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https://www.readbyqxmd.com/read/29670665/research-on-biomimetic-models-and-nanomechanical-behaviour-of-membranous-wings-of-chinese-bee-apis-cerana-cerana-fabricius
#1
Yanru Zhao, Dongsheng Wang, Jin Tong, Jiyu Sun, Jin Zhang
The structures combining the veins and membranes of membranous wings of the Chinese bee Apis cerana cerana Fabricius into a whole have excellent load-resisting capacity. The membranous wings of Chinese bees were taken as research objects and the mechanical properties of a biomimetic model of membranous wings as targets. In order to understand and learn from the biosystem and then make technical innovation, the membranous wings of Chinese bees were simulated and analysed with reverse engineering and finite element method...
2018: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29643828/lateralization-of-sucrose-responsiveness-and-non-associative-learning-in-honeybees
#2
David Baracchi, Elisa Rigosi, Gabriela de Brito Sanchez, Martin Giurfa
Lateralization is a fundamental property of the human brain that affects perceptual, motor, and cognitive processes. It is now acknowledged that left-right laterality is widespread across vertebrates and even some invertebrates such as fruit flies and bees. Honeybees, which learn to associate an odorant (the conditioned stimulus, CS) with sucrose solution (the unconditioned stimulus, US), recall this association better when trained using their right antenna than they do when using their left antenna. Correspondingly, olfactory sensilla are more abundant on the right antenna and odor encoding by projection neurons of the right antennal lobe results in better odor differentiation than those of the left one...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29643175/impaired-associative-learning-after-chronic-exposure-to-pesticides-in-young-adult-honey-bees
#3
Carolina Mengoni Goñalons, Walter M Farina
Neonicotinoids are the most widespread insecticides in agriculture, preferred for their low toxicity to mammals and their systemic nature. Nevertheless, there have been increasing concerns regarding their impact on non-target organisms. Glyphosate is also widely used in crops and, therefore, traces of this pesticide are likely to be found together with neonicotinoids. Although glyphosate is considered a herbicide, adverse effects have been found on animal species, including honey bees. Apis mellifera is one of the most important pollinators in agroecosystems and is exposed to both these pesticides...
April 11, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29613851/an-innovative-solution-to-detect-classify-and-report-illicit-online-marketing-and-sales-of-controlled-substances-via-twitter-project-finalist-at-hhs-opioid-code-a-thon
#4
Tim Mackey, Janani Kalyanam, Josh Klugman, Ella Kuzmenko, Rashmi Gupta
BACKGROUND: On December 6-7, 2017, the U.S. Department of Health and Human Services hosted its first Code-a-Thon event aimed at leveraging technology and data-driven solutions to help combat the opioid epidemic. Authors, comprised of an interdisciplinary team from academia, the private sector, and the U.S. Centers for Disease Control and Prevention, participated in the Code-a-Thon as part of the "Prevention" track. OBJECTIVE: To develop and deploy a methodology using machine learning to accurately detect the marketing and sale of opioids by illicit online sellers via Twitter as part of participation at the HHS Opioid Code-a-Thon event...
March 27, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29559549/visual-discrimination-transfer-and-modulation-by-biogenic-amines-in-honeybees
#5
Amanda Rodrigues Vieira, Nayara Salles, Marco Borges, Theo Mota
For more than a century, visual learning and memory has been studied in the honeybee Apis mellifera using operant appetitive conditioning. Although honeybees show impressive visual learning capacities in this well-established protocol, operant training of free-flying animals can hardly be combined with invasive protocols for studying the neurobiological basis of visual learning. In view of that, different efforts have been made to develop new classical conditioning protocols for studying visual learning in harnessed honeybees, though learning performances remain considerably poorer than those obtained in free-flying animals...
March 20, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29556758/pybiomed-a-python-library-for-various-molecular-representations-of-chemicals-proteins-and-dnas-and-their-interactions
#6
Jie Dong, Zhi-Jiang Yao, Lin Zhang, Feijun Luo, Qinlu Lin, Ai-Ping Lu, Alex F Chen, Dong-Sheng Cao
BACKGROUND: With the increasing development of biotechnology and informatics technology, publicly available data in chemistry and biology are undergoing explosive growth. Such wealthy information in these data needs to be extracted and transformed to useful knowledge by various data mining methods. Considering the amazing rate at which data are accumulated in chemistry and biology fields, new tools that process and interpret large and complex interaction data are increasingly important...
March 20, 2018: Journal of Cheminformatics
https://www.readbyqxmd.com/read/29536541/foxp-in-bees-a-comparative-study-on-the-developmental-and-adult-expression-pattern-in-three-bee-species-considering-isoforms-and-circuitry
#7
Adriana Schatton, Ezequiel Mendoza, Kathrin Grube, Constance Scharff
Mutations in the transcription factors FOXP1, FOXP2 and FOXP4 affect human cognition, including language. The FoxP gene locus is evolutionarily ancient and highly conserved in its DNA-binding domain. In Drosophila melanogaster FoxP has been implicated in courtship behavior, decision making and specific types of motor-learning. Because honeybees (Apis mellifera, Am) excel at navigation and symbolic dance communication, they are a particularly suitable insect species to investigate a potential link between neural FoxP expression and cognition...
March 14, 2018: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29529024/lailaps-qsm-a-restful-api-and-java-library-for-semantic-query-suggestions
#8
Jinbo Chen, Uwe Scholz, Ruonan Zhou, Matthias Lange
In order to access and filter content of life-science databases, full text search is a widely applied query interface. But its high flexibility and intuitiveness is paid for with potentially imprecise and incomplete query results. To reduce this drawback, query assistance systems suggest those combinations of keywords with the highest potential to match most of the relevant data records. Widespread approaches are syntactic query corrections that avoid misspelling and support expansion of words by suffixes and prefixes...
March 12, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29428908/molecular-cloning-and-expression-analysis-of-the-tyramine-br-receptor-genes-in-apis-cerana-cerana
#9
Li-Zhen Zhang, Yong Zhang, Jing-Hua Hu, Zi-Long Wang, Zhi-Jiang Zeng
Tyramine is a biological polyamine, which serves important functions as neurotransmitters, neuromodulators and neurohormone of the central nervous system. It participates in the regulation of various behavior and physiological processes in insects. For example, tyramine and its receptor genes are involved in the regulation of learning and memory in the animals. In this study, the full-length cDNA sequences of the tyramine receptor genes (Actyr1 and Actyr2) of the Chinese honeybee, Apis cerana cerana, were cloned and sequenced for the first time...
February 20, 2018: Yi Chuan, Hereditas
https://www.readbyqxmd.com/read/29423537/short-term-exposure-to-lambda-cyhalothrin-negatively-affects-the-survival-and-memory-related-characteristics-of-worker-bees-apis-mellifera
#10
Chun-Hua Liao, Xu-Jiang He, Zi-Long Wang, Andrew B Barron, Bo Zhang, Zhi-Jiang Zeng, Xiao-Bo Wu
Pesticides are considered one of the major contemporary stressors of honey bee health. In this study, the effects of short-term exposure to lambda-cyhalothrin on lifespan, learning, and memory-related characteristics of Apis mellifera were systematically examined. Short-term exposure to lambda-cyhalothrin in worker bees reduced lifespan, affected learning and memory performance, reduced the homing ability, and influenced the expression levels of two learning and memory-related genes of A. mellifera. This research identifies the nature of the sublethal effects of lambda-cyhalothrin on bees and the level of exposure that can be harmful to bee health...
February 8, 2018: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29405233/the-value-of-pre-screening-in-the-alzheimer-s-prevention-initiative-api-autosomal-dominant-alzheimer-s-disease-trial
#11
S Rios-Romenets, M Giraldo-Chica, H López, F Piedrahita, C Ramos, N Acosta-Baena, C Muñoz, P Ospina, C Tobón, W Cho, M Ward, J B Langbaum, P N Tariot, E M Reiman, F Lopera
The Alzheimer's Prevention Initiative (API) Autosomal Dominant Alzheimer's Disease (ADAD) trial evaluates the anti-amyloid-β antibody crenezumab in cognitively unimpaired persons who, based on genetic background and age, are at high imminent risk of clinical progression, and provides a powerful test of the amyloid hypothesis. The Neurosciences Group of Antioquia implemented a pre-screening process with the goals of decreasing screen failures and identifying participants most likely to adhere to trial requirements of the API ADAD trial in cognitively unimpaired members of Presenilin1 E280A mutation kindreds...
2018: Journal of Prevention of Alzheimer's Disease
https://www.readbyqxmd.com/read/29361585/the-reluctant-visitor-an-alkaloid-in-toxic-nectar-can-reduce-olfactory-learning-and-memory-in-asian-honey-bees
#12
Junjun Zhang, Zhengwei Wang, Ping Wen, Yufeng Qu, Ken Tan, James C Nieh
The nectar of the thunder god vine, Tripterygium hypoglaucum , contains a terpenoid, triptolide (TRP), that may be toxic to the sympatric Asian honey bee, Apis cerana , because honey produced from this nectar is toxic to bees. However, these bees will forage on, recruit for, and pollinate this plant during a seasonal dearth of preferred food sources. Olfactory learning plays a key role in forager constancy and pollination, and we therefore tested the effects of acute and chronic TRP feeding on forager olfactory learning, using proboscis extension reflex conditioning...
March 1, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29361577/-nosema-ceranae-parasitism-impacts-olfactory-learning-and-memory-and-neurochemistry-in-honey-bees-apis-mellifera
#13
Stephanie L Gage, Catherine Kramer, Samantha Calle, Mark Carroll, Michael Heien, Gloria DeGrandi-Hoffman
Nosema sp. is an internal parasite of the honey bee, Apis mellifera , and one of the leading contributors to colony losses worldwide. This parasite is found in the honey bee midgut and has profound consequences for the host's physiology. Nosema sp. impairs foraging performance in honey bees, yet, it is unclear whether this parasite affects the bee's neurobiology. In this study, we examined whether Nosema sp. affects odor learning and memory and whether the brains of parasitized bees show differences in amino acids and biogenic amines...
February 19, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29330349/pharmacologic-inhibition-of-phospholipase-c-in-the-brain-attenuates-early-memory-formation-in-the-honeybee-apis-mellifera-l
#14
Shota Suenami, Shiori Iino, Takeo Kubo
Although the molecular mechanisms involved in learning and memory in insects have been studied intensively, the intracellular signaling mechanisms involved in early memory formation are not fully understood. We previously demonstrated that phospholipase C epsilon ( PLCe ), whose product is involved in calcium signaling, is almost selectively expressed in the mushroom bodies, a brain structure important for learning and memory in the honeybee. Here, we pharmacologically examined the role of phospholipase C (PLC) in learning and memory in the honeybee...
January 12, 2018: Biology Open
https://www.readbyqxmd.com/read/29259229/the-pesticide-flupyradifurone-impairs-olfactory-learning-in-asian-honey-bees-apis-cerana-exposed-as-larvae-or-as-adults
#15
Ken Tan, Cao Wang, Shihao Dong, Xinyu Li, James C Nieh
Relatively little attention has focused on how pesticides may affect Asian honey bees, which provide vital crop pollination services and are key native pollinators. We therefore studied the effects of a relatively new pesticide, flupyradifurone (FLU), which has been developed, in part, because it appears safer for honey bees than neonicotinoids. We tested the effects of FLU on Apis cerana olfactory learning in larvae (lower dose of 0.033 µg/larvae/day over 6 days) and, in a separate experiment, adults (lower dose of 0...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29208987/genome-wide-dna-methylation-changes-associated-with-olfactory-learning-and-memory-in-apis-mellifera
#16
You Li, Li-Zhen Zhang, Yao Yi, Wan-Wan Hu, Ya-Hui Guo, Zhi-Jiang Zeng, Zachary-Y Huang, Zi-Long Wang
The honeybee is a model organism for studying learning and memory formation and its underlying molecular mechanisms. While DNA methylation is well studied in caste differentiation, its role in learning and memory is not clear in honeybees. Here, we analyzed genome-wide DNA methylation changes during olfactory learning and memory process in A. mellifera using whole genome bisulfite sequencing (WGBS) method. A total of 853 significantly differentially methylated regions (DMRs) and 963 differentially methylated genes (DMGs) were identified...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29208222/using-virtual-reality-to-study-visual-performances-of-honeybees
#17
REVIEW
Patrick Schultheiss, Alexis Buatois, Aurore Avarguès-Weber, Martin Giurfa
Virtual reality (VR) offers an appealing experimental framework for studying visual performances of insects under highly controlled conditions. In the case of the honeybee Apis mellifera, this possibility may fill the gap between behavioural analyses in free-flight and cellular analyses in the laboratory. Using automated, computer-controlled systems, it is possible to generate virtual stimuli or even entire environments that can be modified to test hypotheses on bee visual behaviour. The bee itself can remain tethered in place, making it possible to record neural activity while the bees is performing behavioural tasks...
December 2017: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/29187519/proteomics-reveals-the-molecular-underpinnings-of-stronger-learning-and-memory-in-eastern-compared-to-western-bees
#18
Lifeng Meng, Xinmei Huo, Mao Feng, Yu Fang, Bin Han, Han Hu, Fan Wu, Jianke Li
The eastern ( Apis cerana cerana, Acc) and western ( Apis mellifera ligustica, Aml) honeybee are two major honeybee species. Surprisingly, little is known about the fundamental molecular neurobiology of brain suborgans of Acc and Aml. We characterized and compared the proteomes of mushroom bodies (MBs), antennal lobes (ALs) and optical lobes (OLs) in the brain of both species, and biologically validated the functions related to learning and memory. Acc and Aml have evolved similar proteome signatures in MBs and OLs to drive the domain-specific neural activities...
February 2018: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/29161513/insights-into-the-molecular-basis-of-the-acute-contact-toxicity-of-diverse-organic-chemicals-in-the-honey-bee
#19
Xiao Li, Yuan Zhang, Hongna Chen, Huanhuan Li, Yong Zhao
Use of chemical pollutants, including pesticides and other industrial chemicals, has resulted in significant risks to the whole ecosystem. Therefore, ecological risk assessment of chemicals is vital and necessary. Since the honey bee (Apis mellifera) is probably among the most exposed species to the polluting chemicals, we focused on the in silico estimation of honey bee toxicity (HBT) of chemicals and the analysis of the relevance of chemical HBT and several key physical-chemical properties and structural characteristics...
December 26, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29127660/exposure-to-a-sublethal-concentration-of-imidacloprid-and-the-side-effects-on-target-and-nontarget-organs-of-apis-mellifera-hymenoptera-apidae
#20
Aline Fernanda Catae, Thaisa Cristina Roat, Marcel Pratavieira, Anally Ribeiro da Silva Menegasso, Mario Sergio Palma, Osmar Malaspina
The use of insecticides has become increasingly frequent, and studies indicate that these compounds are involved in the intoxication of bees. Imidacloprid is a widely used neonicotinoid; thus, we have highlighted the importance of assessing its oral toxicity to Africanized bees and used transmission electron microscopy to investigate the sublethal effects in the brain, the target organ, and the midgut, responsible for the digestion/absorption of food. In addition, the distribution of proteins involved in important biological processes in the brain were evaluated on the 1st day of exposure by MALDI-imaging analysis...
November 10, 2017: Ecotoxicology
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