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https://www.readbyqxmd.com/read/28231244/unexpectedly-high-leprosy-seroprevalence-detected-using-a-random-surveillance-strategy-in-midwestern-brazil-a-comparison-of-elisa-and-a-rapid-diagnostic-test
#1
Marco Andrey C Frade, Natália A de Paula, Ciro M Gomes, Sebastian Vernal, Fred Bernardes Filho, Helena B Lugão, Marilda M M de Abreu, Patrícia Botini, Malcolm S Duthie, John S Spencer, Rosa Castália F R Soares, Norma T Foss
BACKGROUND: Leprosy diagnosis is mainly based on clinical evaluation, although this approach is difficult, especially for untrained physicians. We conducted a temporary campaign to detect previously unknown leprosy cases in midwestern Brazil and to compare the performance of different serological tests. METHODS: A mobile clinic was stationed at the main bus terminal in Brasília, Brazil. Volunteers were quizzed and given a clinical exam to allow categorization as either patients, known contacts of patients or non-contacts, and blood was collected to determine anti-PGL-I and anti-LID-1 antibody titers by ELISA and by the NDO-LID rapid test...
February 23, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28227634/design-and-validation-of-a-wearable-drl-less-eeg-using-a-novel-fully-reconfigurable-architecture
#2
Ruhi Mahajan, Bashir I Morshed, Gavin M Bidelman, Ruhi Mahajan, Bashir I Morshed, Gavin M Bidelman, Bashir I Morshed, Ruhi Mahajan, Gavin M Bidelman
The conventional EEG system consists of a driven-right-leg (DRL) circuit, which prohibits modularization of the system. We propose a Lego-like connectable fully reconfigurable architecture of wearable EEG that can be easily customized and deployed at naturalistic settings for collecting neurological data. We have designed a novel Analog Front End (AFE) that eliminates the need for DRL while maintaining a comparable signal quality of EEG. We have prototyped this AFE for a single channel EEG, referred to as Smart Sensing Node (SSN), that senses brain signals and sends it to a Command Control Node (CCN) via an I(2)C bus...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226854/a-distributed-current-stimulator-asic-for-high-density-neural-stimulation
#3
Jeong Hoan Park, Chaebin Kim, Seung-Hee Ahn, Tae Mok Gwon, Joonsoo Jeong, Sang Beom Jun, Sung June Kim, Jeong Hoan Park, Chaebin Kim, Seung-Hee Ahn, Tae Mok Gwon, Joonsoo Jeong, Sang Beom Jun, Sung June Kim, Sung June Kim, Joonsoo Jeong, Sang Beom Jun, Tae Mok Gwon, Chaebin Kim, Seung-Hee Ahn, Jeong Hoan Park
This paper presents a novel distributed neural stimulator scheme. Instead of a single stimulator ASIC in the package, multiple ASICs are embedded at each electrode site for stimulation with a high density electrode array. This distributed architecture enables the simplification of wiring between electrodes and stimulator ASIC that otherwise could become too complex as the number of electrode increases. The individual ASIC chip is designed to have a shared data bus that independently controls multiple stimulating channels...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226253/modeling-single-vehicle-run-off-road-crash-severity-in-rural-areas-accounting-for-unobserved-heterogeneity-and-age-difference
#4
Linfeng Gong, Wei David Fan
This study investigates factors that significantly contribute to the severity of driver injuries resulting from single-vehicle run-off-road (SV ROR) crashes. A mixed logit model approach is employed to explore the potential unobserved heterogeneous effects associated with each age group: young (ages 16-24), middle-aged (ages 25-65), and older drivers (ages over 65). Likelihood ratio tests indicated that the development of separate injury severity models for each age group is statistically superior to estimating a single model using all data...
February 19, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28220022/using-metaphors-to-explain-molecular-testing-to-cancer-patients
#5
Ana P M Pinheiro, Rachel H Pocock, Margie D Dixon, Walid L Shaib, Suresh S Ramalingam, Rebecca D Pentz
BACKGROUND: Molecular testing to identify targetable molecular alterations is routine practice for several types of cancer. Explaining the underlying molecular concepts can be difficult, and metaphors historically have been used in medicine to provide a common language between physicians and patients. Although previous studies have highlighted the use and effectiveness of metaphors to help explain germline genetic concepts to the general public, this study is the first to describe the use of metaphors to explain molecular testing to cancer patients in the clinical setting...
February 20, 2017: Oncologist
https://www.readbyqxmd.com/read/28216996/busman-s-stomach-and-the-embodiment-of-modernity
#6
Rhodri Hayward
This paper examines the relationship between the gastric illness, 'busman's stomach' and the Coronation bus strike of May 1937 in which 27,000 London busworkers walked out for better working conditions and a seven-and-half-hour day. It explores the way in which new patterns of somatisation, gastroenterological techniques, psychological theories and competing understandings of time worked together to create new political institutions and new forms of political action in inter-war Britain.
January 2, 2017: Contemporary British History
https://www.readbyqxmd.com/read/28212510/impact-of-paint-shop-decanter-effluents-on-biological-treatability-of-automotive-industry-wastewater
#7
Didem Güven, Oytun Hanhan, Elif Ceren Aksoy, Güçlü Insel, Emine Çokgör
A lab-scale Sequencing Batch Reactor (SBR) was implemented to investigate biological treatability and kinetic characteristics of paint shop wastewater (PSW) together with main stream wastewater (MSW) of a bus production factory. Readily biodegradable and slowly biodegradable COD fractions of MWS were determined by respirometric analysis: 4.2% (SS), 10.4% (SH) and 59.3% (XS). Carbon and nitrogen removal performance of the SBR feeding with MSW alone were obtained as 89% and 58%, respectively. When PSW was introduced to MSW, both carbon and nitrogen removal were deteriorated...
January 29, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28208621/a-framework-for-bus-trajectory-extraction-and-missing-data-recovery-for-data-sampled-from-the-internet
#8
Changfei Tong, Huiling Chen, Qi Xuan, Xuhua Yang
This paper presents a novel framework for trajectories' extraction and missing data recovery for bus traveling data sampled from the Internet. The trajectory extraction procedure is composed of three main parts: trajectory clustering, trajectory cleaning and trajectory connecting. In the clustering procedure, we focus on feature construction and parameter selection for the fuzzy C-means clustering method. Following the clustering procedure, the trajectory cleaning algorithm is implemented based on a new introduced fuzzy connecting matrix, which evaluates the possibility of data belonging to the same trajectory and helps detect the anomalies in a ranked context-related order...
February 10, 2017: Sensors
https://www.readbyqxmd.com/read/28208017/tailoring-cellular-uptake-and-fluorescence-of-poly-2-oxazoline-based-nanogels
#9
Ulrich S Schubert, Matthias Hartlieb, Tanja Bus, Joachim Kübel, David Pretzel, Stephanie Hoeppener, Meike N Leiske, Kristian Kempe, Benjamin Dietzek
Controlling the size and charge of nanometer sized objects is of upmost importance for their interactions with cells. We herein present the synthesis of poly(2-oxazoline) based nanogels comprising a hydrophilic shell and an amine containing core compartment. Amine groups were cross-linked using glutaraldehyde resulting in imine based nanogels. As a drug model, amino fluorescein was covalently immobilized within the core, quenching excessive aldehyde functions. By varying the amount of cross-linker, the zeta potential and, hence, the cellular uptake could be adjusted...
February 16, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28194081/excessive-sleepiness-sleep-hygiene-and-coping-strategies-among-night-bus-drivers-a-cross-sectional-study
#10
Uma Maheswari Krishnaswamy, Mamta S Chhabria, Aditi Rao
BACKGROUND: Sleep disruption and excessive sleepiness are the known consequences of shift work. The recent spate of night-time road and air accidents, with some being directly attributed to driver sleepiness prompted us to undertake this study. AIMS: To screen for excessive sleepiness, coping practices, and post-shift sleep hygiene in night bus drivers. SETTINGS AND DESIGN: This prospective study was carried out on night bus drivers of a public transport organization in Bengaluru, Karnataka, India...
May 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28188054/exposure-to-air-pollutants-during-commuting-in-london-are-there-inequalities-among-different-socio-economic-groups
#11
Ioar Rivas, Prashant Kumar, Alex Hagen-Zanker
People with low income often experience higher exposures to air pollutants. We compared the exposure to particulate matter (PM1, PM2.5 and PM10), Black Carbon (BC) and ultrafine particles (PNCs; 0.02-1μm) for typical commutes by car, bus and underground from 4 London areas with different levels of income deprivation (G1 to G4, from most to least deprived). The highest BC and PM concentrations were found in G1 while the highest PNC in G3. Lowest concentrations for all pollutants were observed in G2. We found no systematic relationship between income deprivation and pollutant concentrations, suggesting that differences between transport modes are a stronger influence...
February 7, 2017: Environment International
https://www.readbyqxmd.com/read/28176494/ultrasound-bladder-wall-thickness-and-detrusor-overactivity-a-multicentre-test-accuracy-study
#12
P Latthe, L Middleton, S Rachaneni, S McCooty, J Daniels, A Coomarasamy, M Balogun, J Duckett, R Thakar, I Goranitis, T Roberts, J Deeks
OBJECTIVE: Women with overactive bladder (OAB) often undergo urodynamics before invasive treatments are considered. Ultrasound measurement of bladder wall thickness (BWT) is a less invasive, less expensive and widely available test. It has the potential to diagnose the presence of detrusor overactivity (DO). We aimed to evaluate the accuracy of BWT in the diagnosis of DO. DESIGN: Prospective cohort study. SETTING: Twenty-two UK clinics (university and district general hospitals)...
February 7, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28152934/an-approach-to-implementing-meaningful-change-in-a-provincial-health-care-system
#13
Elizabeth Lockhart, Michael Donald Brundage, Margaret Hart, Mark Hartman, Sophie Foxcroft, Lindsay Elizabeth Reddeman, Carina Simniceanu, Marissa Mendelsohn, Lisa Favell, Jonathan Wang, Elaine Meertens, Eric Gutierrez, Padraig Richard Warde
: 120 Background: Radiation treatment (RT) is essential to cancer management, contributing to cure and symptom control. With increasing cancer incidence and treatment complexity, health systems must adapt to ensure patients (pts) receive the highest quality of care. METHODS: With the objective of ensuring equitable access to high-quality, safe care, Cancer Care Ontario (CCO), a provincial government agency, identified provincial variability in RT activities. As a result, CCO prioritized 3 quality initiatives over the past 7 years: 1) Access to Intensity Modulated RT (IMRT) (2008-2013); 2) Peer Review of RT plans due to increasing RT planning complexity and the existence of high-profile RT errors (2012-present); and 3) Ensuring equitable access to RT (RT Utilization) (2014-present)...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28151487/saturday-driving-restrictions-fail-to-improve-air-quality-in-mexico-city
#14
Lucas W Davis
Policymakers around the world are turning to license-plate based driving restrictions in an effort to address urban air pollution. The format differs across cities, but most programs restrict driving once or twice a week during weekdays. This paper focuses on Mexico City, home to one of the oldest and best-known driving restriction policies. For almost two decades Mexico City's driving restrictions applied during weekdays only. This changed recently, however, when the program was expanded to include Saturdays...
February 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28146034/interprofessional-mass-casualty-incident-simulation-design-protocol-to-prepare-prelicensure-nursing-students-to-respond-to-a-disaster
#15
Kelley Strout, Deborah A Saber, Lisa Swanson Caruso, Charlene Ingwell-Spolan, Aiden Koplovsky, Erica M Caron, Jennifer Federico, Colin Hulst, Isabella Etro
Nurses need to be prepared to respond to mass casualty incidents. Simulation is an ideal teaching intervention that can be used to prepare nursing students to effectively triage patients and allocate limited resources. This article describes a detailed interprofessional mass casualty simulation of a bus crash with 32 victims. Nursing students trained with emergency responders with students acting as charge nurses throughout the simulation. The details of the simulation are provided for faculty to replicate.
February 1, 2017: Nurse Educator
https://www.readbyqxmd.com/read/28141727/-media-addiction-in-a-10-year-old-boy
#16
Scott Brown, Michael A Scharf, Cristina Bustos, Denise Chavira, Martin T Stein
Bryan is a 10-year-old boy who is brought to his pediatrician by his parents with concerns about oppositional behaviors. Bryan's parents report that he has always been hyperactive and oppositional since a very young age. He has been previously diagnosed with attention-deficit hyperactivity disorder and has been treated with appropriate stimulant medications for several years; however, despite this, his parents feel increasingly unable to manage his difficult behaviors. He refuses to do chores or follow through with household routines...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28134060/a-novel-assay-for-the-detection-of-anthelmintic-activity-mediated-by-cuticular-damage-to-nematodes-validation-on-caenorhabditis-elegans-exposed-to-cysteine-proteinases
#17
A M Phiri, D I DE Pomerai, D J Buttle, J M Behnke
Plant cysteine proteinases (CPs) from Carica papaya kill parasitic and free-living nematodes in vitro by hydrolysis of the worm cuticle, a mechanism that is different to all commercially available synthetic anthelmintics. We have developed a cheap and effective, rapid-throughput Caenorhabditis elegans-based assay for screening plant CP extracts for anthelmintic activity targeting cuticular integrity. The assay exploits colorimetric methodology for assessment of cuticular damage, and is based on the ability of viable cells to incorporate and bind Neutral red dye within lysosomes and to release the dye when damaged...
January 30, 2017: Parasitology
https://www.readbyqxmd.com/read/28132665/exploring-injury-panorama-consequences-and-recovery-among-bus-crash-survivors-a-mixed-methods-research-study
#18
Isabelle Doohan, Ulf Björnstig, Ulrika Östlund, Britt-Inger Saveman
OBJECTIVE: The aim of this study was to explore physical and mental consequences and injury mechanisms among bus crash survivors to identify aspects that influence recovery. METHODS: The study participants were the total population of survivors (N=56) from a bus crash in Sweden. The study had a mixed-methods design that provided quantitative and qualitative data on injuries, mental well-being, and experiences. Results from descriptive statistics and qualitative thematic analysis were interpreted and integrated in a mixed-methods analysis...
January 30, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28123736/rare-virilizing-granulosa-cell-tumor-in-an-adolescent
#19
Dorottya Bús, Mária Buzogány, Gyöngyi Nagy, György Vajda
Hormone-producing malignancies are rare in children or adolescent patients: Only 0.1% of all ovarian tumors and 4-5% of granulosa cell tumors occur in the sexually non-active ages. Granulosa cell tumors (GCTs) are sex cord-stromal tumors of the ovary, representing 7-8% of all ovarian neoplasms. A total of 95% of all GCTs are adult-type, and only 5% are diagnosed as juvenile-type GCT. A majority of children with juvenile-type GCT present with isosexual precocious pseudopuberty due to excessive estrogen production, although virilizing, testosterone-producing, juvenile-type GCTs are rare, occurring only in 2-3% of cases...
January 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28118764/facilitators-for-traveling-with-local-public-transport-among-people-with-mild-cognitive-limitations-after-stroke
#20
Agneta Ståhl, Eva Månsson Lexell
INTRODUCTION: Previous research of how people with stroke manage public transport has mainly focused on barriers due to physical limitations whereas the influence of cognitive limitations is scarce. There is also a lack of knowledge of facilitators that can help to overcome these barriers. The aim of this study was to describe facilitators for travelling with public transport, e.g. local buses, among people with mild cognitive limitations after stroke. METHODS: A multiple case study research design was used, where quantitative and qualitative data were utilized, and analysed according to a mixed methods design...
January 24, 2017: Scandinavian Journal of Occupational Therapy
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