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https://www.readbyqxmd.com/read/28734568/antibacterial-properties-of-nano-silver-coated-peek-prepared-through-magnetron-sputtering
#1
Xiuju Liu, Kang Gan, Hong Liu, Xiaoqing Song, Tianjie Chen, Chenchen Liu
OBJECTVE: We aimed to investigate the cytotoxicity and antibacterial properties of nano-silver-coated polyetheretherketone (PEEK) produced through magnetron sputtering and provide a theoretical basis for its use in clinical applications. METHODS: The surfaces of PEEKs were coated with nano-silver at varying thicknesses (3, 6, 9, and 12nm) through magnetron sputtering technology. The resulting coated PEEK samples were classified into the following groups according to the thickness of the nano-silver coating: PEEK-3 (3nm), PEEK-6 (6nm), PEEK-9 (9nm), PEEK-12 (12nm), and PEEK control group...
July 19, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28733529/immunotherapy-of-wap-tnp-mice-with-early-stage-mammary-gland-tumors
#2
Michael Bruns, Wolfgang Deppert
The SV40 transgenic BALB/c mouse based WAP-T/WAP-TNP model for triple-negative breast cancer allows the analysis of parameters influencing immunotherapeutic approaches. Except for WAP-TNP tumors expressing the immune-dominant LCMV NP-epitope within SV40 T-antigen (T-AgNP) which is not expressed by T-Ag of WAP-T tumors, the tumors are extremely similar. Comparative anti-PD1/PD-L1 immunotherapy of WAP-T and WAP-TNP mice supported the hypothesis that the immunogenicity of tumor antigen T-cell epitopes strongly influences the success of immune checkpoint blockade therapy, with highly immunogenic T-cell epitopes favoring rapid CTL exhaustion...
June 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732957/sonochemical-synthesis-of-silver-nanoparticles-anchored-reduced-graphene-oxide-nanosheets-for-selective-and-sensitive-detection-of-glutathione
#3
Victor Vinoth, Jerry J Wu, Abdullah M Asiri, Sambandam Anandan
Developed here an eco-friendly, one-pot approach toward rapid synthesis of silver nanoparticles anchored reduced graphene oxide (AgNPs(TMSPED)-rGO) nanosheets via sonochemical irradiation method, using an aqueous solution mixture of GO and AgNO3 in the presence of N-[3(trimethoxysilyl)propyl] ethylenediamine (TMSPED) without any reducing agent. As synthesized decorated nanosheets was thoroughly characterized by transmission electron microscopy (TEM), atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) spectroscopy, Raman spectroscopy and X-ray photoelectron spectroscopy (XPS)...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28731325/bioinspired-and-biomimetic-agnps-gentamicin-embedded-silk-fibroin-coatings-for-robust-antibacterial-and-osteogenetic-applications
#4
Wenhao Zhou, Zhaojun Jia, Pan Xiong, Jianglong Yan, Yangyang Li, Ming Li, Yan Cheng, Yufeng Zheng
With the progressively increasing demand for orthopedic Ti implants, the balance realization between two primary complications restricting implants applications is imperative needed to be solved that the lack of bone tissue integration and biomedical device-associated infections (BAI), where emergence of multi-resistance bacteria make it worse. Notably, a combination of silver nanoparticles (AgNPs) and a kind of antibiotic can synergistically inhibit bacterial growth, where low concentration of AgNPs has been confirmed to promote the proliferation and osteogenesis of osteoblasts...
July 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28730357/biosynthesis-of-silver-nanoparticles-from-spirulina-microalgae-and-its-antibacterial-activity
#5
Govarthanan Muthusamy, Selvankumar Thangasamy, Mythili Raja, Sudhakar Chinnappan, Selvam Kandasamy
The present work focuses on a low-cost, simple, and green synthesis of silver nanoparticles (AgNPs) by mixing AgNO3 solution with the extract of Spirulina platensis (SP) without any chemical reducing and/or capping agents. The green synthesis of AgNPs was confirmed by the color change from colorless to yellowish brown. The biosynthesis of AgNPs was further confirmed by UV-visible spectroscopy (UV-vis), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), biological transmission electron microscopy (Bio-TEM), and energy dispersive X-ray analysis (EDX)...
July 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28727146/antimicrobial-effects-of-silver-nanoparticles-synthesized-by-fatsia-japonica-leaf-extracts-for-preservation-of-citrus-fruits
#6
Jing Zhang, Guoguo Si, Jun Zou, Ruiliang Fan, Ailing Guo, Xuetuan Wei
Due to their potent antimicrobial activity, silver nanoparticles (AgNPs) synthesized by biomass might be promising in food preservation, whereas effects of AgNPs on Penicillium italicum-induced rot of Citrus fruits have not been investigated. In this study, a novel AgNPs biosynthesis method was developed based on Fatsia japonica leaf extracts. It was revealed that concentrations of leaf extracts, AgNO3 and NaCl affected AgNPs yields and particle sizes obviously. Under the optimized conditions (8 mg/mL extracts, 2 mM AgNO3 and 1 mM NaCl), AgNPs, synthesized within 80 min, showed potent preservative effect against P...
July 20, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28725884/an-enzyme-mediated-competitive-colorimetric-sensor-based-on-au-ag-bimetallic-nanoparticles-for-highly-sensitive-detection-of-disease-biomarkers
#7
Binfeng Yin, Wenshu Zheng, Mingling Dong, Wenbo Yu, Yiping Chen, Sang Woo Joo, Xingyu Jiang
We developed a competitive colorimetric nanosensor based on Au@Ag bimetallic nanoparticles for the detection of interleukin-6 (IL-6) in clinical samples. Antibody-conjugated magnetic nanoparticles (MNPs) and polystyrene (PS) microparticles conjugated with both catalase and a secondary antibody can form sandwich structures that enable one-step target enrichment and separation. The catalase on the surface of the PS can catalyze the hydrolysis of hydrogen peroxide (H2O2) to regulate the deposition of Ag(+) on the surface of gold nanoparticles (AuNPs), and forms different sizes and amounts of Au@Ag bimetallic nanoparticles (Au@AgNPs) which produce a distinct color signal for readout with the naked eye...
July 20, 2017: Analyst
https://www.readbyqxmd.com/read/28724260/pleuropterus-multiflorus-hasuo-mediated-straightforward-eco-friendly-synthesis-of-silver-gold-nanoparticles-and-evaluation-of-their-anti-cancer-activity-on-a549-lung-cancer-cell-line
#8
Verónica Castro-Aceituno, Ragavendran Abbai, Seong Soo Moon, Sungeun Ahn, Ramya Mathiyalagan, Yu-Jin Kim, Yeon-Ju Kim, Deok Chun Yang
Pleuropterus multiflorus (Hasuo) is a widely used medicinal plant in Korea and China for treating amnesia, isnomia, heart throbbing etc. With the constructive idea of promoting the wide-spread usage of P. multiflorus, we propose its indirect usage in the form of biologically active silver (Pm-AgNPs) and gold nanoparticles (Pm-AuNPs). The synthesized nanoparticles were predominantly spherical, crystalline with the Z-average hydrodynamic diameter of 274.8nm and 104.8nm respectively. Also, proteins and phenols were identified as the major players involved in their synthesis and stability...
July 15, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28722828/bioaccumulation-based-silver-nanoparticle-toxicity-in-daphnia-magna-and-maternal-impacts
#9
Sunandan Pakrashi, Cheng Tan, Wen-Xiong Wang
In this study, we tested whether the bioaccumulation in specific tissues of Daphnia magna could explain silver nanoparticles (AgNPs) toxicity. Daphnids were exposed to different concentrations of well suspended AgNPs and AgNO3 . The accumulations of Ag in the whole body, guts and non-gut tissues, as well as the mortality of daphnids were recorded over a period of 7 days. Regression analysis showed higher degree of positive correlation between the concentration of Ag in the non-gut tissues than gut tissues and the mortality of the daphnids...
July 19, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28722404/high-performance-colorimetric-detection-of-thiosulfate-by-using-silver-nanoparticles-for-smartphone-based-analysis
#10
Chen Dong, Zhuqing Wang, Yujie Zhang, Xuehua Ma, M Zubair Iqbal, Lijing Miao, Zhuangwei Zhou, Zheyu Shen, Aiguo Wu
Developing thiosulfate (S2O32-) sensors with silver nanoparticles (AgNPs) for analysis of aqueous solutions with the interference of other anions remains challenging. In this study, we propose a new strategy for excellent selective colorimetric detection of S2O32-. The non-morphological transition of AgNPs leading to a color change from yellow to brown is verified by UV-vis, TEM, DLS, SEM, and XPS analyses. The sensor exhibits high sensitivity with detection limits of 1.0 µM by naked-eye determination and 0...
July 19, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28721743/responses-of-human-hepatoma-hepg2-cells-to-silver-nanoparticles-and-polycyclic-aromatic-hydrocarbons
#11
Francisco Filipak Neto, Ludiana Cardoso da Silva, Samuel Liebel, Carmen Lúcia Voigt, Ciro Alberto de Oliveira Ribeiro
The nanotechnology has revolutionized the global market with silver nanoparticles (AgNP) occupying a prominent position due to their remarkable anti-bacterial properties. However, there is no data about the adverse and toxic effects of associations of AgNP and ubiquitous compounds, such as polycyclic aromatic hydrocarbons (PAH). In the current study, we investigated the responses of HepG2 cells to realistic concentrations of AgNP (0.09, 0.9 and 9 ng ml(-1)) and mixture of PAH (30 and 300 ng ml(-1)), separately and in association...
July 19, 2017: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28721573/exposure-to-silver-nanoparticles-affects-viability-and-function-of-natural-killer-cells-mostly-via-the-release-of-ions
#12
Loretta Müller, Selina K Steiner, Laura Rodriguez-Lorenzo, Alke Petri-Fink, Barbara Rothen-Rutishauser, Philipp Latzin
Natural killer (NK) cells play a crucial role in linking innate and adaptive immune responses, especially during viral infections and tumor surveillance. They have two major effector functions: the killing of stressed/abnormal cells and the release of cytokines. Their activity is regulated via inhibitory and activating surface receptors. At the same time that the production and use of engineered nanoparticles is steadily increasing, the risk for exposure to silver nanoparticles (AgNPs) from consumer products or biomedical applications is growing...
July 18, 2017: Cell Biology and Toxicology
https://www.readbyqxmd.com/read/28721025/antibacterial-effect-of-silver-nanoparticles-in-pseudomonas-aeruginosa
#13
R Salomoni, P Léo, A F Montemor, B G Rinaldi, Mfa Rodrigues
Pseudomonas aeruginosa has great intrinsic antimicrobial resistance limiting the number of effective antibiotics. Thus, other antimicrobial agents such as silver nanoparticles (AgNPs) are considered potential agents to help manage and prevent infections. AgNPs can be used in several applications against bacteria resistant to common antibiotics or even multi-resistant bacteria such as P. aeruginosa. This study assessed the antimicrobial activity of commercial 10 nm AgNPs on two hospital strains of P. aeruginosa resistant to a large number of antibiotics and a reference strain from a culture collection...
2017: Nanotechnology, Science and Applications
https://www.readbyqxmd.com/read/28720002/green-synthesis-of-silver-nanoparticles-using-prosopis-juliflora-bark-extract-reaction-optimization-antimicrobial-and-catalytic-activities
#14
Geeta Arya, R Mankamna Kumari, Nidhi Gupta, Ajeet Kumar, Ramesh Chandra, Surendra Nimesh
In the present study, silver nanoparticles (PJB-AgNPs) have been biosynthesized employing Prosopis juliflora bark extract. The biosynthesis of silver nanoparticles was monitored on UV-vis spectrophotometer. The size, charge and polydispersity index (PDI) of PJB-AgNPs were determined using dynamic light scattering (DLS). Different parameters dictating the size of PJB-AgNPs were explored. Nanoparticles biosynthesis optimization studies suggested efficient synthesis of highly dispersed PJB-AgNPs at 25 °C when 9...
July 18, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28719862/green-biosynthesis-of-silver-nanoparticles-using-leaves-extract-of-artemisia-vulgaris-and-their-potential-biomedical-applications
#15
Tahir Rasheed, Muhammad Bilal, Hafiz M N Iqbal, Chuanlong Li
Biosynthesis of nanoparticles from plant extracts is receiving enormous interest due to their abundant availability and a broad spectrum of bioactive reducing metabolites. In this study, the reducing potential of Artemisia vulgaris leaves extract (AVLE) was investigated for synthesizing silver nanoparticles without the addition of any external reducing or capping agent. The appearance of blackish brown color evidenced the complete synthesis of nanoparticles. The synthesized silver nanoparticles were characterized by UV-vis spectroscopy, scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX), transmission electron microscope (TEM), atomic force microscopy (AFM) and Fourier transforms infrared spectroscopy (FT-IR) analysis...
July 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28719861/stabilized-cationic-dipeptide-capped-gold-silver-nanohybrids-towards-enhanced-antibacterial-and-antifungal-efficacy
#16
Manish Bajaj, Satish K Pandey, Tamanna Nain, Surinder K Brar, Prabhjot Singh, Shivakanksha Singh, Nishima Wangoo, Rohit K Sharma
The nanoparticles of silver/gold and cationic peptides have been recognized as potent antimicrobials for long, but their combined effect has so far not been explored. The present study reports the green synthesis of short cationic dipeptide stabilized AuNPs/AgNPs based nanohybrid materials. It thoroughly investigates the effect of conjugation of short cationic peptides on the antimicrobial properties of metallic nanoparticles. In the context of the antimicrobial evaluation of synthesized nanoconjugates, it was observed that peptide capped AgNPs exhibited higher antimicrobial activity as compared to peptide capped AuNPs as well as native peptides and unconjugated metallic nanoparticles...
July 9, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28718777/an-assembly-and-interaction-of-upconversion-and-plasmonic-nanoparticles-on-organometallic-nanofibers-enhanced-multicolor-upconversion-downshifting-emission-and-plasmonic-effect
#17
Priyam Singh, Praveen Kumar Shahi, Rajiv Prakash, S B Rai
We herein present a novel inorganic-organic hybrid nanoparticle (HNPs) constituted of inorganic NPs, NaY0.78Er0.02Yb0.2F4, and organometallic nanofiber, Tb(ASA)3Phen (TAP). The X-ray diffraction, Fourier transform infrared absorption and TEM analyse reveal that, the prepared ultrafine upconversion nanoparticles {UCNPs (6-9 nm)} are dispersed on the surface of TAP nanofibers. We observe that addition of TAP in UCNPs, effectively prevents the surface quenching to boost the UC intensity and enables tuning of UC emission from green to red region by controlling the phonon frequency around Er3+ ion...
July 18, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28716969/genetic-determinants-of-susceptibility-to-silver-nanoparticle-induced-acute-lung-inflammation-in-mice
#18
David K Scoville, Dianne Botta, Karen Galdanes, Stefanie C Schmuck, Collin C White, Patricia L Stapleton, Theo K Bammler, James W MacDonald, William A Altemeier, Michelle Hernandez, Steven R Kleeberger, Lung-Chi Chen, Terry Gordon, Terrance J Kavanagh
Silver nanoparticles (AgNPs) are employed in a variety of consumer products; however, in vivo rodent studies indicate that AgNPs can cause lung inflammation and toxicity in a strain- and particle type-dependent manner, but mechanisms of susceptibility remain unclear. The aim of this study was to assess the variation in AgNP-induced lung inflammation and toxicity across multiple inbred mouse strains and to use genome-wide association (GWA) mapping to identify potential candidate susceptibility genes. Mice received doses of 0...
July 17, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28716752/anticancer-activity-of-silver-and-copper-embedded-chitin-nanocomposites-against-human-breast-cancer-mcf-7-cells
#19
Dhanasekaran Solairaj, Palanivel Rameshthangam, Gnanapragasam Arunachalam
Chitin is a natural biopolymer widely used in biomedical and environmental applications due to its distinctive physical, chemical and mechanical properties. Although the anticancer property of chitin nanoforms and chitin derivatives against various cancers were studied earlier, there is no report in the chitin nanostructure incorporated metal nanocomposite. The present study was aimed to investigate the cytotoxicity of chitin incorporated silver and copper nanocomposite against human breast cancer (MCF-7) cells...
July 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28715772/stability-of-single-dispersed-silver-nanoparticles-in-natural-and-synthetic-freshwaters-effects-of-dissolved-oxygen
#20
Xiaoyan Zou, Penghui Li, Jie Lou, Xiaoyan Fu, Hongwu Zhang
Silver nanoparticles (AgNPs) are increasingly used in various commercial products. This increased use raises ecological concerns because of the large release of AgNPs into the environment. Once released, the local water chemistry has the potential to influence the environmental fates and behaviors of AgNPs. The impacts of dissolved oxygen and natural organic matter (NOM) on the dissolution and stability of AgNPs were investigated in synthetic and natural freshwaters for 7 days. In synthetic freshwater, the aggregation of AgNPs occurred due to the compression of the electric double layer, accompanied by the dissolution of AgNPs...
July 14, 2017: Environmental Pollution
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