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https://www.readbyqxmd.com/read/29793112/3d-printed-membrane-as-an-alternative-to-amniotic-membrane-for-ocular-surface-conjunctival-defect-reconstruction-an-in-vitro-in-vivo-study
#1
Shima Dehghani, Morteza Rasoulianboroujeni, Hamed Ghasemi, Saeed Heidari Keshel, Zohreh Nozarian, Mohammad Naser Hashemian, Mehran Zarei-Ghanavati, Golshan Latifi, Reza Ghaffari, Zhanfeng Cui, Hua Ye, Lobat Tayebi
BACKGROUND: The aim of this study was to evaluate the surgical handling and clinical applicability of a specific 3D-printed membrane design fabricated using a gelatin, elastin and sodium hyaluronate blend for conjunctival reconstruction and compare it with amniotic membrane (AM), which is normally used in such surgeries. METHODS: 3D printing technique was employed to fabricate the membrane based on gradient design. Prior to printing, rheometry was employed to optimize the ink composition...
May 11, 2018: Biomaterials
https://www.readbyqxmd.com/read/29793002/rasch-analysis-suggested-that-items-from-the-template-for-intervention-description-and-replication-tidier-checklist-can-be-summed-to-create-a-score
#2
Tie P Yamato, Chris G Maher, Bruno T Saragiotto, Mark J Catley, Anne M Moseley
OBJECTIVE: The aim of this study was to construct and evaluate a summary score of reporting completeness based on the Template for Intervention Description and Replication (TIDieR). STUDY DESIGN AND SETTING: We included 200 reports published in 2013 randomly selected from the Physiotherapy Evidence Database (PEDro). We summed the scores for the 12 items for the intervention and control groups for each trial in order to create a summary score from 0 to 24. Rasch analysis was used to investigate the item hierarchy, category function and reliability of the TIDieR checklist and determine the extent to which the summary score can be considered an interval-level measure...
May 21, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29792998/bmi-and-gender-increase-risk-for-sacral-fractures-after-multilevel-instrumented-spinal-fusion-compared-to-bone-mineral-density-and-pelvic-parameters
#3
Stephan N Salzmann, Courtney Ortiz Miller, John A Carrino, Jingyan Yang, Jennifer Shue, Andrew A Sama, Frank P Cammisa, Federico P Girardi, Alexander P Hughes
BACKGROUND CONTEXT: Sacral fractures are a rare but potentially devastating complication. Long-fusion constructs including the sacrum that do not extend to the pelvis may result in sacral fractures. Besides established risk factors including gender, age and number of levels fused, body mass index (BMI), pelvic parameters and bone mineral density (BMD) have also been proposed as potential risk factors for postoperative sacral fractures. The literature supporting this, however, is limited...
May 21, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29792778/does-iron-supplementation-improve-performance-in-iron-deficient-nonanemic-athletes
#4
Amity Rubeor, Carmen Goojha, Jeffrey Manning, Jordan White
CONTEXT: Supplementing iron-deficient nonanemic (IDNA) athletes with iron to improve performance is a trend in endurance sports. OBJECTIVES: To investigate the benefits of iron on performance, identify a ferritin level cutoff in IDNA athletes, and determine which iron supplementation regimens are most effective. DATA SOURCES: A search of the PubMed, CINAHL, Embase, ERIC, and Cochrane databases was performed in 2014 including all articles. Citations of pertinent review articles were also searched...
May 1, 2018: Sports Health
https://www.readbyqxmd.com/read/29792776/prevalence-of-inadequate-immunity-to-measles-mumps-rubella-and-varicella-in-mlb-and-nba-athletes
#5
Justin J Conway, Brett G Toresdahl, Daphne I Ling, Nicole T Boniquit, Lisa R Callahan, James J Kinderknecht
BACKGROUND: Multiple outbreaks of vaccine-preventable viral diseases have occurred in professional sports in recent years. Currently, there is no established protocol for vaccination or immunity screening for professional athletes. HYPOTHESIS: There are significant differences in the prevalence of inadequate immunity dependent on age, sport, country of birth, and participation in collegiate sports. STUDY DESIGN: Cross-sectional cohort study...
May 1, 2018: Sports Health
https://www.readbyqxmd.com/read/29792529/mir-155-accelerates-proliferation-of-mouse-hepatocytes-during-liver-regeneration-by-directly-targeting-socs1
#6
Xia Lin, Li Chen, Haiyan Li, Yu Liu, Yanhong Guan, Xiaoyan Li, Zhenchang Jia, Xiaolin Lin, Junshuang Jia, Yan Sun, Dong Xiao
Liver regeneration after 2/3 partial hepatectomy (PH) is a clinically significant repair process to restore proper liver architecture. Although microRNA-155 (miR-155) has been found to serve as a crucial microRNA (miRNA) regulator controlling liver cells functions and proliferation, little is known about its specific role in the regenerating liver. Using a mouse model with miR-155 overexpression or miR-155 knockout, we investigated the molecular mechanisms of miR-155 in liver regeneration. A marked induction of miR-155 was evident in C57BL/6 mice after PH...
May 24, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29792483/when-anger-expression-might-be-beneficial-for-african-americans-the-moderating-role-of-chronic-discrimination
#7
Jiyoung Park, Abdiel J Flores, Kirstin Aschbacher, Wendy Berry Mendes
OBJECTIVES: Anger expression is assumed to have mostly negative health effects. Yet, evidence is mixed on how anger expression influences African Americans' cardiovascular health. The present research aimed to clarify this link by examining moderating effects of chronic discrimination on the relationship between anger expression and cardiovascular risk among African Americans in experimental (Study 1) and epidemiological (Study 2) studies. METHOD: Study 1 examined how African Americans' trait anger expression was linked to (a) physiologic reactivity to acute social rejection during an interracial encounter (Session 1); and (b) total/HDL cholesterol assessed two months later (Session 2)...
May 24, 2018: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29792244/affective-problems-and-decline-in-cognitive-state-in-older-adults-a-systematic-review-and-meta-analysis
#8
A John, U Patel, J Rusted, M Richards, D Gaysina
Evidence suggests that affective problems, such as depression and anxiety, increase risk for late-life dementia. However, the extent to which affective problems influence cognitive decline, even many years prior to clinical diagnosis of dementia, is not clear. The present study systematically reviews and synthesises the evidence for the association between affective problems and decline in cognitive state (i.e., decline in non-specific cognitive function) in older adults. An electronic search of PubMed, PsycInfo, Cochrane, and ScienceDirect was conducted to identify studies of the association between depression and anxiety separately and decline in cognitive state...
May 24, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29792105/risk-factors-for-groin-injury-and-symptoms-in-elite-level-soccer-players-a-cohort-study-in-the-dutch-professional-leagues
#9
Rob Langhout, Igor Tak, Anne-Marie van Beijsterveldt, Martijn Ricken, Adam Weir, Maarten Barendrecht, Gino Kerkhoffs, Janine Stubbe
Study Design Cohort study with prospective and retrospective elements. Background Groin injury and symptoms are common in soccer players. Their relationship with reduced hip range of motion (ROM) and previous injury is unclear. Objectives To conduct a retrospective assessment of associations between previous injury and pre-season hip ROM and pre-season prevalence of severe groin symptoms; and prospective identification of risk factors for within-season groin injury. Methods During 2015-2016, 190 players from 9 Dutch professional soccer clubs participated...
May 23, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29792083/a-systematic-review-and-meta-analysis-of-the-association-between-vitamin-a-intake-serum-vitamin-a-and-risk-of-liver-cancer
#10
Nattawut Leelakanok, Ronilda R D'Cunha, Grerk Sutamtewagul, Marin L Schweizer
BACKGROUND: Previous evidence supports that vitamin A decreases the risk of several types of cancer. However, the association between vitamin A and liver cancer is inconclusive. AIM: This systematic review and meta-analysis summarizes the existing literature, discussing the association between vitamin A intake, serum vitamin A, and liver cancer in adult populations. METHODS: A systematic literature review was performed by searching the EMBASE, PubMed, Scopus and International Pharmaceutical Abstract databases using terms related to vitamin A (e...
January 1, 2018: Nutrition and Health
https://www.readbyqxmd.com/read/29792070/chondral-delamination-of-fresh-osteochondral-allografts-after-implantation-in-the-knee-a-matched-cohort-analysis
#11
Ryan C Rauck, Dean Wang, Matthew Tao, Riley J Williams
Introduction Delamination of the chondral surface of an osteochondral allograft (OCA) from the underlying cancellous bone has been described as a mode of failure after implantation in the knee. Our hypothesis was that increased storage time of the OCA is associated with increased risk of graft delamination after implantation. Methods Prospective data on 13 patients with evidence of OCA delamination identified on magnetic resonance imaging or during subsequent surgery from 2000 to 2015 were reviewed. A cohort of 33 patients without evidence of graft delamination were then matched to the delamination group based on recipient age, sex, body mass index (BMI), and chondral defect location...
May 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29792049/five-year-suicidal-ideation-trajectories-among-women-receiving-or-being-denied-an-abortion
#12
M Antonia Biggs, Heather Gould, Rana E Barar, Diana G Foster
OBJECTIVE: The aim of this study was to assess the effects of receiving compared with being denied an abortion on women's experiences of suicidal ideation over 5 years. METHOD: The authors recruited 956 women from 30 U.S. abortion facilities. Women were interviewed by telephone 1 week after their abortion visit, then every 6 months for 5 years. Women who received near-limit abortions were compared with women who were denied an abortion and carried their pregnancies to term (turnaway-birth group)...
May 24, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29791926/meniscus-repair-in-children-and-adolescents-a-systematic-review-of-treatment-approaches-meniscal-healing-and-outcomes
#13
Márcio Balbinotti Ferrari, Colin P Murphy, João Luiz Ellera Gomes
Although the consequences of traumatic meniscus tears and the importance of meniscal repair are well-established in adults, the same cannot be said for the young population. Better evidence regarding the outcomes following traumatic meniscal tears in children would improve our understanding of this increasing pathology and help define important factors in deciding the best treatment option. A systematic review was performed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines using the Cochrane Database of Systematic Review, Cochrane Central Register of Controlled Trials, MEDLINE Ovid, and MEDLINE PubMed databases...
May 23, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29791703/biological-intercalary-reconstruction-with-bone-grafts-after-joint-sparing-resection-of-the-lower-limb-is-this-an-effective-and-durable-solution-for-joint-preservation
#14
Francesco Muratori, Francesca Totti, Antonio D'Arienzo, Maurizio Scorianz, Guido Scoccianti, Giovanni Beltrami, Francesco Rosario Campo, Carmine Citarelli, Rodolfo Capanna, Domenico Andrea Campanacci
Due to advances in neoadjuvant therapies and preoperative imaging modalities, joint-sparing resections have become appealing in bone tumor surgery. However, the intercalary reconstruction of metadiaphyseal bone defects of the femur and the tibia after juxta-articular tumor resection remains challenging. Both biological and prosthetic reconstructions have been used for joint-sparing resections, but little is known about the long-term outcome of these procedures. The authors reviewed a consecutive series of 64 patients treated with joint-sparing intercalary resection and reconstruction with bone grafts...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29791596/treatment-with-ilex-paraguariensis-yerba-mate-aqueous-solution-prevents-hepatic-redox-imbalance-elevated-triglycerides-and-microsteatosis-in-overweight-adult-rats-that-were-precociously-weaned
#15
E de Oliveira, N S Lima, E P S Conceição, N Peixoto-Silva, E G Moura, P C Lisboa
Early weaning (EW) leads to overweight, visceral obesity, hyperleptinemia, and insulin resistance in adulthood. Treatment with Ilex paraguariensis (yerba mate) improves obesity and insulin resistance in these animals. Here, we evaluated the effects of chronic treatment with yerba mate on the redox balance and liver morphology of overweight early-weaned rats. To induce EW, we wrapped the dams with bandages to interrupt milk access during the last 3 days of lactation. Control pups (C) had free access to maternal milk for the full 21 days of lactation...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29791183/a-2-year-prospective-cohort-study-of-overuse-running-injuries-the-runners-and-injury-longitudinal-study-trails
#16
Stephen P Messier, David F Martin, Shannon L Mihalko, Edward Ip, Paul DeVita, D Wayne Cannon, Monica Love, Danielle Beringer, Santiago Saldana, Rebecca E Fellin, Joseph F Seay
BACKGROUND: The National Center for Injury Prevention and Control, noting flaws in previous running injury research, called for more rigorous prospective designs and comprehensive analyses to define the origin of running injuries. PURPOSE: To determine the risk factors that differentiate recreational runners who remain uninjured from those diagnosed with an overuse running injury during a 2-year observational period. STUDY DESIGN: Cohort study; Level of evidence, 2...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29791178/-rare-combination-of-turner-syndrome-and-congenital-adrenal-hyperplasia-with-21-hydroxylase-deficiency-case-report
#17
Ivana Ságová, Matej Stančík, Dušan Pavai, Daniela Kantárová, Anton Vaňuga, Peter Vaňuga
Combination of Turner syndrome (TS) and classic congenital adrenal hyperplasia (CAH) is rare. Globally, the incidence of CAH, autosomal recessive disorder caused by enzyme defect of steroidogenic pathway, is very low (1 : 10 000-16 000). 90 % of CAH cases are caused by 21-hydroxylase gene mutation (CYP21A2). Globally, the incidencie of Turner syndrome reaches 1 : 2 500. Phenotypically, females with TS may render wide spectrum of clinical features. Dominant symptoms are lowered terminal height and gonadal dysgenesia, ultimately leading to absence of puberty and infertility...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29790998/association-of-smokeless-tobacco-use-and-oral-cancer-a-systematic-global-review-and-meta-analysis
#18
Smita Asthana, Satyanarayana Labani, Uma Kailash, Dhirendra N Sinha, Ravi Mehrotra
Introduction: Smokeless tobacco products have been linked to precancerous and cancers of oral cavity for long. Evidence was available on the association between smokeless tobacco (SLT) products and oral cancers at regional but not at global level. Present meta-analysis is aimed to evaluate the risk of oral cancer with the use of SLT products among "ever" versus "never" users. Method: Studies published for the period (1960-2016) are retrieved using Pubmed, Indmed, EMBASE, and Google Scholar search engines for the subject "ever" versus "never" users of SLT products and estimated the risk association with oral cancer...
May 22, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29790929/mir172-downregulates-the-translation-of-cleistogamy-1-in-barley
#19
Nadia Anwar, Masaru Ohta, Takayuki Yazawa, Yutaka Sato, Chao Li, Akemi Tagiri, Mari Sakuma, Thomas Nussbaumer, Phil Bregitzer, Mohammad Pourkheirandish, Jianzhong Wu, Takao Komatsuda
Background and Aims: Floret opening in barley is induced by the swelling of the lodicule, a trait under the control of the cleistogamy1 (cly1) gene. The product of cly1 is a member of the APETALA2 (AP2) transcription factor family, which inhibits lodicule development. A sequence polymorphism at the miR172 target site within cly1 has been associated with variation in lodicule development and hence with the cleistogamous phenotype. It was unclear whether miR172 actually functions in cly1 regulation and, if it does, which miR172 gene contributes to cleistogamy...
May 22, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29790908/grass-legume-mixtures-sustain-strong-yield-advantage-over-monocultures-under-cool-maritime-growing-conditions-over-a-period-of-5-years
#20
Áslaug Helgadóttir, Matthias Suter, Thórey Ó Gylfadóttir, Thórdís A Kristjánsdóttir, Andreas Lüscher
Background and Aims: Grassland-based livestock systems in cool maritime regions are commonly dominated by grass monocultures receiving relatively high levels of fertilizer. The current study investigated whether grass-legume mixtures can improve the productivity, resource efficiency and robustness of yield persistence of cultivated grassland under extreme growing conditions over a period of 5 years. Methods: Monocultures and mixtures of two grasses (Phleum pratense and Festuca pratensis) and two legumes (Trifolium pratense and Trifolium repens), one of which was fast establishing and the other temporally persistent, were sown in a field trial...
May 22, 2018: Annals of Botany
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