise-and-combined-vitamin-d-and-calcium-supplementation-on-muscle-strength-and-fracture-risk-in-postmenopausal-chinese-women
#5
Yu Xue, Yingying Hu, Ou Wang, Chunyan Wang, Guiyan Han, Qiang Shen, Hongyue Deng, Yan Jiang, Mei Li, Weibo Xia, Xiaoping Xing, Ling Xu
Objective To observe the effects of enhanced exercise and combined vitamin D and calcium supplementation on muscular strength and fracture occurrence in postmenopausal women with a high risk of osteoporosis.Methods Totally 614 postmenopausal women at high risk factors of osteoporosis were enrolled in Dongcheng district of Beijing and randomized into four groups:group A(control group,n=173),group B(regular Tai Chi exercise,n=171),group C(calcium 600 mg/d+VitD3 800 U/d,n=139),and group D[calcium 600 mg/d+25 hydroxyl vitamin D(25OHD) 0...
June 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28687055/psychometric-properties-of-the-swedish-version-of-the-falls-efficacy-scale-international-for-older-adults-with-osteoporosis-self-reported-balance-deficits-and-fear-of-falling
#6
Alexandra Halvarsson, Agneta Ståhle
PURPOSE: Investigate the psychometric properties of the Swedish version of the Falls Efficacy Scale-International (FES-I). METHOD: Cross-sectional study. Community-dwelling older adults with self-reported balance deficits and fear of falling were recruited from an ongoing randomised controlled study to evaluate the psychometric properties of the FES-I using Rasch model analysis. RESULTS: The Rasch model analysis revealed good category function, the questionnaire measured one dimension with an explained variance of 68...
July 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28661865/health-benefits-of-tai-chi-what-is-the-evidence
#7
REVIEW
Patricia Huston, Bruce McFarlane
OBJECTIVE: To summarize the evidence on the health benefits of tai chi. SOURCES OF INFORMATION: A literature review was conducted on the benefits of tai chi for 25 specific conditions, as well as for general health and fitness, to update a 2014 review of systematic reviews. Systematic reviews and recent clinical trials were assessed and organized into 5 different groups: evidence of benefit as excellent, good, fair, or preliminary, or evidence of no direct benefit...
November 2016: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28645976/a-combined-randomised-and-observational-study-of-surgery-for-fractures-in-the-distal-radius-in-the-elderly-crossfire-a-study-protocol
#8
Ian A Harris, Justine M Naylor, Andrew Lawson, Rachelle Buchbinder, Rebecca Ivers, Zsolt Balogh, Paul Smith, Rajat Mittal, Wei Xuan, Kirsten Howard, Arezoo Vafa, Piers Yates, Bertram Rieger, Geoff Smith, Ilia Elkinson, Woosung Kim, Mellick Chehade, Jai Sungaran, Kim Latendresse, James Wong, Sameer Viswanathan, Martin Richardson, Kush Shrestha, Herwig Drobetz, Phong Tran, Jeremy Loveridge, Richard Page, Raphael Hau, Roger Bingham, Jonathan Mulford, Ian Incoll
Fractures of the distal radius are common and occur in all age groups. The incidence is high in older populations due to osteoporosis and increased falls risk. Considerable practice variation exists in the management of distal radius fractures in older patients ranging from closed reduction with cast immobilisation to open reduction with plate fixation. Plating is currently the most common surgical treatment. While there is evidence showing no significant advantage for some forms of surgical fixation over conservative treatment, and no difference between different surgical techniques, there is a lack of evidence comparing two of the most common treatments used: closed reduction and casting versus plating...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28643265/factors-associated-with-high-24-month-persistence-with-denosumab-results-of-a-real-world-non-interventional-study-of-women-with-postmenopausal-osteoporosis-in-germany-austria-greece-and-belgium
#9
A Fahrleitner-Pammer, N Papaioannou, E Gielen, M Feudjo Tepie, C Toffis, I Frieling, P Geusens, P Makras, E Boschitsch, J Callens, A D Anastasilakis, C Niedhart, H Resch, L Kalouche-Khalil, P Hadji
Persistence with osteoporosis therapy is vital for fracture prevention. This non-interventional study of postmenopausal women receiving denosumab in Germany, Austria, Greece, and Belgium found that persistence with denosumab remains consistently high after 24 months in patients at high risk of fracture. PURPOSE: Continued persistence with osteoporosis therapy is vital for fracture prevention. This non-interventional study of clinical practice evaluated medication-taking behavior of postmenopausal women receiving denosumab in Germany, Austria, Greece, and Belgium and factors influencing persistence...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28638514/internal-medicine-residents-ambulatory-management-of-core-geriatric-conditions
#10
Kathryn E Callahan, Lindsay A Wilson, Juliessa M Pavon, James F Lovato, Hal H Atkinson, Jan Busby-Whitehead, Thomas Dalton, Mitchell T Heflin, Patricia Iverson, Janice S Lawlor, Justin Marsden, William P Moran, Ellen Roberts, Jeff D Williamson
BACKGROUND: Adults aged 65 years and older account for more than 33% of annual visits to internal medicine (IM) generalists and specialists. Geriatrics experiences are not standardized for IM residents. Data are lacking on IM residents' continuity experiences with older adults and competencies relevant to their care. OBJECTIVE: To explore patient demographics and the prevalence of common geriatric conditions in IM residents' continuity clinics. METHODS: We collected data on age and sex for all IM residents' active clinic patients during 2011-2012...
June 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28595648/investigation-and-management-of-osteoporosis-in-aged-trauma-patients-a-treatment-algorithm-adapted-to-the-german-guidelines-for-osteoporosis
#11
Carl Neuerburg, Lena Mittlmeier, Ralf Schmidmaier, Christian Kammerlander, Wolfgang Böcker, Wolf Mutschler, Ulla Stumpf
BACKGROUND: Osteoporosis-associated fractures are of increasing importance in trauma surgery. Systematic diagnostics and treatment of osteoporosis during a hospital stay, however, remain inadequate. Therefore, a specific algorithm for diagnosing and treating osteoporosis in trauma surgery patients was developed based on the DVO (German Osteology Society) guideline for osteoporosis from 2014. METHODS: In a first step, the individuals' age and risk profile for osteoporosis is identified considering specific fractures indicating osteoporosis and risk factors assessed by a specific questionnaire...
June 8, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28593447/predictors-of-near-term-fracture-in-osteoporotic-women-aged-%C3%A2-65%C3%A2-years-based-on-data-from-the-study-of-osteoporotic-fractures
#12
D Weycker, J Edelsberg, R Barron, M Atwood, G Oster, D B Crittenden, A Grauer
Using data from the Study of Osteoporotic Fractures (SOF), several clinical characteristics predictive of near-term (1-year) risk of hip and non-vertebral fracture among elderly osteoporotic women were identified, and a subset of those for hip fracture was incorporated into a risk assessment tool. Additional research is needed to validate study findings. INTRODUCTION: While several risk factors are known to contribute to long-term fracture risk in women with osteoporosis, factors predicting fracture risk over a shorter time horizon, such as over a 1-year period, are less well-established...
June 7, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28586603/evaluating-the-risk-of-osteoporosis-through-bone-mass-density
#13
Sayeeda Amber Sayed, Asif Khaliq, Ashar Mahmood
BACKGROUND: Osteoporosis is a bone disorder, characterized by loss of bone mass density. Osteoporosis affects more than 30% of post-menopausal women. Osteoporosis is often associated with restricted body movement, pain and joint deformities. Early identification and early intervention can help in reducing these complications. The primary objective of this study was to estimate the burden of Osteoporosis in Urban setting of Sindh among women of different age groups and to access the effect of different protective measures that can reduce the risk of Osteoporosis...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28585054/the-effects-of-person-centered-or-other-supportive-interventions-in-older-women-with-osteoporotic-vertebral-compression-fractures-a-systematic-review-of-the-literature
#14
REVIEW
H K Svensson, L -E Olsson, T Hansson, J Karlsson, E Hansson-Olofsson
Vertebral compression fracture (VCF) is a common fragility fracture and the starting point of a lasting, painful, disabling condition. The aim was to summarize evidence of person-centered/non-medical interventions supporting women with VCF. Results show small numbers of studies with only probable effect on function, pain, QoL, fear of falling, and psychological symptoms. The vertebral compression fracture (VCF) caused by osteoporosis is the third most common fragility fracture worldwide. Previously, it was believed that the pain caused by VCF was self-subsiding within weeks or a few months post-fracture...
June 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28580386/hospitalizations-for-osteoporosis-related-fractures-economic-costs-and-clinical-outcomes
#15
Derek Weycker, Xiaoyan Li, Rich Barron, Rebecca Bornheimer, David Chandler
BACKGROUND: Osteoporotic fractures frequently require inpatient care, and are associated with elevated risks of morbidity, mortality, and re-hospitalization. A comprehensive evaluation of healthcare costs, resource utilization, and outcomes associated with osteoporosis (OP)-related fractures treated in US hospitals was undertaken. METHODS: A retrospective analysis using the Premier Perspective Database (2010 - 2013) was conducted. Study population comprised patients aged ≥ 50 years hospitalized with a principal diagnosis of a closed or pathologic fracture commonly associated with OP; the first qualifying hospitalization was designated the "index admission"...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28575126/gait-dynamics-to-optimize-fall-risk-assessment-in-geriatric-patients-admitted-to-an-outpatient-diagnostic-clinic
#16
Lisette H J Kikkert, Maartje H de Groot, Jos P van Campen, Jos H Beijnen, Tibor Hortobágyi, Nicolas Vuillerme, Claudine C J Lamoth
Fall prediction in geriatric patients remains challenging because the increased fall risk involves multiple, interrelated factors caused by natural aging and/or pathology. Therefore, we used a multi-factorial statistical approach to model categories of modifiable fall risk factors among geriatric patients to identify fallers with highest sensitivity and specificity with a focus on gait performance. Patients (n = 61, age = 79; 41% fallers) underwent extensive screening in three categories: (1) patient characteristics (e...
2017: PloS One
https://www.readbyqxmd.com/read/28574525/severe-right-hip-pain
#17
Anthony P Trace, Kimberly Hoang, Joseph S McMonagle
While this patient had osteoporosis, she hadn't experienced any recent trauma or falls that would explain her pain.
June 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/28553228/how-general-practitioners-and-their-patients-adhere-to-osteoporosis-management-a-follow-up-survey-among-czech-general-practitioners
#18
Magda Vytrisalova, Tereza Touskova, Leos Fuksa, Roman Karascak, Vladimir Palicka, Svatopluk Byma, Jan Stepan
Introduction: General practitioners (GPs) are key participants in osteoporosis (OP) management. The aim was to evaluate their adherence to lege artis management of the disease, potential barriers, and to discuss differences observed in comparison with the baseline survey carried out in 2007; the focus was on secondary prevention. Methods: On behalf of two professional associations, 2-round postal survey among randomly selected GPs (>1/4 of all Czech GPs) was performed in 2014. The questionnaire covered areas concerning GP's role in the fight against OP, knowledge about OP, management of OP-related fractures, barriers to the management of OP, system- and patient-related in particular, and availability and use of information sources...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28549839/vitamin-b12-deficiency-might-be-related-to-sarcopenia-in-older-adults
#19
Esra Ates Bulut, Pinar Soysal, Ali Ekrem Aydin, Ozge Dokuzlar, Suleyman Emre Kocyigit, Ahmet Turan Isik
Sarcopenia and dynapenia are related to repeated falls, mobility restriction, depression, frailty, increased mortality and morbidity. The aim of this study is to evaluate the relationship between vitamin B12 deficiency and sarcopenia in older adults. 403 patients, who attended to outpatient clinic and underwent comprehensive geriatric assessment, were included study. All cases' skeletal muscle mass (SMM), walking speed and hand grip strength were recorded by bioimpedance, 4meter walking test and hand dynamometer respectively...
September 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28543940/greater-gains-in-spine-and-hip-strength-for-romosozumab-compared-to-teriparatide-in-postmenopausal-women-with-low-bone-mass
#20
T M Keaveny, D B Crittenden, M A Bolognese, H K Genant, K Engelke, B Oliveri, J P Brown, B L Langdahl, C Yan, A Grauer, C Libanati
Romosozumab is a monoclonal antibody that inhibits sclerostin and has been shown to reduce the risk of fractures within 12 months. In a Phase II, randomized, placebo-controlled clinical trial of treatment-naïve postmenopausal women with low bone mass, romosozumab increased BMD at the hip and spine by the dual effect of increasing bone formation and decreasing bone resorption. In a substudy of that trial, which included placebo and teriparatide arms, here we investigated whether those observed increases in BMD also resulted in improvements in estimated strength, as assessed by finite element analysis...
May 25, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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