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https://www.readbyqxmd.com/read/29334467/robot-assisted-upper-extremity-rehabilitation-for-cervical-spinal-cord-injuries-a-systematic-scoping-review
#1
Hardeep Singh, Janelle Unger, José Zariffa, Maureen Pakosh, Susan Jaglal, B Catharine Craven, Kristin E Musselman
Abstact Purpose: To provide an overview of the feasibility and outcomes of robotic-assisted upper extremity training for individuals with cervical spinal cord injury (SCI), and to identify gaps in current research and articulate future research directions. MATERIALS AND METHODS: A systematic search was conducted using Medline, Embase, PsycINFO, CCTR, CDSR, CINAHL and PubMed on June 7, 2017. Search terms included 3 themes: (1) robotics; (2) SCI; (3) upper extremity. Studies using robots for upper extremity rehabilitation among individuals with cervical SCI were included...
January 15, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29330514/a-comparison-of-static-and-dynamic-cerebral-autoregulation-during-mild-whole-body-cold-stress-in-individuals-with-and-without-cervical-spinal-cord-injury-a-pilot-study
#2
Jan W van der Scheer, Yoshi-Ichiro Kamijo, Christof A Leicht, Philip J Millar, Manabu Shibasaki, Victoria L Goosey-Tolfrey, Fumihiro Tajima
STUDY DESIGN: Experimental study. OBJECTIVES: To characterize static and dynamic cerebral autoregulation (CA) of individuals with cervical spinal cord injury (SCI) compared to able-bodied controls in response to moderate increases in mean arterial pressure (MAP) caused by mild whole-body cold stress. SETTING: Japan METHODS: Five men with complete autonomic cervical SCI (sustained > 5 y) and six age-matched able-bodied men participated in hemodynamic, temperature, catecholamine and respiratory measurements for 60 min during three consecutive stages: baseline (10 min; 33 °C water through a thin-tubed whole-body suit), mild cold stress (20 min; 25 °C water), and post-cold recovery (30 min; 33 °C water)...
January 12, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29328003/characterizing-the-type-and-location-of-intracranial-abnormalities-in-mild-traumatic-brain-injury
#3
Harri Isokuortti, Grant L Iverson, Noah D Silverberg, Anneli Kataja, Antti Brander, Juha Öhman, Teemu M Luoto
OBJECTIVE The incidence of intracranial abnormalities after mild traumatic brain injury (TBI) varies widely across studies. This study describes the characteristics of intracranial abnormalities (acute/preexisting) in a large representative sample of head-injured patients who underwent CT imaging in an emergency department. METHODS CT scans were systematically analyzed/coded in the TBI Common Data Elements framework. Logistic regression modeling was used to quantify risk factors for traumatic intracranial abnormalities in patients with mild TBIs...
January 12, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29327151/impact-of-admission-hypertension-on-rates-of-acute-kidney-injury-in-intracerebral-hemorrhage-treated-with-intensive-blood-pressure-control
#4
Hannah Hewgley, Stephen C Turner, Joseph E Vandigo, Jacob Marler, Heather Snyder, Jason J Chang, G Morgan Jones
BACKGROUND: Current guidelines recommend that rapid systolic blood pressure (SBP) lowering to 140 mmHg may be considered in intracerebral hemorrhage (ICH) patients regardless of initial SBP. However, limited safety data exist in patients presenting with varying degrees of severe hypertension. The purpose of this study was to determine whether there was an increased risk of acute kidney injury (AKI) based upon degree of presentation hypertension in ICH patients whose blood pressure was reduced intensively...
January 11, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29325839/the-effect-of-low-load-exercise-on-joint-pain-function-and-activities-of-daily-living-in-patients-with-knee-osteoarthritis
#5
Jason Peeler, Jacquie Ripat
BACKGROUND: Knee osteoarthritis has a lifetime risk of nearly one in two, with obese individuals being most susceptible. While exercise is universally recognized as a critical component for management, unsafe or ineffective exercise frequently leads to exacerbation of joint symptoms. AIM: Evaluate the effect of a 12week lower body positive pressure (LBPP) supported low-load treadmill walking program on knee pain, joint function, and performance of daily activities in patients with knee osteoarthritis (OA)...
January 8, 2018: Knee
https://www.readbyqxmd.com/read/29321231/chronic-traumatic-encephalopathy-in-an-epilepsy-surgery-cohort-clinical-and-pathologic-findings
#6
Amy L Jones, Jeffrey W Britton, Melissa M Blessing, Joseph E Parisi, Gregory D Cascino
OBJECTIVE: To determine the occurrence of chronic traumatic encephalopathy (CTE) in young adult patients undergoing epilepsy surgery. METHODS: Ten patients who underwent epilepsy surgery were randomly selected for this retrospective study. The patients were 18-45 years of age, had preoperative neuropsychological evaluation, and had 1 year postoperative follow-up. Microscopic sections from resections were evaluated for the presence of CTE with standard stains and antibodies to tau (clone AT8)...
January 10, 2018: Neurology
https://www.readbyqxmd.com/read/29319773/anca-positive-pauci-immune-crescentic-glomerulonephritis-in-a-patient-with-systemic-lupus-erythematosus
#7
Percy Herrera-Añazco, Percy Velásquez-Castillo, Josmel Pacheco-Mendoza, Germán Valenzuela-Rodriguez, Carmen Asato-Higa
The pauci-immune crescentic glomerulonephritis (PICGN) is generally associated with small-vessel vasculitis with a few reported cases associated with other autoimmune diseases such as Systemic Lupus Erythematosus (SLE). We present the case of a female 34-year-old patient with acute kidney injury symptoms with indication for renal replacement therapy in the context of clinical SLE diagnosis. A kidney biopsy was conducted and it was found that most glomeruli showed some segmental sclerosis with synechia to the Bowman's capsule...
October 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29318971/-phenserine-and-inhibiting-pre-programmed-cell-death-in-pursuit-of-a-novel-intervention-for-alzheimer-s-disease
#8
Robert E Becker, Nigel H Greig, Debomoy K Lahiri, Joseph Bledsoe, Sarah Majercik, Clive Ballard, Dag Aarsland, Lon S Schneiderh, Douglas Flanagan, Ramprakash Govindarajani, Mary Sano, Luigi Ferrucci, Dimitrios Kapogiannisk
BACKGROUND: Concussion (mild) and other moderate traumatic brain injury (TBI) and Alzheimer's disease (AD) share overlapping neuropathologies, including neuronal pre-programmed cell death (PPCD), and clinical impairments and disabilities. Multiple clinical trials targeting mechanisms based on the Amyloid Hypothesis of AD have so far failed, indicating that it is prudent for new drug developments to also pursue mechanisms independent of the Amyloid Hypothesis. To address these issue, we have proposed the use of an animal model of concussion/TBI as a supplement to AD transgenic mice to provide an indication of an AD drug candidate's potential for preventing PPCD and resulting progression towards dementia in AD...
January 10, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29316843/diagnosis-threat-and-underperformance-the-threat-must-be-relevant-and-implicit
#9
Megan Fresson, Benoit Dardenne, Thierry Meulemans
INTRODUCTION: The diagnosis threat (DT) phenomenon shows that, in some cases, reminding people with mild traumatic brain injury (mTBI) about their past neurological history diminishes subsequent cognitive performance. The aim of the present study was to investigate the role of personal relevance (i.e., domain identification) and type of threat (i.e., implicit vs. explicit) as moderating variables. We investigated intrusive thoughts as a potential mediator. METHOD: Control (non-mTBI) and mTBI participants were recruited and completed a domain identification questionnaire...
January 10, 2018: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/29316316/serum-but-not-exhaled-breath-condensate-periostin-level-is-increased-in-competitive-athletes
#10
Marcin Kurowski, Janusz Jurczyk, Marzanna Jarzębska, Aleksandra Wardzyńska, Hubert Krysztofiak, Marek L Kowalski
INTRODUCTION: Periostin is a matricellular protein expressed by many tissues. Its release may be enhanced, among others, through mechanical stimulation of muscles and bones as well as by cytokines of allergic inflammation. OBJECTIVES: Our aim was to assess periostin levels in serum and exhaled breath condensate (EBC) of professional athletes, asthmatics and healthy controls. We also sought to determine whether acute treadmill exercise influences serum and EBC periostin...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29308757/-correlation-study-between-entropy-index-and-glasgow-coma-scale-score-in-patients-with-acute-brain-injury
#11
Min Lu, Jing Zhang
OBJECTIVE: To investigate the correlation between the entropy index and Glasgow coma scale (GCS) score in patients with acute brain injury (ABI), and to explore the feasibility of using entropy index to assess the extent of brain damage. METHODS: A prospective study was conducted. 101 patients with ABI admitted to intensive care unit (ICU) of the First People's Hospital of Changshou from May 2015 to May 2017 were enrolled. The values of reaction entropy (RE) and state entropy (SE) within 24 hours after ICU admission were collected, and the GCS score was recorded...
January 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29302018/injuries-and-envenomation-by-exotic-pets-in-hong-kong
#12
V Ch Ng, A Ch Lit, O F Wong, M L Tse, H T Fung
INTRODUCTION: Exotic pets are increasingly popular in Hong Kong and include fish, amphibians, reptiles, and arthropods. Some of these exotic animals are venomous and may cause injuries and envenomation to their owners. The clinical experience of emergency physicians in the management of injuries and envenomation by these exotic animals is limited. We reviewed the clinical features and outcomes of injuries and envenomation by exotic pets recorded by the Hong Kong Poison Information Centre...
January 5, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29300291/incontinence-associated-dermatitis-characteristics-and-relationship-to-pressure-injury-a-multisite-epidemiologic-analysis
#13
Mikel Gray, Karen K Giuliano
PURPOSE: The purpose of this study was to measure the prevalence of incontinence-associated dermatitis (IAD) among incontinent persons in the acute care setting, characteristics of IAD in this group, and associations among IAD, urinary, fecal, and dual incontinence, immobility, and pressure injury in the sacral area. DESIGN: Descriptive and correlational analysis of data from a large database of IAD, and pressure injuries of sacral area and heels. SUBJECTS AND SETTING: The sample comprised 5342 adult patients in acute care facilities in 36 states representing all regions of the United States...
January 2018: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/29299652/hyaluronic-acid-injections-for-osteoarthritis-of-the-knee-predictors-of-successful-treatment
#14
Eric N Bowman, Justin D Hallock, Thomas W Throckmorton, Fredrick M Azar
PURPOSE: This study aimed to identify patient and treatment factors that predict a favourable response to intra-articular hyaluronic acid (HA) treatment to better guide patient and treatment selection. METHODS: This prospective, observational study evaluated patients with mild-to-moderate (Kellgren-Lawrence grades 1-3) primary knee osteoarthritis treated between March 2013 and May 2016. Patient function and pain scores were assessed by the Western Ontario and McMaster Universities Arthritis Index/Knee Injury and Osteoarthritis Outcome Score (WOMAC/KOOS) and visual analogue scale (VAS) surveys, with response to treatment defined according to the Osteoarthritis Research Society International (OARSI) 2004 criteria...
January 3, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29285344/a-model-for-the-optimization-of-anti-inflammatory-treatment-with-chemerin
#15
Simao Laranjeira, Daniel Regan-Komito, Asif J Iqbal, David R Greaves, Stephen J Payne, Piotr Orlowski
Routine treatment of mild to moderate pain with a combination of non-steroidal anti-inflammatory drugs such as paracetamol in combination with corticoid opioids can lead to severe complications including death from gastrointestinal injury or to drug dependence. There is a need for the development of new safer drugs. Chemerin is a mediator promoting resolution of inflammation and it is then a promising candidate for a new treatment. A pilot experimental work using the zymosan-induced peritonitis model has found that injecting extra chemerin resulted in an approximately 1% reduction in the total number of inflammatory cells recruited...
February 6, 2018: Interface Focus
https://www.readbyqxmd.com/read/29283961/injuries-associated-with-police-use-of-force
#16
William P Bozeman, Jason P Stopyra, David A Klinger, Brian P Martin, Derrel D Graham, James C Johnson, Katherine Mahoney-Tesoriero, Sydney J Vail
BACKGROUND: Use of Force [UOF] by police can result in serious injuries and fatalities. The risk of significant injuries associated with different force modalities is poorly defined. We sought to determine the incidence of police UOF and compare the likelihood of significant injury with different force modalities. METHODS: A prospective multicenter observational study of all UOF incidents was conducted via mandatory UOF investigations at three mid-sized police agencies over a two year period...
December 28, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29283307/using-the-california-verbal-learning-test-second-edition-as-an-embedded-performance-validity-measure-among-individuals-with-tbi-and-individuals-with-psychiatric-disorders
#17
Virginia C Persinger, Douglas M Whiteside, Lyuba Bobova, Seema D Saigal, Marla J Vannucci, Michael R Basso
OBJECTIVE: Among embedded performance validity tests (PVTs), little research addresses the use of Total Hits and Total False Positives from the California Verbal Learning Test, Second Edition (CVLT-II) in spite of low sensitivity, particularly in psychiatric samples. METHOD: This study examined the classification accuracy of these two measures in individuals with psychiatric disorders or mild traumatic brain injury (MTBI). These samples were separated into two groups using the criteria of passing all PVTs versus failing 2 or more PVTs...
December 28, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29282094/nasal-high-flow-therapy-in-very-low-birth-weight-infants-with-mild-respiratory-distress-syndrome-a-single-center-experience
#18
Antonio Di Mauro, Manuela Capozza, Sergio Cotugno, Silvio Tafuri, Francesco Paolo Bianchi, Federico Schettini, Raffaella Panza, Nicola Laforgia
BACKGROUND: Pulmonary disorders and respiratory failure represent one of the most common morbidities of preterm newborns admitted to neonatal intensive care units (NICUs). The use of nasal high-flow therapy (nHFT) has been more recently introduced into the NICUs as a non-invasive respiratory (NIV) support. METHODS: We performed a retrospective study to evaluate safety and effectiveness of nHFT as primary support for infants born < 29 weeks of gestation and/or VLBW presenting with mild Respiratory Distress Syndrome (RDS)...
December 28, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29280684/sport-related-concussive-convulsions-a-systematic-review
#19
Nicholas O Kuhl, Aaron M Yengo-Kahn, Hannah Burnette, Gary S Solomon, Scott L Zuckerman
OBJECTIVES: The incidence of sport-related concussion (SRC) continues to rise. Presentations of concussed athletes vary from subtle symptoms to notable signs. Between the 4th and 5th iterations of the Concussion in Sport Group (CISG) guidelines, concussive convulsions were removed as a modifying factor, but little evidence or discussion supported this change. While considerable research exists regarding post-traumatic epilepsy in moderate to severe traumatic brain injury, convulsions following SRC are relatively understudied...
December 27, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/29276644/hepatic-progenitor-cell-activation-in-liver-repair
#20
Adam Bria, Jorgessen Marda, Junmei Zhou, Xiaowei Sun, Qi Cao, Bryon E Petersen, Liya Pi
The liver possesses an extraordinary ability to regenerate after injury. Hepatocyte-driven liver regeneration is the default pathway in response to mild-to-moderate acute liver damage. When replication of mature hepatocytes is blocked, facultative hepatic progenitor cells (HPCs), also referred to as oval cells (OCs) in rodents, are activated. HPC/OCs have the ability to proliferate clonogenically and differentiate into several lineages including hepatocytes and bile ductal epithelia. This is a conserved liver injury response that has been studied in many species ranging from mammals (rat, mouse, and human) to fish...
September 2017: Liver Research
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