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Transcranial direct current stimulation

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https://www.readbyqxmd.com/read/28231681/noninvasive-transcranial-direct-current-stimulation-tdcs-for-the-treatment-of-orofacial-pain
#1
(no author information available yet)
OBJECTIVE: tDCS is a promising method for the treatment of chronic pain. Electrode placement locations must be chosen in accordance with the density and the time course of the current in order to prevent pathological changes in the underlying tissue. In order to reduce current spatial variability, more electrodes of the same polarity are placed in a circle around the second electrode of the opposite polarity. The applied current produced the greatest changes directly beneath the electrodes: the cathode reduces the excitability of cortical neurons, while the anode has the opposite effect...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231477/effects-of-tdcs-on-motor-learning-and-memory-formation-a-consensus-and-critical-position-paper
#2
REVIEW
Ethan R Buch, Emiliano Santarnecchi, Andrea Antal, Jan Born, Pablo A Celnik, Joseph Classen, Christian Gerloff, Mark Hallett, Friedhelm C Hummel, Michael A Nitsche, Alvaro Pascual-Leone, Walter J Paulus, Janine Reis, Edwin M Robertson, John C Rothwell, Marco Sandrini, Heidi M Schambra, Eric M Wassermann, Ulf Ziemann, Leonardo G Cohen
Motor skills are required for activities of daily living. Transcranial direct current stimulation (tDCS) applied in association with motor skill learning has been investigated as a tool for enhancing training effects in health and disease. Here, we review the published literature investigating whether tDCS can facilitate the acquisition, retention or adaptation of motor skills. Work in multiple laboratories is underway to develop a mechanistic understanding of tDCS effects on different forms of learning and to optimize stimulation protocols...
January 29, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28229937/1-high-definition-transcranial-direct-current-stimulation-to-both-primary-motor-cortices-improves-unimanual-and-bimanual-dexterity
#3
Nils H Pixa, Fabian Steinberg, Michael Doppelmayr
While most research on brain stimulation with transcranial direct current stimulation (tDCS) targets unimanual motor tasks, little is known about its effects on bimanual motor performance. This study aims to investigate the effects of tDCS on unimanual as well as bimanual motor dexterity. We examined the effects of bihemispheric anodal high-definition tDCS (HD-atDCS) on both primary motor cortices (M1) applied concurrent with unimanual and bimanual motor training. We then measured the effects with the Purdue Pegboard Test (PPT) and compared them to a sham stimulation...
February 13, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28229395/transcranial-magnetic-and-direct-current-stimulation-in-children
#4
REVIEW
Mustafa Q Hameed, Sameer C Dhamne, Roman Gersner, Harper L Kaye, Lindsay M Oberman, Alvaro Pascual-Leone, Alexander Rotenberg
Promising results in adult neurologic and psychiatric disorders are driving active research into transcranial brain stimulation techniques, particularly transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), in childhood and adolescent syndromes. TMS has realistic utility as an experimental tool tested in a range of pediatric neuropathologies such as perinatal stroke, depression, Tourette syndrome, and autism spectrum disorder (ASD). tDCS has also been tested as a treatment for a number of pediatric neurologic conditions, including ASD, attention-deficit/hyperactivity disorder, epilepsy, and cerebral palsy...
February 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28227989/computational-models-of-non-invasive-brain-and-spinal-cord-stimulation
#5
Pedro C Miranda, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes, Pedro C Miranda, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes, Sofia R Fernandes, Pedro C Miranda, Cornelia Wenger, Ricardo Salvador
Non-invasive brain and spinal cord stimulation techniques are increasingly used for diagnostic and therapeutic purposes. Knowledge of the spatial distribution of the induced electric field is necessary to interpret experimental results and to optimize field delivery. Since the induced electric field cannot be measured in vivo in humans, computational models play a fundamental role in determining the characteristics of the electric field. We produced computational models of the head and trunk to calculate the electric field induced in the brain and spinal cord by transcranial magnetic stimulation, transcranial direct current stimulation and transcutaneous spinal cord direct current stimulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227698/predicting-brain-stimulation-treatment-outcomes-of-depressed-patients-through-the-classification-of-eeg-oscillations
#6
Alaa M Al-Kaysi, Ahmed Al-Ani, Colleen K Loo, Michael Breakspear, Tjeerd W Boonstra, Alaa M Al-Kaysi, Ahmed Al-Ani, Colleen K Loo, Michael Breakspear, Tjeerd W Boonstra, Michael Breakspear, Ahmed Al-Ani, Tjeerd W Boonstra, Colleen K Loo
Major depressive disorder (MDD) is a mental disorder that is characterized by negative thoughts, mood and behavior. Transcranial direct current stimulation (tDCS) has recently emerged as a promising brain-stimulation treatment for MDD. A standard tDCS treatment involves numerous sessions that run over a few weeks, however, not all participants respond to this type of treatment. This study aims to predict which patients improve in mood and cognition in response to tDCS treatment by analyzing electroencephalography (EEG) of MDD patients that was collected at the start of tDCS treatment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227696/oscillatory-brain-activity-changes-by-anodal-tdcs-an-ecog-study-on-anesthetized-beagles
#7
Sehyeon Jang, Donghyeon Kim, Junkil Been, Hohyun Cho, Sung Chan Jun, Sehyeon Jang, Donghyeon Kim, Junkil Been, Hohyun Cho, Sung Chan Jun, Donghyeon Kim, Junkil Been, Sung Chan Jun, Hohyun Cho, Sehyeon Jang
Measuring neuronal activity of transcranial direct current stimulation (tDCS) is essential for investigating tDCS in stimuli or after stimuli effects. The aim of this study was to investigate the oscillatory changes from anodal tDCS using electrocorticography (ECoG) on beagles. We applied 2 mA anodal tDCS and monitored the ECoG signals (32 channels, 512 Hz sampling rate) for 15 minutes in three anesthetized beagles. Then, we compared the power changes before, during, and after tDCS in six different bands (delta, theta, alpha, beta, low-gamma, and mid-gamma bands)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227693/using-bioimpedance-spectroscopy-parameters-as-real-time-feedback-during-tdcs
#8
Isar Nejadgholi, Herschel Caytak, Miodrag Bolic, Isar Nejadgholi, Herschel Caytak, Miodrag Bolic, Isar Nejadgholi, Miodrag Bolic, Herschel Caytak
An exploratory analysis is carried out to investigate the feasibility of using BioImpedance Spectroscopy (BIS) parameters, measured on scalp, as real-time feedback during Transcranial Direct Current Stimulation (tDCS). TDCS is shown to be a potential treatment for neurological disorders. However, this technique is not considered as a reliable clinical treatment, due to the lack of a measurable indicator of treatment efficacy. Although the voltage that is applied on the head is very simple to measure during a tDCS session, changes of voltage are difficult to interpret in terms of variables that affect clinical outcome...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227541/effects-of-electrode-displacement-in-high-definition-transcranial-direct-current-stimulation-a-computational-study
#9
Hyeon Seo, Donghyeon Kim, Sung Chan Jun, Hyeon Seo, Donghyeon Kim, Sung Chan Jun, Donghyeon Kim, Sung Chan Jun, Hyeon Seo
In order to understand better the ways in which cortical excitability is linked to target brain areas, this study describes the effects of focalized high-definition transcranial direct current stimulation (HD-tDCS), and investigates the way in which these effects persisted after the stimulus electrodes were displaced from the target area. We constructed a 3D volume conduction model of an anatomically realistic head that is ideal for HD-tDCS, as well as compartmental models of layer 3 and layer 5 pyramidal neurons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227409/projected-current-density-comparison-in-tdcs-block-and-smooth-fe-modeling
#10
Aprinda Indahlastari, Munish Chauhan, Rosalind J Sadleir, Aprinda Indahlastari, Munish Chauhan, Rosalind J Sadleir, Aprinda Indahlastari, Munish Chauhan, Rosalind J Sadleir
Current density distribution and projected current density calculation following transcranial direct current stimulation (tDCS) forward model in a human head were compared between two modeling pipelines: block and smooth. Block model was directly constructed from MRI voxel resolution and simulated in C. Smooth models underwent a boundary smoothing process by applying recursive Gaussian filters and simulated in COMSOL. Three smoothing levels were added to determine their effects on current density distribution compared to block models...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227393/an-integrated-neuroprotective-intervention-for-brain-ischemia-validated-by-ecog-fpam
#11
Yu-Hang Liu, Lun-De Liao, Su Jing Chan, Aishwarya Bandla, Nitish V Thakor, Yu-Hang Liu, Lun-De Liao, Su Jing Chan, Aishwarya Bandla, Nitish V Thakor, Yu-Hang Liu, Aishwarya Bandla, Nitish V Thakor, Su Jing Chan, Lun De Liao
Brain ischemia is a neurological deficit caused by a reduction in the blood supply to tissue, and one of the leading causes of disability in the world. Currently, the most well-known therapeutic agent for ischemia recovery is recombinant tissue plasminogen activator (rtPA), but it is viable for only a small portion (approximately 3.6%) of ischemic patients and may cause side effects such as tissue damage. Thus, introducing a new therapeutic concept for ischemia, we proposed an integrated intervention combining global and focal stimulations in this article...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226859/effects-of-prefrontal-anodal-transcranial-direct-current-stimulation-on-working-memory-and-reaction-time
#12
Ines S Verissimo, Isabel M Barradas, Tiago T Santos, Pedro C Miranda, Hugo A Ferreira, Ines S Verissimo, Isabel M Barradas, Tiago T Santos, Pedro C Miranda, Hugo A Ferreira, Pedro C Miranda, Ines S Verissimo, Tiago T Santos, Isabel M Barradas, Hugo A Ferreira
Transcranial direct current stimulation (tDCS) has proven to be a useful tool in the scientific research community, particularly for clinical investigation purposes. Neuroimaging studies indicate that there is a connection between the prefrontal cortex (PFC) and working memory (WM), as well as between the primary motor cortex and reaction time (RT). Thus, our goal was to evaluate the effect of anodal stimulation of the PFC, with respect to WM and RT. We tested 20 healthy subjects randomized into two groups - half received active stimulation and the other half sham stimulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226856/evaluation-of-the-electric-field-in-the-brain-during-transcranial-direct-current-stimulation-a-sensitivity-analysis
#13
Laura Santos, Miguel Martinho, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes, Oscar Ripolles, Giulio Ruffini, Pedro C Miranda, Laura Santos, Miguel Martinho, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes, Oscar Ripolles, Giulio Ruffini, Pedro C Miranda, Laura Santos, Miguel Martinho, Cornelia Wenger, Ricardo Salvador, Oscar Ripolles, Giulio Ruffini, Sofia R Fernandes, Pedro C Miranda
The use of computational modeling studies accounts currently for the best approach to predict the electric field (E-field) distribution in transcranial direct current stimulation. As with any model, the values attributed to the physical properties, namely the electrical conductivity of the tissues, affect the predicted E-field distribution. A wide range of values for the conductivity of most tissues is reported in the literature. In this work, we used the finite element method to compute the E-field induced in a realistic human head model for two electrode montages targeting the left dorso-lateral prefrontal cortex (DLPFC)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226855/on-comparing-in-vivo-intracranial-recordings-in-non-human-primates-to-predictions-of-optimized-transcranial-electrical-stimulation
#14
Abhishek Datta, Matthew R Krause, Praveen K Pilly, Jaehoon Choe, Theodoras P Zanos, Chris Thomas, Christopher C Pack, Abhishek Datta, Matthew R Krause, Praveen K Pilly, Jaehoon Choe, Theodoras P Zanos, Chris Thomas, Christopher C Pack, Jaehoon Choe, Chris Thomas, Theodoros P Zanos, Abhishek Datta, Praveen K Pilly, Christopher C Pack, Matthew R Krause
Transcranial electrical stimulation (tES) can be optimized to achieve maximal current flow at desired brain regions. The aim of this study was to characterize electric field magnitudes generated by tES optimization and to compare them to experimentally induced values as determined by data from intracranial electrodes. Local field potentials were recorded from two monkeys with implanted multi-site intracranial Utah arrays during transcranial direct current stimulation (tDCS), and the neural effect predictions obtained from optimized electrode placement were assessed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225813/the-effects-of-cervical-transcutaneous-spinal-direct-current-stimulation-on-motor-pathways-supplying-the-upper-limb-in-humans
#15
Siobhan C Dongés, Jessica M D'Amico, Jane E Butler, Janet L Taylor
Non-invasive, weak direct current stimulation can induce changes in excitability of underlying neural tissue. Many studies have used transcranial direct current stimulation to induce changes in the brain, however more recently a number of studies have used transcutaneous spinal direct current stimulation to induce changes in the spinal cord. This study further characterises the effects following cervical transcutaneous spinal direct current stimulation on motor pathways supplying the upper limb. In Study 1, on two separate days, participants (n = 12, 5 F) received 20 minutes of either real or sham direct current stimulation at 3 mA through electrodes placed in an anterior-posterior configuration over the neck (anode anterior)...
2017: PloS One
https://www.readbyqxmd.com/read/28225155/remotely-supervised-transcranial-direct-current-stimulation-increases-the-benefit-of-at-home-cognitive-training-in-multiple-sclerosis
#16
Leigh Charvet, Michael Shaw, Bryan Dobbs, Ariana Frontario, Kathleen Sherman, Marom Bikson, Abhishek Datta, Lauren Krupp, Esmail Zeinapour, Margaret Kasschau
OBJECTIVE: To explore the efficacy of remotely-supervised transcranial direct current stimulation (RS-tDCS) paired with cognitive training (CT) exercise in participants with multiple sclerosis (MS). METHODS: In a feasibility study of RS-tDCS in MS, participants completed ten sessions of tDCS paired with CT (1.5 mA × 20 min, dorsolateral prefrontal cortex montage). RS-tDCS participants were compared to a control group of adults with MS who underwent ten 20-min CT sessions through the same remotely supervised procedures...
February 22, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28222543/anodal-cerebellar-tdcs-modulates-lower-extremity-pain-perception
#17
Manuel Pereira, Basil Rafiq, Einul Chowdhury, Jacqueline Babayev, HyunJi Boo, Rowan Metwaly, Sandilya Priam, Eileen Chusid, Fortunato Battaglia
BACKGROUND: Previous studies have investigated the use of transcranial direct current stimulation (tDCS) for pain management. The studies investigating therapeutic neuromodulation with tDCS for lower extremity pain are scarce and inconclusive. OBJECTIVE: The aim of the present study was to analyze the effects of cerebellar tDCS on lower extremity sensory and pain thresholds in healthy volunteers. METHODS: This was a single-blind crossover repeated-measure study...
January 31, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28220641/safety-review-of-transcranial-direct-current-stimulation-in-stroke
#18
REVIEW
Cristina Russo, Maíra I Souza Carneiro, Nadia Bolognini, Felipe Fregni
OBJECTIVES: The safety, painless, and tolerability features of transcranial Direct Current Stimulation (tDCS) have prompted the research on the therapeutic effects of this technique in stroke; however, an in-depth and unarguable examination of the adverse effects of tDCS in stroke patients is still lacking. This review analyzes the reported adverse effects in stroke, looking for factors that may induce side-effects. MATERIALS AND METHODS: A comprehensive search of articles published from 1998 to 2015 describing tDCS application in stroke patients performed through data extraction from MEDLINE/PubMed database...
February 21, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28217104/priming-neural-circuits-to-modulate-spinal-reflex-excitability
#19
Stephen P Estes, Jennifer A Iddings, Edelle C Field-Fote
While priming is most often thought of as a strategy for modulating neural excitability to facilitate voluntary motor control, priming stimulation can also be utilized to target spinal reflex excitability. In this application, priming can be used to modulate the involuntary motor output that often follows central nervous system injury. Individuals with spinal cord injury (SCI) often experience spasticity, for which antispasmodic medications are the most common treatment. Physical therapeutic/electroceutic interventions offer an alternative treatment for spasticity, without the deleterious side effects that can accompany pharmacological interventions...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28213645/transcranial-direct-current-stimulation-modulates-neuronal-networks-in-attention-deficit-hyperactivity-disorder
#20
Anna Sotnikova, Cornelia Soff, Enzo Tagliazucchi, Katja Becker, Michael Siniatchkin
Anodal transcranial direct current stimulation (tDCS) of the prefrontal cortex has been repeatedly shown to improve working memory (WM). Since patients with attention deficit hyperactivity disorder (ADHD) are characterized by both underactivation of the prefrontal cortex and deficits in WM, the modulation of prefrontal activity with tDCS in ADHD patients may increase their WM performance as well as improve the activation and connectivity of the WM network. In the present study, this hypothesis was tested using a double-blind sham-controlled experimental design...
February 17, 2017: Brain Topography
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