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Subchorionic hematoma

Disha Mittal, Rama Anand, Neha Sisodia, Smita Singh, Ratna Biswas
Placental mesenchymal dysplasia (PMD) is an uncommon vascular anomaly of the placenta characterized by placentomegaly with multicystic placental lesion on ultrasonography and mesenchymal stem villous hyperplasia on histopathology. Placental mesenchymal dysplasia should be considered in the differential diagnosis of cases of multicystic placental lesion such as molar pregnancy, chorioangioma, subchorionic hematoma, and spontaneous abortion with hydropic placental changes. However, lack of high-velocity signals inside the lesion and a normal karyotype favor a diagnosis of PMD...
January 2017: Indian Journal of Radiology & Imaging
Burcu Kasap, Ümmühani Özel Türkçü, Eren Akbaba, Behiye Sarıyıldız, Mert Küçük, Nilgün Öztürk Turhan, Gökalp Öner, Aykut Özcan
PURPOSE: To investigate the relationships of TNF-related weak inducer of apoptosis (sTWEAK), a cytokine related to the TNF superfamily, its newly described soluble receptor sCD163, and the sTWEAK/sCD163 ratio with perinatal outcomes in women with first-trimester vaginal bleeding. MATERIALS AND METHODS: Seventy (41 threatened abortion and 29 control) gestational-age-matched (6-14 weeks) pregnant women were included in the study. Antenatal complications (gestational diabetes, preeclampsia, intrauterine growth restriction, oligohydramniosis, polyhydramniosis), and perinatal outcomes (delivery mode, birth weight, delivery week) were recorded...
May 19, 2017: Journal of Maternal-fetal & Neonatal Medicine
Ryo Yamamoto, Keisuke Ishii, Aki Mabuchi, Shiyo Oota, Kazufumi Haino, Shusaku Hayashi, Takeshi Kanagawa, Nobuaki Mitsusda
AIM: To investigate the association between uterine bleeding preceding fetoscopic laser photocoagulation (FLP) and the presence of discolored amniotic fluid that impedes FLP. METHODS: A retrospective review of all multiple gestations requiring FLP at the present institution was conducted. The rate of low visibility because of discolored amniotic fluid at the beginning of FLP was compared between patients with and without a history of uterine bleeding, defined as either genital bleeding or ultrasonographically detected subchorionic hematoma...
December 2016: Journal of Obstetrics and Gynaecology Research
Veronica Giorgione, Paolo Cavoretto, Gennaro Cormio, Luca Valsecchi, Antonella Vimercati, Alessandra De Gennaro, Emanuela Rabaiotti, Massimo Candiani, Giorgia Mangili
AIM: The study aimed to describe prenatal diagnosis and the outcome of complete hydatidiform mole and coexistent normal fetus (CHMCF). METHODS: This was a retrospective case series of 13 patients with CHMCF. Prenatal diagnosis, outcome and development of gestational trophoblastic neoplasia (GTN) were reviewed. RESULTS: Ultrasound diagnosis was carried out in 12 of 13 cases at 17 ± 2.7 weeks of gestation (mean ± SD). Six patients showed abnormalities suggestive of subchorionic hematoma on first trimester ultrasonography (US)...
2017: Gynecologic and Obstetric Investigation
Qing Li, Jin Zhu, Keqin Hua
OBJECTIVE: To study the effects of subchorionic hematoma (SCH) on pregnancy outcome. METHODS: We searched publications from January 2000 to July 2015 for cohort and case-control studies evaluating subchorionic hematoma and perinatal outcomes, including spontaneous abortion, premature delivery and delivery mode. RESULTS: Data of 6 articles analyzed by meta-analysis showed that SCH group had higher rate of spontaneous abortion, while no difference in premature delivery and delivery mode, compared with threatened abortion group...
May 10, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
M Costantino, C Guaraldi, D Costantino
OBJECTIVE: Alpha Lipoic Acid (ALA) is a safe natural molecule that exerts a selective immunomodulating activity with antioxidant and anti-inflammatory properties. This randomized controlled clinical trial (RCT) tested the effect of the vaginal administration with ALA or Progesterone, in subchorionic hematoma resorption in women with threatened miscarriage. PATIENTS AND METHODS: 400 mg of vaginal Progesterone or 10 mg of vaginal ALA were administered to sixty-two pregnant women, in the first trimester of gestation with threatened miscarriage and subchorionic hematoma...
April 2016: European Review for Medical and Pharmacological Sciences
Jennifer L Eaton, Xingqi Zhang, Ralph R Kazer
OBJECTIVE: To examine the association between first-trimester bleeding and live-birth rates in twin pregnancies conceived with in vitro fertilization (IVF). DESIGN: Retrospective cohort study. SETTING: Academic infertility practice. PATIENT(S): Women with two gestational sacs on first-trimester ultrasound after transfer of fresh embryos derived from autologous oocytes between January 1, 1999, and December 31, 2010...
July 2016: Fertility and Sterility
Jianjun Zhou, Min Wu, Bin Wang, Xiaoni Hou, Junxia Wang, Hua Chen, Ningyuan Zhang, Yali Hu, Haixiang Sun
OBJECTIVE: The aim of this retrospective cohort study was to assess the effect of subchorionic hematoma (SCH) on pregnancy outcomes in IVF/ICSI patients. METHODS: We retrospectively analyzed 1097 pregnancies achieved by in vitro fertilization and embryo transfer (IVF-ET) or frozen-thawed embryo transfers (FETs) between January 2013 and June 2013 at the IVF center of Nanjing Drum Tower Hospital. The prevalence of SCH was 12.1% in this group (133/1097). We compared the pregnancy outcomes between the SCH group and non-SCH group, while the risk factors for SCH were also evaluated...
February 2017: Journal of Maternal-fetal & Neonatal Medicine
Ayaka Yamaguchi, Atsuko Taga, Saori Kamei, Michiko Wada, Yohta Fujita, Hideo Wada, Kohei Fujita
Blood coagulation factors play an essential role in pregnancy. We describe a 30-year-old pregnant woman whose course was complicated by dysfibrinogenemia with polymorphism of fibrinogen AαThr312Ala (rs6050) GG genotype. She was admitted to our hospital for genital bleeding and a huge subchorionic hematoma at 6 gestational weeks. Her first pregnancy and delivery had been uneventful, whereas her second and third pregnancies had resulted in spontaneous abortions with massive subchorionic hematomas. Her fibrinogen activity level was 125 mg/dl and this was lower than her fibrinogen antigen level...
January 2016: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
Ashley Truong, M Mercedes Sayago, William H Kutteh, Raymond W Ke
OBJECTIVE: To determine the frequency of subchorionic hematomas (SCH) in first-trimester ultrasound examinations of patients with infertility and recurrent pregnancy loss (RPL) and in patients from a general obstetric population. To determine if the method of assisted reproduction utilized or the use of anticoagulants, such as heparin and aspirin (ASA), influenced frequency of SCH. DESIGN: Prospective, cohort study. SETTING: Fertility clinic and general obstetrics clinic...
May 2016: Fertility and Sterility
G Porcaro, E Brillo, I Giardina, R Di Iorio
OBJECTIVE: The clinic use of alpha Lipoic Acid (ALA) is linked to its capability to exert antioxidant effects and, more interestingly, to counteract the pathologic changes of complex networks of cytokines, chemokines and growth factors, restoring their physiological state. The aim of this randomized controlled clinical trial was to test the contribution of oral supplementation of ALA to the standard treatment with Progesterone vaginal suppositories, in healing subchorionic hematomas in patients with threatened miscarriage...
September 2015: European Review for Medical and Pharmacological Sciences
Anna Palatnik, William A Grobman
OBJECTIVE: The objective of the study was to evaluate the association between a sonographically diagnosed subchorionic hematoma (SCH) in the first trimester and subsequent midtrimester cervical length and preterm birth. STUDY DESIGN: In this cohort study, 512 women with an SCH on their first-trimester ultrasound were compared with 1024 women without a first-trimester SCH. All women underwent routine transvaginal cervical length measurement between 18 and 22 weeks...
September 2015: American Journal of Obstetrics and Gynecology
Kozue Asato, Keiko Mekaru, Chiaki Heshiki, Hitoshi Sugiyama, Tadatugu Kinjyo, Hitoshi Masamoto, Yoichi Aoki
OBJECTIVE: Obstetric complications occur more frequently in pregnancies after in vitro fertilization (IVF). We attempted to determine the correlation between subchorionic hematoma and IVF pregnancies. STUDY DESIGN: We analyzed 194 pregnancies achieved by infertility treatment between January 2008 and February 2012 at our hospital. Among these, 67 were achieved by IVF and 127 by non-IVF approaches. We compared the frequency of subchorionic hematoma between the groups and examined the risk factors for subchorionic hematoma in the IVF group...
October 2014: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Nina Linduska, Antonia Knoezinger, Sabine Dekan, Michael Weber, Michael Hayde, Daniela Prayer, Agnes Grill
OBJECTIVE: Placental anomalies visualized at midgestation by MRI are shown to be related to pregnancy outcome. We performed a prospective cohort study to investigate the influence of placental pathologies diagnosed with fetal MRI on long-term neurodevelopmental outcome. METHODS: In our hospital-based, cross-sectional study, all fetal MRI examinations of pregnancies with vascular placental pathology (i.e. infarction with/without hemorrhage, subchorionic thrombi/hemorrhages, intervillous thrombi/hemorrhages or retroplacental hematoma) between 2003 and 2007 were included...
July 2015: Journal of Maternal-fetal & Neonatal Medicine
Anna Janowicz-Grelewska, Piotr Sieroszewski
OBJECTIVES: the aim of this retrospective study was to assess if a first trimester subchorionic hematoma (SCH) influences the pregnancy outcome and whether pv bleeding can be a prognostic factor for the pregnancy course. MATERIAL AND METHODS: the study included 185 pregnant women hospitalized due to symptoms of a threatening miscarriage. Patients were divided into 2 groups: 119 women with SCH (study group) and 66 patients with normal prenatal scan (control group), further subdivided into cases with and without pv bleeding, irrespectively of the outcome of the ultrasound scan...
November 2013: Ginekologia Polska
Jennifer Lesko, Daniela Carusi, Thomas D Shipp, Caryn Dutton
BACKGROUND: Cervical varices are an extremely rare complication of pregnancy; they can result in significant maternal morbidity secondary to acute hemorrhage. There is limited evidence to guide the management of cervical varices during termination of pregnancy. CASE: A 37-year-old woman presented with recurrent vaginal hemorrhage at 17 weeks of gestation in the setting of a dichorionic-diamniotic twin gestation, an anterior placenta previa, a subchorionic hematoma visible on ultrasound examination, and prominent cervical varices...
February 2014: Obstetrics and Gynecology
Ann E Podrasky, Marcia C Javitt, Phyllis Glanc, Theodore Dubinsky, Mukesh G Harisinghani, Robert D Harris, Nadia J Khati, Donald G Mitchell, Pari V Pandharipande, Harpreet K Pannu, Thomas D Shipp, Cary Lynn Siegel, Lynn Simpson, Darci J Wall, Jade J Wong-You-Cheong, Carolyn M Zelop
Vaginal bleeding occurring in the second or third trimesters of pregnancy can variably affect perinatal outcome, depending on whether it is minor (i.e. a single, mild episode) or major (heavy bleeding or multiple episodes.) Ultrasound is used to evaluate these patients. Sonographic findings may range from marginal subchorionic hematoma to placental abruption. Abnormal placentations such as placenta previa, placenta accreta and vasa previa require accurate diagnosis for clinical management. In cases of placenta accreta, magnetic resonance imaging is useful as an adjunct to ultrasound and is often appropriate for evaluation of the extent of placental invasiveness and potential involvement of adjacent structures...
December 2013: Ultrasound Quarterly
Shigeru Aoki, Megumi Inagaki, Kentaro Kurasawa, Mika Okuda, Tsuneo Takahashi, Fumiki Hirahara
OBJECTIVE: To examine the clinicopathological characteristics of pregnant women who presented with intermittent hemorrhage occurring throughout pregnancy until delivery. METHOD: A total of 24 women with intermittent hemorrhage occurring throughout pregnancy were categorized into two groups, a group with persistent subchorionic hematoma (PSH) and another with chronic abruption (CA), and the pregnancy outcomes were compared between the two groups. The data were expressed as medians (range)...
February 2014: Archives of Gynecology and Obstetrics
Ramen H Chmait, Lisa M Korst, Arlyn Llanes, Patrick Mullin, Richard H Lee, Joseph G Ouzounian
OBJECTIVE: To identify perioperative risk factors for preterm delivery (PTD) in laser-treated patients with twin-twin transfusion syndrome (TTTS). STUDY DESIGN: Twin-twin transfusion syndrome patients who underwent laser surgery were followed prospectively. Univariate and multivariate analyses were performed to identify gestational and surgical characteristics associated with preterm delivery. RESULTS: Of 318 eligible patients, the mean (SD) gestational age of delivery was 32...
September 2013: American Journal of Obstetrics and Gynecology
Abdulmohsen Alanjari, Emily Wright, Sarah Keating, Greg Ryan, John Kingdom
OBJECTIVES: To review the association between ultrasound findings, placental pathology, and prognosis in pregnancies complicated by massive subchorionic thrombohematoma (MTH)/Breus' mole. METHOD: We identified 14 cases of MTH from January 2004 to December 2012. MTH was defined by >1 cm thickness hematoma and extensive (≥50%) involvement of the fetal surface of the placenta. Patient information, details of initial presentation, and perinatal outcome were obtained from the manual and electronic chart records...
October 2013: Prenatal Diagnosis
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