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https://www.readbyqxmd.com/read/28801498/comparison-of-veterinary-drugs-and-veterinary-homeopathy-part-1
#1
P Lees, L Pelligand, M Whiting, D Chambers, P-L Toutain, M L Whitehead
For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of veterinary therapeutics. There remains today a much smaller, but significant, use of homeopathy by veterinary surgeons. Homeopathic products are sometimes administered when conventional drug therapies have not succeeded, but are also used as alternatives to scientifically based therapies and licensed products...
August 12, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28800075/biofilms-in-endodontics-current-status-and-future-directions
#2
REVIEW
Prasanna Neelakantan, Monica Romero, Jorge Vera, Umer Daood, Asad U Khan, Aixin Yan, Gary Shun Pan Cheung
Microbiota are found in highly organized and complex entities, known as biofilms, the characteristics of which are fundamentally different from microbes in planktonic suspensions. Root canal infections are biofilm mediated. The complexity and variability of the root canal system, together with the multi-species nature of biofilms, make disinfection of this system extremely challenging. Microbial persistence appears to be the most important factor for failure of root canal treatment and this could further have an impact on pain and quality of life...
August 11, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28797402/the-identification-of-calcified-coronary-plaque-is-associated-with-initiation-and-continuation-of-pharmacological-and-lifestyle-preventive-therapies-a-systematic-review-and-meta-analysis
#3
Ankur Gupta, Emily Lau, Ravi Varshney, Edward A Hulten, Michael Cheezum, Marcio S Bittencourt, Michael J Blaha, Nathan D Wong, Roger S Blumenthal, Matthew J Budoff, Craig A Umscheid, Khurram Nasir, Ron Blankstein
OBJECTIVES: The aim of this study was to assess the odds of initiation or continuation of pharmacological and lifestyle preventive therapies in patients with nonzero versus zero coronary artery calcium (CAC) score detected on cardiac computed tomography. BACKGROUND: Detection of calcified coronary plaque could serve as a motivational tool for physicians and patients to intensify preventive therapies. METHODS: We searched PubMed, EMBASE (Excerpta Medica database), Web of Science, Cochrane CENTRAL (Cochrane central register of controlled trials), ClinicalTrials...
August 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28792957/assessing-the-impact-of-healthcare-research-a-systematic-review-of-methodological-frameworks
#4
Samantha Cruz Rivera, Derek G Kyte, Olalekan Lee Aiyegbusi, Thomas J Keeley, Melanie J Calvert
BACKGROUND: Increasingly, researchers need to demonstrate the impact of their research to their sponsors, funders, and fellow academics. However, the most appropriate way of measuring the impact of healthcare research is subject to debate. We aimed to identify the existing methodological frameworks used to measure healthcare research impact and to summarise the common themes and metrics in an impact matrix. METHODS AND FINDINGS: Two independent investigators systematically searched the Medical Literature Analysis and Retrieval System Online (MEDLINE), the Excerpta Medica Database (EMBASE), the Cumulative Index to Nursing and Allied Health Literature (CINAHL+), the Health Management Information Consortium, and the Journal of Research Evaluation from inception until May 2017 for publications that presented a methodological framework for research impact...
August 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28792680/transcriptomic-basis-of-genome-by-genome-variation-in-a-legume-rhizobia-mutualism
#5
Liana T Burghardt, Joseph Guhlin, Chan Lan Chun, Junqi Liu, Michael J Sadowsky, Robert M Stupar, Nevin D Young, Peter Tiffin
In the legume-rhizobia mutualism, the benefit each partner derives from the other depends on the genetic identity of both host and rhizobial symbiont. To gain insight into the extent of genome x genome interactions on hosts at the molecular level and to identify potential mechanisms responsible for the variation, we examined host gene expression within nodules (the plant organ where the symbiosis occurs) of four genotypes of Medicago truncatula grown with either Ensifer meliloti or E. medicae symbionts. These host x symbiont combinations show significant variation in nodule and biomass phenotypes...
August 9, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28771922/mental-health-nurse-prescribing-a-qualitative-systematic-review
#6
REVIEW
Michelle Cleary, Rachel Kornhaber, Jan Sayers, Richard Gray
The aim of the present qualitative, systematic review was to identify and summarize qualitative research that focussed on mental health nurse prescribing, synthesize findings, and outline key themes discerned. In November 2016, a systematic search was conducted for primary studies of the electronic databases PubMed, Excerpta Medica, (Embase), Cumulative Index to Nursing and Allied Health Literature, Scopus, and PsycINFO. Of the 101 papers identified through the search strategy, 12 qualitative studies met the review inclusion criteria...
August 2, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/28764283/fabrication-and-appraisal-of-poly-lactic-co-glycolic-acid-moxifloxacin-nanoparticles-using-vitamin-e-tpgs-a-potential-intracanal-drug-delivery-agent
#7
Hardik Makkar, Gaurav Patri
INTRODUCTION: Nanotechnology is gaining momentum in the search for ideal biomaterials by dental researchers. The expansible nature of Endodontology deems exploration, learning and scrutinizing newer avenues which have the potential to be applied and investigated. The popularity of polymers as drug delivery vehicles has opened avenues for their application in the root canal system. This study utilized application of biodegradable polymers as potential drug delivery vehicles against Enterococcus faecalis, one of the main reasons for post treatment disease...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763066/-the-quality-of-a-scientific-publication-is-the-product-of-a-sum-of-efforts-and-attributes
#8
Francisco Espinosa-Larrañaga
Todo editor de una publicación médica científica busca que la revista que edita tenga o se reconozca con calidad. La calidad se logra mediante la participación de un conjunto de profesionales (editores, autores, revisores, impresores, diseñadores e incluso lectores) y los resultados de su participación profesional agregan, durante el proceso, propiedades con la finalidad de que el producto, una publicación médica científica, sea valorada por su calidad.
May 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28761249/retrievability-of-calcium-hydroxide-intracanal-medicament-with-three-calcium-chelators-ethylenediaminetetraacetic-acid-citric-acid-and-chitosan-from-root-canals-an-in-vitro-cone-beam-computed-tomography-volumetric-analysis
#9
Ramya Raghu, Geethu Pradeep, Ashish Shetty, P M Gautham, P G Puneetha, T V Satyanarayana Reddy
AIM: This study compared the amount of aqueous-based and oil-based calcium hydroxide remaining in the canal, after removal with two different chelators 17% EDTA, 20% Citric acid and 0.2% Chitosan in combination with ultrasonic agitation. METHODS AND MATERIAL: Cleaning and shaping of root canals of 28 mandibular premolar was done and canals were filled either with Metapex or Ca(OH)2 mixed with distilled water. Volumetric analysis was performed utilizing cone beam-computed tomography (CBCT) after seven days of incubation...
January 2017: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/28761245/comparison-of-efficiency-of-ethylenediaminetetraacetic-acid-citric-acid-and-etidronate-in-the-removal-of-calcium-hydroxide-intracanal-medicament-using-scanning-electron-microscopic-analysis-an-in-vitro-study
#10
Sherin Jose Chockattu, B S Deepak, K Mallikarjun Goud
CONTEXT: Being integral to root canal therapy, obturation can be performed adequately only after the removal of intracanal medicament. One technique involves the use of chelating agents such as ethylenediaminetetraacetic acid (EDTA) and citric acid. Etidronic acid, a relatively new chelator, has smear layer removal ability and lesser dentinal erosion. It is untested in calcium hydroxide (Ca[OH]2) medicament removal. AIM: The aim of this study was to compare the efficiency of irrigation protocols (EDTA, citric acid, and etidronate) in Ca(OH)2 removal...
January 2017: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/28759184/is-non-pharmacological-treatment-an-effective-option-for-chronic-low-back-pain
#11
Alena Ondrejkovicova, Gabriel Petrovics, Katarína Svitkova, Vladimír Balogh
OBJECTIVE: Despite of pain being important warning signal for body ability to respond to internal or external threats, chronic pain is perceived as a discomfort by patients, leading to somatic, emotional and social negative changes. Lifestyle, wrong seating habits and some occupations may contribute to chronic back pain. Therapy for chronic back pain should include not only pharmacological or invasive interventions, but mostly change of lifestyle, physiotherapy and non-pharmacological methods...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28757496/pharmacy-testing-and-the-language-of-truth-in-renaissance-italy
#12
Valentina Pugliano
This article examines the role of testing and innovation in sixteenthcentury Italian pharmacy. I argue that apothecaries were less concerned with testing drugs for efficacy or creating novel products than with reactivating an older Mediterranean pharmacological tradition and studying the materials on which it relied. Their practice was not driven by radical experimentation but by a "culture of tweaking"-of minute operational changes to existing recipes and accommodation of their textual variants-which was rooted in the guild economy fostering incremental over radical innovation and in a humanist reevaluation of past autorities...
2017: Bulletin of the History of Medicine
https://www.readbyqxmd.com/read/28756272/novel-nanosystems-for-the-treatment-of-ocular-inflammation-current-paradigms-and-future-research-directions
#13
REVIEW
Lida Lalu, Vishakha Tambe, Deepak Pradhan, Kritika Nayak, Suchandra Bagchi, Rahul Maheshwari, Kiran Kalia, Rakesh Kumar Tekade
Ocular discomforts involve anterior/posterior-segment diseases, symptomatic distress and associated inflammations and severe retinal disorders. Conventionally, the formulations such as eye drops, eye solutions, eye ointments and lotions, etc. were used as modalities to attain relief from such ocular discomforts. However, eye allows limited access to these traditional formulations due to its unique anatomical structure and dynamic ocular environment and therefore calls for improvement in disease intervention...
July 26, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28755077/processing-of-calamine-with-modern-analytical-techniques-processed-with-huanglian-decoction-and-sanhuang-decoction
#14
Xiang-Long Meng, Jun-Nan Ma, Xiao-Hui Guo, Bing-Chen Liu, Nan-Nan Cui, Kun Li, Shuo-Sheng Zhang
OBJECTIVE: To determine the pyrolysis characteristics of calcined and processed calamine, qualitatively and quantitatively compare the contents of related elements, morphology and functional groups of the pyrolysis products dried at different heating temperatures and explore the critical temperature and the optimal drying temperature for the process of calamine with Huanglian Decoction (HLD, ) and San Huang Decoction (SHD, ). METHODS: Pyrolysis products were prepared by programmable and constantly heating the calcined and processed calamine to or at different heating temperatures...
July 28, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28748761/tyrosinase-electrochemical-biosensors-monitoring-medicinally-significant-substances
#15
Milan Sýs, Karel Vytřas
Nowadays in biosensing, development of analytical techniques is focused on improvement for monitoring biologically active species in living organisms, especially in real time analysis. This article provides an overview of applications of electrochemical tyrosinase biosensors in analysis of medicinally significant substances, otherwise also known as biomarkers. At the beginning, special attention is paid to characterisation of the tyrosinase enzyme, explanation of reaction mechanisms of tyrosinase with various types of electrochemical transducers and techniques needed for stable immobilization of this biocatalyst on the transducer surface used...
July 27, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28748050/assessment-of-facultative-anaerobes-from-the-root-canals-of-deciduous-molars-an-in-vivo-study
#16
Manisha Chandwani, Shweta Chandak
Background. The current research aimed to assess the prevalence of facultative anaerobes isolated from the root canals of deciduous molars. Methods. The present research enrolled 60 children in the 6‒9-year age group based on clinical and radiographic findings. Under aseptic conditions, access cavities were prepared followed by collection of samples from infected root canals with the help of sterile paper points. The samples thus obtained were subjected for microbial assay. Results. It was found that Enterococcus faecalis was isolated in 30% of cases, Escherichia coli in 28...
2017: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/28746531/effective-tobacco-control-measures-agreement-among-medical-students
#17
Stella Regina Martins, Renato Batista Paceli, Marco Antônio Bussacos, Frederico Leon Arrabal Fernandes, Gustavo Faibischew Prado, Elisa Maria Siqueira Lombardi, Mário Terra-Filho, Ubiratan Paula Santos
Objective: To determine the level of agreement with effective tobacco control measures recommended by the World Health Organization and to assess the attitudes toward, knowledge of, and beliefs regarding smoking among third-year medical students at University of São Paulo School of Medicine, located in the city of São Paulo, Brazil. Methods: Between 2008 and 2012, all third-year medical students were invited to complete a self-administered questionnaire based on the Global Health Professionals Student Survey and its additional modules...
May 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28745214/nailfold-capillaroscopy-of-fingers-and-toes-variations-of-normal
#18
Sevdalina Lambova, Ulf Müller-Ladner
INTRODUCTION: Nailfold capillaroscopy is the only method for morphological assessment of nutritive capillaries. The literature data about capillaroscopic findings of toes in healthy individuals are scarce. THE AIM OF THE STUDY: To evaluate and compare the capillaroscopic findings of fingers and toes in healthy subjects. MATERIALS AND METHODS: 22 healthy individuals were included in the study. Capillaroscopic examination was performed with videocapillaroscope Videocap 3...
July 26, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28744732/medicago-truncatula-oleanolic-derived-saponins-are-correlated-with-caterpillar-deterrence
#19
Fanping Cai, Bonnie S Watson, David Meek, David V Huhman, Daniel J Wherritt, Cecile Ben, Laurent Gentzbittel, Brian T Driscoll, Lloyd W Sumner, Jacqueline C Bede
Plant resistance mechanisms to insect herbivory can potentially be bred into crops as an important strategy for integrated pest management. Medicago truncatula ecotypes inoculated with the rhizobium Ensifer medicae (Sinorhizobium medica) WSM419 were screened for resistance to herbivory by caterpillars of the beet armyworm, Spodoptera exigua, through leaf and whole plant choice studies; TN1.11 and F83005.5 are identified as the least and most deterrent ecotypes, respectively. In response to caterpillar herbivory, both ecotypes mount a robust burst of plant defensive jasmonate phytohormones...
July 25, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/28730179/causal-neuro-immune-relationships-at-patients-with-chronic-pyelonephritis-and-cholecystitis-correlations-between-parameters-eeg-hrv-and-white-blood-cell-count
#20
Andriy B Kul'chyns'kyi, Valeriy M Kyjenko, Walery Zukow, Igor L Popovych
We aim to analyze in bounds KJ Tracey's immunological homunculus conception the relationships between parameters of electroencephalogram (EEG) and heart rate variability (HRV), on the one hand, and the parameters of bhite blood cell count, on the other hand. METHODS: In basal conditions in 23 men, patients with chronic pyelonephritis and cholecystitis in remission, recorded EEG ("NeuroCom Standard", KhAI Medica, Ukraine) and HRV ("Cardiolab+VSR", KhAI Medica, Ukraine). In portion of blood counted up white blood cell count...
2017: Open Medicine (Warsaw, Poland)
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