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Jiani Wu, Yanjun Cheng, Zongshi Qin, Xiaoxu Liu, Zhishun Liu
OBJECTIVE: To preliminarily explore the effect of electroacupuncture (EA) on bladder and bowel dysfunction in patients with transverse myelitis. METHODS: Sixteen participants were treated with EA at bilateral BL32, BL33, and BL35 once a day, five times a week for the first 4 weeks, and once every other day, three times a week for the following 4 weeks. Patients were then followed up for 6 months. Bladder and bowel function, and the safety of EA, were assessed...
June 16, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
J D Z Chen, M Ni, J Yin
Functional gastrointestinal (GI) diseases are common and there are patients who are refractory to medical therapies as not all treatments work in all patients. Consequently, a large number of patients with functional GI diseases use complementary and alternative medicine, such as acupuncture or electroacupuncture (EA). In this issue, Zheng et al. reported interesting results of a multi-center placebo-controlled clinical study on the use of EA for treating refractory functional dyspepsia; another study reported a multi-center clinical trial on EA for chronic functional constipation; Liang et al...
July 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
Yong Pang, Huimei Liu, Gaoxiong Duan, Hai Liao, Yanfei Liu, Zhuo Feng, Jien Tao, Zhuocheng Zou, Guoxiang Du, Rongchao Wan, Peng Liu, Demao Deng
Background : Premenstrual syndrome (PMS) is a menstrual cycle-related disorder which causes physical and mood changes prior to menstruation and is associated with the functional dysregulation of the brain. Acupuncture is an effective alternative therapy for treating PMS, and sanyinjiao (SP6) is one of the most common acupoints used for improving the symptoms of PMS. However, the mechanism behind acupuncture's efficacy for relieving PMS symptoms remains unclear. The aim of this study was to identify the brain response patterns induced by acupuncture at acupoint SP6 in patients with PMS...
2018: Frontiers in Human Neuroscience
Jiangsong Zhang, Xianming Lin, Hui Zhou, Yuanyuan Chen, Shuangkai Xiao, Junyue Jiao, Yibin Zhao, Zhong Di
OBJECTIVE: To examine for an opening effect on the blood-brain barrier (BBB) in intact rats and rats with experimental ischaemia-reperfusion (I/R) during the recovery period after various electroacupuncture (EA) treatments with different time courses, and to determine whether there is a time-dependent effect. An additional objective was to determine whether this method could induce the penetration of nerve growth factor (NGF) through the BBB. METHODS: A middle cerebral artery occlusion (MCAO) model was first established...
June 14, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
Yi-Wen Lin, Lih-Chiann Wang
  An 18-yr-old, captive-born male Bengal tiger ( Panthera tigris tigris) presented a 1-yr history of chronic and progressive paraparesis in both hind limbs. Lateral and hind limb radiographs were revealed normal except for severe spondylosis deformans, forming a bony bridge between the last lumbar and the first sacral vertebra and disc mineralization between the second and third lumbar vertebra. Medical therapies were instituted, including corticosteroids, hydroacupuncture and electroacupuncture. Animal training allowed veterinarians to perform acupuncture safely without having to anesthetize the animal...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Zhen Zheng, Stephen Gibson, Robert D Helme, Yanyi Wang, David Shao-Chen Lu, Carolyn Arnold, Malcolm Hogg, Andrew A Somogyi, Cliff Da Costa, Charlie Chang Li Xue
Objectives: To evaluate the efficacy and safety of electroacupuncture in reducing opioid consumption in patients with chronic musculoskeletal pain. Design: A randomized, participant-assessor-blinded, three-arm trial. Setting: Participants from three pain clinics and from the public. Subjects: One hundred and eight adults with chronic pain who were taking opioids. Methods: All participants received pain and medication management education...
June 8, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Chen-Yi Li, Si-Yi Yu, Bao-Jun Guo, Wen-Yao Li, Jiao Yang, You-Ping Hu
OBJECTIVE: To analyze studies published in journals included in PubMed in terms of randomized controlled trials (RCTs) examining the therapeutic effect of acupuncture for simple obesity, so as to provide a reference for subsequent RCT-related designs and results. METHODS: RCT literature about acupuncture treatment of simple obesity from the PubMed database and from 2000 to 2016 was retrieved by using keywords of "obesity" "fat" "acupuncture" "joint application of acupuncture and herbal medicine" or "auricular point" "electroacupuncture", "acupoint application", or "cupping", followed by screening, extraction and evaluation of the design methodology and outcomes using Consolidated Standards for Reporting of Trials (CONSORT) and Standards for Reporting Interventions in Controlled Trials of Acupuncture (STRICTA)...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Yi-Yu Peng, Hui-Tao Jing, Lan Luan, Ying-Ying Tu
OBJECTIVE: To observe the clinical efficacy of joint application of electroacupuncture (EA), acupointinjection and fire-needle in the treatment of menopausal syndrome (MS) women. METHODS: One hundred MS patients were randomized into control group and combined treatment group ( n =50 patients in each). The combined treatment group was treated by joint application of EA, acupoint-injection and fire-needle stimulation, and the control group treated by EA stimulation alone...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Ze-Dong Cheng, Wei Zhang
OBJECTIVE: To observe the effect of electroacupuncture (EA) on the expression of scavenger receptor A I (SR-A I) protein and mRNA in peritoneal macrophages of atherosclerosis (AS) rabbits. METHODS: A total of 26 New Zealand rabbits were used in the present study, among them, 7 were randomly selected to constitute a blank control group, and the rest 19 rabbits were fed with high-fat diet combined with carotid artery balloon injury for establishing AS model. Eight weeks after high-fat forage feeding, one high-fat fed rabbit and one normal rabbit were randomly selected for verifying the success of modeling...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Juan Tong, Fu-Chu Chen, Gui-Yuan Li, Xiang-Ao Kong, Ying He, Hong Yao
OBJECTIVE: To observe the immunoregulatory effect of electroacupuncture (EA) intervention for muscular dystrophy chronic obstructive pulmonary disease (COPD) rats, so as to investigate its underlying mechanism in improving respiratory function. METHODS: Forty male SD rats were randomly divided into 5 groups: normal, model, EA, exercise, and EA+ exercise ( n =8 in each). The muscular dystrophy COPD model was established by placing the rats in a closed box to be exposed to cigarette smoke (3-10 cigarettes/time) for 60 min, twice daily, 6 days a week for 90 days...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Nai-Gang Liu, Jia-Ni Yu, Bo Hu, Yan Guo, Chang-Qing Guo
OBJECTIVE: We have demonstrated that needle knife (acupotomy) treatment can improve knee osteoarthritis (KOA) in rabbits. The present study was designed to examine its effect on expression of phosphorylated focal adhesion kinase (p-FAK), phosphinositides 3 kinase (p-PI 3 K) and Aggrecan genes and proteins in the knee-joint cartilage tissues of KOA rabbits, so as to explore its partial molecular mechanism underlying improvement of KOA. METHODS: Forty-nine New Zealand male rabbits were randomly divided into normal control, model, model +inhibitor, needle knife, needle knife+ inhibitor, electroacupuncture (EA), EA +inhibitor groups ( n =7 in each)...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Qing-Hua Yang, Ling Guo, Qing Chen, Kai-Hui Wu, Yan-Jun Wu, Yan Jia, Shu-Juan Zhu, Cheng-Lin Tang, Hua-Jun Sheng
OBJECTIVE: To observe the effect of electroacupuncture (EA) intervention on learning-memory ability and the expression of senile plaques (SP), amyloid precursor protein (APP), β-secretase 1(BACE 1) and insulin degrading enzyme (IDE) in the hippocampus in APP/presenilin 1 (PS 1) double transgenic Alzheimer's disease (AD) mice, so as to reveal its mechanisms underlying improvement of AD. METHODS: A total of 18 male APP/PS 1 double transgenic AD mice were randomly divided into model, EA-2-week and EA-3-week groups ( n =6 in each)...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Cai-Hua Wu, Hong-Rong Mao, Hong-Ping Li, Xiao-Cui Yuan, Hong-Chun Xiang, He Zhu, Man Li
OBJECTIVE: To observe the effect of different frequencies of electroacupuncture (EA) stimulation on pain threshold (PT) and expression of vascular endothelial growth factor (VEGF) in dorsal horns (DHs) of the lumbar spinal cord in resiniferatoxin (RTX)-induced post-herpetic neuralgia (PHN) rats, so as to reveal its mechanism in alleviating PHN. METHODS: Male SD rats were randomized into control, model, 2 Hz-EA, 15 Hz-EA, 100 Hz-EA and sham EA groups ( n =16 in each)...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Min-Hui Li, Hao Hong, Sheng-Feng Lu, Jun-Meng Wang, Bing-Mei Zhu
OBJECTIVE: To observe the effect of electroacupuncture (EA) on insulin signaling pathway in liver tissues of central neuronal specific signal transduction and activator of transcription 5 conditional-knockout ( Stat 5 NKO) mice, so as to explore its mechanism underlying improvement of insulin resistance (IR).. METHODS: Twenty-four male Stat 5 NKO mice were randomly divided into model and EA groups ( n =12 mice/group), and 12 Stat 5 fl/fl mice were used as the normal control group...
May 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Yi Zhu, Yi Li, Nan Zhang, Gui-Rong Dong
OBJECTIVE: To observe the effect of electroacupuncture (EA) preconditioning on acute myocardial ischemia (MI) and expression of Toll-like receptor 4 (TLR 4), myeloid differentiation factor 88 (MyD 88) and nuclear factor-κB (NF-κB) mRNAs in the "Neiguan" (PC 6) area of rats with MI-reperfusion injury (MIRI), so as to explore its mechanisms underlying improvement of MIRI. METHODS: Forty-eight male Wistar rats were randomly divided into control, control + EA, sham operation, model, EA and sham EA groups ( n =8)...
May 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Yao-Guo Han, Xiong Qin, Tao Zhang, Ming Lei, Fang-Yuan Sun, Jing-Jing Sun, Wei-Fang Yuan
Oxidative stress and neuroinflammation play an important role in the pathophysiology of lipopolysaccharide (LPS)-induced cognitive impairment. This study aims to observe the effect of electroacupuncture (EA) on the cognitive function in LPS-induced mice, and its regulation on hippocampal α7 nicotinic acetylcholine receptors (α7nAChR), oxidative and proinflammatory factors. Adult male C57BL/6 nice were used to establish animal model of LPS-induced cognitive impairment, and were randomly divided into three groups (n = 16): control group, model group (LPS: 5 mg/kg), and EA group...
June 6, 2018: Neuroscience Letters
Yi-Fan Li, Tie Li, Da-Wei Zhang, Hui Xue, Dong Chen, Chen Li, Fu-Chun Wang
The present study aimed to evaluate the role of the combination treatment of methylprednisolone (MP) and electroacupuncture (EA) in regeneration of nerve fibers and functional recovery in rats with spinal cord injury (SCI). Female Wistar rats were used for an SCI model by using a weight-drop hammer at levels T10 (spinal cord segment corresponding to the 10th thoracic vertebra). Four groups received different treatments for the study: SCI control, MP, MP and EA, and Sham. The growth of nerve fibers was examined by counting fluorescein positive nerve fibers...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Dong Lin, Jie Zhang, Wanyu Zhuang, Xiaodan Yan, Xiaoting Yang, Shen Lin, Lili Lin
Our previous study showed that the acupuncture stimulation on the acupoint (ST-36) could activate the brain-derived neurotropic factor (BDNF) signaling pathways in telomerase-deficient mice. Recently, we set out to investigate whether the manual acupuncture (MA) or electroacupuncture (EA) displays a therapeutic advantage on age-related deterioration of learning and memory. Both telomerase-deficient mice (Terc-/- group, n = 24) and wild-type mice (WT group, n = 24) were randomly assigned to 3 subgroups (CON, controls with no treatment; MA, mice receiving manual acupuncture; EA, mice receiving electric acupuncture)...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Ji-Yeun Park, Uk Namgung
Although acupuncture therapy is increasingly used to treat diverse symptoms and disorders in humans, its underlying mechanism is not known well. Only recently have experimental studies begun to provide insights into how acupuncture stimulation generates and relates to pathophysiological responsiveness. Acupuncture intervention is frequently used to control pathologic symptoms in several visceral organs, and a growing number of studies using experimental animal models suggest that acupuncture stimulation may be involved in inducing anti-inflammatory responses...
2018: Journal of Inflammation Research
Huan Wang, Zhen Liu, Yuanshi Liu, Zhanqi Tong, Yan Qian, Liping Chen, Bin Jiang, Mingxiong Lin, Tao Yang, Lu Gao, Mingjun Chen, Daniela Litscher, Lu Wang, Gerhard Litscher
Fluid resuscitation could hardly be performed immediately after fatal hemorrhagic shock in outpatients. We investigated whether electroacupuncture (EA) at Zusanli (ST36) could prevent fatal hemorrhagic shock induced heart failure with delayed fluid resuscitation and whether the protective role of EA is related to the autonomic nervous system. Sixty Sprague Dawley rats were randomly divided into five groups ( n = 12 each): group of sham hemorrhagic shock (SHAM), group of EA, group of sham EA (SEA), group of delayed fluid resuscitation with EA (EA + DR), and group of delayed fluid resuscitation with SEA (SEA + DR)...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
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