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https://www.readbyqxmd.com/read/29228024/detection-of-duo-schistosome-infection-from-filtered-urine-samples-from-school-children-in-zambia-after-mda
#1
Megan J Hessler, Austin Cyrs, Steven C Krenzke, El Shaimaa Mahmoud, Chummy Sikasunge, James Mwansa, Nilanjan Lodh
Schistosomiasis is one of the major Neglected Tropical Diseases (NTDs) in sub-Saharan Africa. In sub-Saharan Africa, two major human schistosome species namely Schistosoma mansoni and S. haematobium often occur sympatrically largely affecting children. Recognizing the public health impact of Schistosomiasis, the World Health Organization (WHO) is urging member states to regularly treat at least 75% and up to 100%, of all school-aged children at risk of morbidity. For control strategies based on targeted mass drug administration (MDA) to succeed it is essential to have a simple and sensitive test for monitoring the success of these interventions...
2017: PloS One
https://www.readbyqxmd.com/read/29218337/synthesis-and-photoelectrocatalytic-activity-of-in2o3-hollow-microspheres-via-a-bio-template-route-using-yeast-templates
#2
Duo Pan, Shengsong Ge, Xiyu Zhang, Xianmin Mai, Shengyao Li, Zhanhu Guo
Indium oxide (In2O3) hollow microspheres were prepared using yeast as a bio-template with the aid of a precipitation method. The yeast provided a solid frame for the deposition of In(OH)3 to form the precursor. The resulting In2O3 hollow microspheres were obtained by calcining the precursor at 650 °C. The samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption isotherms and UV-Vis diffuse reflectance spectroscopy...
December 8, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29214503/epidemiology-and-clinical-characteristics-of-human-coronaviruses-oc43-229e-nl63-and-hku1-a-study-of-hospitalized-children-with-acute-respiratory-tract-infection-in-guangzhou-china
#3
Zhi-Qi Zeng, De-Hui Chen, Wei-Ping Tan, Shu-Yan Qiu, Duo Xu, Huan-Xi Liang, Mei-Xin Chen, Xiao Li, Zheng-Shi Lin, Wen-Kuan Liu, Rong Zhou
Human coronaviruses (HCoV) OC43, 229E, NL63, and HKU1 are common respiratory viruses which cause various respiratory diseases, including pneumonia. There is a paucity of evidence on the epidemiology and clinical manifestations of these four HCoV strains worldwide. We collected 11,399 throat swabs from hospitalized children with acute respiratory tract infection from July 2009 to June 2016 in Guangzhou, China. These were tested for four strains of HCoV infection using real-time polymerase chain reaction (PCR)...
December 6, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29207749/cirrhosis-of-liver-and-diabetes-mellitus-the-diabolic-duo
#4
Thazhath Mavali Ramachandran, Aninchent Harayil Rajan Rajneesh, George Sarin Zacharia, Rajendran P Adarsh
Introduction: Cirrhosis of the liver and diabetes mellitus are two chronic illnesses with significant impact on the quality of life. Studies from different part of the world have shown the combination to be associated with higher incidence of complications of cirrhosis and reduced survival. However, data on the impact of pre-cirrhotic and post-cirrhotic diabetes on cirrhosis is minimal. Aim: The aim of the study was to determine the complications of cirrhosis patients with and without co-existent DM and to compare the relation between cirrhosis patients with antecedent DM and hepatogenous DM...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29200541/the-development-and-validation-of-the-closed-set-mandarin-sentence-cms-test
#5
Duo-Duo Tao, Qian-Jie Fu, John J Galvin, Ya-Feng Yu
Matrix-styled sentence tests offer a closed-set paradigm that may be useful when evaluating speech intelligibility. Ideally, sentence test materials should reflect the distribution of phonemes within the target language. We developed and validated the Closed-set Mandarin Sentence (CMS) test to assess Mandarin speech intelligibility in noise. CMS test materials were selected to be familiar words and to represent the natural distribution of vowels, consonants, and lexical tones found in Mandarin Chinese. Ten key words in each of five categories (Name, Verb, Number, Color, and Fruit) were produced by a native Mandarin talker, resulting in a total of 50 words that could be combined to produce 100,000 unique sentences...
September 2017: Speech Communication
https://www.readbyqxmd.com/read/29192293/digital-evaluation-of-the-fit-of-zirconia-reinforced-lithium-silicate-crowns-with-a-new-three-dimensional-approach
#6
Moritz Zimmermann, Andre Valcanaia, Gisele Neiva, Albert Mehl, Dennis Fasbinder
OBJECTIVE: Several methods for the evaluation of fit of computer-aided design/computer-assisted manufacture (CAD/CAM)-fabricated restorations have been described. In the study, digital models were recorded with an intraoral scanning device and were measured using a new three-dimensional (3D) computer technique to evaluate restoration internal fit. The aim of the study was to evaluate the internal adaptation and fit of chairside CAD/CAM-fabricated zirconia-reinforced lithium silicate ceramic crowns fabricated with different post-milling protocols...
November 30, 2017: Quintessence International
https://www.readbyqxmd.com/read/29167687/effect-of-self-adhesive-and-separate-etch-adhesive-dual-cure-resin-cements-on-the-bond-strength-of-fiber-post-to-dentin-at-different-parts-of-the-root
#7
Ehsan Mohamadian Amiri, Fariba Balouch, Faezeh Atri
Objectives: Bonding of fiber posts to intracanal dentin is challenging in the clinical setting. This study aimed to compare the effect of self-adhesive and separate etch adhesive dual cure resin cements on the bond strength of fiber post to dentin at different parts of the root. Materials and Methods: This in-vitro experimental study was conducted on 20 single-rooted premolars. The teeth were decoronated at 1mm coronal to the cementoenamel junction (CEJ), and the roots underwent root canal treatment...
May 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29166421/wear-and-fracture-strength-of-new-ceramic-resins-for-chairside-milling
#8
Karina Zierden, Johannes Acar, Peter Rehmann, Bernd Wöstmann
PURPOSE: The purpose of this in vitro study was to evaluate wear and fracture strength of chairside-milled new ceramic resins after artificial aging in a chewing simulator. MATERIALS AND METHODS: Two ceramic resins (Lava Ultimate and Vita Enamic) and two conventional ceramics (IPS Empress CAD and Celtra Duo) were tested. For analysis of wear, baseline and follow-up scans of the specimens were made, the scans were superimposed, and the wear was calculated. To determine fracture strength, the specimens were loaded until they fractured...
November 22, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29157995/in-the-ovine-pituitary-cxcr4-is-localized-in-gonadotropes-and-somatotropes-and-increases-with-elevated-serum-progesterone
#9
N S Sanchez, K E Quinn, A K Ashley, R L Ashley
The pituitary is the central endocrine regulator of reproduction and in addition to various hormones regulating its actions, other molecules, such as chemokines, influence pituitary physiology as well. Despite reports over 2 decades ago that chemokines regulate the pituitary, much of the basic biology discerning chemokine action in the pituitary is unclear. A small number of chemokines and their receptors have been localized to the pituitary, yet chemokine ligand 12 (CXCL12) and its receptor, CXCR4, have received the most attention as both are increased in human pituitary adenomas...
October 28, 2017: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/29128964/in-vivo-assessment-of-a-novel-biodegradable-ureteral-stent
#10
Alexandre A Barros, Carlos Oliveira, Ana J Ribeiro, Riccardo Autorino, Rui L Reis, Ana Rita C Duarte, Estevão Lima
PURPOSE: To perform an in vivo assessment of a newly developed biodegradable ureteral stent (BUS) produced with natural-based polymers. METHODS: The BUS is based on a patented technology combining the injection process with the use of supercritical fluid technology. Study was conducted at ICVS-University of Minho (Braga, Portugal) and a total of ten domestic pigs were used. In seven animals, the experimental BUS stent was inserted, whereas in the remaining a commercially available stent was used (6-Fr Biosoft(®) duo stents, Porges Coloplast, Denmark)...
November 11, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29117735/antioxidant-and-%C3%AE-glucosidase-inhibitory-ingredients-identified-from-jerusalem-artichoke-flowers
#11
Yan-Ming Wang, Jian-Qiang Zhao, Jun-Li Yang, Pema Tsering Idong, Li-Juan Mei, Yan-Duo Tao, Yan-Ping Shi
Jerusalem artichoke (JA, Helianthus tuberosus L.) has been researched extensively due to its wide range of uses, but there are limited studies on its flowers. In this study, we report the first detailed phytochemical study on JA flowers, which yielded 21 compounds. Compound 4 was identified as a major water-soluble yellow pigment of JA flowers. In addition, the methanol extract of JA flowers and the isolates were evaluated for their antioxidant and α-glucosidase inhibitory activities. Among the tested compounds, compound 13 showed the strongest ABTS(+) free radical scavenging activity with SC50 value of 2...
November 9, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29109538/two-novel-diterpenoid-heterodimers-bisebracteolasins-a-and-b-from-euphorbia-ebracteolata-hayata-and-the-cancer-chemotherapeutic-potential-of-bisebracteolasin-a
#12
Wen-Juan Yuan, Xiao Ding, Zhe Wang, Bi-Juan Yang, Xiao-Nian Li, Yu Zhang, Duo-Zhi Chen, Shun-Lin Li, Quan Chen, Ying-Tong Di, Haji Akber Aisa, Xiao-Jiang Hao
Rare ent-abietane-rosane diterpenoid heterodimers, Bisebracteolasins A and B (1 and 2, respectively), were isolated from the roots of Euphorbia ebracteolata Hayata. Their structures and absolute configurations were elucidated from spectroscopic data and X-ray diffraction analysis. Compounds 1 and 2 exhibited moderate cytotoxic effects against five cancer cell lines. Compound 1 showed more effective antiproliferative activities against human tumour cells, HL-60 and SMMC-7721, with IC50 values of 2.61 and 4.08 μM, respectively, than 2...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29094136/design-and-chemical-synthesis-of-eukaryotic-chromosomes
#13
Ze-Xiong Xie, Duo Liu, Bing-Zhi Li, Meng Zhao, Bo-Xuan Zeng, Yi Wu, Yue Shen, Tao Lin, Ping Yang, Junbiao Dai, Yizhi Cai, Huanming Yang, Ying-Jin Yuan
Following the discovery of the DNA double helix structure and the advancement of genome sequencing, we have entered a promising stage with regard to genome writing. Recently, a milestone breakthrough was achieved in the chemical synthesis of designer yeast chromosomes. Here, we review the systematic approaches to the de novo synthesis of designer eukaryotic chromosomes, with an emphasis on technologies and methodologies that enable design, building, testing and debugging. The achievement of chemically synthesized genomes with customized genetic features offers an opportunity to rebuild genome organization, remold biological functions and promote life evolution, which will be of great benefit for application in medicine and industrial manufacturing...
November 2, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29082412/the-biodistribution-excretion-and-potential-toxicity-of-different-sized-pd-nanosheets-in-mice-following-oral-and-intraperitoneal-administration
#14
Xiaolan Chen, Jingchao Li, Yizhuan Huang, Jingping Wei, Duo Sun, Nanfeng Zheng
Two-dimensional (2D) Pd-based nanomaterials with strong near-infrared absorption have recently shown great application prospects in cancer diagnosis and therapy. Most previous studies mainly focused on understanding the in vivo behaviors and treatment effects of these Pd-based nanomaterials after intravenous injection into mice. However, it remains unclear whether other administration routes will affect the in vivo biodistribution, excretion and potential toxicity of Pd-based nanomaterials. In this study, for the first time we systematically explored the in vivo behaviors of different-sized Pd nanosheets (NSs) (approximately 5 nm, 30 nm and 80 nm) following oral feeding and intraperitoneal injection...
October 30, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/29046953/snp-typing-using-the-hid-ion-ampliseq%C3%A2-identity-panel-in-a-southern-chinese-population
#15
Ran Li, Chuchu Zhang, Haiyan Li, Riga Wu, Haixia Li, Zhenya Tang, Chenhao Zhen, Jianye Ge, Dan Peng, Ying Wang, Hongying Chen, Hongyu Sun
In the present study, 90 autosomal single nucleotide polymorphisms (SNPs) and 34 Y chromosomal SNPs were sequenced simultaneously using HID-Ion AmpliSeq™ Identity Panel on the Ion PGM™ platform for 125 samples in a southern Chinese population. Raw data were analyzed and forensic parameters were calculated. Haplogrouping concordance was also assessed using alternative methods based on Y-SNP haplotypes and Y-STR haplotypes. The results showed that allelic imbalance occurred more frequently with low coverage while several SNPs with high coverage were also observed with poor allelic balance, including rs214955, rs430046, rs7520386, rs876724, rs9171188, rs16981290, and rs2032631...
October 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29028488/prenatal-phthalate-exposure-and-placental-size-and-shape-at-birth-a-birth-cohort-study
#16
Yuan-Duo Zhu, Hui Gao, Kun Huang, Yun-Wei Zhang, Xiu-Xiu Cai, Hui-Yuan Yao, Lei-Jing Mao, Xing Ge, Shan-Shan Zhou, Yuan-Yuan Xu, Zhong-Xiu Jin, Jie Sheng, Shuang-Qin Yan, Wei-Jun Pan, Jia-Hu Hao, Peng Zhu, Fang-Biao Tao
OBJECTIVE: There is concern over the potential placental effects of prenatal phthalate exposure, and the potential adverse effects of prenatal phthalate exposure require further study; however, few data are available in humans. We investigated the associations between phthalate exposure in each trimester and both placental size and shape at birth. METHODS: We measured the urinary concentrations of phthalate metabolites among 2725 pregnant women in the Ma'anshan Birth Cohort...
October 10, 2017: Environmental Research
https://www.readbyqxmd.com/read/28994558/flexible-co2-laser-fiber-first-look-at-the-learning-curve-required-in-gynecological-laparoscopy-training
#17
Valeria S Vanni, Jessica Ottolina, Giorgio Candotti, Laura M Castellano, Iacopo Tandoi, Francesca DE Stefano, Giorgia Poppi, Stefano Ferrari, Massimo Candiani
BACKGROUND: The advent of flexible CO2 laser fiber to gynecology arena might represent a turning point in the use of laser energy on a large-scale basis in gynecological surgery. However, there might be some concerns regarding the degree of surgical skills required to use the flexible system. The purpose of our study is to evaluate whether flexible CO2 laser fiber is technically accessible. METHODS: Fourteen residents in Obstetrics and Gynecology without surgical experience attending laparoscopic box training with both flexible CO2 laser fiber and traditional line-of-sight CO2 laser using Lumenis AcuPulse Duo CO2 laser (Lumenis, Israel) were prospectively enrolled...
October 9, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28993932/genome-wide-identification-of-cd-responsive-nramp-transporter-genes-and-analyzing-expression-of-nramp-1-mediated-by-mir167-in-brassica-napus
#18
Jin Guo Meng, Xian Duo Zhang, Shang Kun Tan, Kai Xuan Zhao, Zhi Min Yang
In plants, metal transporters are responsible for metal uptake, translocation and homeostasis. These metals include essential nutrients such as zinc (Zn) and manganese (Mn) or non-essential metals like cadmium (Cd) and lead (Pb). Although a few metal transporters have been well characterized in model plants, little is known about their functionality in rapeseed (Brassica napus). In the study, 22 NRAMP transporter genes from B. napus genome were identified and annotated using bioinformatics and high-throughput RNA-sequencing (RNA-seq)...
December 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/28967396/effect-of-saliva-contamination-and-artificial-aging-on-different-primer-cement-systems-bonded-to-zirconia
#19
João Pitta, Teresa C Branco, Jaime Portugal
STATEMENT OF PROBLEM: Saliva contamination has been shown to decrease bonding to zirconia. Adopting a less contamination-sensitive cement system may be an alternative to decontamination. PURPOSE: The purpose of this in vitro study was to assess the ability of different primer/cement systems to promote a durable bond to zirconia after saliva contamination. MATERIAL AND METHODS: Zirconia blocks (Lava Plus) (N=320) were airborne-particle abraded (50 μm Al2O3) and divided into 32 experimental groups (n=10) according to the variables in the study: saliva contamination; primer/cement system (Panavia SA [PSA]; RelyX Unicem 2 [RU2]; Bifix SE [BSE]; Panavia F2...
September 27, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28938556/abcg2-and-ncf4-polymorphisms-are-associated-with-clinical-outcomes-in-diffuse-large-b-cell-lymphoma-patients-treated-with-r-chop
#20
Duo Liu, Nan Wu, Haiming Sun, Mei Dong, Tianzhu Guo, Peng Chi, Guofu Li, Donglin Sun, Yan Jin
The impact of pharmacogenetics on predicting survival in diffuse large B-cell lymphoma (DLBCL) remains unclear. We tested 337 DLBCL patients treated with rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for 9 single nucleotide polymorphisms from 6 genes (CD20, FCGR2A, NAD(P)H, ABCC2, ABCG2 and CYP3A5). Patients who carried the NCF4 rs1883112 GG genotype showed significantly shorter progression-free survival (PFS) (P = 0.023) and event-free survival (EFS) (P < 0.001) comparing with A allele...
August 29, 2017: Oncotarget
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