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Osteoporosis and falls

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https://www.readbyqxmd.com/read/29770323/dental-mesenchymal-stem-cell-based-translational-regenerative-dentistry-from-artificial-to-biological-replacement
#1
REVIEW
Mona K Marei, Rania M El Backly
Dentistry is a continuously changing field that has witnessed much advancement in the past century. Prosthodontics is that branch of dentistry that deals with replacing missing teeth using either fixed or removable appliances in an attempt to simulate natural tooth function. Although such "replacement therapies" appear to be easy and economic they fall short of ever coming close to their natural counterparts. Complications that arise often lead to failures and frequent repairs of such devices which seldom allow true physiological function of dental and oral-maxillofacial tissues...
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29767227/effect-of-a-balance-training-programme-on-postural-balance-aerobic-capacity-and-frequency-of-falls-in-women-with-osteoporosis-a-randomized-controlled-trial
#2
Ibolya Miko, Imre Szerb, Anna Szerb, Tamas Bender, Gyula Poor
OBJECTIVE: To investigate the effect of a 12-month complex balance-training programme on static and dynamic postural balance, aerobic capacity and frequency of falls in women with established osteoporosis. DESIGN: Randomized controlled trial in which the intervention group was assigned a 12-month exercise programme (3 times a week for 30 min) and the control group had no intervention. SUBJECTS: A total of 100 osteoporotic women with at least one previous fracture...
May 16, 2018: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29767225/effect-of-balance-training-on-the-falling-in-osteoporosis-patients-a-systematic-review-and-meta-analysis
#3
Xin Zhou, Hui Ding, Xiaoping Shen, Zingliang Lei
BACKGROUND: Balance training may be beneficial for patients with osteoporosis, although current results are inconclusive. The aim of this systematic review and meta-analysis was to explore the effect of balance training on falls in patients with osteoporosis. METHODS: PubMed, Embase, Web of Science, EBSCO, and Cochrane Library databases were systematically searched. Randomized controlled trials (RCTs) assessing the effect of balance training vs usual activities on falls in patients with osteoporosis were included...
May 16, 2018: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29740928/incidence-timing-and-impact-of-comorbidity-on-second-hip-fracture-a-population-based-study
#4
Lara Harvey, Barbara Toson, Rebecca Mitchell, Henry Brodaty, Brian Draper, Jacqueline Close
BACKGROUND: To quantify the incidence and timing of second hip fracture, and to evaluate the relative impact of comorbidities on risk of second hip fracture. METHODS: Hospitalization records for individuals aged ≥65, admitted to a New South Wales hospital for fall-related hip fracture between 1 January 2005 and 31 December 2009 were linked. Comorbidities were identified from the records using a 1-year look-back period. To calculate second hip fracture rates, individuals were followed until death, fracture or end of study period (31 December 2012)...
May 8, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29738597/fall-risk-assessment-metrics-for-elderly-patients-with-hip-fractures
#5
Christos Th Vottis, Evanthia Mitsiokapa, Vasilios G Igoumenou, Panayiotis D Megaloikonomos, Ioannis P Galanopoulos, George Georgoudis, Panayiotis Koulouvaris, Panayiotis J Papagelopoulos, Andreas F Mavrogenis
The most common surgery performed by orthopedic surgeons likely involves that for hip fractures. The incidence of hip fractures is anticipated to rise in the coming decades. Hip fractures most commonly occur in elderly women with osteoporosis after a fall from standing position. In an effort to reduce the incidence, improve the postoperative care, and accelerate the rehabilitation of hip fractures, it is important to evaluate the fall risk of these patients, as it is an objective indication of their level of physical activity...
May 8, 2018: Orthopedics
https://www.readbyqxmd.com/read/29727228/osteosarcopenia
#6
James Paintin, Cyrus Cooper, Elaine Dennison
Osteosarcopenia is a newly described syndrome that describes the co-existence of osteoporosis and sarcopenia, two chronic musculoskeletal conditions associated with ageing. Osteoporosis, a condition of low bone mass and micro-architectural deterioration of bone, and sarcopenia, the loss of muscle mass, strength and function, often co-exist in a frail subset of the elderly population, leading to significantly worsened outcomes than seen in either condition alone. These include a greater risk of falls, fractures and institutionalization, and significant socioeconomic costs...
May 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29710141/interventions-to-prevent-falls-in-community-dwelling-older-adults-us-preventive-services-task-force-recommendation-statement
#7
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Aaron B Caughey, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Martha Kubik, Seth Landefeld, Carol M Mangione, Michael Pignone, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Falls are the leading cause of injury-related morbidity and mortality among older adults in the United States. In 2014, 28.7% of community-dwelling adults 65 years or older reported falling, resulting in 29 million falls (37.5% of which needed medical treatment or restricted activity for a day or longer) and an estimated 33 000 deaths in 2015. Objective: To update the 2012 US Preventive Services Task Force (USPSTF) recommendation on the prevention of falls in community-dwelling older adults...
April 24, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29704027/implementation-of-the-western-australian-osteoporosis-model-of-care-a-fracture-liaison-service-utilising-emergency-department-information-systems-to-identify-patients-with-fragility-fracture-to-improve-current-practice-and-reduce-re-fracture-rates-a-12-month
#8
C A Inderjeeth, W D Raymond, A M Briggs, E Geelhoed, D Oldham, D Mountain
Fracture liaison service linked to an emergency department database effectively identifies patients with OP, improves best practice care, reduces recurrent fractures, and improves quality of life (QoL). The next step is to establish cost-effectiveness. This should be seen as the standard model of care. INTRODUCTION: The Western Australian Osteoporosis Model of Care recommends implementation of a fracture liaison service (FLS) to manage patients with minimal trauma fractures (MTFs). This study evaluates the efficacy of a FLS linked to a tertiary hospital emergency department information system (EDIS) in reducing recurrent fractures...
April 27, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29701911/dysmobility-syndrome-independently-increases-fracture-risk-in-the-osteoporotic-fractures-in-men-mros-prospective-cohort-study
#9
Bjoern Buehring, Karen E Hansen, Brian L Lewis, Steven R Cummings, Nancy E Lane, Neil Binkley, Kristine E Ensrud, Peggy M Cawthon
We proposed the term "dysmobility syndrome" (DS) to identify individuals with impaired musculoskeletal health, a risk factor for falls and fractures. Whether DS is associated with increased risk of incident fracture is unknown. The "Osteoporotic Fractures in Men" study enrolled 5994 men ages ≥65 years, between March 2000 and April 2002. We used baseline data to determine whether DS increased fracture risk, independent of FRAX. Men met DS criteria at baseline if they had ≥3 of the following: appendicular lean mass/height2 <7...
April 27, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29691686/-becoming-older-with-axial-spondyloarthritis
#10
REVIEW
U Kiltz, X Baraliakos, B Buehring, J Braun
The combination of physiological age-related changes (e. g. reduction in muscle mass and function, reduction in organ function and degenerative changes in joints) and disease-specific changes of ankylosing spondylitis (AS), make older AS patients vulnerable for additional diseases. In this patient population various processes lead to a reduction in physical function, changes in posture, osteoporosis and sarcopenia, which then can result in falls and fractures, especially vertebral fractures. Mortality is increased in patients with AS, particularly in men due to an increase in cardiovascular mortality...
April 24, 2018: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29685453/bone-and-glucocorticoids
#11
Karine Briot
Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the most frequent cause of osteoporosis in young people. Bone loss and fracture risk increase rapidly after the initiation of corticosteroid therapy and are proportional to dose and treatment duration. The increase in fracture risk is not fully assessed by bone mineral density measurement, as it is also related to impaired bone quality and increased risk of falls. Prevention should be considered in all patients beginning corticosteroid therapy, especially as the underlying inflammation in itself impairs bone quality...
April 20, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29677309/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-community-dwelling-adults-us-preventive-services-task-force-recommendation-statement
#12
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Aaron B Caughey, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Martha Kubik, Seth Landefeld, Carol M Mangione, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Because of the aging population, osteoporotic fractures are an increasingly important cause of morbidity and mortality in the United States. Approximately 2 million osteoporotic fractures occurred in the United States in 2005, and annual incidence is projected to increase to more than 3 million fractures by 2025. Within 1 year of experiencing a hip fracture, many patients are unable to walk independently, more than half require assistance with activities of daily living, and 20% to 30% of patients will die...
April 17, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29675770/sports-participation-and-fracture-in-older-australian-men
#13
Kara L Holloway-Kew, David J Moloney, Gosia Bucki-Smith, Natalie K Hyde, Sharon L Brennan-Olsen, Elizabeth N Timney, Amelia G Dobbins, Julie A Pasco
Older men who participated in a sporting activity were less likely to sustain any fracture or major osteoporotic fracture over a 6-year follow-up period. PURPOSE: Regular weight-bearing physical activity can reduce fracture risk through an increase in bone strength, as well as reducing falls risk by improving muscle strength and balance. In this study, we aimed to determine whether a specific type of physical activity, sports participation, reduces fracture risk in older Australian men...
April 19, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29615028/effect-of-a-resistance-and-balance-exercise-programme-for-women-with-osteoporosis-and-vertebral-fracture-study-protocol-for-a-randomized-controlled-trial
#14
Brita Stanghelle, Hege Bentzen, Lora Giangregorio, Are Hugo Pripp, Astrid Bergland
BACKGROUND: Osteoporotic vertebral fractures are common, and are associated with reduced functioning and health related quality of life. The primary aims of this randomized controlled trial are to examine the immediate and long-term effects of a 12-weeks supervised group exercise programme on habitual walking speed in older women with osteoporosis and a history of vertebral fracture. The secondary aims are to examine the immediate and long-term effects of the exercise program on physical fitness, fear of falling and quality of life...
April 3, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29603673/numerical-investigation-of-the-effect-of-bone-cement-porosity-on-osteoporotic-femoral-augmentation
#15
María E Santana Artiles, Demetrios T Venetsanos
Femoroplasty is the injection of bone cement into the proximal femur, enhances the bone load capacity and is typically applied to osteoporotic femora. To minimize the required injected volume of bone cement and maximize the load capacity enhancement, an optimization problem must be solved, where the modulus of elasticity of the augmented bone is a key element. This paper, through the numerical investigation of a fall on the greater trochanter of an osteoporotic femur, compares different ways to calculate this modulus and introduces an approach, based on the concept of bone cement porosity, which provides results statistically similar to those obtained with other considerations...
March 30, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29595401/epidemiological-profile-of-thoracolumbar-fracture-tlf-over-a-period-of-10-years-in-tianjin-china
#16
Bo Li, Chao Sun, Chenxi Zhao, Xue Yao, Yan Zhang, Huiquan Duan, Jian Hao, Xing Guo, Baoyou Fan, Guangzhi Ning, Shiqing Feng
CONTEXT/OBJECTIVE: The objective of the research was to illustrate the epidemiology profile of thoracolumbar fracture (TLF) in Tianjin Medical University General Hospital, China, from 2006-2015. DESIGN: Hospital-based retrospective study. SETTING: Tianjin Medical University General Hospital. METHODS: Medical records of inpatient patients with TLF from 1 January 2006 to December 2015 were collected. Detailed information on epidemiological characters were analyzed based on the medical records suffering from TLF from T11-L2 level, including incidence, age and sex, marital, occupation, etiology and fracture type, types of injuries...
March 29, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29558034/effect-of-physical-activity-on-the-sequelae-of-osteoporosis-in-female-residents-of-residential-care-facilities
#17
Agnieszka J Nawrat-Szołtysik, Anna Polak, Andrzej Małecki, Laura Piejko, Dominika Grzybowska-Ganszczyk, Michał Kręcichwost, Józef Opara
BACKGROUND: Osteoporosis is one of the most common diseases that develop with age and cause high morbidity and mortality among elderly people. OBJECTIVES: This study was set out to evaluate the influence of a program of modified Sinaki exercises, Nordic walking (NW) and a combination of these physical activities on people with osteoporosis. MATERIAL AND METHODS: A sample consisting of 91 women aged 65-98 years living in residential care facilities was randomized into 4 groups...
March 20, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29549679/trauma-in-elderly-patients-a-study-of-prevalence-comorbidities-and-gender-differences
#18
M Gioffrè-Florio, L M Murabito, C Visalli, F P Pergolizzi, F Famà
AIM: Trauma, in geriatric patients, increases with age, and is a leading cause of disability and institutionalization, resulting in morbidity and mortality. The aim of our study was to analyse the prevalence of trauma, the related risk factors, mortality and sex differences in the prevalence in a geriatric population. PATIENTS AND METHOD: We observed 4,554 patients (≥65 years) with home injuries or car accidents. Patients were evaluated with ISS (Injury Severity Score) and major trauma with ATLS (Advanced Trauma Life Support)...
January 2018: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29548300/the-combined-effect-of-parathyroid-hormone-1-34-and-whole-body-vibration-exercise-in-the-treatment-of-osteoporosis-pavos-study-protocol-for-a-randomized-controlled-trial
#19
Ditte Beck Jepsen, Jesper Ryg, Niklas Rye Jørgensen, Stinus Hansen, Tahir Masud
BACKGROUND: PaVOS is a randomized controlled trial (RCT) which aims to address the use of whole-body vibration exercise (WBV) in combination with parathyroid hormone 1-34 fragment teriparatide (PTH 1-34) treatment in patients with osteoporosis. PTH 1-34 is an effective but expensive anabolic treatment for osteoporosis. WBV has been found to stimulate muscle and bone growth. Animal studies have shown a beneficial effect on bone when combining PTH 1-34 with mechanical loading. A combined treatment with PTH 1-34 and WBV may potentially have beneficial effects on bone and muscles, and reduce fracture risk...
March 16, 2018: Trials
https://www.readbyqxmd.com/read/29526781/comparison-of-femoral-strength-and-fracture-risk-index-derived-from-dxa-based-finite-element-analysis-for-stratifying-hip-fracture-risk-a-cross-sectional-study
#20
Shuman Yang, Yunhua Luo, Lang Yang, Enrico Dall'Ara, Richard Eastell, Andrew L Goertzen, Eugene V McCloskey, William D Leslie, Lisa M Lix
BACKGROUND: Dual-energy X-ray absorptiometry (DXA)-based finite element analysis (FEA) has been studied for assessment of hip fracture risk. Femoral strength (FS) is the maximum force that the femur can sustain before its weakest region reaches the yielding limit. Fracture risk index (FRI), which also considers subject-specific impact force, is defined as the ratio of von Mises stress induced by a sideways fall to the bone yield stress over the proximal femur. We compared risk stratification for prior hip fracture using FS and FRI derived from DXA-based FEA...
May 2018: Bone
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