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https://www.readbyqxmd.com/read/29145100/environmental-assessment-of-microwaves-and-the-effect-of-european-energy-efficiency-and-waste-management-legislation
#1
Alejandro Gallego-Schmid, Joan Manuel F Mendoza, Adisa Azapagic
More than 130 million microwaves are affected by European Union (EU) legislation which is aimed at reducing the consumption of electricity in the standby mode ('Standby Regulation') and at more sustainable management of end-of-life electrical and electronic waste ('WEEE Directive'). While legislation focuses on these two life cycle stages, there is little information on the environmental impacts of the entire life cycle of microwaves. To address this gap, this paper presents a comprehensive life cycle assessment of microwaves and assesses the environmental implications of the Standby Regulation and the WEEE Directive at the EU level...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29144139/a-multiscale-simulation-platform-linking-lithium-ion-battery-electrode-fabrication-process-with-performance-at-the-cell-level
#2
Alain Ngandjong, Alexis Rucci, Mariem Maiza, Garima Shukla, Jorge Gabriel Vazquez-Arenas, Alejandro A Franco
A novel multiscale modeling platform is proposed to demonstrate the importance of particle assembly during battery electrode fabrication by showing its effect on battery performance. For the first time, a discretized 3D electrode resulting from the simulation of its fabrication, has been incorporated within a 3D continuum performance model. The study used LiNiMnCoO2 as active material where effect of change of electrode formulation is explored for three cases, namely 85:15, 90:10, and 95:5, as ratios between active material and carbon-binder domains...
November 16, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29143599/epistasis-physical-capacity-related-genes-and-exceptional-longevity-fndc5-gene-interactions-with-candidate-genes-foxoa3-and-apoe
#3
Noriyuki Fuku, Roberto Díaz-Peña, Yasumichi Arai, Yukiko Abe, Hirofumi Zempo, Hisashi Naito, Haruka Murakami, Motohiko Miyachi, Carlos Spuch, José A Serra-Rexach, Enzo Emanuele, Nobuyoshi Hirose, Alejandro Lucia
BACKGROUND: Forkhead box O3A (FOXOA3) and apolipoprotein E (APOE) are arguably the strongest gene candidates to influence human exceptional longevity (EL, i.e., being a centenarian), but inconsistency exists among cohorts. Epistasis, defined as the effect of one locus being dependent on the presence of 'modifier genes', may contribute to explain the missing heritability of complex phenotypes such as EL. We assessed the potential association of epistasis among candidate polymorphisms related to physical capacity, as well as antioxidant defense and cardiometabolic traits, and EL in the Japanese population...
November 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29143597/genotypic-and-phenotypic-features-of-all-spanish-patients-with-mcardle-disease-a-2016-update
#4
Alfredo Santalla, Gisela Nogales-Gadea, Alberto Blázquez Encinar, Irene Vieitez, Adrian González-Quintana, Pablo Serrano-Lorenzo, Inés García Consuegra, Sara Asensio, Alfonsina Ballester-Lopez, Guillem Pintos-Morell, Jaume Coll-Cantí, Helios Pareja-Galeano, Jorge Díez-Bermejo, Margarita Pérez, Antoni L Andreu, Tomàs Pinós, Joaquín Arenas, Miguel A Martín, Alejandro Lucia
BACKGROUND: We recently described the genotype/phenotype features of all Spanish patients diagnosed with McArdle disease as of January 2011 (n = 239, prevalence of ~1/167,000) (J Neurol Neurosurg Psychiatry 2012;83:322-8). Several caveats were however identified suggesting that the prevalence of the disease is actually higher. METHODS: We have now updated main genotype/phenotype data, as well as potential associations within/between them, of all Spanish individuals currently diagnosed with McArdle disease (December 2016)...
November 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29143593/preface-genomics-and-biology-of-exercise-is-undergoing-a-paradigm-shift
#5
EDITORIAL
Nir Eynon, Sarah Voisin, Alejandro Lucia, Guan Wang, Yannis Pitsiladis
No abstract text is available yet for this article.
November 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29143569/prevalence-of-temporomandibular-symptoms-and-parafunctional-habits-in-a-university-dental-clinic-and-association-with-gender-age-and-missing-teeth
#6
Georgios S Chatzopoulos, Miguel Sanchez, Alejandro Cisneros, Larry F Wolff
Objective To assess the prevalence of symptoms of temporomandibular disorder (TMD) and parafunctional habits as well as to investigate their association with age, gender, and number of missing teeth. Methods This retrospective study is based on 4204 randomly selected patients who were examined to determine their symptoms of TMD, such as clicking, difficulty chewing, difficulty opening/closing, as well self-reported joint pain and parafunctional habits. Results Clenching/grinding was reported by 26.5% of the examined population, clicking by 14...
November 16, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29143226/aligned-ovine-diaphragmatic-myoblasts-overexpressing-human-connexin-43-seeded-on-poly-l-lactic-acid-scaffolds-for-potential-use-in-cardiac-regeneration
#7
Carlos Sebastián Giménez, Paola Locatelli, Florencia Montini Ballarin, Alejandro Orlowski, Ricardo A Dewey, Milagros Pena, Gustavo Abel Abraham, Ernesto Alejandro Aiello, María Del Rosario Bauzá, Luis Cuniberti, Fernanda Daniela Olea, Alberto Crottogini
Diaphragmatic myoblasts (DMs) are precursors of type-1 muscle cells displaying high exhaustion threshold on account that they contract and relax 20 times/min over a lifespan, making them potentially useful in cardiac regeneration strategies. Besides, it has been shown that biomaterials for stem cell delivery improve cell retention and viability in the target organ. In the present study, we aimed at developing a novel approach based on the use of poly (L-lactic acid) (PLLA) scaffolds seeded with DMs overexpressing connexin-43 (cx43), a gap junction protein that promotes inter-cell connectivity...
November 15, 2017: Cytotechnology
https://www.readbyqxmd.com/read/29143194/the-role-of-crowding-in-parallel-search-peripheral-pooling-is-not-responsible-for-logarithmic-efficiency-in-parallel-search
#8
Anna Madison, Alejandro Lleras, Simona Buetti
Recent results from our laboratory showed that, in fixed-target parallel search tasks, reaction times increase in a logarithmic fashion with set size, and the slope of this logarithmic function is modulated by lure-target similarity. These results were interpreted as being consistent with a processing architecture where early vision (stage one) processes elements in the display in exhaustive fashion with unlimited capacity and with a limitation in resolution. Here, we evaluate the contribution of crowding to our recent logarithmic search slope findings, considering the possibility that peripheral pooling of features (as observed in crowding) may be responsible for logarithmic efficiency...
November 15, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29142984/the-combination-of-beta-blockers-and-renin-angiotensin-system-blockers-improves-survival-in-incident-hemodialysis-patients-a-propensity-matched-study
#9
José Luño, Javier Varas, Rosa Ramos, Ignacio Merello, Pedro Aljama, Alejandro MartinMalo, Julio Pascual, Manuel Praga
Introduction: Although several studies suggest that the prognosis of hypertensive dialysis patients can be improved by using antihypertensive drug therapy, it is unknown whether the prescription of a particular class or combination of antihypertensive drugs is beneficial during hemodialysis. Methods: We performed a propensity score matching study to compare the effectiveness of various classes of antihypertensive drugs on cardiovascular (CV) mortality in 2518 incident hemodialysis patients in Spain...
July 2017: KI Reports
https://www.readbyqxmd.com/read/29142777/-trajectory-of-lumbar-and-sacral-pedicular-screws-comparison-between-midline-versus-wiltse-approach
#10
Martín Gagliardi, Alfredo Guiroy, Federico Fernández Molina, Francisco Fasano, Alejandro Morales Ciancio, Juan José Mezzadri, Pablo Jalón
Objectives: To compare the posterolateral Wiltse approach and conventional Midline approach in short lumbosacral fusions in terms of the angle of convergence of pedicle screws. Methods: We retrospectively reviewed computed tomography (CT) images of 76 lumbar and sacral pedicular screws that had been placed using a conventional midline approach (CA) (n = 38) and a Wiltse posterolateral approach (WA) (n = 38). All patients underwent short lumbosacral fusions from L3 to S1 for degenerative spinal disease...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29141910/munc13-proteins-control-regulated-exocytosis-in-mast-cells
#11
Elsa M Rodarte, Marco A Ramos, Alfredo J Davalos, Daniel C Moreira, David S Moreno, Eduardo I Cardenas, Alejandro I Rodarte, Youlia Petrova, Sofia Molina, Luis E Rendon, Elizabeth Sanchez, Keegan Breaux, Alejandro Tortoriello, John Manllo, Erika A Gonzalez, Michael J Tuvim, Burton F Dickey, Alan R Burns, Ruth Heidelberger, Roberto Adachi
Mast cells (MCs) are involved in host defenses against pathogen and inflammation. Stimulated MCs release substances stored in their granules via regulated exocytosis. In other cell types, Munc13 (mammalian homolog of C. elegans uncoordinated gene 13) proteins play essential roles in regulated exocytosis. Here, we found that MCs express Munc13-2 and -4, and studied their roles using global and conditional knockout (KO) mice. In a model of systemic anaphylaxis, we found no difference between WT and Munc13-2 KO mice, but global and MC-specific Munc13-4 KO mice developed less hypothermia...
November 15, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29141790/cerebral-toxoplasmosis-in-an-ms-patient-receiving-fingolimod
#12
Alejandro Enriquez-Marulanda, Jaime Valderrama-Chaparro, Laura Parrado, Juan Diego Vélez, Ana Maria Granados, Jorge Luis Orozco, Jairo Quiñones
Multiple Sclerosis (MS) is an autoimmune disease in which lymphocytes target putative myelin antigens in the CNS, causing inflammation and neurodegeneration. Fingolimod (FTY720) is an immunosuppressive drug used as a second line therapy for relapsing forms of MS due to its safety profile and good response to treatment. Despite its safety, there are still concerns about the possibility of Fingolimod being linked to the development of opportunistic infections like disseminated varicella zoster infections and herpes simplex encephalitis...
November 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29140978/adherence-to-inhaled-therapies-of-copd-patients-from-seven-latin-american-countries-the-lassyc-study
#13
Maria Montes de Oca, Ana Menezes, Fernando C Wehrmeister, Maria Victorina Lopez Varela, Alejandro Casas, Luis Ugalde, Alejandra Ramirez-Venegas, Laura Mendoza, Ana López, Filip Surmont, Marc Miravitlles
BACKGROUND: This study assessed the adherence profiles to inhaled therapies and the agreement between two patient self-report adherence methods in stable COPD lpatients from seven Latin American countries. METHODS: This observational, cross-sectional, multinational, multicenter study involved 795 COPD patients (post-bronchodilator forced expiratory volume in 1 second/forced vital capacity [FEV1/FVC] <0.70). Adherence to inhaled therapy was assessed using the specific Test of Adherence to Inhalers (10-item TAI) and the generic 8-item Morisky Medication Adherence Scale (MMAS-8) questionnaires...
2017: PloS One
https://www.readbyqxmd.com/read/29139587/metastatic-giant-malignant-phyllodes-tumor-of-the-breast
#14
Alejandro Martin Sanchez, Gianluca Franceschini, Danilo Di Giorgio, Riccardo Masetti
No abstract text is available yet for this article.
November 15, 2017: Breast Journal
https://www.readbyqxmd.com/read/29138239/expanding-the-chondroitin-glycoproteome-of-caenorhabditis-elegans
#15
Fredrik Noborn, Alejandro Gomez Toledo, Waqas Nasir, Jonas Nilsson, Tabea Dierker, Lena Kjellén, Göran Larson
Chondroitin sulfate proteoglycans (CSPGs) are important structural components of connective tissues in essentially all metazoan organisms. In vertebrates, CSPGs are involved also in more specialized processes such as neurogenesis and growth factor signaling. In invertebrates, however, knowledge of CSPGs core proteins and proteoglycan-related functions is relatively limited, even for Caenorhabditis elegans. This nematode produces large amounts of non-sulfated chondroitin in addition to low-sulfated chondroitin sulfate chains...
November 14, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29137926/effect-of-water-activity-and-temperature-on-the-growth-of-eurotium-species-isolated-from-animal-feeds
#16
Mariana Greco, Alejandro Pardo, Graciela Pose, Andrea Patriarca
BACKGROUND: Xerophilic fungi represent a serious problem due to their ability to grow at low water activities causing the spoiling of low and intermediate moisture foods, stored goods and animal feeds, with the consequent economic losses. AIMS: The combined effect of water activity and temperature of four Eurotium species isolated from animal feeds was investigated. METHODS: Eurotium amstelodami, Eurotium chevalieri, Eurotium repens and Eurotium rubrum were grown at 5, 15, 25, 37 and 45°C on malt extract agar adjusted with glycerol in the range 0...
November 11, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/29137641/improving-e-coli-growth-performance-by-manipulating-small-rna-expression
#17
REVIEW
Alejandro Negrete, Joseph Shiloach
Efficient growth of E. coli, especially for production of recombinant proteins, has been a challenge for the biotechnological industry since the early 1970s. By employing multiple approaches, such as different media composition, various growth strategies and specific genetic manipulations, it is now possible to grow bacteria to concentrations exceeding 100 g/L and to achieve high concentrations of recombinant proteins. Although the growth conditions are carefully monitored and maintained, it is likely that during the growth process cells are exposed to periodic stress conditions, created by fluctuations in pH, dissolved oxygen, temperature, glucose, and salt concentration...
November 14, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/29137137/a-comparison-of-fpga-and-gpgpu-designs-for-bayesian-occupancy-filters
#18
Luis Medina, Miguel Diez-Ochoa, Raul Correal, Sergio Cuenca-Asensi, Alejandro Serrano, Jorge Godoy, Antonio Martínez-Álvarez, Jorge Villagra
Grid-based perception techniques in the automotive sector based on fusing information from different sensors and their robust perceptions of the environment are proliferating in the industry. However, one of the main drawbacks of these techniques is the traditionally prohibitive, high computing performance that is required for embedded automotive systems. In this work, the capabilities of new computing architectures that embed these algorithms are assessed in a real car. The paper compares two ad hoc optimized designs of the Bayesian Occupancy Filter; one for General Purpose Graphics Processing Unit (GPGPU) and the other for Field-Programmable Gate Array (FPGA)...
November 11, 2017: Sensors
https://www.readbyqxmd.com/read/29137126/carbon-nanotubes-effect-on-mitochondrial-oxygen-flux-dynamics-polarography-experimental-study-and-machine-learning-models-using-star-graph-trace-invariants-of-raman-spectra
#19
Michael González-Durruthy, Jose M Monserrat, Bakhtiyor Rasulev, Gerardo M Casañola-Martín, José María Barreiro Sorrivas, Sergio Paraíso-Medina, Víctor Maojo, Humberto González-Díaz, Alejandro Pazos, Cristian R Munteanu
This study presents the impact of carbon nanotubes (CNTs) on mitochondrial oxygen mass flux (Jm) under three experimental conditions. New experimental results and a new methodology are reported for the first time and they are based on CNT Raman spectra star graph transform (spectral moments) and perturbation theory. The experimental measures of Jm showed that no tested CNT family can inhibit the oxygen consumption profiles of mitochondria. The best model for the prediction of Jm for other CNTs was provided by random forest using eight features, obtaining test R-squared (R²) of 0...
November 11, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29136673/endoscopic-full-thickness-resection-of-gastric-stromal-tumor-one-and-done
#20
Ming-Ming Xu, Alejandro Angeles, Michel Kahaleh
No abstract text is available yet for this article.
November 14, 2017: Endoscopy
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