Hiba J Mustafa, Enaja V Sambatur, Giorgio Pagani, Francesco D'Antonio, Emeline Maisonneuve, Paul Maurice, Carolien Zwiers, E J T Joanne Verweij, Anna Flood, Alireza A Shamshirsaz, Jean-Marie Jouannic, Asma Khalil
OBJECTIVE: To investigate the outcomes associated with the administration of maternal intravenous immunoglobulin (IVIG) in high-risk red blood cell (RBC) alloimmunized pregnancies. DATA SOURCES: We systematically searched Medline, Embase, and Cochrane Library until June 2023. STUDY ELIGIBILITY CRITERIA: We included studies reporting on pregnancies with severe RBC alloimmunization, defined as either a previous fetal or neonatal death or the need for IUT before 24 weeks in the previous pregnancy as a result of hemolytic disease of fetus and newborn (HDFN)...
April 6, 2024: American Journal of Obstetrics and Gynecology