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Stroke prediction atrial fibrillation

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https://www.readbyqxmd.com/read/27903388/-predicting-values-of-chads2-and-cha2-ds2-vasc-scores-on-stroke-in-patients-with-non-atrial-fibrillation-heart-diseases
#1
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No abstract text is available yet for this article.
November 24, 2016: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/27899169/is-it-time-to-incorporate-the-left-atrial-size-to-the-current-stroke-risk-scoring-systems-for-atrial-fibrillation-%C3%A2
#2
Jonathan D Gardner, William Paul Skelton, Rami N Khouzam
Primary care physicians and cardiologists rely on risk scoring systems, which consist of a number of clinical variables used together, to predict stroke risk in patients with atrial fibrillation (AF). Ultimately, this helps in determining the need for anticoagulation. Left atrial size is not used in any stroke risk scoring system to stratify patients at risk for cardioembolic stroke. Throughout the literature, there is much debate surrounding the use of left atrial size as an additional risk factor for stroke in patients with and without AF...
September 2016: Current Problems in Cardiology
https://www.readbyqxmd.com/read/27893055/assessment-of-use-vs-discontinuation-of-oral-anticoagulation-after-pulmonary-vein-isolation-in-patients-with-atrial-fibrillation
#3
Sara Själander, Fredrik Holmqvist, J Gustav Smith, Pyotr G Platonov, Milos Kesek, Peter J Svensson, Carina Blomström-Lundqvist, Fariborz Tabrizi, Jari Tapanainen, Dritan Poci, Anders Jönsson, Anders Själander
Importance: Pulmonary vein isolation (PVI) is a recommended treatment for patients with atrial fibrillation, but it is unclear whether it results in a lower risk of stroke. Objectives: To investigate the proportion of patients discontinuing anticoagulation treatment after PVI in association with the CHA2DS2-VASc (congestive heart failure, hypertension, age ≥75 years [doubled], diabetes, stroke [doubled], vascular disease, age 65-74 years, sex category [female]) score, identify factors predicting stroke after PVI, and explore the risk of cardiovascular events after PVI in patients with and without guideline-recommended anticoagulation treatment...
November 23, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27890386/2016-guidelines-of-the-taiwan-heart-rhythm-society-and-the-taiwan-society-of-cardiology-for-the-management-of-atrial-fibrillation
#4
Chern-En Chiang, Tsu-Juey Wu, Kwo-Chang Ueng, Tze-Fan Chao, Kuan-Cheng Chang, Chun-Chieh Wang, Yenn-Jiang Lin, Wei-Hsian Yin, Jen-Yuan Kuo, Wei-Shiang Lin, Chia-Ti Tsai, Yen-Bin Liu, Kun-Tai Lee, Li-Jen Lin, Lian-Yu Lin, Kang-Ling Wang, Yi-Jen Chen, Mien-Cheng Chen, Chen-Chuan Cheng, Ming-Shien Wen, Wen-Jone Chen, Jyh-Hong Chen, Wen-Ter Lai, Chuen-Wang Chiou, Jiunn-Lee Lin, San-Jou Yeh, Shih-Ann Chen
Atrial fibrillation (AF) is the most common sustained arrhythmia. Both the incidence and prevalence of AF are increasing, and the burden of AF is becoming huge. Many innovative advances have emerged in the past decade for the diagnosis and management of AF, including a new scoring system for the prediction of stroke and bleeding events, the introduction of non-vitamin K antagonist oral anticoagulants and their special benefits in Asians, new rhythm- and rate-control concepts, optimal endpoints of rate control, upstream therapy, life-style modification to prevent AF recurrence, and new ablation techniques...
November 24, 2016: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/27876310/impact-of-atrial-natriuretic-peptide-value-for-predicting-paroxysmal-atrial-fibrillation-in-ischemic-stroke-patients
#5
Hiroshi Shiroto, Hirofumi Tomita, Joji Hagii, Norifumi Metoki, Ayaka Fujita, Takaatsu Kamada, Koki Takahashi, Shin Saito, Satoko Sasaki, Hiroyasu Hitomi, Satoshi Seino, Yoshiko Baba, Takamitsu Uchizawa, Manabu Iwata, Shigeo Matsumoto, Minoru Yasujima, Ken Okumura
INTRODUCTION: The impact of atrial natriuretic peptide (ANP) value for predicting paroxysmal atrial fibrillation (pAF) in ischemic stroke patients remains uncertain. METHODS: The consecutive 222 ischemic stroke patients (median 77 [IQR 68-83] years old, 93 females) within 48 hours after onset were retrospectively studied. Plasma ANP and brain natriuretic peptide (BNP) levels were simultaneously measured at admission. Of all, 158 patients had no evidence of atrial fibrillation (AF) (sinus rhythm [SR] group), 25 patients had pAF (pAF group), and the other 39 patients had chronic AF (cAF group)...
November 18, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27874936/relationship-between-atrial-fibrillation-and-heart-failure
#6
C-Y Hu, C-Y Wang, J-Y Li, J Ma, Z-Q Li
Heart failure (HF) and atrial fibrillation (AF) are major health issues and often co-exist. HF and AF also share common mechanisms, as well as therapies and treatment strategies. The relationship between AF and HF has not been clarified and, therefore, remains an area of research interest. The choice of optimal treatment is a challenge for AF and HF. Control of rate or rhythm is the most important decision for physicians. New tactics for budgeting and centralized monitoring may have an exciting effect on stroke occurrence...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27867527/the-cha2ds2-vasc-score-as-a-predictor-of-high-mortality-in-hospitalized-heart-failure-patients
#7
Akiomi Yoshihisa, Shunsuke Watanabe, Yuki Kanno, Mai Takiguchi, Akihiko Sato, Tetsuro Yokokawa, Shunsuke Miura, Takeshi Shimizu, Satoshi Abe, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Nobuo Sakamoto, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-Ichi Saitoh, Yasuchika Takeishi
AIMS: Atrial fibrillation (AF) is common in patients with heart failure (HF). CHA2DS2-VASc score was originally employed as a risk assessment tool for stroke in patients with AF; however, it has recently been used to predict not only stroke but also various cardiovascular diseases beyond the original AF field. We aimed to verify the CHA2DS2-VASc score as a risk assessment tool to predict mortality in patients with HF. METHODS AND RESULTS: Consecutive 1011 patients admitted for treatment of HF were divided into three groups based on their CHA2DS2-VASc scores: score 1-3 group (n = 317), score 4-6 group (n = 549) and score 7-9 group (n = 145)...
December 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27860070/cha2-ds2-vasc-score-predicts-unsuccessful-electrical-cardioversion-in-patients-with-persistent-atrial-fibrillation
#8
Elzbieta Mlodawska, Anna Tomaszuk-Kazberuk, Paulina Lopatowska, Marcin Kaminski, Wlodzimierz Jerzy Musial
BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia occurring in 2% of the population. It is known that AF increases morbidity and limited quality of life. The CHA2 DS2 VASc score is widely used to assess thrombotic complications. The CHA2 DS2 VAS score was not used till now in predicting effectiveness of electrical cardioversion. AIM: The aim of the study was to assess the value of CHA2 DS2 VASc score in predicting unsuccessful electrical cardioversion...
November 9, 2016: Internal Medicine Journal
https://www.readbyqxmd.com/read/27858918/global-longitudinal-strain-predicts-incident-atrial-fibrillation-and-stroke-occurrence-after-acute-myocardial-infarction
#9
Flemming Javier Olsen, Sune Pedersen, Jan Skov Jensen, Tor Biering-Sørensen
Patients with acute myocardial infarction are at increased risk of developing atrial fibrillation. We aimed to evaluate whether speckle tracking echocardiography improves risk stratification for atrial fibrillation in these patients.The study comprised of 373 patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention. Patients had an echocardiogram performed at a median of 2 days after their STEMI. The echocardiograms consisted of conventional measurements and myocardial strain analysis by speckle tracking from 3 apical projections...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27846282/external-validation-of-a-case-mix-adjustment-model-for-the-standardized-reporting-of-30-day-stroke-mortality-rates-in-china
#10
Ping Yu, Yuesong Pan, Yongjun Wang, Xianwei Wang, Liping Liu, Ruijun Ji, Xia Meng, Jing Jing, Xu Tong, Li Guo, Yilong Wang
BACKGROUND AND PURPOSE: A case-mix adjustment model has been developed and externally validated, demonstrating promise. However, the model has not been thoroughly tested among populations in China. In our study, we evaluated the performance of the model in Chinese patients with acute stroke. METHODS: The case-mix adjustment model A includes items on age, presence of atrial fibrillation on admission, National Institutes of Health Stroke Severity Scale (NIHSS) score on admission, and stroke type...
2016: PloS One
https://www.readbyqxmd.com/read/27837151/atrial-fibrillation-progression-of-coronary-atherosclerosis-and-myocardial-infarction
#11
Ozgur Bayturan, Rishi Puri, E Murat Tuzcu, Mingyuan Shao, Kathy Wolski, Paul Schoenhagen, Samir Kapadia, Steven E Nissen, Prashanthan Sanders, Stephen J Nicholls
BACKGROUND: Despite atrial fibrillation representing an established risk factor for stroke, the association between atrial fibrillation and both progression of coronary atherosclerosis and major adverse cardiovascular events is not well characterized. We assessed the serial measures of coronary atheroma burden and cardiovascular outcomes in patients with and without atrial fibrillation. METHODS: Data were analyzed from nine clinical trials involving 4966 patients with coronary artery disease undergoing serial intravascular ultrasonography at 18-24 month intervals to assess changes in percent atheroma volume (PAV)...
November 11, 2016: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/27826338/is-syntax-score-predictive-of-atrial-fibrillation-after-on-pump-coronary-artery-bypass-graft-surgery
#12
Levent Cerit, Hamza Duygu, Kamil Gulsen, Hatice S Kemal, Barcın Ozcem, Ozlem Balcioglu, Aziz Gunsel, Ozgur Tosun, Volkan Emren
BACKGROUND AND OBJECTIVES: The relationship of synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score and development of atrial fibrillation (AF) after coronary artery bypass surgery (CABG) has not been studied. Therefore, we assessed the relationship between the SYNTAX score and development of AF after CABG (POAF). SUBJECTS AND METHODS: The medical records of consecutive patients, who underwent CABG surgery from January 2013 to September 2015, were retrospectively reviewed for the development of AF in the postoperative period...
November 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27823686/how-well-does-physician-risk-assessment-predict-stroke-and-bleeding-in-atrial-fibrillation-results-from-the-outcomes-registry-for-better-informed-treatment-of-atrial-fibrillation-orbit-af
#13
Benjamin A Steinberg, Peter Shrader, Sunghee Kim, Laine Thomas, Gregg C Fonarow, Jack Ansell, Peter R Kowey, Daniel E Singer, Bernard J Gersh, Kenneth W Mahaffey, Eric D Peterson, Jonathan P Piccini
BACKGROUND: Assessments of stroke and bleeding risks are essential to selecting oral anticoagulation in patients with atrial fibrillation (AF). We aimed to assess outcomes according to physician assessed risk, with comparison to empirical risk scores. METHODS: This was a prospective, observational study of 9,715 outpatients with AF enrolled in ORBIT-AF, a US national registry. Stroke and bleeding risks were quantified by physician assignment, CHADS2 and CHA2DS2-VASc stroke scores, and ATRIA and HAS-BLED bleeding scores...
November 2016: American Heart Journal
https://www.readbyqxmd.com/read/27819149/clinical-relevance-of-pharmacokinetic-and-pharmacodynamic-properties-of-edoxaban-when-treating-patients-with-atrial-fibrillation-and-heart-failure
#14
Nadia Aspromonte, Furio Colivicchi
Atrial fibrillation (AF) is an independent risk factor for stroke. It is most prevalent in the elderly and frequently coexists with heart failure (HF). The joint occurrence of AF and HF further worsens prognosis. The prevention of thromboembolism is crucial in the management of AF. In recent years, new oral anticoagulants (NOACs) have been licensed for the prevention of stroke and systemic embolism in patients with AF. Areas covered: This article reviews the key published studies on the pharmacology, clinical efficacy and safety of edoxaban, the latest NOAC to receive approval for the AF indication...
November 6, 2016: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/27817212/the-factor-xa-inhibitor-edoxaban-for-the-prevention-of-stroke-and-systemic-embolism-in-patients-with-atrial-fibrillation
#15
Joan Minguet, Helen M Sims, Katherine H Smith, Peter Bramlage
With the rising prevalence of nonvalvular atrial fibrillation (NVAF) in the general population, the development of new drugs for prevention of thromboembolic events is essential. Non-vitamin K antagonist oral anticoagulants (NOACs) have been shown to present a number of advantages over conventionally used agents, such as predictable pharmacokinetics and no requirement for continuous anticoagulant monitoring. The most recently approved NOAC for the NVAF indication is edoxaban. Several subgroup analyses from the edoxaban phase III ENGAGE AF-TIMI 48 trial have now been published, alongside meta-analysis data comparing the four currently approved NOACs...
November 17, 2016: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/27814760/clinical-predictors-of-seizure-recurrence-after-the-first-post-ischemic-stroke-seizure
#16
Hyeon Jin Kim, Kee Duk Park, Kyoung-Gyu Choi, Hyang Woon Lee
BACKGROUND: The number of patients suffering post-stroke seizure after ischemic stroke (PSSi) is quite considerable, especially because ischemic stroke is more prevalent than hemorrhage in the general population. This study aimed to determine the predicting factors for seizure recurrence in ischemic stroke survivors and develop a clinical scoring system for the prediction of risks for seizure recurrence after the first PSSi. METHODS: We reviewed 3792 ischemic stroke patients from the Ewha Stroke Registry...
November 5, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27811208/application-of-biomarkers-for-risk-stratification-in-patients-with-atrial-fibrillation
#17
REVIEW
Ziad Hijazi, Jonas Oldgren, Agneta Siegbahn, Lars Wallentin
BACKGROUND: Atrial fibrillation is the most common sustained arrhythmia and an important contributor to cardiovascular morbidity and mortality. Several strategies have been proposed for prediction of outcomes and individualization of treatments to better balance the benefits of stroke prevention and risks of bleeding during anticoagulation. CONTENT: The availability of analytically more specific and sensitive methods to measure circulating biomarkers of cellular and organ stress and dysfunction has led to testing of their utility in several cardiovascular conditions...
November 3, 2016: Clinical Chemistry
https://www.readbyqxmd.com/read/27809773/electrocardiographic-and-echocardiographic-predictors-of-paroxysmal-atrial-fibrillation-detected-after-ischemic-stroke
#18
Maria A Baturova, Seth H Sheldon, Jonas Carlson, Peter A Brady, Grace Lin, Alejandro A Rabinstein, Paul A Friedman, Pyotr G Platonov
BACKGROUND: Detection of atrial fibrillation after ischemic stroke is challenging due to its paroxysmal nature. We aimed to assess predictors of paroxysmal atrial fibrillation using non-invasive surface ECG and transthoracic echocardiography to select candidates for atrial fibrillation screening. METHODS: Ischemic stroke patients without documented atrial fibrillation (n = 110, 67 ± 10 years, 40 female) and a control group of age- and gender-matched patients with history of paroxysmal atrial fibrillation prior to stroke (n = 55, 67 ± 10 years, 19 female) comprised the study sample...
November 3, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27797891/use-of-oral-anticoagulation-in-the-management-of-atrial-fibrillation-in-patients-with-esrd-con
#19
Vaibhav Keskar, Manish M Sood
Among patients with atrial fibrillation, prophylaxis for stroke prevention with the use of anticoagulation is well established in the general population. A number of randomized controlled trials and evidence-based risk prediction tools clearly delineate the benefit and risks of therapy. Despite the high incidence of atrial fibrillation in the late stage CKD and ESRD populations, little high quality evidence exists in these populations. Is it appropriate then to extrapolate findings from the general population to those with CKD/ESRD? In our view, too much uncertainty exists regarding proof of efficacy with clear signals of harm...
November 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27794212/brachial-ankle-pulse-wave-velocity-is-associated-with-3-month-functional-prognosis-after-ischemic-stroke
#20
Kentaro Ishizuka, Takao Hoshino, Satoru Shimizu, Yuka Shirai, Satoko Mizuno, Sono Toi, Kenji Maruyama, Shinichiro Uchiyama, Kazuo Kitagawa
BACKGROUND AND AIMS: Brachial-ankle pulse wave velocity (baPWV) is a good measure of arterial stiffness and is associated with risk of future vascular events. The present study aimed to examine whether baPWV can also predict 3-month functional outcome after stroke. METHODS: This hospital-based study included 327 consecutive patients with acute ischemic stroke and in whom baPWV was measured during hospitalization. We defined good and poor functional outcomes as a modified Rankin Scale score of <3 and ≥ 3 at 3 months, respectively, after initial stroke...
August 26, 2016: Atherosclerosis
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