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https://www.readbyqxmd.com/read/28530054/-traditional-chinese-medicine-in-treatment-of-atopic-dermatitis
#1
Orit Schachter, David Perla, Shoshana Greenberger, Aviv Barzilai, Sharon Baum
BACKGROUND: Atopic dermatitis is a common chronic inflammatory skin disease, affecting up to 15-30% of children in industrialized countries. As there is no definitive cure for atopic dermatitis, patients often seek other complementary therapeutic options, such as traditional Chinese medicine (TCM). TCM comprises numerous treatment modalities for the management of atopic dermatitis including acupuncture and herbal medicine. We report a case of a two and a half year old child with atopic dermatitis exacerbation treated successfully with TCM...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28529748/local-modulated-electro-hyperthermia-in-combination-with-traditional-chinese-medicine-vs-intraperitoneal-chemoinfusion-for-the-treatment-of-peritoneal-carcinomatosis-with-malignant-ascites-a-phase-ii-randomized-trial
#2
Clifford L K Pang, Xinting Zhang, Zhen Wang, Junwen Ou, Yimin Lu, Pengfei Chen, Changlin Zhao, Xiaopu Wang, Hongyu Zhang, Sergey V Roussakow
The purpose of this study was to develop a safe and non-toxic alternative to the conventional conservative treatment of peritoneal carcinomatosis with malignant ascites (PCMA) by investigating the efficacy and safety of local modulated electro-hyperthermia (mEHT) combined with the traditional Chinese medicine (TCM) 'Shi Pi' herbal decoction, compared with standard intraperitoneal chemoinfusion (IPCI). A randomized, controlled, single-center, open-label clinical trial (phase II) with two parallel groups (allocation ratio, 1:1) was conducted to investigate the efficacy and safety of mEHT+TCM (study group, SG) vs...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28529575/japanese-kampo-medicine-ninjin-yoeito-synergistically-enhances-tumor-vaccine-effects-mediated-by-cd8-t-cells
#3
Shun Takaku, Masumi Shimizu, Hidemi Takahashi
Although Japanese traditional herbal medicine (Kampo) has been widely applied to the treatment of various diseases, including cancer, their mechanisms of action have not yet been elucidated in detail, particularly regarding their role in tumor immunology. The present study investigated the antitumor effects of the Japanese Kampo medicine, ninjin'yoeito (NYT; Ren-Shen-Yang-Rong-Tang in Chinese), which was orally administered with or without an irradiated tumor cell vaccine to a subcutaneous CT26 colon carcinoma tumor model...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28527517/holistic-evaluation-of-san-huang-tablets-using-a-combination-of-multi-wavelength-quantitative-fingerprinting-and-radical-scavenging-assays
#4
Yan Wang, Guo-Xiang Sun, Yang Jin, Xiu-Man Xie, Ying-Chun Liu, Di-Di Ma, Jing Zhang, Jia-Yue Gao, Yan-Fei Li
The present study was designed to establish a multi-wavelength quantitative fingerprinting method for San-Huang Tablets (SHT), a widely used and commercially available herbal preparation, where high performance liquid chromatography (HPLC) with a diode array detector (DAD) was employed to obtain the fingerprint profiles. A simple linear quantitative fingerprint method (SLQFM) coupled with multi-ingredient simultaneous determination was developed to evaluate the quality consistency of the tested samples qualitatively and quantitatively...
April 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28524372/herbal-formula-baogan-yihao-bgyh-prevented-dimethylnitrosamine-dmn-induced-liver-injury-in-rats
#5
Xiujie Liu, Jing Su, Yu Shi, Ying Guo, Imran Suheryani, Shicong Zhao, Yulin Deng, Weiwei Meng, Yan Chen, Lili Sun, Rongji Dai
Preclinical Research Baogan Yihao (BGYH) is a traditional Chinese herbal medicine for the treatment of chronic liver diseases. In this study, the effects of BGYH on dimethylnitrosamine (DMN)-induced liver fibrosis were investigated using a rat model. BGYH alleviate liver damage, as indicated by decreased levels of AST, ALT, γ-GT, and AKP. BGYH also prevented collagen deposition and reduced pathological tissue injury in liver tissue. In fibrosis, high levels of α-SMA and TGF-β in liver tissue were markedly attenuated by BGYH...
May 19, 2017: Drug Development Research
https://www.readbyqxmd.com/read/28522917/effects-of-chinese-herbal-medicine-xiangbin-prescription-on-gastrointestinal-motility
#6
Zhi Jiang, Li-Xing Cao, Bo Liu, Qi-Cheng Chen, Wen-Fan Shang, Lu Zhou, Dan-Yan Li, De-An Guo, Zhi-Qiang Chen
AIM: To investigate the effects of Xiangbin prescription (XBP), a Chinese herbal concoction, on gastrointestinal motility. METHODS: Forty healthy volunteers were recruited for this randomized controlled trial of XBP. Antroduodenojejunal manometry was used to monitor gastrointestinal motility in these subjects. After the subjects had fasted for at least 12 h, XBP (n = 30) or placebo (n = 10) was orally administrated and gastrointestinal motility was recorded for 4 h...
April 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28521677/molluscum-contagiosum-an-update
#7
Alexander Kc Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Molluscum contagiosum is a viral cutaneous infection in childhood that occurs worldwide. Physicians should familiarize themselves with this common condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications and, in particular, treatment of molluscum contagiosum. METHODS: A PubMed search was completed in Clinical Queries using the key term "molluscum contagiosum". Patents were searched using the key term "molluscum contagiosum" from www...
May 17, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28512501/effect-of-traditional-chinese-medicine-product-qiangguyin-on-bone-mineral-density-and-bone-turnover-in-chinese-postmenopausal-osteoporosis
#8
Zhen-Yu Shi, Xin-Gen Zhang, Chun-Wen Li, Kang Liu, Bo-Cheng Liang, Xiao-Lin Shi
Introduction. The aim of this study was to investigate the efficacy of herbal formula QiangGuYin (QGY) in postmenopausal women. Materials and Methods. A total of 240 participants from six clinical centers were randomly to receive alendronate 70 mg/week, QGY granules 20 g/day, and placebo. Primary end points were BMD changes over 6 and 12 months; secondary end points were bone turnover markers changes at 3, 6, 9, and 12 months. Safety was monitored by clinical adverse events reported during the follow-up...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28507818/screening-of-a-natural-compound-library-identifies-emodin-a-natural-compound-from-rheum-palmatum-linn-that-inhibits-dpp4
#9
Zhaokai Wang, Longhe Yang, Hu Fan, Peng Wu, Fang Zhang, Chao Zhang, Wenjie Liu, Min Li
Historically, Chinese herbal medicines have been widely used in the treatment of hyperglycemia, but the mechanisms underlying their effectiveness remain largely unknown. Here, we screened a compound library primarily comprised of natural compounds extracted from herbs and marine organisms. The results showed that emodin, a natural compound from Rheum palmatum Linn, inhibited DPP4 activity with an in vitro IC50 of 5.76 µM without inhibiting either DPP8 or DPP9. A docking model revealed that emodin binds to DPP4 protein through Glu205 and Glu206, although with low affinity...
2017: PeerJ
https://www.readbyqxmd.com/read/28506228/chinese-herbal-pulian-ointment-in-treating-psoriasis-vulgaris-of-blood-heat-syndrome-a-multi-center-double-blind-randomized-placebo-controlled-trial
#10
Nuo Li, Wenbin Zhao, Jianmin Xing, Jianping Liu, Guangzhong Zhang, Yunbi Zhang, Yuanwen Li, Wali Liu, Fei Shi, Yanping Bai
BACKGROUND: Traditional Chinese medicine (TCM) has a long history in the treatment of psoriasis vulgaris. We aimed to evaluate the clinical efficacy and safety of Chinese herbal Pulian ointment in treating psoriasis vulgaris of blood-heat syndrome. METHODS: A multicenter, randomized, double-blind, placebo-controlled trial was conducted. Participants with psoriasis vulgaris of blood-heat syndrome were blinded and randomized to receive Pulian ointment or placebo ointment twice daily for 4 weeks, with follow-up 8 weeks after treatment...
May 15, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28504115/protocatechuic-acid-inhibits-hepatitis-b-virus-replication-by-activating-erk1-2-pathway-and-down-regulating-hnf4%C3%AE-and-hnf1%C3%AE-in-vitro
#11
Xiao-Qing Dai, Wen-Tao Cai, Xiao Wu, Yong Chen, Feng-Mei Han
AIMS: Protocatechuic acid (PCA) is a phenolic compound found in many antiviral Chinese herbal medicines. HNF4α and HNF1α, the members of hepatocyte nuclear factor (HNF) family, play an important regulatory role in the gene transcription of hepatitis B virus (HBV). Previous studies found that PCA inhibited HBV antigen secretion and HBV DNA replication in HepG2.2.15 cells, but its anti-HBV mechanism has not been fully understood. We aim to illustrate the anti-HBV mechanism of PCA. MATERIALS AND METHODS: MTT was used to estimate cytotoxicity...
May 12, 2017: Life Sciences
https://www.readbyqxmd.com/read/28499829/characteristics-of-traditional-chinese-medicine-usage-in-children-with-precocious-puberty-a-nationwide-population-based-study
#12
Yi-Chun Lin, Tung-Ti Chang, Husan-Ju Chen, Chung-Hsing Wang, Mao-Feng Sun, Hung-Rong Yen
ETHNOPHARMACOLOGICAL RELEVANCE: Precocious puberty (PP) occurs in children with the early onset of pubertal development leading to physical and psychological problems. Current medical treatment is expensive and has its side effects. However, little is known about the utilization of traditional Chinese medicine (TCM) among patients with PP. To characterize the application of TCM among these patients, we conducted a nationwide population-based study. MATERIALS AND METHODS: We used the Taiwanese National Health Insurance Research Database (NHIRD), to perform a nationwide population-based study...
May 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28496368/self-management-and-psychological-sexological-interventions-in-patients-with-endometriosis-strategies-outcomes-and-integration-into-clinical-care
#13
REVIEW
Laura Buggio, Giussy Barbara, Federica Facchin, Maria Pina Frattaruolo, Giorgio Aimi, Nicola Berlanda
Endometriosis has a multifactorial etiology. The onset and progression of the disease are believed to be related to different pathogenic mechanisms. Among them, the environment and lifestyle may play significant roles. Diet, dietary supplements, physical exercise, osteopathy, massage, acupuncture, transcutaneous electrical nerve stimulation, and Chinese herbal medicine may represent a complementary and feasible approach in the treatment of symptoms related to the disease. In this narrative review, we aimed to examine the most updated evidence on these alternative approaches implicated in the self-management of the disease...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28494854/yangfei-kongliu-formula-a-compound-chinese-herbal-medicine-combined-with-cisplatin-inhibits-growth-of-lung-cancer-cells-through-transforming-growth-factor-%C3%AE-1-signaling-pathway
#14
Shui-Jie Shen, Yong-Hong Zhang, Xiao-Xia Gu, Shui-Ju Jiang, Ling-Jun Xu
OBJECTIVE: To investigate the tumor inhibition effect of Yangfei Kongliu Formula (YKF), a compound Chinese herbal medicine, combined with cisplatin (DDP) and its action mechanisms. METHODS: C57BL/6 mice with Lewis lung carcinoma were divided into six groups: control group (C), DDP group (2 mg/kg, DDP), low-dose YKF group (2.43 g/kg, L), high-dose YKF group (24.3 g/kg, H), low-dose YKF combined with DDP group (L + DDP) and high-dose YKF combined with DDP group (H + DDP)...
May 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28493524/rapid-identification-and-global-characterization-of-multiple-constituents-from-the-essential-oil-of-cortex-dictamni-based-on-gc-ms
#15
Weiyu Zhai, Jianhua Liu, Qi Liu, Yumei Wang, Dezhu Yang
The root of Dictamnus dasycarpus Turcz., also known as Cortex Dictamni, is a Chinese herbal medicine commonly used in the treatment of inflammation, microbial infection, cancer and other diseases in China for thousands of years. Recently, the essential oil of Cortex Dictamni has been widely studied and a large number of volatile constituents have been discovered. However, the research of the essential oil of Cortex Dictamni in vivo remains unknown, especially the constituents absorbed into blood after oral administration...
May 11, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28489029/comparative-analysis-of-the-major-chemical-constituents-in-salvia-miltiorrhiza-roots-stems-leaves-and-flowers-during-different-growth-periods-by-uplc-tq-ms-ms-and-hplc-elsd-methods
#16
Huiting Zeng, Shulan Su, Xiang Xiang, Xiuxiu Sha, Zhenhua Zhu, Yanyan Wang, Sheng Guo, Hui Yan, Dawei Qian, Jinao Duan
Salvia miltiorrhiza is a traditional Chinese herbal medicine containing multiple components that contribute to its notable bioactivities. This article investigated the distribution and dynamic changes of chemical constituents in various parts of S. miltiorrhiza from different growth periods. An ultra-high performance liquid chromatography-triple quadrupole mass spectrometer (UPLC-TQ-MS/MS) and high-performance liquid chromatography coupled with evaporative light scattering detector (HPLC-ELSD) methods were developed for accurate determination of 24 compounds (including phenolic acids, flavonoids, triterpenes, and saccharides) in S...
May 10, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28487653/chinese-herbal-medicines-attenuate-acute-pancreatitis-pharmacological-activities-and-mechanisms
#17
REVIEW
Hong Xiang, Qingkai Zhang, Bing Qi, Xufeng Tao, Shilin Xia, Huiyi Song, Jialin Qu, Dong Shang
Acute pancreatitis (AP) is a commonly occurring gastrointestinal disorder. An increase in the annual incidence of AP has been observed, and it causes acute hospitalization and high mortality. The diagnosis and treatment guidelines for AP recommend conservative medical treatments focused on reducing pancreatic secretion and secondary injury, as a primary therapeutic approach. Unfortunately, the existing treatment options have limited impact on the incidence and severity of AP due to the complex and multifaceted pathological process of this disease...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28486407/identification-of-chinese-herbal-medicines-with-electronic-nose-technology-applications-and-challenges
#18
REVIEW
Huaying Zhou, Dehan Luo, Hamid GholamHosseini, Zhong Li, Jiafeng He
This paper provides a review of the most recent works in machine olfaction as applied to the identification of Chinese Herbal Medicines (CHMs). Due to the wide variety of CHMs, the complexity of growing sources and the diverse specifications of herb components, the quality control of CHMs is a challenging issue. Much research has demonstrated that an electronic nose (E-nose) as an advanced machine olfaction system, can overcome this challenge through identification of the complex odors of CHMs. E-nose technology, with better usability, high sensitivity, real-time detection and non-destructive features has shown better performance in comparison with other analytical techniques such as gas chromatography-mass spectrometry (GC-MS)...
May 9, 2017: Sensors
https://www.readbyqxmd.com/read/28484475/de-novo-sequencing-and-transcriptome-analysis-reveal-key-genes-regulating-steroid-metabolism-in-leaves-roots-adventitious-roots-and-calli-of-periploca-sepium-bunge
#19
Jian Zhang, Xinglin Li, Fuping Lu, Shanying Wang, Yunhe An, Xiaoxing Su, Xiankuan Li, Lin Ma, Guangjian Han
Periploca sepium Bunge is a traditional medicinal plant, whose root bark is important for Chinese herbal medicine. Its major bioactive compounds are C21 steroids and periplocin, a kind of cardiac glycoside, which are derived from the steroid synthesis pathway. However, research on P. sepium genome or transcriptomes and their related genes has been lacking for a long time. In this study we estimated this species nuclear genome size at 170 Mb (using flow cytometry). Then, RNA sequencing of four different tissue samples of P...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28482853/dramatic-and-early-response-to-low-dose-steroid-in-the-treatment-of-acute-eosinophilic-myocarditis-a-case-report
#20
Yu-Wei Chen, Yu-Cheng Chang, Chieh-Shou Su, Wei-Chun Chang, Wen-Lieng Lee, Chih-Hung Lai
BACKGROUND: Eosinophilic myocarditis encompasses a variety of etiologies and the prognosis varies. For patients with a hypersensitive response to medications, high-dose corticosteroids and discontinuation of culprit medications are the main treatments. CASE PRESENTATION: We reported a young man with biopsy-proven eosinophilic myocarditis which was possibly induced by Chinese herbal medicine. His heart failure and left ventricular hypertrophy improved soon after low-dose corticosteroid...
May 8, 2017: BMC Cardiovascular Disorders
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