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Long-term survival of trauma patients

Mathilde Chevignard, Leila Francillette, Hanna Toure, Dominique Brugel, Philippe Meyer, Anne Laurent Vannier, Marion Opatowski, Laurence Watier
OBJECTIVE: Childhood traumatic brain injury (TBI) is a leading cause of death and lifelong acquired disability. The aim of this study was to prospectively study intellectual ability following childhood severe TBI over 7-8years post-injury, and factors influencing outcome and change over time. MATERIAL/PATIENTS AND METHODS: Children (0-15years) consecutively admitted in a single trauma center for severe non-inflicted TBI over a 3-year period were included in a prospective longitudinal study...
September 2016: Annals of Physical and Rehabilitation Medicine
Sebastiano Castrovinci, Sam Emmanuel, Marco Moscarelli, Giacomo Murana, Giuseppa Caccamo, Emanuela Clara Bertolino, Giuseppe Nasso, Giuseppe Speziale, Khalil Fattouch
Aortic valve disease is a prevalent disorder that affects approximately 2% of the general adult population. Surgical aortic valve replacement is the gold standard treatment for symptomatic patients. This treatment has demonstrably proven to be both safe and effective. Over the last few decades, in an attempt to reduce surgical trauma, different minimally invasive approaches for aortic valve replacement have been developed and are now being increasingly utilized. A narrative review of the literature was carried out to describe the surgical techniques for minimally invasive aortic valve surgery and report the results from different experienced centers...
September 2016: Journal of Geriatric Cardiology: JGC
Krishnaraj Mahendraraj, Diane M Durgan, Ronald S Chamberlain
BACKGROUND: Although burn patients with preexisting mood disorders have been shown to have diminished clinical recovery, acute mental disorders (AMD) are often unrecognized despite a link with post-traumatic stress disorder and social maladjustment later on. This study assessed the clinical profile of a large cohort of burn patients who developed AMD compared to those with chronic mental illness (CMI) and those without mental health problems to assess the impact of AMI on burn outcomes...
August 28, 2016: Burns: Journal of the International Society for Burn Injuries
Alberto Repossini, Theodor Fischlein, Giuseppe Santarpino, Christina Schäfer, Benjamin Claus, Bruno Passaretti, Lorenzo Di Bacco, Laura Giroletti, Gianluigi Bisleri, Claudio Muneretto, Herko Grubitzsch
BACKGROUND: The Freedom Solo (FS) bovine pericardial valve (Sorin Group, Milan, Italy) is a stentless bioprosthesis that was introduced in 2004 and approved by the United States Food and Drug Administration in 2014. No long-term follow-up series are available to date. We report the multicenter experience of 4 European institutions that began implanting FS extensively from its introduction, providing the largest series with long-term follow-up. METHODS: From 2004 to 2009, 565 patients (242 women [42...
August 17, 2016: Annals of Thoracic Surgery
Hege Linnerud Fredø, Syed Ali Mujtaba Rizvi, Mehran Rezai, Pål Rønning, Bjarne Lied, Eirik Helseth
BACKGROUND: Patient selection for surgical treatment of subaxial cervical spine fractures (S-CS-fx) may be challenging and is dependent on fracture morphology, the integrity of the discoligamentous complex, neurological status, comorbidity, risks of surgery and the expected long-term outcomes. The purpose of this study is to evaluate complications and long-term outcomes in a consecutive series of 303 patients with S-CS-fx treated with open surgical fixation. METHODS: Medical charts were retrospectively reviewed...
2016: BMC Surgery
Kuen Lam, Man Fuk Leung, Chi Wai Kwan, Joseph Kwan
OBJECTIVE: The study aimed to examine the epidemiology of hypertonic contractures and its relationship with minimal trauma fracture (MTF), and to determine the incidence and predictors of (MTF) in long-term care residents. DESIGN: This was a longitudinal cohort study of prospectively collected data. Participants were followed from March 2007 to March 2016 or until death. SETTING: A 300-bed long-term care hospital in Hong Kong. PARTICIPANTS: All long-term care residents who were in need of continuous medical and nursing care for their activities of daily living...
August 9, 2016: Journal of the American Medical Directors Association
Takeshi Omori, Yoshiyuki Fujiwara, JeongHo Moon, Keijiro Sugimura, Hiroshi Miyata, Toru Masuzawa, Kentaro Kishi, Norikatsu Miyoshi, Akira Tomokuni, Hirofumi Akita, Hidenori Takahashi, Syougo Kobayashi, Masayoshi Yasui, Masayuki Ohue, Masahiko Yano, Masato Sakon
BACKGROUND: Single-incision laparoscopic surgery maximizes the advantages of laparoscopic surgery by reducing abdominal trauma; however, few comparative studies have addressed its role in gastric cancer. PURPOSE: This study sought to demonstrate the safety and feasibility of single-incision laparoscopic distal gastrectomy (SLDG) with radical D2 lymphadenectomy by comparing its short- and long-term outcomes with those of conventional multi-port laparoscopic surgery (MLDG)...
August 10, 2016: Annals of Surgical Oncology
Mary Kirkilas, David M Notrica, Crystal S Langlais, Jared T Muenzer, Jozef Zoldos, Kathleen Graziano
BACKGROUND: Vascular trauma in children, although rare, carries significant risk for repair. Here we report outcomes from a single trauma center for children with extremity vascular trauma, proximal to the digits. METHODS: Retrospective chart review of patients less than age 18years with an acute, non-iatrogenic traumatic arterial vascular injury of the upper and/or lower extremity between January 2008 and December 2013. Abstracted patient demographics, injury characteristics, surgical management, and disposition were summarized and compared with nonparametric methods...
November 2016: Journal of Pediatric Surgery
Jürgen W Schmitt, Christian Benden, Claudio Dora, Clément M L Werner
BACKGROUND: In recent years, the number of lung transplants has increased rapidly, with higher quality of life and improved survival rates in transplant recipients, including patients with advanced age. This, in turn, means that more transplant recipients will seek musculoskeletal care to treat degenerative joint disease and also trauma incidents. Safety concerns regarding elective and posttraumatic hip arthroplasty in transplant patients include an increased risk of infection, wound healing problems, periprosthetic fractures and loosening of the implants...
2016: Patient Safety in Surgery
Grace Chen, Jungshan Chang, Dachuan Zhang, Sandra Pinho, Jung-Eun Jang, Paul S Frenette
Vaso-occlusive crisis (VOC) is one of the most common complications of sickle cell disease (SCD). Recurrent episodes of VOC may cause irreversible organ damage and early mortality in patients with SCD. Emerging evidence suggests that VOC arises from a complex cascade that involves interactions among multiple blood and endothelial cells in the vasculature. Previous studies have identified αMβ2 integrin (Mac-1) as a critical molecule that mediates heterotypic interactions between red blood cells (RBCs) and adherent leukocytes and promotes VOC in SCD mice...
October 2016: Experimental Hematology
Andrew Salipas, Lara A Kimmel, Elton R Edwards, Sandeep Rakhra, Afshin Kamali Moaveni
BACKGROUND: Fractures of the medial third of the clavicle comprise less than 3% of all clavicle fractures. The natural history and optimal management of these rare injuries are unknown. The aim of our study is to describe the demographics, management and outcomes of patients with medial clavicle fractures treated at a Level 1 Trauma Centre. METHODS: A retrospective review was conducted of patients presenting to our institution between January 2008 and March 2013 with a medial third clavicle fracture...
June 6, 2016: Injury
Allan B Peetz, Gabriel A Brat, Jessica Rydingsward, Reza Askari, Olubode A Olufajo, Kevin M Elias, Kris M Mogensen, Jessica L Lesage, Clare M Horkan, Ali Salim, Kenneth B Christopher
BACKGROUND: The association between functional status in trauma survivors and long-term outcomes is unknown. METHODS: We performed an observational cohort study on adult trauma patients (≥18 years), who required admission to the intensive care unit and who survived hospitalization between 1997 and 2011. The exposure of interest was a functional status defined as bed mobility, transfers, and gait level assessed at the time of hospital discharge. Adjusted odds ratios were estimated by multivariable logistic regression models...
September 2016: Surgery
Xishan Wang
Colorectal surgery is rapidly developing in the direction of minimally invasive surgery and functional surgery. New technology and ideas are constantly emerging recently. Laparoscopic colon surgery has already been recommended by NCCN guideline. However, laparoscopic rectal cancer surgery still needs to wait for survival and recurrence rates of long-term follow-up data for verification. In recent years, with the rapid progression of imaging equipment of laparoscope, the new 3D laparoscopic system will process image more quickly, and surgeons can get space depth feeling like open surgery only with a pair of glasses...
June 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Qiuheng Zhang, Elaine F Reed
The development of post-transplantation antibodies against non-HLA autoantigens is associated with rejection and decreased long-term graft survival. Although our knowledge of non-HLA antibodies is incomplete, compelling experimental and clinical findings demonstrate that antibodies directed against autoantigens such as angiotensin type 1 receptor, perlecan and collagen, contribute to the process of antibody-mediated acute and chronic rejection. The mechanisms that underlie the production of autoantibodies in the setting of organ transplantation is an important area of ongoing investigation...
August 2016: Nature Reviews. Nephrology
Lars Folkestad, Jannie Dahl Hald, Vladimir Canudas-Romo, Jeppe Gram, Anne Pernille Hermann, Bente Langdahl, Bo Abrahamsen, Kim Brixen
Osteogenesis imperfecta (OI) is a hereditary connective tissue disease that causes frequent fractures. Little is known about causes of death and length of survival in OI. The objective of this work was to calculate the risk and cause of death, and the median survival time in patients with OI. This study was a Danish nationwide, population-based and register-based cohort study. We used National Patient Register data from 1977 until 2013 with complete long-term follow-up. Participants comprised all patients registered with the diagnosis of OI from 1977 until 2013, and a reference population matched five to one to the OI cohort...
June 27, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
W Mutschler, M Mutschler, M Graw, R Lefering
Long-term survival after severe trauma is rarely addressed in German trauma journals although knowledge of life expectancy and identification of factors contributing to increased mortality are important for lifetime care management, development of service models, and targeting health promotion and prevention interventions. As reliable data in Germany are lacking, we compiled data mainly from the USA and Australia to describe life expectancy, risk factors, and predictors of outcome in patients experiencing traumatic spinal cord injury, traumatic brain injury, and polytrauma...
July 2016: Der Unfallchirurg
M A Ayerza, N S Piuzzi, L A Aponte-Tinao, G L Farfalli, D L Muscolo
BACKGROUND: Structural allografts have been used to correct deformities or to fill bone defects secondary to tumor excisions, trauma, osteochondral lesions, or intercalary arthrodesis. However, the quality of published evidence supporting the use of allograft transplantation in foot and ankle surgery has been reported as fair. The purpose of this study was to report the overall survival of structural allograft in the foot and ankle after tumor resection, and the survival according to the type of allograft and the complication rates in the medium to long term...
August 2016: Musculoskeletal Surgery
Eduardo Martinez-Del-Campo, Jay D Turner, Leonardo Rangel-Castilla, Hector Soriano-Baron, Samuel Kalb, Nicholas Theodore
OBJECTIVE If left untreated, occipitocervical (OC) instability may lead to serious neurological injury or death. Open internal fixation is often necessary to protect the neurovascular elements. This study reviews the etiologies for pediatric OC instability, analyzes the radiographic criteria for surgical intervention, discusses surgical fixation techniques, and evaluates long-term postoperative outcomes based on a single surgeon's experience. METHODS The charts of all patients < 18 years old who underwent internal OC fixation conducted by the senior author were retrospectively reviewed...
June 10, 2016: Journal of Neurosurgery. Pediatrics
Bethany L Strong, Christina R Greene, Gordon S Smith
OBJECTIVES: The objectives of this study were to determine the association between recurrent trauma admissions (recidivism) and subsequent long-term mortality, and to identify those in most need for preventive interventions. BACKGROUND: Patients with a single intentional injury have been shown to have a higher risk of future injury mortality than those with unintentional injury with 5-year mortality rates as high as 20% being reported for recurrent penetrating trauma...
June 8, 2016: Annals of Surgery
Jordan D Bohnen, David C Chang, Elie P Ramly, Olubode A Olufajo, Ryan T Le, Haytham M A Kaafarani, D Dante Yeh, David R King, Peter J Fagenholz, Kathryn Butler, Reza Askari, Ali Salim, George C Velmahos, Marc de Moya
OBJECTIVE: The relationship between baseline (ie. pre-injury) blood pressure and trauma outcomes in elderly patients is unknown. We therefore aimed to identify the independent impact of baseline systolic blood pressure (SBP) on inpatient mortality amongst elderly trauma patients. METHODS: The 2004-2014 trauma registries of two Level I Trauma Centers were linked to electronic health records then reviewed to identify patients ≥65 years old with available baseline vital signs...
May 27, 2016: Journal of Trauma and Acute Care Surgery
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