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https://www.readbyqxmd.com/read/29329888/associations-between-cartilage-proteoglycan-density-and-patient-outcomes-12months-following-anterior-cruciate-ligament-reconstruction
#1
Brian Pietrosimone, Daniel Nissman, Darin A Padua, J Troy Blackburn, Matthew S Harkey, Robert A Creighton, Ganesh M Kamath, Kaitlin Healy, Randy Schmitz, Jeffrey B Driban, Steve W Marshall, Joanne M Jordan, Jeffrey T Spang
BACKGROUND: Lower proteoglycan density (PGD) of the articular cartilage may be an early marker of osteoarthritis following anterior cruciate ligament (ACL) reconstruction (ACL-R). The purpose this study was to determine associations between the Knee Injury and Osteoarthritis Outcomes Score (KOOS) and PGD of the articular cartilage in the femur and tibia 12-months following ACL-R. METHODS: We evaluated KOOS pain, symptoms, function in activities of daily living (ADL), function in sport and recreation (Sport), and quality of life (QOL), as well as PGD using T1rho magnetic resonance imaging in 18 individuals 12...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29326899/effectiveness-of-a-multimodal-exercise-rehabilitation-program-on-walking-capacity-and-functionality-after-a-stroke
#2
Montserrat Grau Pellicer, Andrés Chamarro Lusar, Josep Medina Casanovas, Bernat-Carles Serdà Ferrer
The aim of this study was to determine the effectiveness of a 12-week multimodal exercise rehabilitation program on walking speed, walking ability and activities of daily living (ADLs) among people who had suffered a stroke. Thirty-one stroke survivors who had completed a conventional rehabilitation program voluntarily participated in the study. Twenty-six participants completed the multimodal exercise rehabilitation program (2 days/wk, 1 hr/session). Physical outcome measures were: walking speed (10-m walking test), walking ability (6-min walking test and functional ambulation classification) and ADLs (Barthel Index)...
December 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29325993/serum-haptoglobin-in-chinese-patients-with-alzheimer-s-disease-and-mild-cognitive-impairment-a-case-control-study
#3
Cen-Jing Zhu, Guo-Xin Jiang, Jin-Mei Chen, Zhi-Ming Zhou, Qi Cheng
BACKGROUND: Serum level of Haptoglobin (Hp) maybe associated with Alzheimer's disease (AD) and mild cognitive impairment (MCI). OBJECTIVE: To investigate associations between serum Hp and AD, as well as between Hp and MCI. METHODS: Serum levels of Hp were measured and analyzed for 51 patients with AD, 139 patients with MCI and their healthy controls matched with sex and age. All study subjects were from a survey among residents aged 60 years and over in a community located in the southwest suburb of Shanghai...
January 8, 2018: Brain Research Bulletin
https://www.readbyqxmd.com/read/29324411/virtual-activities-of-daily-living-for-recovery-of-upper-extremity-motor-function
#4
Richard J Adams, Matthew D Lichter, Allison Ellington, Marga White, Kate Armstead, James T Patrie, Paul T Diamond
A study was conducted to investigate the effectiveness of virtual activities of daily living (ADL) practice using the SaeboVR software system for the recovery of upper extremity (UE) motor function following stroke. The system employs Kinect sensor-based tracking to translate human UE motion into the anatomical pose of the arm of the patient's avatar within a virtual environment, creating a virtual presence within a simulated task space. Patients gain mastery of 12 different integrated activities while traversing a metaphorical "road to recovery" that includes thematically linked levels and therapist-selected difficulty settings...
January 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29322869/identifying-organizing-and-prioritizing-ideas-on-how-to-enhance-adl-ability
#5
Kristina Tomra Nielsen, Louise Klokker, Susanne Guidetti, Eva Ejlersen Wæhrens
BACKGROUND: There is a need to develop evidence-based occupational therapy programs aiming at enhancing the ability to perform Activities of Daily Living (ADL) among persons living with chronic conditions. Information from different sources is to be integrated in the development process. Thus, it is necessary to engage both occupational therapists and persons living with chronic conditions in suggesting ideas on how to enhance the ADL ability. OBJECTIVE: To identify, organize and prioritize ideas on how to enhance ability to perform ADL in persons with chronic conditions...
January 11, 2018: Scandinavian Journal of Occupational Therapy
https://www.readbyqxmd.com/read/29321439/the-association-of-bite-instability-and-comorbidities-in-elderly-people
#6
Susumu Itakura, Masaaki Miyata, Atsushi Kuroda, Manabu Setoguchi, Atsushi Kusumoto, Daisuke Hokonohara, Mitsuru Ohishi
Objective The purpose was to evaluate the association between bite instability and comorbidities, comprehensive geriatric evaluations, or disabilities in elderly people. Methods A dentist examined the oral function, such as the bite stability, number of teeth, and the use of dentures, in 119 patients (93 women, mean age: 86.7±7.8) in 2 nursing homes for the elderly. The association between the oral function and the prevalence of diseases, including hypertension, diabetes mellitus, and dementia, was analyzed...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29316721/predictors-of-a-change-and-correlation-in-activities-of-daily-living-after-hip-fracture-in-elderly-patients-in-a-community-hospital-in-poland-a-six-month-prospective-cohort-study
#7
Maria Ganczak, Krzysztof Chrobrowski, Marcin Korzeń
OBJECTIVES: The consequences of hip fractures (HFs) in elderly persons include a deterioration in functional capacity to perform activities that enable independent living. Since prior research into this issue in Central Europe is rather scant, this study sought to assess the change in activities and instrumental activities of daily living (ADL/IADL) after HF surgery among Polish patients, to study predictors of regaining pre-fracture functional status three and six months later, and to evaluate the correlation between ADL and IADL limitations over time...
January 8, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29316334/geriatric-assessment-of-physical-and-cognitive-functioning-in-a-diverse-cohort-of-systemic-lupus-erythematosus-patients-a-pilot-study
#8
Laura Plantinga, Benjamin D Tift, Charmayne Dunlop-Thomas, S Sam Lim, C Barrett Bowling, Cristina Drenkard
OBJECTIVE: To use multi-domain functional assessment, commonly performed in geriatric patients but novel among SLE patients, to better understand functional impairment in SLE. METHODS: We recruited 60 adult participants [aged 20-39 (26.7%), 40-59 (50.0%), and ≥60 (23.3%); 80.0% black; 90.0% female] from an existing cohort of SLE patients. During in-person visits (10/16-4/17), we evaluated physical performance (range 0-4; higher scores = better performance); cognitive performance (five fluid cognition domains; adjusted t-scores); and self-reported measures including physical functioning (t-scores), activities of daily living (ADLs), falls, and life-space mobility...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29315459/pretherapeutic-functional-neuroimaging-predicts-tremor-arrest-after-thalamotomy
#9
C Tuleasca, E Najdenovska, J Régis, T Witjas, N Girard, J Champoudry, M Faouzi, J-P Thiran, M Bach Cuadra, M Levivier, D Van De Ville
OBJECTIVE: Essential tremor (ET) represents the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic procedures (deep brain stimulation or radiofrequency thalamotomy) or alternatively minimally invasive high-focused ultrasound or radiosurgery. All aim at same target, thalamic ventro-intermediate nucleus (Vim). METHODS: The study included a cohort of 17 consecutive patients, with ET, treated only with left unilateral stereotactic radiosurgical thalamotomy (SRS-T) between September 2014 and August 2015...
January 7, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29315350/gluteal-muscle-damage-leads-to-higher-in-vivo-hip-joint-loads-3-months-after-total-hip-arthroplasty
#10
Philipp Damm, Jip Zonneveld, Sophie Brackertz, Florian Streitparth, Tobias Winkler
BACKGROUND: Total hip arthroplasty (THA) is in most cases improving patients´ life quality immediately after surgery. However, a closer look at these patients, especially with modern gait analysis methods, reveals also negative consequences due to the surgical approach related injury to the pelvic muscles. We hypothesized that this damage will have a negative impact on hip joint contact forces during activities of daily living (ADL). METHODS: 10 patients undergoing THA received an instrumented hip joint implant enabling real time in vivo measurements of hip joint loads using a direct lateral approach...
2018: PloS One
https://www.readbyqxmd.com/read/29315232/recognition-of-activities-of-daily-living-based-on-environmental-analyses-using-audio-fingerprinting-techniques-a-systematic-review
#11
REVIEW
Ivan Miguel Pires, Rui Santos, Nuno Pombo, Nuno M Garcia, Francisco Flórez-Revuelta, Susanna Spinsante, Rossitza Goleva, Eftim Zdravevski
An increase in the accuracy of identification of Activities of Daily Living (ADL) is very important for different goals of Enhanced Living Environments and for Ambient Assisted Living (AAL) tasks. This increase may be achieved through identification of the surrounding environment. Although this is usually used to identify the location, ADL recognition can be improved with the identification of the sound in that particular environment. This paper reviews audio fingerprinting techniques that can be used with the acoustic data acquired from mobile devices...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29315169/health-benefits-of-an-innovative-exercise-program-for-mitochondrial-disorders
#12
Carmen Fiuza-Luces, Jorge Díez-Bermejo, Miguel Fernández-de la Torre, Gabriel Rodríguez-Romo, Paz Sanz-Ayán, Aitor Delmiro, Diego Munguía-Izquierdo, Irene Rodríguez-Gómez, Ignacio Ara, Cristina Domínguez-González, Joaquín Arenas, Miguel A Martín, Alejandro Lucia, María Morán
PURPOSE: We determined the effects of an innovative 8-week exercise intervention (aerobic, resistance and inspiratory muscle training) for patients with mitochondrial disease (MD). METHODS: Several endpoints were assessed in 12 patients (19-59 years, 4 female) at pre-training, post-training and after 4-week detraining: aerobic power, muscle strength/power and maximal inspiratory pressure (main endpoints), ability to perform activities of daily living (ADL), body composition, quality of life and blood myokines (secondary endpoints)...
January 8, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29308748/different-degree-of-immune-recovery-using-antiretroviral-regimens-with-vonavir-or-zidovudine-lamivudine-and-efavirenz-in-patients-receiving-first-line-treatment-in-iran
#13
Leila Sadeghi, Samaneh Moallemi, Reza Adl Tabatabai, Reza Adl Tabatabai, Ali Esmaeilzadeh, Sara Ahsani-Nasab, Niloofar Eghbal Ahmadi, Saeed Bayanolhagh, Mahin Lolaie, Arsalan Narouei, Ahmad Alinaghi, Minoo Mohraz
The initial ART regimens used by most national treatment guidelines in resource-limited settings include 2 nucleoside reverse-transcriptase inhibitors (NRTIs) and 1 non-nucleoside reverse-transcriptase inhibitor (NNRTI). The NRTIshave consistedof Zidovudine (AZT) or Stavudine (d4T) with Lamivudine (3TC); the NNRTI component hasbeen Nevirapine (NVP) or Efavirenz (EFV). There exists few data indicating if Vonavir is more effective in increasing CD4+ T cell counts or other first-line drugs of ART.Immunological outcomes of 134 individuals who just started antiretroviral therapy with Vonavir or Zidovudine/Lamivudine and Efavirenzanalyzed...
January 7, 2018: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/29307560/the-association-between-objectively-measured-physical-activity-depression-cognition-and-health-related-quality-of-life-in-parkinson-s-disease
#14
Janet M T van Uem, Bernhard Cerff, Malte Kampmeyer, Jos Prinzen, Menno Zuidema, Markus A Hobert, Susanne Gräber, Daniela Berg, Walter Maetzler, Inga Liepelt-Scarfone
BACKGROUND: Lower levels of physical activity are associated with lower Health-Related Quality of Life (HRQoL) in Parkinson's disease (PD). We evaluated the influence of quantitative physical activity parameters among other (disease-related) features representing other domains of the WHO International model for classification of Function, Disability, and Health (ICF) on HRQoL in PD. METHODS: Home-based movement data (DynaPort MiniMod®) was collected in 47 PD patients...
December 23, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29307083/in-thai-nationals-the-apoe4-allele-affects-multiple-domains-of-neuropsychological-biobehavioral-and-social-functioning-thereby-contributing-to-alzheimer-s-disorder-while-the-apoe3-allele-protects-against-neuropsychiatric-symptoms-and-psychosocial-deficits
#15
Sookjaroen Tangwongchai, Thitiporn Supasitthumrong, Solaphat Hemrunroj, Chavit Tunvirachaisakul, Phenphichcha Chuchuen, Natnicha Houngngam, Thiti Snabboon, Ittipol Tawankanjanachot, Yuthachai Likitchareon, Kamman Phanthumchindad, Michael Maes
The apolipoprotein E epsilon 4 (ApoE4) allele is the strongest genetic risk factor for Alzheimer's disorder (AD) and is associated with semantic and episodic memory deficits. The aim of this study was to examine the associations between ApoE alleles (E2, E3, E4) and genotypes and neuropsychological tests, behavioral functions, and dementia symptoms as assessed using Consortium to Establish a Registry for Alzheimer's Disease (CERAD). This study included 60 patients with Alzheimer's disorder (AD), 60 with mild cognitive disorder (MCI), and 62 normal volunteers...
January 6, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29304204/death-depression-disability-and-dementia-associated-with-self-reported-hearing-problems-a-25-year-study
#16
Hélène Amieva, Camille Ouvrard, Céline Meillon, Laetitia Rullier, Jean-François Dartigues
Background: Hearing loss in older adults is suspected to play a role in social isolation, depression, disability, lower quality of life and risk of dementia. Such suspected associations still need to be consolidated with additional research. With a particularly long follow-up, this study assessed the relationship between hearing status and four major adverse health events: death, dementia, depression, and disability. Methods: Prospective community-based study of 3777 subjects aged ≥ 65 followed-up for 25 years...
January 3, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29301463/hospitalization-associated-disability-in-older-adults-with-valvular-heart-disease-incidence-risk-factors-and-its-association-with-care-processes
#17
Maren Jonckers, Bastiaan Van Grootven, Ester Willemyns, Miek Hornikx, Anthony Jeuris, Christophe Dubois, Marie-Christine Herregods, Mieke Deschodt
BACKGROUND: The aim of this study was to determine the incidence and recovery of hospitalisation-associated disability (HAD), the associated risk factors, and the link with care processes in patients aged 70 years or older hospitalised with valvular heart disease (VHD). METHODS: Prospective cohort study performed on the cardiology and cardiac surgery units of University Hospitals Leuven, Belgium. HAD was defined as the loss of independence to complete one of the Activities of Daily Living (ADLs) between hospital admission and discharge...
January 4, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29300435/orthostatic-hypotension-and-associated-factors-among-home-care-clients-aged-75-years-or-older-a-population-based-study
#18
A Luukkonen, M Tiihonen, T Rissanen, S Hartikainen, I Nykänen
OBJECTIVES: The aim of this study was to examine orthostatic hypotension (OH) and associated factors among home care clients aged 75 years or older. DESIGN: Non-randomised controlled study. SETTING AND PARTICIPANTS: The study sample included 244 home care clients aged 75 years or older living in Eastern and Central Finland. MEASUREMENTS: Nurses, nutritionists and pharmacists collected clinical data including orthostatic blood pressure, depressive symptoms (15-item Geriatric Depression Scale GDS-15), nutritional status (Mini Nutritional Assessment MNA), drug use, self-rated health, daily activities (Barthel ADL Index and Lawton and Brody IADL scale) and self-rated ability to walk 400 metres...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29300429/dysphagia-in-hospitalized-older-patients-associated-factors-and-nutritional-interventions
#19
D Eglseer, R J G Halfens, J M G A Schols, C Lohrmann
OBJECTIVES: To (1) assess the association between dysphagia and malnutrition as well as other related factors and (2) investigate the nutritional interventions that are initiated in dysphagic older patients. DESIGN: Cross-sectional, multi-center point prevalence measurement. SETTING: 53 Austrian hospitals. PARTICIPANTS: 3174 hospitalized patients, 65 years or older. MEASUREMENTS: A standardized and tested questionnaire was used for the data collection, which was based on both inspections of the patients and information documented in the patient chart...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29299751/risk-factors-for-unplanned-discontinuation-of-scheduled-treatment-in-elderly-patients-with-castration-resistant-prostate-cancer-results-of-the-ibutu-study
#20
Friedemann Honecker, Ulrich Wedding, Gerd Kallischnigg, Axel Schroeder, Jörg Klier, Thomas Frangenheim, Lothar Weißbach
PURPOSE: To gain knowledge about the factors associated with discontinuation of scheduled treatment in elderly men with castration-resistant prostate cancer (CRPC). METHODS: Patients ≥ 70 years with CRPC starting a new line of treatment were included in a prospective cohort study. A geriatric assessment (CGA) was performed at baseline, including comorbidity, mobility, functional/mental/nutritional status, as well as depression. Furthermore, pain intensity, quality of life, ECOG-performance status, and physicians' and patients' perception of health were documented...
January 4, 2018: Journal of Cancer Research and Clinical Oncology
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