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Ludivine Lebourg, Sonia Amato, Daniel Toledano, Thierry Petitclerc, Caroline Créput
Online hemodiafiltration has been shown to have many benefits in terms of morbi-mortality and to increase middle weight molecules removal. However, this technique is supposed to have an additional cost which may be an obstacle to increase its development in hemodialysis centers. The aim of the study is to achieve an accurate pharmaco-economic evaluation for determining the real overcost of online hemodiafiltration (OL-HDF) in comparison with high flux hemodialysis (HF-HD) using standard priming. We have identified the additional costs related to the consumables and monitors and the additional costs imposed by the technique itself (water consumption and microbiological analysis)...
July 2013: Néphrologie & Thérapeutique
H Boudra, S Saivin, P Delagrange, M F Malmary, P Genissel, G Houin
In this study, an original surgical implantation technique in the confluens sinuum via the superior sagittal vein was developed to quantify melatonin secretion by the pineal gland. Melatonin (CAS 73-31-4) was determined using gas chromatography couples to negative ion chemical ionisation mass spectrometry following liquid extraction and derivatisation by penta-fluoropropionic acid anhydride (PFPA). The minimum detectable amount was 40 fg per injection, corresponding to 1 in dialysate. The assay was linear in the range 20-1000 pg...
October 1999: Arzneimittel-Forschung
J P Sichel, A Baldauf, M Horber, P Wasser, J F Marichal, B Faller
The authors report their experience in using Continuous Ambulatory Peritoneal Dialysis (C.A.P.D.), in the treatment of chronic schizophrenia. This attempt refers to studies which confirm any role of endorphins in the origin of schizophrenia. Consecutively to american authors who found endorphins (molecular weight 3 300) in the dialysat of hemodialysed schizophrenics, they choose C.A.P.D. This continue technic of dialysis is more efficient than hemodialysis in removal of substances which molecular weight is between 1 500 and 5 000...
1981: L'Encéphale
B Faller
In contrast with hemodialysis (HD) Continuous Ambulatory Peritoneal Dialysis (CAPD) is a permanent dialysis procedure proposed to the chronic renal patients. Through a permanent peritenoal catheter the patients exchange 2 litres of dialysate 4 times a day, 7 days a week, as soon as the dialysat/plasma concentration for urea reaches 1. Inflow and outflow of the fluid is obtained by gravity, without machine. The short term survival rate is comparable between HD and CAPD. After 5 years, some patients, loosing the residual renal function, need to increase the possibilities of CAPD...
April 21, 1991: La Revue du Praticien
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