Read by QxMD icon Read


Zhou Hong, Juan Li, Sangita Biswas, Cheng-Shuai Jiang, Yu Huang, Tao Sun, Yang Niu, Jian-Qiang Yu, Wei-Qi Li, Yao Yao
Tamarix ramosissima is a traditional Chinese herbal medicine used for rheumatoid arthritis (RA) treatment in Northwest China. Chemical investigation of EtOH/H2O extracts of T. ramosissima led to the discovery of a new flavonol, ramosissimin (1), together with the known flavonoids compounds quercetin (2), quercetin-3'4'-dimethylether (3) and kaempferol (4). By means of high resolution electrospray ionization mass spectroscopy (HRESIMS) and 1D and 2D-NMR experiments, and after comparison with literature data, the structures of the compounds were determined...
March 5, 2018: Die Pharmazie
Mohammad Ibrahim, Musadiq Ibrahim, Niaz Muhammad, Muhammad Ishaq Ali Shah, Gerlânia de Oliveira Leite, Joao B T Rocha
Selenium (Se) is a dietary essential trace element with important biological roles. It is a nutrient related to the complex metabolic and enzymatic functions. Organoselenium compounds have been reported to have anti-ulcer activity and used as drug for the treatment of gastrointestinal disorders. The antiulcer activity of binapthyl diselenide (NapSe)2 was investigated in ethanol-induced gastric lesions in rats. A number of markers of oxidative stress were examined in rats stomach including thiobarbituric acid reactive species (TBARS), catalase (CAT), superoxide dismutase (SOD), non-protein thiol groups (NPSH) and ascorbic acid...
March 13, 2018: Inflammopharmacology
Sae Bom Won, Young Hye Kwon
Offspring of female rats fed either a casein (CAS) diet or a low-isoflavone soy protein isolate (SPI) diet were compared in an animal model of chronic ethanol consumption to investigate whether maternal diet regulates the adaptive responses of offspring to postnatal ethanol exposure and potentially affects the development of liver disease in later life. Female rats were fed either a CAS or an SPI diet before mating, and during pregnancy and lactation. Male offspring from the same litter were pair-fed either a control or ethanol diet for six weeks (CAS/CON, CAS/EtOH, SPI/CON, and SPI/EtOH groups)...
March 10, 2018: Nutrients
N Khodaie, N Tajuddin, R M Mitchell, E J Neafsey, M A Collins
Preconditioning brain cultures with moderate concentrations of ethanol (EtOH) or trans-resveratrol (RES), key red wine constituents, can prevent amyloid-β (Aβ) neurotoxicity. Past studies have indicated that moderate EtOH activates synaptic N-methyl-D-aspartate receptors (NMDAR) that, in part, signal via protein kinase C (PKC) to increase protective antioxidant proteins such as peroxiredoxin-2 (Prx2). RES preconditioning also is reported to involve NMDAR and PKC. However, although moderate, the EtOH and RES concentrations used have been noticeably above circulating levels from two glasses of wine, a daily intake linked to reduced risk of cognitive decline among older social drinkers...
March 12, 2018: Neurotoxicity Research
Seungjun Lee, Dong-Cheol Kim, Hum Young Baek, Kyung-Dong Lee, Youn-Chul Kim, Hyuncheol Oh
This study was conducted to isolate the anti-neuroinflammatory component(s) in the 80% EtOH extract of P. tinctoria, and to investigate underlying molecular mechanism of the anti-neuroinflammatory component(s) in LPS-induced BV2 microglial cells. To isolate the active component(s) in the extract, various chromatographic methods were employed, and the structures of the isolated secondary metabolites were determined mainly by analysis of spectroscopic data such as NMR and MS data. Tryptanthrin (1), isolated from P...
March 12, 2018: Archives of Pharmacal Research
Fotios Tsopelas, Dimitris Konstantopoulos, Anna Tsantili Kakoulidou
In the present work, two approaches for the voltammetric fingerprinting of oils and their combination with chemometrics were investigated in order to detect the adulteration of extra virgin olive oil with olive pomace oil as well as the most common seed oils, namely sunflower, soybean and corn oil. In particular, cyclic voltammograms of diluted extra virgin olive oils, regular (pure) olive oils (blends of refined olive oils with virgin olive oils), olive pomace oils and seed oils in presence of dichloromethane and 0...
July 26, 2018: Analytica Chimica Acta
Hasan Kırmızıbekmez, Yiğit İnan, Rengin Reis, Hande Sipahi, Ahmet C Gören, Erdem Yeşilada
Phytochemical investigations on the EtOH extract of Clematis viticella led to the isolation of six flavonoid glycosides, isoorientin (1), isoorientin 3'-O-methyl ether (2), quercetin 7-O-α-L-rhamnopyranoside (3), quercetin 3,7-di-O-α-L-rhamnopyranoside (4), manghaslin (5) and chrysoeriol 7-O-β-D-glucopyranoside (6), one phenylethanol derivative, hydroxytyrosol (7), along with three phenolic acids, caffeic acid (8), (E)-p-coumaric acid (9) and p-hydroxybenzoic acid (10). The structures of the isolates were elucidated on the basis of NMR and HR-MS data...
March 12, 2018: Natural Product Research
Na Li, Deli Lu, Jinlong Zhang, Lingzhi Wang
Yolk-shell structured C@Li4 Ti5 O12 microspheres composed of carbon core (ca. 500 nm) and sea urchin-like Li4 Ti5 O12 shell (ca. 400-500 nm) are formed by hydrothermally treating the core-shell structured C@TiO2 in the EtOH/H2 O solution of LiOH and calcining it in N2 atmosphere. Yolk-shell structured TiO2 -type lithium ion sieve is further transformed from C@Li4 Ti5 O12 through the acid treatment, which have a high specific surface area of 201.74 m2 /g. The composite shows adsorption capacity towards Li+ proportional to the pH value in the range of 7-13...
February 10, 2018: Journal of Colloid and Interface Science
Thomas Braun, Claudia Berg, Nils Pfister, Beatrice Braun-Cula
The complex trans-[Pt(F)(SF3)(PCy3)2] shows a diverse reactivity pattern at the SF3 ligand towards ethanol and Me3SiOEt. This led by deoxyfluorination or alcoholysis to the generation of platinum complexes bearing a metal-bound S(O)F or S(OEt)2 group. For the latter reaction trans-[Pt(F){S(F)(OEt)2}(PCy3)2] is suggested as an intermediate. In reactivity studies of trans-[Pt(F)(SF2)(PCy3)2][BF4] the complex [Pt(F){S(F)(OEt)}(PCy3)2][BF4] was prepared, which does not react with ethanol.
March 10, 2018: Chemistry: a European Journal
Ramadan Ahmed Mekheimer, Mariam Abdullah Al-Sheikh, Hanadi Yousef Medrasi, Najla Hosain Hassan Alsofyani
A convenient, fast and environmentally benign procedure for the synthesis of a new series of highly functionalized N -alkylated pyridines as privileged medicinal scaffolds was developed via a unique three-component reaction of easily available aromatic as well as heteroaromatic aldehydes, N -alkyl-2-cyanoacetamides and malononitrile in EtOH in the presence of K₂CO₃ as a base promoter under microwave irradiation. The presented tandem process is presumed to proceed via Knoevenagel condensation, Michael addition, intramolecular cyclization, autoxidation and subsequent aromatization...
March 9, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Anthony Kopatsis, Christine Wagner, Helen Costello, Nicholas Morin, Katherine Elizabeth Kopatsis, Mario Gomez
We sought to determine patterns of injury in our Latino trauma community targeting alcohol (EtOH) intoxication as an influential variable. With the information gained in our culturally specific and culturally sensitive trauma community, we can use the information to fine-tune our trauma preventive medicine programs. Trauma injuries are the third largest contributor to racial disparities in the United States. Alcohol is involved in approximately half of all trauma admissions to trauma centers around the country...
March 2018: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
Yulei Wang, Zhidao Huang, Xuebing Leng, Huping Zhu, Guixia Liu, Zheng Huang
The first general catalytic approach to effecting transfer hydrogenation (TH) of unactivated alkenes using ethanol as the hydrogen source is described. A new NCP-type pincer iridium complex (BQ- NCO P)IrHCl containing a rigid benzoquinoline backbone has been developed for efficient, mild TH of unactivated C-C multiple bonds with ethanol, forming ethyl acetate as the sole byproduct. A wide variety of alkenes, including multisubstituted alkyl alkenes, aryl alkenes, and heteroatom-substituted alkenes, as well as O- or N-containing heteroarenes and internal alkynes, are suitable substrates...
March 8, 2018: Journal of the American Chemical Society
Anton D Kovalenko, Ivan S Bushmarinov, Anatolii S Burlov, Leonid S Lepnev, Elena G Ilina, Valentina V Utochnikova
Depending on the local excess of lanthanide ions (Ln = Lu, Yb, Er, Dy, Tb, Gd, Eu, Nd) or 2-(tosylamino)-benzylidene-N-benzoylhydrazone (H2 L), lanthanide complexes, containing either a mono-deprotonated ligand (Ln(HL)2 X, X = Cl, NO3 ) or both mono- and dideprotonated ligands (Ln(L)(HL)), were preparatively obtained. The crystal structures of Lu(HL)2 Cl, Yb(L)(HL)(H2 O)2 , Yb(L)(HL)(EtOH)2 (H2 O) and Er(L)(HL), determined by single crystal diffraction data or from powder diffraction data using Rietveld refinement, have shown the surprising resemblance...
March 6, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Stavroula I Sampani, Sidonie Aubert, Martin Cattoen, Kieran Griffiths, Alaa Abdul-Sada, Geoffrey R Akien, Graham J Tizzard, Simon J Coles, Stellios Arseniyadis, George E Kostakis
Four Zn/4f polynuclear coordination clusters (PCCs) formulated as [ZnDyL2 (CO3 )2 (NO3 )2 ] (1), [ZnII YIII L(NO3 )2 (o-van) (MeOH)] (MeOH) [2 (MeOH)] and [ZnII LnIII L(NO3 )2 Cl(EtOH)] where Ln is Dy (3) and Y (4) and where H2 L is the dinucleating Schiff base ligand N,N'-bis(3-methoxysalicylidene)cyclohexane-1,2-diamine and o-van is ortho-vanillin, were prepared and fully characterised for the first time. These air-stable heterometallic PCCs, obtained in high yields from commercially available materials, were shown to remain stable in solution in their dinuclear [ZnII LnIII L] form...
March 5, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Luciana da Silva Amaral, Edson Rodrigues-Filho, Christian P Kubicek, Christoph Herwig, Martina Marchetti-Deschmann, Günter Allmaier
RATIONALE: Although the fruiting-body of fungi of the genus Xylaria shows a great variety of morphological characteristics, their mycelial form are always very similar, imposing difficulties for their identification. Intact cell mass spectrometry (ICMS) using MALDI TOF MS can be a fast and reliable strategy to support the differentiation/identification of Xylaria species in those cases where fruit-bodies are not available. METHODS: Many experimental parameters such as sample preparation and culture media are crucial for filamentous fungi analysis by MALDI TOF MS...
March 2, 2018: Rapid Communications in Mass Spectrometry: RCM
S Sarshar, J Sendker, X Qin, F M Goycoolea, M R Asadi Karam, M Habibi, S Bouzari, U Dobrindt, A Hensel
Fruits from Apium graveolens (Celery) are used traditionally in Persian and European medicine for the treatment of uncomplicated urinary tract infections. No data are available on A. graveolens extract on the interplay between uropathogenic E. coli and the eukaryotic host cells and on quorum sensing of the bacteria. The present study aimed to characterize an antiadhesive and anti quorum sensing effect of a characterized A. graveolens extract by specific in vitro assays and to correlate these effects with in vivo data obtained by an animal infection model...
February 26, 2018: Fitoterapia
Gui-Jie Zhang, Lu-Mei Dai, Bin Zhang, Yong-Li Zhang, Heng-Shan Wang, Dong Liang
Ten compounds were isolated from the 95% aqueous EtOH extract of Clerodendrum bungei by a combination of various chromatographic techniques including column chromatography over silica gel, Sephadex LH-20, MCI, ODS, and semi-preparative HPLC. Their structures were elucidated as 11,12,16S-trihydroxy-7-oxo-17(15→16),18(4→3)-diabeo-abieta-3,8,11,13-tetraen-18-oic acid (1), 12S*,13R*-dihydroxy-9-oxo-octadeca-10(E)-enoic acid (2), clerodenoside A (3), trichotomoside (4), glycosmisic acid (5), 4'-O-methylscutellarein (6), neroplomacrol (7), butylitaconic acid (8), hexylitaconic acid (9), p-hydroxybenzonic acid (10) by their physicochemical properties and spectroscopic data...
December 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Wei Xu, Ya-Nan Ren, Miao Xie, Lin-Xia Zhou, Yue-Qing Zheng
A new series of uranium coordination polymers have been hydrothermally synthesized by using 1,4-naphthalene dicarboxylic acid (H2 NDC), namely, (H3 O)2 [(UO2 )2 (NDC)3 ]·H2 O (1), (H2 -bpp)[(UO2 )2 (NDC)3 ]·EtOH·5H2 O (2), (H2 -bpe)2/2 [(UO2 )2 (NDC)3 ]·EtOH (3), (H2 -bpp)[(UO2 )2 (NDC)3 ]·5H2 O (4), (H2 -bpp)[(UO2 )(HNDC)(NDC)]2 ·2H2 O (5), and (H2 -bpy)[(UO2 )(NDC)2 ] (6) [bpp = 1,3-di(4-pyridyl) propane, bpe = 4,4'-vinylenedipyridine, bpy = 4,4'-bipyridine]. Single-crystal X-ray diffraction demonstrates that complex 1 represents the uranyl-organic polycatenated framework derived from a simple two-dimensional honeycomb grid network structure via a H2 NDC linker...
February 27, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Marília M Wallauer, Fernanda Huf, Lucas S Tortorelli, Francine L Rahmeier, Fabiano B Carvalho, Rosalva T Meurer, Marilda da Cruz Fernandes
The link between Ethanol (EtOH) and tobacco (TOB) has potentially important implications for people involved in alcohol treatment; many alcoholics smoke, putting them at high risk of tobacco-related complications. The present study investigates the effect of chronic exposure to cigarette smoke, EtOH consumption and the combination of both on astrogliosis and apoptosis in the cerebellum of rats. Adult male Wistar rats were divided into 4 groups (8 animals per group): vehicle (glucose 3%, 10 mL/kg, twice a day), EtOH treated (EtOH 2 g/kg, twice a day), exposure to cigarette smoke (TOB, smoke of 6 cigarettes, twice a day) and a combination of EtOH and cigarette smoke (TOB + EtOH, twice a day)...
February 22, 2018: Neuroscience Letters
Md Rashedunnabi Akanda, In-Shik Kim, Dongchoon Ahn, Hyun-Jin Tae, Hyeon-Hwa Nam, Byung-Kil Choo, Kyunghwa Kim, Byung-Yong Park
Globally, gastric ulcer is a vital health hazard for a human. Rabdosia inflexa (RI) has been used in traditional medicine for inflammatory diseases. The present study aimed to investigate the protective effect and related molecular mechanism of RI using lipopolysaccharide (LPS)-induced inflammation in RAW 246.7 cells and HCl/EtOH-induced gastric ulcer in mice. We applied 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), nitric oxide (NO), reactive oxygen species (ROS), histopathology, malondialdehyde (MDA), quantitative real-time polymerase chain reaction (qPCR), immunohistochemistry (IHC), and Western blot analyses to evaluate the protective role of RI...
February 16, 2018: International Journal of Molecular Sciences
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"