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https://www.readbyqxmd.com/read/29777092/seroprevalence-of-brucellosis-in-butchers-veterinarians-and-slaughterhouse-workers-in-hamadan-western-iran
#1
Mojgan Mamani, Mohammad Mehdi Majzoobi, Fariba Keramat, Nesa Varmaghani, Abbas Moghimbeigi
BACKGROUND: Brucellosis is a zoonotic disease caused by Brucella species via infected domestic animals. In endemic areas, certain occupations such as veterinarians, butchers, and slaughterhouse workers are considered high risk regarding brucellosis. We evaluated the seroprevalence of brucellosis in high-risk occupations in Hamadan, West of Iran. STUDY DESIGN: a cross-sectional study. METHODS: Overall, 218 participants from 2014 to 2015 were enrolled...
February 10, 2018: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/29774022/acute-zika-virus-infection-in-an-endemic-area-shows-modest-proinflammatory-systemic-immunoactivation-and-cytokine-symptom-associations
#2
Jéssica Barletto de Sousa Barros, Paulo Alex Neves da Silva, Rosemary de Carvalho Rocha Koga, Patrícia Gonzalez-Dias, José Rodrigues Carmo Filho, Patrícia Resende Alo Nagib, Verônica Coelho, Helder I Nakaya, Simone Gonçalves Fonseca, Irmtraut Araci Hoffmann Pfrimer
An early immune response to Zika virus (ZIKV) infection may determine its clinical manifestation and outcome, including neurological effects. However, low-grade and transient viremia limits the prompt diagnosis of acute ZIKV infection. We have investigated the plasma cytokine, chemokine, and growth factor profiles of 36 individuals from an endemic area displaying different symptoms such as exanthema, headache, myalgia, arthralgia, fever, hyperemia, swelling, itching, and nausea during early-phase infection...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29771193/early-symptoms-of-systemic-lupus-erythematosus-sle-recalled-by-339-sle-patients
#3
N Leuchten, B Milke, B Winkler-Rohlfing, D Daikh, T Dörner, S R Johnson, M Aringer
Objective The European League Against Rheumatism and the American College of Rheumatology jointly embarked on a new classification criteria for systemic lupus erythematosus (SLE) project. Its first phase involved generation of a broad set of items potentially useful for classification of SLE. This study was undertaken to add the patient perspective to an expert Delphi approach and an early patient cohort study. Methods A national cross-sectional study was conducted. A self-report questionnaire was published in the "Schmetterling" (Butterfly), the quarterly journal of the German SLE patient association...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29768412/adverse-events-following-single-dose-treatment-of-lymphatic-filariasis-observations-from-a-review-of-the-literature
#4
Philip J Budge, Carly Herbert, Britt Andersen, Gary J Weil
BACKGROUND: WHO's Global Programme to Eliminate Lymphatic Filariasis (LF) uses mass drug administration (MDA) of anthelmintic medications to interrupt LF transmission in endemic areas. Recently, a single dose combination of ivermectin (IVM), diethylcarbamazine (DEC), and albendazole (ALB) was shown to be markedly more effective than the standard two-drug regimens (DEC or IVM, plus ALB) for achieving long-term clearance of microfilaremia. OBJECTIVE AND METHODS: To provide context for the results of a large-scale, international safety trial of MDA using triple drug therapy, we searched Ovid Medline for studies published from 1985-2017 that reported adverse events (AEs) following treatment of LF with IVM, DEC, ALB, or any combination of these medications...
May 16, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29767650/immediate-effect-of-continuous-ultrasound-vs-sham-ultrasound-for-bilateral-masseter-myalgia-a-double-blinded-trial
#5
Haseeb Hussain, Heidi Crow, Yoly Gonzalez, W D McCall
AIMS: To investigate the local and segmental effects of therapeutic ultrasound at a dose of 0.4 w/cm2 with 100% duty cycle for 5 minutes compared to the effect of sham ultrasound on painful masticatory muscles. METHODS: A total of 20 adult female subjects with bilateral masseter myalgia diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) were included. Each subject was randomized to either an active ultrasound group or a sham ultrasound group...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29764833/early-prosthetic-valve-endocarditis-after-transcatheter-aortic-valve-implantation-using-st-jude-medical-portico-valve
#6
Abdalla Ibrahim, Aneeq Ahmed, Thomas Kiernan, Samer Arnous
An 87-year-old woman presented to the emergency department with a 2-week history of progressively worsening shortness of breath, fever and generalised myalgia. She underwent a transcatheter Portico aortic valve implantation for severe symptomatic aortic stenosis 3 months prior to this presentation. Examination revealed a temperature of 40°C and a systolic murmur in the aortic area. Inflammatory markers were elevated, and blood cultures were positive for methicillin-sensitive Staphylococcus aureus A possible diagnosis of infective endocarditis was made as one major and one minor criterion in the modified Duke criteria were fulfilled...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29757803/fever-and-debilitating-myalgia
#7
Eun Young Ahn, Jin Kyun Park
No abstract text is available yet for this article.
May 11, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29749052/exercise-testing-based-algorithms-to-diagnose-mcardle-disease-and-mad-defects
#8
J-B Noury, F Zagnoli, J-L Carré, I Drouillard, F Petit, C Le Maréchal, P Marcorelles, F Rannou
OBJECTIVE: As exercise intolerance and exercise-induced myalgia are commonly encountered in metabolic myopathies, functional screening tests are commonly used during the diagnostic work-up. Our objective was to evaluate the accuracy of isometric handgrip test (IHT) and progressive cycle ergometer test (PCET) to identify McArdle disease and myoadenylate deaminase (MAD) deficiency and to propose diagnostic algorithms using exercise-induced lactate and ammonia variations. METHODS: A prospective sample of 46 patients underwent an IHT and a PCET as part of their exercise-induced myalgia and intolerance evaluation...
May 10, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29745339/musculoskeletal-and-rheumatic-diseases-induced-by-immune-checkpoint-inhibitors-a-review-of-the-literature
#9
Devis Benfaremo, Lucia Manfredi, Michele Maria Luchetti, Armando Gabrielli
BACKGROUND: Immune checkpoint inhibitors are a new promising class of antitumor drugs that have been associated to a number of immune-related adverse events (AEs), including musculoskeletal and rheumatic disease. METHODS: We searched Medline reviewing reports of musculoskeletal and rheumatic AEs induced by immune checkpoint inhibitors. RESULTS: Several musculoskeletal and rheumatic AEs associated with immune checkpoint inhibitors treatment are reported in literature...
May 8, 2018: Current Drug Safety
https://www.readbyqxmd.com/read/29744303/recurrent-rhabdomyolysis-caused-by-carnitine-palmitoyltransferase-ii-deficiency-common-but-under-recognised-lessons-to-be-learnt
#10
M Balasubramanian, T M Jenkins, R J Kirk, I M Nesbitt, S E Olpin, M Hill, G T Gillett
We discuss two adult siblings who presented with symptoms of myalgia and rhabdomyolysis following exercise with myoglobinuria; genetic testing confirmed carnitine palmitoyltransferase II deficiency and resulted in institution of appropriate crisis management and dietary advice. We explore the phenotypic variability of this commonest fatty oxidation defect that remains under-diagnosed in the adult population and provide clues for early recognition and diagnosis.
June 2018: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/29742693/a-successful-treatment-of-severe-systemic-lupus-erythematosus-caused-by-occult-pulmonary-infection-associated-with-hemophagocytic-syndrome-a-case-report
#11
Weihong Shi, Mingyang Duan, Ligang Jie, Weifeng Sun
RATIONALE: A 27-year-old woman with a history of systemic lupus erythaematosus (SLE) developed hemophagocytic syndrome (HPS) secondary due to an unrecognized infection that led to severe SLE with a prolonged recovery. PATIENT CONCERNS: The patient showed a high spiking fever and myalgia. Laboratory data revealed pancytopenia and immunological abnormalities. Pulse methylprednisone plus intravenous immunoglobulin (IVIG) failed to improve the clinical symptoms and laboratory data...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29742055/musculoskeletal-manifestations-in-hereditary-periodic-fever-syndromes
#12
REVIEW
Martina Soliani, Marco Cattalini, Antonio Vitale, Jurgen Sota, Luca Cantarini
Monogenic autoinflammatory diseases (AIDs) are a group of inflammatory disorders induced by deregulation of the innate immune system and characterised by inflammatory bouts with fever as well as a large spectrum of other possible manifestations involving most organs and tissues. In this context, musculoskeletal manifestations represent a frequent finding in the clinical picture of patients with AIDs and may range from less severe affections including myalgia and arthralgia to severe arthritis, muscle fasciitis, bone erosions, and joint deformities...
January 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29739801/statin-use-and-adverse-effects-among-adults-75-years-of-age-insights-from-the-patient-and-provider-assessment-of-lipid-management-palm-registry
#13
Michael G Nanna, Ann Marie Navar, Tracy Y Wang, Xiaojuan Mi, Salim S Virani, Michael J Louie, L Veronica Lee, Anne C Goldberg, Veronique L Roger, Jennifer Robinson, Eric D Peterson
BACKGROUND: Current statin use and symptoms among older adults in routine community practice have not been well characterized since the release of the 2013 American College of Cardiology/American Heart Association guideline. METHODS AND RESULTS: We compared statin use and dosing between adults >75 and ≤75 years old who were eligible for primary or secondary prevention statin use without considering guideline-recommended age criteria. The patients were treated at 138 US practices in the Patient and Provider Assessment of Lipid Management (PALM) registry in 2015...
May 8, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29737466/clinical-features-of-haff-disease-and-myositis-after-the-consumption-of-boiled-brackish-water-crayfish-a-retrospective-study-of-96-cases-at-a-single-centre
#14
Fei He, Jun Ni, Jun-Ai Huang, Yao Liu, Chao Wu, Jun Wang
The present study describes the difference in clinical features between the patients with Haff disease and crayfish-related myositis (CRM) after crayfish consumption. This was a single-centre, retrospective analysis at the Emergency Department of the Drum Tower Hospital of Nanjing University School of Medicine from July to August of 2016. The baseline information came from the Electronic Medical Record System at the institution. Totally 96 patients were included, of whom 52 patients were confirmed to have Haff disease and 44 patients were CRM...
May 8, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29735962/fatal-myopericarditis-following-an-influenza-a-h3n2-infection
#15
Caroline Lefeuvre, Sylvie Behillil, Stéphane Triau, Antonio Monteiro-Rodrigues, François Templier, Cong Tri Tran, Hélène Le Guillou-Guillemette, Françoise Lunel-Fabiani, Vincent Enouf, Alexandra Ducancelle
BACKGROUND Influenza viruses induce uncomplicated infections in most cases in individuals with no known predisposing factors. Acute febrile illness is generally limited to upper respiratory symptoms and several constitutional symptoms, including headache, lethargy, and myalgia. However, influenza A virus is a cause of severe morbidity and mortality worldwide. Some patients are at risk for serious and fatal complications. Cardiac involvement is a well-known condition, but, clinically apparent influenza myocarditis is not common...
May 8, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29734882/assessment-of-association-between-muscular-diagnosis-in-temporomandibular-disorders-with-mandibular-kinematics
#16
Miguel Maulén-Yáñez, Walther Meeder-Bella, Patricio Javier Videla-Jiménez, Wilfredo Alejandro González-Arriagada
Objective To study the association between mandibular kinematics and muscular diagnoses in temporomandibular disorders (TMD). Method Retrospective, descriptive clinical study based on an analysis of 370 clinical records of muscle diagnoses in TMD. Statistical analysis was performed with the SPSS program. Results Five different muscle diagnoses were considered. Myospasm and centrally mediated myalgia were discarded from the statistical analysis because of their low incidences. The diagnoses included in the analysis were protective co-contraction, myofascial pain, and myalgia...
May 7, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29731937/carnitine-palmitoyltransferase-ii-deficiency-cpt-ii-followed-by-rhabdomyolysis-and-acute-kidney-injury
#17
Nikola Gjorgjievski, Pavlina Dzekova-Vidimliski, Zvezdana Petronijevic, Gjulsen Selim, Petar Dejanov, Liljana Tozija, Aleksandar Sikole
BACKGROUND: Carnitine palmitoyltransferase II deficiency (CPT II) is an autosomal recessive disorder and the most common inherited disorder of mitochondrial long-chain fatty acid oxidation, characterised by attacks of myalgia and myoglobinuria. The most common "classic" myopathic form occurs in young adults and is characterised by recurrent episodes of rhabdomyolysis triggered by prolonged exercise, fasting or febrile illness. CASE PRESENTATION: We present a case of a 22-year-old Caucasian male admitted to our hospital with fever, dyspnea, fatigue, myalgia and dark urine (brown-coloured)...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29729202/non-hemorrhagic-joint-disorders-and-vitamin-k-antagonists-an-under-recognized-adverse-drug-reaction
#18
Johana Béné, Clémentine Rousselin, Haleh Bagheri, Thierry Vial, Sophie Gautier, Marc Lambert
Isolated arthralgia, without hemorrhagic side effect exists and is considered as a very rare adverse drug reaction according to vitamin K antagonists' (VKAs) summary of product characteristics. Up to now, there are no literature reports of isolated, non-hemorrhagic joint complications in patients receiving VKAs. Hence, the objective of this study was to describe cases of VKA-related non-hemorrhagic joint disorders (fluindione, warfarin, and acenocoumarol) reported in the French Pharmacovigilance Database (FPVD)...
May 5, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29727476/diagnostic-criteria-for-temporomandibular-disorders-diagnostic-accuracy-for-general-dentistry-procedure-without-mandatory-commands-regarding-myalgia-arthralgia-and-headache-attributed-to-temporomandibular-disorder
#19
Catharina Österlund, Hannes Berglund, Madeleine Åkerman, Evelina Nilsson, Hanna Petersson, Julia Lam, Per Alstergren
BACKGROUND: The clinical examination in Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) is a strict procedure and comprise mandatory commands. However, learning and using these mandatory commands in general practice have proven to be difficult and their use of DC/TMD is minimal. OBJECTIVES: To investigate if reliability on a diagnostic level for DC/TMD diagnoses differ between examiners using the mandatory commands or not. METHODS: Six examiners were divided into two groups: one using the mandatory commands in DC/TMD for the clinical examination and one that did not use the mandatory commands...
May 4, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29724267/demographic-clinical-and-laboratory-features-of-leptospirosis-and-dengue-co-infection-in-malaysia
#20
Munirah Hishamshah, Norazah Ahmad, Hishamshah Mohd Ibrahim, Nurul Atiqah Nur Halim, Salbiah Nawi, Fairuz Amran
PURPOSE: In this study, we aim to describe and compare the demographical, clinical and laboratory features of leptospirosis and dengue co-infections (LDCI) against single leptospirosis infections in Malaysia. METHODOLOGY: Data of patients admitted to various hospitals in Malaysia from 2011 to 2015 diagnosed with leptospirosis in our laboratory were obtained from their admission records. Co-infection with dengue was determined by collecting dengue serology results...
May 4, 2018: Journal of Medical Microbiology
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