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First trimester vaginal bleeding

Wanqing Ji, Weidong Li, Shanshan Mei, Ping He
OBJECTIVE: To carry out a retrospective study of the clinical features of patients with intrauterine hematoma in the second and third trimesters, and discuss the risk factors for poor pregnancy outcomes. METHODS: A total of 398 patients who underwent routine examination in our hospital from January 2011 to December 2015 were classified into normal pregnancy (NP) group (N = 265) and adverse pregnancy (AP) group (N = 133), according to their pregnancy outcomes...
September 27, 2016: Journal of Maternal-fetal & Neonatal Medicine
Kirstine Sneider, Ole Bjarne Christiansen, Iben Blaabjerg Sundtoft, Jens Langhoff-Roos
INTRODUCTION: The objective was to describe recurrence rates of second trimester miscarriage and extreme preterm delivery by phenotype and use of prophylactic cerclage in a register-based cohort. MATERIAL AND METHODS: We included women with a first second trimester miscarriage or extreme preterm delivery (16(+0) - 27(+6) gestational weeks) in Denmark in 1997-2012 (n=9602) by combined use of the Danish Medical Birth Register and the Danish National Patient Register...
September 24, 2016: Acta Obstetricia et Gynecologica Scandinavica
M Al-Memar, S Bobdiwala, G Nikolic, D Popovic, S Saso, C Stalder, S Sur, B De Moor, D Timmerman, T Bourne
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
Ayman A Al-Talib
OBJECTIVES: To study the clinical presentation and treatment outcome of molar pregnancy at a Tertiary Care Hospital in Dammam, Saudi Arabia. MATERIALS AND METHODS: Reviewed medical records of all molar pregnancy cases among all the deliveries at a tertiary care hospital in Dammam from 2005 to 2014, after approval by institutional ethical review committee. Data abstracted included patient's age, parity, presenting symptoms, gestational age at diagnosis, uterine size, ultrasonographic findings, BhCG level at the time of diagnosis and at follow-up after evacuation, and blood loss during evacuation...
September 2016: Journal of Family & Community Medicine
Jacob Mørup Schlütter, Gry Johansen, Rikke Bek Helmig, Olav Bjørn Petersen
We report 2 cases of true uterine artery aneurysms diagnosed during pregnancy. Both cases presented with nonspecific symptoms such as urethral obstruction, minimal vaginal bleeding and lower abdominal pain in the 2nd trimester. Both aneurysms were diagnosed by color Doppler ultrasound. In the first case labor was induced at 37 + 4 weeks of gestation. However, due to sudden fetal distress and maternal abdominal pain, an emergency Caesarean section was performed during labor, and 3 liters of intra-peritoneal blood were encountered upon laparotomy, secondary to a ruptured uterine artery aneurysm...
September 13, 2016: Gynecologic and Obstetric Investigation
Jay G Silverman, Donta Balaiah, Julie Ritter, Anindita Dasgupta, Sabrina C Boyce, Michele R Decker, D D Naik, Saritha Nair, Niranjan Saggurti, Anita Raj
BACKGROUND: Intimate partner violence (IPV) victimization is linked to a broad range of negative maternal health outcomes. However, it is unclear whether IPV is directly related to poor maternal outcomes or whether IPV is a marker for other forms of chronic, mundane maltreatment of women that stem from the culture of gender inequity that also gives rise to IPV. To determine the prevalence of non-violent forms of gender-based household maltreatment by husbands and in-laws (GBHM), and violence from in-laws (ILV) and husbands (IPV) against women during the peripregnancy period (during and in the year prior to pregnancy); to assess relative associations of GBHM, ILV and IPV with maternal health...
2016: Reproductive Health
Bishwajit Bhowmik
Diabetes is the most prevalent medical condition complicating pregnancy in the world. It carries both acute and long-term health consequences for the mother and her offspring. Both preexisting (type 1 and type 2) and gestational diabetes are a high-risk state for miscarriage, stillbirths and congenital malformations in early pregnancy. Like normal pregnancy, vaginal bleeding, urinary tract infection, abdominopelvic pain, nausea, and vomiting are common presenting symptoms in early pregnancy with preexisting and gestational diabetes...
September 2016: JPMA. the Journal of the Pakistan Medical Association
Bishwajit Bhowmik
Diabetes is the most prevalent medical condition complicating pregnancy in the world. It carries both acute and long-term health consequences for the mother and her offspring. Both preexisting (type 1 and type 2) and gestational diabetes are a high-risk state for miscarriage, stillbirths and congenital malformations in early pregnancy. Like normal pregnancy, vaginal bleeding, urinary tract infection, abdominopelvic pain, nausea, and vomiting are common presenting symptoms in early pregnancy with preexisting and gestational diabetes...
September 2016: JPMA. the Journal of the Pakistan Medical Association
I Dimitrov, M Konovalova, P Chaveeva, A Shterev
Abdominal pregnancies are 1.4% of all ectopic pregnancies. They are mostly complicated and usually managed by laparotomy, but laparoscopy is an alternative method which some surgeons perform instead of laparotomy, especially in early pregnancy. We reported a 29 year old woman with supra pubic pain and vaginal bleeding. After sonographic evaluations, ectopic pregnancy was diagnosed and the patient underwent laparoscopic surgery for termination of pregnancy. Laparoscopy is a successful alternative method of surgery for abdominal pregnancies in first trimester...
2016: Akusherstvo i Ginekologii︠a︡
Sheeba Marwah, Supriya Gupta, Neera Parothi Batra, Vidhu Bhasin, Veena Sarna, Nirlep Kaur
INTRODUCTION: Missed miscarriages, occurring in upto 15% of all clinically recognized pregnancies are a cause of concern for the patients. Though many researchers in the past have compared the surgical and medical approaches in management of such patients, only a few have executed an appraisal of two routes of misoprostol at equal dosages in treatment of first trimester missed miscarriages. AIM: To compare the efficacy of misoprostol by vaginal and oral route, for the management of first trimester missed abortion; and to recognize the utility of misoprostol for cervical dilation prior to any surgical termination of pregnancy...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
John W Hall, Nicolas Denne, Joseph J Minardi, Debra Williams, B J Balcik
BACKGROUND: Early pregnancy complaints in emergency medicine are common. Emergency physicians (EP) increasingly employ ultrasound (US) in the evaluation of these complaints. As a result, it is likely that rare and important diagnoses will be encountered. We report a case of fetal anencephaly diagnosed by bedside emergency US in a patient presenting with first-trimester vaginal bleeding. CASE REPORT: A 33-year-old patient at 10 weeks gestation presented with vaginal bleeding...
July 2016: Western Journal of Emergency Medicine
Katherine J Sapra, K S Joseph, Sandro Galea, Lisa M Bates, Germaine M Buck Louis, Cande V Ananth
Approximately one-third of pregnancies end in loss; however, the natural history of early pregnancy loss, including signs and symptoms preceding loss, has yet to be fully described and its underlying mechanisms fully understood. We searched PubMed/MEDLINE and Embase to identify articles with prospective ascertainment of signs and symptoms, including vaginal bleeding, nausea, and vomiting, of pregnancy loss < 20 weeks gestation in spontaneous conceptions to ascertain existing literature on symptomatology of pregnancy loss...
June 23, 2016: Reproductive Sciences
Katherine Calaway, Shana Coshal, Kristin Jones, John Coverdale, Robin Livingston
OBJECTIVES: Because of the lack of focus on the safety of electroconvulsive therapy (ECT) during the first trimester of pregnancy in current literature, we set out to assess the safety of ECT use during this vital period of fetal development. METHODS: A systematic review was conducted, and a case where ECT was employed during the first trimester was presented. Cochrane Library, Ovid MEDLINE, PsycINFO, and PubMed were independently searched by 2 authors using the following search terms: "ECT," "electroconvulsive therapy," "electroshock" combined with "pregnancy," "first trimester of pregnancy," and "teratogenicity...
June 20, 2016: Journal of ECT
Christian Pfrepper, Annelie Siegemund, Sven Hildebrandt, Juliane Kronberg, Ute Scholz, Dietger Niederwieser
Severe hereditary factor VII deficiency is a rare bleeding disorder and may be associated with a severe bleeding phenotype. We describe a pregnancy in a 33-year-old woman with compound heterozygous factor VII deficiency and a history of severe menorrhagia and mucocutaneous bleedings. After discontinuation of contraceptives, menstruation was covered with recombinant activated factor VII (rFVIIa), and during pregnancy, rFVIIa had to be administered in first trimester in doses ranging from 15 to 90 μg/kg per day because of recurrent retroplacental hematomas and vaginal bleedings...
June 14, 2016: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
M Costantino, C Guaraldi, D Costantino
OBJECTIVE: Alpha Lipoic Acid (ALA) is a safe natural molecule that exerts a selective immunomodulating activity with antioxidant and anti-inflammatory properties. This randomized controlled clinical trial (RCT) tested the effect of the vaginal administration with ALA or Progesterone, in subchorionic hematoma resorption in women with threatened miscarriage. PATIENTS AND METHODS: 400 mg of vaginal Progesterone or 10 mg of vaginal ALA were administered to sixty-two pregnant women, in the first trimester of gestation with threatened miscarriage and subchorionic hematoma...
April 2016: European Review for Medical and Pharmacological Sciences
Jennifer L Eaton, Xingqi Zhang, Ralph R Kazer
OBJECTIVE: To examine the association between first-trimester bleeding and live-birth rates in twin pregnancies conceived with in vitro fertilization (IVF). DESIGN: Retrospective cohort study. SETTING: Academic infertility practice. PATIENT(S): Women with two gestational sacs on first-trimester ultrasound after transfer of fresh embryos derived from autologous oocytes between January 1, 1999, and December 31, 2010...
July 2016: Fertility and Sterility
Max Mongelli, Chuan Lu, Shannon Reid, Nicole Stamatopoulos, Kaantharuban Sankaralingam, Ishwari Casikar, Nigel Hardy, George Condous
In this study, we tested the hypothesis that anomalous first trimester growth affects birth weight. Four hundred and fifteen women with viable singleton pregnancies at the primary transvaginal scan who had at least two crown rump length (CRL) and birth weight data were included. A linear mixed model was fitted to the Box-Cox transformed CRL values to evaluate the association between the GA and the embryonic growth. For multivariate analysis we included maternal age, height, weight, parity, number of miscarriages, vaginal bleeding, smoking, foetal gender, birth weight, small-for-gestation (SGA) and large-for gestation (LGA) categories at delivery...
March 25, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
K J Sapra, G M Buck Louis, R Sundaram, K S Joseph, L M Bates, S Galea, C V Ananth
STUDY QUESTION: What is the relationship between signs and symptoms of early pregnancy and pregnancy loss <20 weeks' gestation? SUMMARY ANSWER: Vaginal bleeding is associated with increased incidence of early pregnancy loss, with more severe bleeding and bleeding accompanied by lower abdominal cramping associated with greater incidence of loss; conversely, vomiting is associated with decreased incidence of early pregnancy loss, even in the setting of vaginal bleeding, while nausea alone is not...
April 2016: Human Reproduction
Yan Yi, Xihong Li, Yan Ouyang, Ge Lin, Guangxiu Lu, Fei Gong
OBJECTIVE: To investigate a forecasting method developed to predict first trimester pregnancy outcomes using the first routine ultrasound scan for early pregnancy on days 27-29 after ET and to determine whether to perform a repeated scan several days later based on this forecasting method. DESIGN: Prospective analysis. SETTING: Infertile patients at an assisted reproductive technology center. PATIENT(S): A total of 9,963 patients with an early singleton pregnancy after in vitro fertilization (IVF)-ET...
May 2016: Fertility and Sterility
Kanika Gupta, Bhuvaneswari Venkatesan, Meenakshisundaram Kumaresan, Tushar Chandra
INTRODUCTION: Twin pregnancy with hydatidiform mole and coexistent live fetus is a rare condition with severe maternal and fetal complications such as preeclampsia, vaginal bleeding, persistent gestational trophoblastic tumor, and fetal death. CASE PRESENTATION: We report a case of a twin pregnancy with histopathologically proven hydatidiform mole and a coexistent live fetus in a 30-year-old Indian woman diagnosed by first trimester ultrasound. DISCUSSION: Our case emphasizes the role of ultrasound in diagnosing this condition in early pregnancy...
October 2015: WMJ: Official Publication of the State Medical Society of Wisconsin
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