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https://www.readbyqxmd.com/read/29329460/survey-of-parasitic-bacteria-in-bat-bugs-colorado
#1
Clifton D McKee, Lynn M Osikowicz, Teresa R Schwedhelm, Ying Bai, Kevin T Castle, Michael Y Kosoy
Bat bugs (Cimex adjunctus Barber) (Hemiptera: Cimicidae) collected from big brown bats (Eptesicus fuscus Palisot de Beauvoir) in Colorado, United States were assessed for the presence of Bartonella, Brucella, and Yersinia spp. using molecular techniques. No evidence of Brucella or Yersinia infection was found in the 55 specimens collected; however, 4/55 (7.3%) of the specimens were positive for Bartonella DNA. Multi-locus characterization of Bartonella DNA shows that sequences in bat bugs are phylogenetically related to other Bartonella isolates and sequences from European bats...
January 10, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29325864/infections-genetic-and-environmental-factors-in-pathogenesis-of-autoimmune-thyroid-diseases
#2
REVIEW
Sanjeev Kumar Shukla, Govind Singh, Shahzad Ahmad, Prabhat Pant
In Autoimmune disease a combination of infection, genetic and environmental factors causes an autoimmune response to the thyroid gland (characterized by lymphocytic infiltrations), thyroid stimulating hormone receptor (TSHR) and different thyroid antigens. Graves' and Hashimoto disease are autoimmune disorders with genetic predisposition. CD40 that stimulates the proliferation and differentiation of lymphocytes is an essential immunomodulatory component for follicular cells in the thyroid and the cell that present the antigen...
January 8, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29319752/effectiveness-of-aqueous-and-hydroalcoholic-extracts-of-acanthospermum-australe-loefl-kuntze-against-diarrhea-inducing-bacteria
#3
R Mallmann, E M Ethur, P Bianchetti, D Faleiro, L Hoehne, M I Goettert
Leaves and roots of Acanthospermum australe (Asteraceae) have been used in Brazilian folk medicine for the treatment of various ailments including diarrhea, skin diseases, blennorrhagia, dyspepsia, parasitic worms and malaria. The aim of study was to characterize the chemical profiles of the aqueous and hydroalcoholic extracts of leaves and roots of A. australe, and to evaluate their antimicrobial activities against diarrhea-inducing bacteria (Enterococcus faecalis, Shigella dysenteriae and Yersinia enterocolitica), as well as their cytotoxic properties...
January 8, 2018: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/29318122/the-resistance-to-plague-infection-among-meriones-persicus-from-endemic-and-non-endemic-regions-in-iran-the-role-of-gut-microbiota
#4
Mehdi Assmar, Marjan Keypour, Mehdi Rohani, Ehsan Mostafavi, Dariush Daneshvar Farhud
Background: The present study was conducted approximately 40 years ago, but its results have not been released. At the time of this study, the importance of the gut microbiota was not fully understood. Methods: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in Iran, were compared in a disease endemic area (Akanlu, Hamadan, western Iran) and a non-endemic zone (Telo, Tehran, Iran) from 1977 to 1981. Results: This study was able to transmit the resistance to Y...
January 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29313242/cost-of-illness-for-five-major-foodborne-illnesses-and-sequelae-in-sweden
#5
Kristian Sundström
OBJECTIVES: The main objective of this study was to derive cost estimates of five major foodborne illnesses (campylobacteriosis, salmonellosis, enterohemorrhagic Escherichia coli (EHEC), yersiniosis and shigellosis) in Sweden. These estimates provide a necessary contribution to perform future cost-benefit analyses aimed at reducing the burden of foodborne disease. A secondary aim was to obtain estimates of the true number of cases that occur in the community, thus providing necessary ground for calculating costs...
January 8, 2018: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/29311457/-intestinal-microbiota-in-migrating-barn-swallows-around-osaka
#6
Takehiko Kenzaka, Kenji Kataoka, Takashi Fujimitsu, Katsuji Tani
 Migratory birds are considered as vectors of infectious diseases, owing to their potential for transmitting pathogens over large distances. The populations of barn swallow (Hirundo rustica) migrate from Southeast Asia to the Japanese mainland during spring and migrate back to Southeast Asia during autumn. This migratory population is estimated to comprise approximately hundreds to thousands of individuals per year. However, to date, not much is known about the gastrointestinal microbiota of the barn swallow...
2018: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/29307129/identification-and-characterization-of-yersinia-enterocolitica-strains-isolated-from-pig-tonsils-at-slaughterhouse-in-central-italy
#7
Patrizia Centorame, Nadia Sulli, Cristina De Fanis, Orazio Vincenzo Colangelo, Fabrizio De Massis, Annamaria Conte, Tiziana Persiani, Cristina Marfoglia, Silvia Scattolini, Francesco Pomilio, Alfreda Tonelli, Vincenza Annunziata Prencipe
Yersinia enterocolitica causes foodborne disease in humans and infections are usually acquired from contaminated raw or undercooked pork. Pigs are considered the primary reservoir of human pathogenic bio-serotypes. A total of 376 tonsil tissue samples collected after evisceration and cutting from pig carcasses were tested for Yersinia enterocolitica. Animals came from an abattoir located in the Abruzzo region, Italy. Yersinia enterocolitica was isolated from 35 out of 376 (9.31%) samples. A total of 47 strains were isolated, the prevalent bio-serotype was 4÷O:3 (95...
December 29, 2017: Veterinaria Italiana
https://www.readbyqxmd.com/read/29285573/bacterial-lpx-motif-harboring-virulence-factors-constitute-a-species-spanning-family-of-cell-penetrating-effectors
#8
Stefanie Norkowski, Britta Körner, Lilo Greune, Anne-Sophie Stolle, Marie-Luise Lubos, Philip R Hardwidge, M Alexander Schmidt, Christian Rüter
Effector proteins are key virulence factors of pathogenic bacteria that target and subvert the functions of essential host defense mechanisms. Typically, these proteins are delivered into infected host cells via the type III secretion system (T3SS). Recently, however, several effector proteins have been found to enter host cells in a T3SS-independent manner thereby widening the potential range of these virulence factors. Prototypes of such bacteria-derived cell-penetrating effectors (CPEs) are the Yersinia enterocolitica-derived YopM as well as the Salmonella typhimurium effector SspH1...
December 28, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29283703/growth-of-yersinia-pseudotuberculosis-strains-at-different-temperatures-ph-values-and-nacl-and-ethanol-concentrations
#9
Riikka Keto-Timonen, Anna Pöntinen, Mariella Aalto-Araneda, Hannu Korkeala
Maximum growth temperature and growth limits in Luria-Bertani broth at different pH values and NaCl and ethanol concentrations were determined for 49 Yersinia pseudotuberculosis strains representing serotypes O:1, O:2, O:3, O:4, and O:5. In addition, the ability of the strains to grow at 0°C and the growth parameters at 1°C were determined. The maximum growth temperatures measured by Gradiplate temperature incubator varied between 42.2 and 43.7°C. All strains were able to grow at 0°C in Luria-Bertani broth within 17 days of incubation...
January 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29282608/dietary-application-of-the-probiotic-lactobacillus-plantarum-426951-enhances-immune-status-and-growth-of-rainbow-trout-oncorhynchus-mykiss-vaccinated-against-yersinia-ruckeri
#10
Mehdi Soltani, Komael Pakzad, Ali Taheri-Mirghaed, Saeed Mirzargar, Seyed Pezhman Hosseini Shekarabi, Parasto Yosefi, Narges Soleymani
This study was aimed to assess the effect of oral application of Lactobacillus plantarum (2 × 107 CFU g-1 feed) as a probiotic on growth performance and immune status of vaccinated rainbow trout (29.5 ± 2 g) to yersiniosis at 16 ± 2 °C for 72 days. Fish were randomly allocated into 12 fiber glass tanks (4100 L) at a density of 80 fish per tank (240 fish per treatment). The results revealed that the activity of lysozyme and alkaline phosphatase was significantly higher in immunized fish fed with diet supplemented with probiotic (vaccine +probiotic) than that in the immunized group fed with basal diet (vaccine group) while no significant differences in levels of hematological parameters, complements, total IgM, proteins, and the intestine lactic acid bacteria (LAB) were detected...
December 27, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29281672/effects-of-urbanization-on-host-pathogen-interactions-using-yersinia-in-house-sparrows-as-a-model
#11
Lieze Oscar Rouffaer, Diederik Strubbe, Aimeric Teyssier, Noraine Salleh Hudin, Anne-Marie Van den Abeele, Ivo Cox, Roel Haesendonck, Michel Delmée, Freddy Haesebrouck, Frank Pasmans, Luc Lens, An Martel
Urbanization strongly affects biodiversity, altering natural communities and often leading to a reduced species richness. Yet, despite its increasingly recognized importance, how urbanization impacts on the health of individual animals, wildlife populations and on disease ecology remains poorly understood. To test whether, and how, urbanization-driven ecosystem alterations influence pathogen dynamics and avian health, we use house sparrows (Passer domesticus) and Yersinia spp. (pathogenic for passerines) as a case study...
2017: PloS One
https://www.readbyqxmd.com/read/29277661/crystal-structure-of-d-glycero-%C3%AE-d-manno-heptose-1-phosphate-guanylyltransferase-from-yersinia-pseudotuberculosis
#12
Hyojin Kim, Jimin Park, Suwon Kim, Dong Hae Shin
The Gram-negative bacterium Yersinia pseudotuberculosis is the causative agent of yersiniosis. d-glycero-α-d-manno-heptose-1-phosphate guanylyltransferase (HddC) is the fourth enzyme of the GDP-d-glycero-α-d-manno-heptose biosynthesis pathway which is important for the virulence of the microorganism. Therefore, HddC is a potential target of antibiotics against yersiniosis. In this study, HddC from the synthesized HddC gene of Y. pseudotuberculosis has been expressed, purified, crystallized. Synchrotron X-ray data from a selenomethionine-substituted HddC crystal were also collected and its structure was determined at 2...
December 22, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29276773/comparison-of-zoonotic-bacterial-agents-in-fleas-collected-from-small-mammals-or-host-seeking-fleas-from-a-ugandan-region-where-plague-is-endemic
#13
Ying Bai, Lynn M Osikowicz, Michael Y Kosoy, Rebecca J Eisen, Linda A Atiku, Joseph T Mpanga, Karen A Boegler, Russell E Enscore, Kenneth L Gage
Fleas (n = 407) were collected from small mammals trapped inside huts and surroundings of homesteads in five villages within the Arua and Zombo districts of Uganda. The most common flea species were Dinopsyllus lypusus (26%) and Xenopsylla cheopis (50%). Off-host fleas (n = 225) were collected inside huts by using Kilonzo flea traps. The majority of the off-host fleas were Ctenocephalides felis (80%). All fleas were examined for the presence of Bartonella spp., Rickettsia spp., and Yersinia spp. Bartonella DNA was detected in 91 fleas, with an overall prevalence of 14%...
November 2017: MSphere
https://www.readbyqxmd.com/read/29260747/-identification-of-shiga-toxin-in-patients-with-acute-intestinal-infections-in-the-presence-of-mono-and-mixed-o-antigens-of-pathogens
#14
O F Belaia, Yu V Yudina, E V Volchkova, O A Payevskaya, Yu A Belaya, N M Gyulazyan, S N Zuyevskaya
AIM: To investigate the time course of changes in the detection rates and levels of Shiga toxin antigen (STA) in their stool and middle-molecule circulating immune complexes (CICs) containing IgG (IgG CIC) in patients with acute intestinal infections (AIIs) in the presence of the body's circulation of mono- and mixed-LPS/O-antigens of intestinal pathogens. SUBJECTS AND METHODS: A total of 147 patients aged 15 to 55 years who had been hospitalized with AIIs were examined...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29258816/the-y-bercovieri-anbu-crystal-structure-sheds-light-on-the-evolution-of-highly-pseudo-symmetric-multimers
#15
Anna Piasecka, Honorata Czapinska, Marie-Theres Vielberg, Roman Szczepanowski, Reiner Kiefersauer, Simon Reed, Michael Groll, Matthias Bochtler
Anbu (ancestral β-subunit) is homologous to HslV and 20S proteasomes. Based on its phylogenetic distribution and sequence clustering, Anbu has been proposed as the "ancestral" form of proteasomes. Here, we report biochemical data, small-angle X-ray scattering (SAXS) results, negative stain electron microscopy (EM) micrographs, and a crystal structure of the Anbu particle from Yersinia bercovieri (YbAnbu). All data are consistent with YbAnbu forming defined 12-14 subunit multimers that differ in shape from both HslV and 20S proteasomes...
December 16, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29236304/enterovirus-detection-in-patients-with-acute-gastroenteritis-in-switzerland
#16
Rainer Gosert, Ulrich Heininger, Hans H Hirsch
Acute gastroenteritis (GE) has a major impact on morbidity and mortality worldwide, yet comprehensive data regarding infectious agents including enteroviruses are scarce. We hypothesized that enteroviruses constitute a significant cause of acute GE. We analyzed 677 stool samples from 504 patients, which had been submitted for suspected infectious GE. 0.2 ml of stool suspension was extracted using the Abbott m2000 sp robot and analysed by multiplex nucleic acid testing (NAT) using the Luminex xTAG gastrointestinal pathogen panel (GPP) as well as by specific NATs detecting enteroviruses and polioviruses...
December 13, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29232397/distribution-and-prevalence-of-vector-borne-diseases-in-california-chipmunks-tamias-spp
#17
Mary H Straub, Austin N Roy, Amanda Martin, Kathleen E Sholty, Nicole Stephenson, Janet E Foley
California, with 13 chipmunk (Tamias) species, has more than any other state or country, occupying habitats ranging from chaparral to the high peaks of the Sierra Nevada. Chipmunks host zoonotic pathogens including Yersinia pestis, Anaplasma phagocytophilum, relapsing fever (RF) Borrelia spp., Borrelia burgdorferi, and spotted fever group (SFG) Rickettsia species. Chipmunk species are often not differentiated by public health workers, yet different species utilize different ecological niches and may have intrinsically different capacities for maintaining vector-borne pathogens and infecting vectors...
2017: PloS One
https://www.readbyqxmd.com/read/29227994/low-cost-low-tech-snp-genotyping-tools-for-resource-limited-areas-plague-in-madagascar-as-a-model
#18
Cedar L Mitchell, Voahangy Andrianaivoarimanana, Rebecca E Colman, Joseph Busch, Heidie Hornstra-O'Neill, Paul S Keim, David M Wagner, Minoarisoa Rajerison, Dawn N Birdsell
BACKGROUND: Genetic analysis of pathogenic organisms is a useful tool for linking human cases together and/or to potential environmental sources. The resulting data can also provide information on evolutionary patterns within a targeted species and phenotypic traits. However, the instruments often used to generate genotyping data, such as single nucleotide polymorphisms (SNPs), can be expensive and sometimes require advanced technologies to implement. This places many genotyping tools out of reach for laboratories that do not specialize in genetic studies and/or lack the requisite financial and technological resources...
December 11, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29223157/self-organization-of-recombinant-membrane-porin-ompf-from-yersinia-pseudotuberculosis-in-aqueous-environments
#19
E V Sidorin, V A Khomenko, N Yu Kim, P S Dmitrenok, A M Stenkova, O D Novikova, T F Solov'eva
Recombinant porin OmpF (an integral protein of bacterial outer membrane) from Yersinia pseudotuberculosis was synthesized in Escherichia coli cells as inclusion bodies. By combining the methods of anion-exchange and gel filtration chromatographies, recombinant OmpF (rOmpF) was isolated as an individual protein in its denatured state, and its characteristic properties (molecular mass, N-terminal amino acid sequence, and hydrodynamic radius of the protein in 8 M urea solution) were determined. According to the data of gel filtration, dynamic light scattering, optical spectroscopy, and binding of the hydrophobic fluorescent probe 8-anilino-1-naphthalenesulfonic acid, the rOmpF is fully unfolded in 8 M urea and exists in random coil conformation...
November 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/29209121/fatal-gastrointestinal-histoplasmosis-15-years-after-orthotopic-liver-transplantation
#20
Nikita Agrawal, David Ej Jones, Jessica K Dyson, Tim Hoare, Sharon A Melmore, Stephanie Needham, Nick P Thompson
We report a case of ileo-colonic Histoplasmosis without apparent respiratory involvement in a patient who had previously undergone an orthotopic liver transplant (OLT) for primary biliary cholangitis 15 years earlier. The recipient lived in the United Kingdom, a non-endemic region for Histoplasmosis. However, she had previously lived in rural southern Africa prior to her OLT. The patient presented with iron deficiency anaemia, diarrhoea, abdominal pain and progressive weight loss. She reported no previous foreign travel, however, it later became known that following her OLT she had been on holiday to rural southern Africa...
November 21, 2017: World Journal of Gastroenterology: WJG
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