keyword
MENU ▼
Read by QxMD icon Read
search

Yersinia

keyword
https://www.readbyqxmd.com/read/28418764/disease-surveillance-of-california-ground-squirrels-spermophilus-beecheyi-in-a-drive-through-zoo-in-oregon-usa
#1
Julia Ter Beest, Andrew Cushing, Modesto McClean, Wendy Hsu, Robert Bildfell
Rodents and other small wild mammals are often considered to be pests and vectors for disease in zoos that house small populations of valuable threatened and endangered animals. In 2005, three nonhuman primates at a drive-through zoo in Oregon, USA, acquired tularemia from an unknown source. Due to an abundance of California ground squirrels ( Spermophilus beecheyi ) on zoo grounds, we instituted serosurveillance of this species from July through September 2008 to determine the prevalence of antibodies against pathogens considered to be potentially transmissible to collection animals...
April 18, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28417359/an-improved-kinetic-assay-for-the-characterization-of-metal-dependent-pectate-lyases
#2
Darryl R Jones, Richard McLean, D Wade Abbott
Pectate lyases are a subset of polysaccharide lyases (PLs) that specifically utilize a metal dependent β-elimination mechanism to cleave glyosidic bonds in homogalacturonan (HG; α-D-1,4-galacturonic acid). Most commonly, PLs harness calcium for catalysis; however, some PL families (e.g., PL2 and PL22) display preferences for transitional metals. Deploying alternative metals during β-elimination is correlated with signature coordination pocket chemistry, and is reflective of the evolution, functional specialization, and cellular location of PL activity...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28408689/draft-genome-sequences-of-four-yersinia-enterocolitica-strains-isolated-from-wild-ungulate-carcasses
#3
Guerrino Macori, Angelo Romano, Daniela Adriano, Elisabetta Razzuoli, Daniela Manila Bianchi, Silvia Gallina, Alberto Bellio, Lucia Decastelli
This study describes the draft genome sequences of four Yersinia enterocolitica strains, originally isolated from ungulate carcasses. These isolates were typed biochemically and two were determined to be highly virulent (biotype 1B). The draft genome sequences had a mean size of 4.77 Mb and a mean G+C content of 47.1%.
April 13, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28405017/lectin-pathway-factors-in-patients-suffering-from-juvenile-idiopathic-arthritis
#4
Katarzyna Kasperkiewicz, Łukasz Eppa, Anna S Świerzko, Marcin A Bartłomiejczyk, Zbigniew M Żuber, Katarzyna Siniewicz-Luzeńczyk, Elżbieta Mężyk, Misao Matsushita, Leokadia Bąk-Romaniszyn, Krzysztof Zeman, Mikael Skurnik, Maciej Cedzyński
Both complement activation and certain infections (including those with Yersinia sp.) may contribute to the pathogenesis of juvenile idiopathic arthritis (JIA). We investigated factors specific for the lectin pathway of complement: mannose-binding lectin (MBL), ficolins and associated serine protease-2 (MASP-2), in 144 patients and 98 controls. 106 patients had oligoarticular disease and 38 had polyarticular disease. In 51 patients (out of 133 tested), Yersinia-reactive antibodies were found (JIA Ye+ group)...
April 13, 2017: Immunology and Cell Biology
https://www.readbyqxmd.com/read/28403184/low-prevalence-of-human-enteropathogenic-yersinia-spp-in-brown-rats-rattus-norvegicus-in-flanders
#5
Lieze Oscar Rouffaer, Kristof Baert, Anne-Marie Van den Abeele, Ivo Cox, Gerty Vanantwerpen, Lieven De Zutter, Diederik Strubbe, Katleen Vranckx, Luc Lens, Freddy Haesebrouck, Michel Delmée, Frank Pasmans, An Martel
Brown rats (Rattus norvegicus) have been identified as potential carriers of Yersinia enterocolitica and Y. pseudotuberculosis, the etiological agents of yersiniosis, the third most reported bacterial zoonosis in Europe. Enteropathogenic Yersinia spp. are most often isolated from rats during yersiniosis cases in animals and humans, and from rats inhabiting farms and slaughterhouses. Information is however lacking regarding the extent to which rats act as carriers of these Yersinia spp.. In 2013, 1088 brown rats across Flanders, Belgium, were tested for the presence of Yersinia species by isolation method...
2017: PloS One
https://www.readbyqxmd.com/read/28400007/evaluation-of-virulence-genes-in-yersinia-enterocolitica-strains-using-sybr-green-real-time-pcr
#6
Maria Francesca Peruzy, Nicoletta Murru, Anna Giannina Perugini, Federico Capuano, Elisabetta Delibato, Raffaelina Mercogliano, Hannu Korkeala, Yolande Therese Rose Proroga
Yersinia enterocolitica comprises six biotypes 1A, 1B, 2, 3, 4, and 5. The virulence of the strains belonging to biotypes 1B and 2-5 depends on the presence of both chromosomal and plasmid-borne genes. Strains belonging to biotype 1A do not carry the virulence plasmid pYV. However, they carry other virulence genes, such as ystB and hreP. The aim of this study was to investigate the distribution of yadA, virF, inv, ystA, ystB, myfA, hreP and ymoA virulence genes in Y. enterocolitica strains in order to select the target genes that could be used for the development of a probe-specific real-time PCR to determine the presence of Y...
August 2017: Food Microbiology
https://www.readbyqxmd.com/read/28399281/potential-roles-of-pigs-small-ruminants-rodents-and-their-flea-vectors-in-plague-epidemiology-in-sinda-district-eastern-zambia
#7
Stanley S Nyirenda, Bernard M Hang'ombe, Bukheti S Kilonzo, Henry L Kangwa, Evans Mulenga, Ladslav Moonga
A cross-sectional study was conducted in the Eastern part of Zambia that previously reported a plague outbreak. The aim of the study was to evaluate the potential role of pigs, goats, and sheep as sero-surveillance hosts for monitoring plague, and to investigate the flea vectors and potential reservoir hosts to establish the current status of plague endemicity in the district. Serum samples were collected from 96 rodents, 10 shrews, 245 domestic pigs, 232 goats, and 31 sheep, whereas 106 organs were eviscerated from rodents and shrews...
February 4, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28398677/preparing-for-biological-threats-addressing-the-needs-of-pregnant-women
#8
REVIEW
Amelia K Watson, Sascha Ellington, Christina Nelson, Tracee Treadwell, Denise J Jamieson, Dana M Meaney-Delman
Intentional release of infectious agents and biological weapons to cause illness and death has the potential to greatly impact pregnant women and their fetuses. We review what is known about the maternal and fetal effects of seven biological threats: Bacillus anthracis (anthrax); variola virus (smallpox); Clostridium botulinum toxin (botulism); Burkholderia mallei (glanders) and Burkholderia pseudomallei (melioidosis); Yersinia pestis (plague); Francisella tularensis (tularemia); and Rickettsia prowazekii (typhus)...
March 15, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28398546/the-cdi-toxin-ofyersinia-kristensenii-is-a-novel-bacterial-member-of-the-rnase-a-superfamily
#9
Gaëlle Batot, Karolina Michalska, Greg Ekberg, Ervin M Irimpan, Grazyna Joachimiak, Robert Jedrzejczak, Gyorgy Babnigg, Christopher S Hayes, Andrzej Joachimiak, Celia W Goulding
Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Here, we present the crystal structure of the CdiA-CT/CdiIYkris complex from Yersinia kristensenii ATCC 33638...
April 10, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28396545/salicylidene-acylhydrazides-and-hydroxyquinolines-act-as-inhibitors-of-type-three-secretion-systems-in-pseudomonas-aeruginosa-by-distinct-mechanisms
#10
Ahalieyah Anantharajah, Julien M Buyck, Charlotta Sundin, Paul M Tulkens, Marie-Paule Mingeot-Leclercq, Françoise Van Bambeke
Type three secretion systems (T3SS) are major virulence factors in Gram-negative bacteria. Pseudomonas aeruginosa expresses two T3SS, namely an injectisome (iT3SS) translocating effector proteins in the host cell cytosol, and a flagellum (fT3SS) insuring bacterial motility. Inhibiting these systems is an appealing therapeutic strategy for acute infections. This study examines the protective effects of the salicylidene acylhydrazide INP0341 and of the hydroxyquinoline INP1750 (previously described as T3SS inhibitors in other species) towards cytotoxic effects of P...
April 10, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28395471/-dynamics-of-f1-antibody-responses-to-yersinia-pestis-infection-in-rhombomys-opimus
#11
W W Meng, X H Wang, T Luo, B Li, Q G Wang, R Guo, X Dai, Y J Zhang
Objective: To observe the dynamics of antibody response in great gerbils infected with Yersinia pestis in experiment. Method: A total of 211 great gerbils were captured in the southern margin of plague natural focus of Junggar Basin of the Xinjiang Uygur Autonomous Region in 2011. Among them, there were 167 great gerbils without infection of Y. pestis and 44 great gerbils infected by Y.pestis. Y.pestis No. 2504 was employed for this experimental strain, which was strong toxic strain with negativity in the reduction experiment of nitrate...
April 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28393629/exploring-the-sequence-structure-function-relationship-for-the-intrinsically-disordered-%C3%AE-%C3%AE-crystallin-hahellin
#12
Meng Gao, Fei Yang, Lei Zhang, Zhengding Su, Yongqi Huang
βγ-Crystallins are a superfamily of proteins containing crystallin-type Greek key motifs. Some βγ-crystallin domains have been shown to bind Ca(2+). Hahellin is a newly identified intrinsically disordered βγ-crystallin domain from Hahella chejuensis. It folds into a typical βγ-crystallin structure upon Ca(2+) binding and acts as a Ca(2+)-regulated conformational switch. Besides Hahellin, another two putative βγ-crystallins from Caulobacter crescentus and Yersinia pestis are shown to be partially disordered in their apo-form and undergo large conformational changes upon Ca(2+) binding, although whether they acquire a βγ-crystallin fold is not known...
April 13, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28387154/production-of-polyhydroxyalkanoates-pha-using-sludge-from-different-wastewater-treatment-processes-and-the-potential-for-medical-and-pharmaceutical-applications
#13
Wai Lam, Yujie Wang, Pui Ling Chan, Shun Wan Chan, Yiu Fai Tsang, Hong Chua, Peter Hoi Fu Yu
In this study, seven strains of bacteria with polyhydroxyalkanoates (PHA)-producing ability (i.e. Bacillus cereus, Pseudomonas putida, Bacillus pumilus, Pseudomona huttiensis, Yersinia frederiksenii, Aeromonas ichthiosmia, and Sphingopyxis terrae) were isolated from various waste treatment plants in Hong Kong. Simultaneous wastewater treatment and PHA accumulation were successfully achieved in the bioreactors using isolated bacteria from different sludges. At the organic loading less than 13,000 ppm, more than 95% of chemical oxygen demand (COD) was removed by the isolated strains before the decrease of PHA accumulation...
April 20, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28385652/hmus-from-yersinia-pseudotuberculosis-is-a-non-canonical-heme-degrading-enzyme-to-acquire-iron-from-heme
#14
Masato Onzuka, Yukari Sekine, Takeshi Uchida, Koichiro Ishimori, Shin-Ichi Ozaki
Some Gram-negative pathogens import host heme into the cytoplasm and utilize it as an iron source for their survival. We report here that HmuS, encoded by the heme utilizing system (hmu) locus, cleaves the protoporphyrin ring to release iron from heme. A liquid chromatography/mass spectrometry analysis revealed that the degradation products of this reaction are two biliverdin isomers that result from transformation of a verdoheme intermediate. This oxidative heme degradation by HmuS required molecular oxygen and electrons supplied by either ascorbate or NADPH...
April 3, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28384062/fleas-of-black-footed-ferrets-and-their-potential-role-in-the-movement-of-plague
#15
Erica L Mize, Shaun M Grassel, Hugh B Britten
Sylvatic plague is one of the major impediments to the recovery of the black-footed ferret ( Mustela nigripes ) because it decimates their primary prey species, prairie dogs ( Cynomys spp.), and directly causes mortality in ferrets. Fleas are the primary vector of Yersinia pestis , the causative agent of sylvatic plague. The goal of this research was to better understand the flea fauna of ferrets and the factors that might influence flea abundance on ferrets. Fleas from ferrets were tested for Y. pestis in a post hoc assessment to investigate the plausibility that some ferrets could act as incidental transporter hosts of fleas infected with Y...
April 6, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28380351/local-inflammatory-cues-regulate-differentiation-and-persistence-of-cd8-tissue-resident-memory-t-cells
#16
Tessa Bergsbaken, Michael J Bevan, Pamela J Fink
Many pathogens initiate infection at mucosal surfaces, and tissue-resident memory T (Trm) cells play an important role in protective immunity, yet the tissue-specific signals that regulate Trm differentiation are poorly defined. During Yersinia infection, CD8(+) T cell recruitment to areas of inflammation within the intestine is required for differentiation of the CD103(-)CD69(+) Trm subset. Intestinal proinflammatory microenvironments have elevated interferon (IFN)-β and interleukin-12 (IL-12), which regulated Trm markers, including CD103...
April 4, 2017: Cell Reports
https://www.readbyqxmd.com/read/28379405/unique-case-of-disseminated-plague-with-multifocal-osteomyelitis
#17
Leidy Tovar Padua, Amanda Kamali, Hannah Kim, Nicole M Green, Rachel Civen, Benjamin Schwartz, Paul Krogstad, Jaime Deville, Nava Yeganeh, Debra Lugo, Amira Baker, Priya Soni, Catherine Cho, Natalia Svircic, Sarah Dry, Leanne Seeger, Jessica Lloyd, Grace Deukmedjian, Richard Bowen, Gillian Hale, Sherif R Zaki, Paul Mead, Karin Nielsen-Saines
Plague is a disease caused by Yersinia pestis. Septicemic and pneumonic plague have a high mortality rate if untreated. Here we describe the challenges of accurately diagnosing a nonfatal pediatric case of septicemic plague with involvement of multiple organs; to our knowledge, the first documented case of multifocal plague osteomyelitis.
April 4, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28378975/a-study-of-single-nucleotide-polymorphism-in-the-ystb-gene-of-yersinia-enterocolitica-strains-isolated-from-various-wild-animal-species
#18
Agata Bancerz-Kisiel, Anna Szczerba-Turek, Aleksandra Platt-Samoraj, Maria Michalczyk, Wojciech Szweda
INTRODUCTION AND OBJECTIVE: Y. enterocolitica is the causative agent of yersiniosis. The objective of the article was a study of single nucleotide polymorphism in the ystB gene of Y. enterocolitica strains isolated from various wild animal species. MATERIALS AND METHOD: High-resolution melting (HRM) analysis was applied to identify single nucleotide polymorphism (SNP) of ystB gene fragments of 88 Y. enterocolitica biotype 1A strains isolated from wild boar, roe deer, red deer and wild ducks...
March 1, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28378044/yersinia-pseudotuberculosis-supports-th17-differentiation-and-limits-de-novo-regulatory-t-cell-induction-by-directly-interfering-with-t-cell-receptor-signaling
#19
Maria Pasztoi, Agnes Bonifacius, Joern Pezoldt, Devesha Kulkarni, Jana Niemz, Juhao Yang, René Teich, Janina Hajek, Fabio Pisano, Manfred Rohde, Petra Dersch, Jochen Huehn
Adaptive immunity critically contributes to control acute infection with enteropathogenic Yersinia pseudotuberculosis; however, the role of CD4(+) T cell subsets in establishing infection and allowing pathogen persistence remains elusive. Here, we assessed the modulatory capacity of Y. pseudotuberculosis on CD4(+) T cell differentiation. Using in vivo assays, we report that infection with Y. pseudotuberculosis resulted in enhanced priming of IL-17-producing T cells (Th17 cells), whereas induction of Foxp3(+) regulatory T cells (Tregs) was severely disrupted in gut-draining mesenteric lymph nodes (mLNs), in line with altered frequencies of tolerogenic and proinflammatory dendritic cell (DC) subsets within mLNs...
April 4, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28377623/a-starvation-induced-regulator-rovm-acts-as-a-switch-for-planktonic-biofilm-state-transition-in-yersinia-pseudotuberculosis
#20
Ruoxi Zhao, Yunhong Song, Qingyun Dai, Yiwen Kang, Junfeng Pan, Lingfang Zhu, Lei Zhang, Yao Wang, Xihui Shen
The transition between the planktonic state and the biofilm-associated state is a key developmental decision for pathogenic bacteria. Biofilm formation by Yersinia pestis is regulated by hmsHFRS genes (β-1, 6-N-acetyl-D-glucosamine synthesis operon) in its flea vector and in vitro. However, the mechanism of biofilm formation in Yersinia pseudotuberculosis remains elusive. In this study, we demonstrate that the LysR-type regulator RovM inversely regulates biofilm formation and motility in Y. pseudotuberculosis by acting as a transcriptional regulator of these two functions...
April 4, 2017: Scientific Reports
keyword
keyword
2488
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"