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Medications affect fetal heart rate

Fiona Weeks, Loreto Pantoja, Jovita Ortiz, Jennifer Foster, Gabriel Cavada, Lorena Binfa
INTRODUCTION: Satisfaction with care during labor and birth has been associated with various obstetric variables. The purpose of this study was to determine which labor and birth procedures are significant predictors of maternal patient satisfaction in a large cross-sectional sample. METHODS: An observational, cross-sectional study of 1660 women giving birth in Chilean public hospital facilities was conducted from 2012 to 2013. Data were collected from 9 different hospitals in 8 regions of Chile using 2 instruments, including the American College of Nurse-Midwives Intrapartum Care Data Set and a locally validated measure of maternal well-being...
August 20, 2016: Journal of Midwifery & Women's Health
Leslie J Matthews, David B McConda, Trapper A J Lalli, Scott D Daffner
Managing orthopedic conditions in pregnant patients leads to challenges that must be carefully considered so that the safety of both the mother and the fetus is maintained. Both perioperative and intraoperative considerations must be made based on physiologic changes during pregnancy, risks of radiation, and recommendations for monitoring. Operative timing, imaging, and medication selection are also factors that may vary based on trimester and clinical scenario. Pregnancy introduces unique parameters that can result in undesirable outcomes for both mother and fetus if not handled appropriately...
October 2015: Orthopedics
G M Lockwood, N E Deveneau, A N Shridharani, E Y Strawn, J I Sandlow
This study sought to investigate whether isolated abnormal strict morphology (<5% normal forms) and very low strict morphology (0-1% normal forms) affects pregnancy rates in intrauterine insemination (IUI). This was a retrospective study performed at an Academic Medical Center/Reproductive Medicine Center. Four hundred and eight couples were included for 856 IUI cycles. 70 IUI cycles were performed in couples with abnormal strict morphology and otherwise normal semen parameters. Outcomes were measured as clinical pregnancy rate per IUI cycle as documented by fetal heart activity on maternal ultrasound...
November 2015: Andrology
Venu Jain, Radha Chari, Sharon Maslovitz, Dan Farine, Emmanuel Bujold, Robert Gagnon, Melanie Basso, Hayley Bos, Richard Brown, Stephanie Cooper, Katy Gouin, N Lynne McLeod, Savas Menticoglou, William Mundle, Christy Pylypjuk, Anne Roggensack, Frank Sanderson
OBJECTIVE: Physical trauma affects 1 in 12 pregnant women and has a major impact on maternal mortality and morbidity and on pregnancy outcome. A multidisciplinary approach is warranted to optimize outcome for both the mother and her fetus. The aim of this document is to provide the obstetric care provider with an evidence-based systematic approach to the pregnant trauma patient. OUTCOMES: Significant health and economic outcomes considered in comparing alternative practices...
June 2015: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Katarzyna Cypryk, Lukasz Bartyzel, Monika Zurawska-Klis, Wojciech Mlynarski, Agnieszka Szadkowska, Jan Wilczynski, Dorota Nowakowska, Lucyna A Wozniak, Wojciech Fendler
BACKGROUND: Much evidence has shown that pregnancies in women with preexisting diabetes are affected by an increased risk of maternal and fetal adverse outcomes, probably linked to poor glycemic control. Despite great progress in medical care, the rate of stillbirths remains much higher in diabetes patients than in the general population. Recent technological advances in the field of glucose monitoring and noninvasive fetal heart rate monitoring made it possible to observe the fetal-maternal dependencies in a continuous manner...
September 2015: Diabetes Technology & Therapeutics
R Douglas Wilson, R Douglas Wilson, Francois Audibert, Jo-Ann Brock, Carla Campagnolo, June Carroll, Lola Cartier, David Chitayat, Alain Gagnon, Jo-Ann Johnson, Sylvie Langlois, W Kim MacDonald, Lynn Murphy-Kaulbeck, Nanette Okun, Melanie Pastuck, Vanessa Popa
OBJECTIVE: To provide obstetrical and genetic health care practitioners with guidelines and recommendations for prenatal screening, diagnosis, and obstetrical management of fetal open and closed neural tube defects (OCNTD). OPTIONS: This review includes prenatal screening and diagnostic techniques currently being used for the detection of OCNTD including maternal serum alpha fetoprotein screening, ultrasound, fetal magnetic resonance imaging, and amniocentesis. OUTCOMES: To improve prenatal screening, diagnosis, and obstetrical management of OCNTD while taking into consideration patient care, efficacy, cost, and care procedures...
October 2014: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Jack Rychik, David Cohen, Kha M Tran, Anita Szwast, Shobha S Natarajan, Mark P Johnson, Julie S Moldenhauer, Nahla Khalek, Juan Martinez-Poyer, Alan W Flake, Holly L Hedrick, N Scott Adzick
INTRODUCTION: Fetal surgery for myelomeningocele (MMC) results in better outcomes compared to postnatal treatment. However, risks are present. We describe our experience with intraoperative fetal echocardiography during repair of MMC and report on the management of serious cardiovascular events. MATERIAL AND METHODS: The subjects included fetuses with intent to repair MMC from January 2011 to February 2014. The protocol involved continuous echocardiography in a looping, sequential manner of systolic function, heart rate and tricuspid and mitral valve regurgitation...
2015: Fetal Diagnosis and Therapy
Kristy A Kapfhamer, Kristen Fox, Michael Lund, Aniko Szabo, Robyn Baken, Timothy Klatt
INTRODUCTION: It is widely accepted that 75% of fetal heart rate tracings show sinusoidal patterns after butorphanol administration. We investigated whether this is true when sinusoidal patterns are defined using the 2008 National Institutes of Health guidelines. METHODS: Case-control study of women who delivered at Froedtert Hospital between June 2010 and December 2011. Inclusion criteria were maternal age older than 18 years, gestational age exceeding 24 weeks, and 60 minutes of interpretable fetal monitoring...
May 2014: Obstetrics and Gynecology
Ronny Cohen, Thierry Mallet, Brooks Mirrer, Pablo Loarte, Michael Gale, Paul Kastell
Peripartum cardiomyopathy is a life-threatening cardiac condition affecting pregnant women either late in pregnancy or early in the post-partum period. The latest studies show a dramatic improvement in the mortality rates of women affected with this disorder, which has been correlated with advances in medical therapy for heart failure. However, patients continue to die of this condition. The following case report describes a typical patient with peripartum cardiomyopathy diagnosed on clinical grounds, along with echocardiogram findings of severe systolic dysfunction and global hypokinesis consistent with dilated cardiomyopathy...
June 2014: Acute Cardiac Care
S F Hendawy, D Abdel-Mohsen, S E Ebrahim, H Ewais, S H Moussa, D A Khattab, N A Mohamed, H E Samaha
BACKGROUND: Systemic Lupus Erythematosus (SLE) has a tendency to occur in women in their reproductive years, causing complications during pregnancy and labour. Conversely, pregnancy can cause flares of disease activity, often necessitating immediate intervention. AIM OF STUDY: to study pregnancy related complications in patients with SLE. PATIENTS AND METHODS: The study included 48 SLE pregnant females. 27 patients with 38 pregnancies, their data viewed retrospectively from medical records, and 21 patients with 21 pregnancies followed up prospectively...
May 12, 2011: Clinical Medicine Insights. Reproductive Health
Gloria T Too, James B Hill
Hypertension affects 10% of pregnancies, many with underlying chronic hypertension, and approximately 1-2% will undergo a hypertensive crisis at some point during their lives. Hypertensive crisis includes hypertensive urgency and emergency; the American College of Obstetricians and Gynecologists describes a hypertensive emergency in pregnancy as persistent (lasting 15 min or more), acute-onset, severe hypertension, defined as systolic BP greater than 160 mmHg or diastolic BP >110 mmHg in the setting of pre-eclampsia or eclampsia...
August 2013: Seminars in Perinatology
B Gerecke, R Engberding
Isolated noncompaction cardiomyopathy (NCCM) is a rare genetically determined myocardial disease caused by abnormal fetal development of the myocardium resulting in a thin compacted and a thicker noncompacted layer of the affected left ventricular (LV) wall. The genetic basis of NCCM is heterogenous. Diagnosis can be made using echocardiography or magnetic resonance imaging. The diagnostic criteria for NCCM are still under discussion. Afflicted patients may present with various symptoms caused by arrhythmias, heart failure and cardioembolic events...
September 2012: Herzschrittmachertherapie & Elektrophysiologie
Svetlana Spremovic-Radjenovic, Aleksandra Gudovic, Gordana Lazovic, Jelena Marinkovic, Nebojsa Radunovic, Aleksandar Ljubic
CONTEXT: Fetuses from mothers with autoimmune thyroid disease (AITD) may be affected by antithyroid antibodies, antithyroid drugs, and iodine. OBJECTIVE: The study correlated fetal free T(4) (fT4) with fetal ultrasound parameters and maternal thyroid function, thyroid antibodies, and medication dose from mothers with AITD. DESIGN AND SETTING: The study was designed as a prospective cohort study and conducted in an academic referral center...
November 2012: Journal of Clinical Endocrinology and Metabolism
Silvia Batalha, Mónica Rebelo, Isabel Freitas, Agostinho Borges, Fátima Pinto
BACKGROUND: Congenital heart disease is the most frequent congenital malformation, affecting about 5-8 newborn per thousand live births. Nowadays it is possible to do prenatal diagnosis of these conditions with fetal echocardiography (EcoF) but because health resources are limited this exam must be ordered according to the criteria established by the Portuguese Health Department. AIMS: Evaluate the importance of the referral criteria for fetal echocardiography attending to the cardiac anomalies identified...
December 2011: Acta Médica Portuguesa
(no author information available yet)
Diagnoses of "complications of pregnancy, childbirth, and the puerperium" (ICD-9-CM: 630-679) include both morbid complications and indications for routine care of pregnant women. During 2001-2010, U.S. service members with live births (n=156,314) had 1.16 million medical encounters with primary diagnoses of "pregnancy complications". The most frequent diagnoses were "other current conditions", "other threatened labor" (e.g., false labor), "previous cesarean delivery" and "normal delivery". The number of complication-related medical encounters per pregnancy more than doubled during 2001-2010...
December 2011: MSMR
Hen Y Sela, Carolyn F Weiniger, Moshe Hersch, Arnon Smueloff, Neri Laufer, Sharon Einav
OBJECTIVE: To investigate the workup/treatment provided to pregnant motor vehicle accident (MVA) casualties in a mature trauma system. Adherence to recommendations was used to measure quality of care. BACKGROUND: MVAs affect approximately 3% of pregnant women. Trauma casualty outcome improves after implementation of guidelines. METHODS: A 5-year audit of clinical practice in 2 university hospitals with a trauma call system where the general surgeon is the primary care physician...
August 2011: Annals of Surgery
T Y Leung, O Stuart, D S Sahota, S S H Suen, T K Lau, T T Lao
OBJECTIVE: To examine the association between head-to-body delivery interval (HBDI) and cord arterial pH and base excess (BE), and the risk of development of hypoxic ischaemic encephalopathy (HIE). DESIGN: Retrospective review. SETTING: A university hospital. POPULATION: Pregnancies complicated with shoulder dystocia during the period 1995-2009. METHODS: Cases were identified from a search of the hospital electronic delivery records...
March 2011: BJOG: An International Journal of Obstetrics and Gynaecology
Charlene E Thornton, Angela Makris, Jane M Tooher, Robert F Ogle, Annemarie Hennessy
BACKGROUND: Cardiotocographic (CTG) recordings of the fetal heart remain standard obstetric practice among hypertensive women. Changes in the short-term variation (STV) in the fetal heart are often attributed to the effect of anti-hypertensive medications, regardless of the fact that this principle has never been validated. AIM: To assess the STV of CTG recordings pre- and post- the anti-hypertensive medication, clonidine. METHODS: Forty hypertensive pregnant women, already receiving the anti-hypertensive clonidine, were recruited...
October 2010: Australian & New Zealand Journal of Obstetrics & Gynaecology
Kaarin Mäkikallio, Ganesh Acharya, Tiina Erkinaro, Tomi Kavasmaa, Mervi Haapsamo, James C Huhta, Juha Räsänen
We investigated whether hypoxemia without acidemia affects ductus venosus (DV) blood velocity waveform pattern in sheep fetuses with intact placenta and whether worsening acidemia and impending fetal death are related to changes in DV velocimetry in fetuses with increased placental vascular resistance. A total of 34 fetuses were instrumented at 115-136/145 days of gestation. Placental embolization was performed in 22 fetuses on the fourth postoperative day, 24 h before the experiment. The control group was comprised of 12 fetuses with intact placenta...
April 2010: American Journal of Physiology. Heart and Circulatory Physiology
Mi Lim Chung, Byong Sop Lee, Ellen Ai-Rhan Kim, Ki-Soo Kim, Soo-Young Pi, Yeon Mi Oh, In Sook Park, Dong Man Seo, Hye Sung Won
BACKGROUND: Congenital heart disease (CHD) is the most common developmental malformation and the leading cause of neonatal mortality and morbidity. The introduction of fetal echocardiography has made prenatal diagnosis of CHD possible. OBJECTIVE: This study was conducted to investigate the impact of fetal echocardiography on the changing disease patterns and outcomes of CHD. METHODS: A retrospective analysis of data from infants with CHD admitted to the neonatal intensive care unit (NICU) of the Asan Medical Center during the time periods was performed...
June 2010: Neonatology
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