keyword
MENU ▼
Read by QxMD icon Read
search

Hbp

keyword
https://www.readbyqxmd.com/read/28728485/factors-associated-with-global-longitudinal-strain-decline-in-hypertensive-patients-with-normal-left-ventricular-ejection-fraction
#1
Nabila Soufi Taleb Bendiab, Abderrahim Meziane-Tani, Souhila Ouabdesselam, Nadera Methia, Samia Latreche, Latefa Henaoui, Jean-Jacques Monsuez, Salim Benkhedda
Background Early detection of risk factors for left ventricular (LV) dysfunction may be useful in patients with high blood pressure (HBP). Methods Patient from an outpatient HBP clinic underwent a two-dimensional Doppler-coupled echocardiography with determination of LV global longitudinal strain (GLS) by speckle-tracking. Results Among 200 patients (mean age 61.7 ± 9.7 years), 155 were overweight, 93 had diabetes, 83 had dyslipidemia, and 109 had uncontrolled HBP. LV hypertrophy (LVH) was found in 136 patients (68%), including concentric ( n = 106) and eccentric ( n = 30) LVH...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28725327/prevalence-of-undiagnosed-cardiovascular-risk-factors-in-adults-aged-20-40-a-cross-sectional-study-in-2016-in-jeddah-saudi-arabia
#2
Faisal Saed Alharthi, Jamilah Saad Alrahimi, Abdulrahman Ali Alotaibi, Daniah Ahmed Alhamdi, Bashair Mohammed Ibrahim, Yasmina Aymen Badeeb
BACKGROUND: Cardiovascular diseases (CVDs) are the first leading cause of death worldwide. In Saudi Arabia, CVDs are the major killers with a mortality rate of 46%. CVD risk factors are not exclusive to old populations. Thus, the purpose of this study was to approximately find the prevalence of these risk factors, particularly high blood pressure (HBP), high blood glucose (HBG), obesity, and smoking. METHODS: This cross-sectional was conducted in May 2016 and took place in the Ambulatory Care Center of King Abdulaziz Medical City, Jeddah...
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28722313/cellular-glycosylation-senses-metabolic-changes-and-modulates-cell-plasticity-during-emt
#3
REVIEW
P Carvalho-Cruz, F Alisson-Silva, A R Todeschini, W B Dias
Epithelial to mesenchymal transition (EMT) is a developmental program reactivated by tumor cells that leads to the switch from epithelial to mesenchymal phenotype. During EMT, cells are transcriptionally regulated to decrease E-cadherin expression while expressing mesenchymal markers such as vimentin, fibronectin and N-cadherin. Growing body of evidences suggest that cells engaged in EMT undergo a metabolic reprograming process, redirecting glucose flux toward Hexosamine Biosynthesis Pathway (HBP) which fuels aberrant glycosylation patterns that are extensively observed in cancer cells...
July 19, 2017: Developmental Dynamics: An Official Publication of the American Association of Anatomists
https://www.readbyqxmd.com/read/28715499/helicobacter-pylori-modulates-host-cell-responses-by-cagt4ss-dependent-translocation-of-an-intermediate-metabolite-of-lps-inner-core-heptose-biosynthesis
#4
Saskia C Stein, Eugenia Faber, Simon H Bats, Tatiana Murillo, Yvonne Speidel, Nina Coombs, Christine Josenhans
Highly virulent Helicobacter pylori cause proinflammatory signaling inducing the transcriptional activation and secretion of cytokines such as IL-8 in epithelial cells. Responsible in part for this signaling is the cag pathogenicity island (cagPAI) that codetermines the risk for pathological sequelae of an H. pylori infection such as gastric cancer. The Cag type IV secretion system (CagT4SS), encoded on the cagPAI, can translocate various molecules into cells, the effector protein CagA, peptidoglycan metabolites and DNA...
July 17, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28678544/possible-involvement-of-orphan-receptors-gpr88-and-gpr124-in-the-development-of-hypertension-in-spontaneously-hypertensive-rat
#5
L Calderón-Zamora, A Ruiz-Hernandez, R Romero-Nava, N León-Sicairos, A Canizalez-Román, E Hong, F Huang, S Villafaña
Hypertension (HBP) is a chronic disease characterized by increased blood pressure, which despite several treatments maintains a high morbi-mortality, which suggests that there are other mechanisms involved in this pathology, within which the orphan receptors could be candidates for the treatment of the HBP; these receptors are called orphan receptors because their ligand is unknown. These receptors have been suggested to participate in some pathologies because they are associated with various systems such as GPR88, which has been linked to the dopaminergic system, and GPR124 with angiogenesis, suggesting that these receptors could take part in HBP...
July 5, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28651555/prevalence-of-high-blood-pressure-subtypes-and-its-associations-with-bmi-in-chinese-children-a-national-cross-sectional-survey
#6
Yide Yang, Bin Dong, Shuo Wang, Yanhui Dong, Zhiyong Zou, Lianguo Fu, Jun Ma
BACKGROUND: Data on prevalence and characteristics of different high blood pressure subtypes are lacking among Chinese children. Regarding the mechanistic differences between isolated systolic high blood pressure and isolated diastolic high blood pressure and their different impact on end organ diseases, it is necessary to examine the prevalence of different high blood pressure subtypes in Chinese children and explore their associations with adiposity. METHODS: Data were derived from the baseline data of a multi-centered cluster randomized controlled trial involving participants from China...
June 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28645872/two-obesity-susceptibility-loci-in-lyplal1-and-etv5-independently-associated-with-childhood-hypertension-in-chinese-population
#7
Duo Lv, Dan Zhou, Yan Zhang, Shuai Zhang, Yi-Min Zhu
AIMS: Genome-wide association studies have identified novel obesity-associated susceptibility loci. Associations of these variants with childhood obesity have been studied in our previous research. The purpose of this study is to investigate if these loci are associated with hypertension being independent of obesity in Chinese children and adolescents. METHODS: Nineteen candidate SNPs were genotyped using Sequenom MassARRAY platform among Chinese children (N=2954, 514 hypertension and 2440 controls, aged 7-17years)...
June 20, 2017: Gene
https://www.readbyqxmd.com/read/28644127/mpi-depletion-enhances-o-glcnacylation-of-p53-and-suppresses-the-warburg-effect
#8
Nataly Shtraizent, Charles DeRossi, Shikha Nayar, Ravi Sachidanandam, Liora S Katz, Adam Prince, Anna P Koh, Adam Vincek, Yoav Hadas, Yujin Hoshida, Donald K Scott, Efrat Eliyahu, Hudson H Freeze, Kirsten C Sadler, Jaime Chu
Rapid cellular proliferation in early development and cancer depends on glucose metabolism to fuel macromolecule biosynthesis. Metabolic enzymes are presumed regulators of this glycolysis-driven metabolic program, known as the Warburg effect; however, few have been identified. We uncover a previously unappreciated role for Mannose phosphate isomerase (MPI) as a metabolic enzyme required to maintain Warburg metabolism in zebrafish embryos and in both primary and malignant mammalian cells. The functional consequences of MPI loss are striking: glycolysis is blocked and cells die...
June 23, 2017: ELife
https://www.readbyqxmd.com/read/28634368/preparation-and-properties-of-a-hyperbranch-structured-polyamine-adsorbent-for-carbon-dioxide-capture
#9
Hui He, Yajie Hu, Shuixia Chen, Linzhou Zhuang, Beibei Ma, Qinghua Wu
A fibrous adsorbent with amino-terminated hyperbranch structure (PP-AM-HBP-NH2) was prepared by grafting hyperbranched polyamine (HBP-NH2) onto the acrylamide-modified polypropylene (PP) fibers. The grafting of AM on PP fibers provided the active sites for introducing HBP-NH2 onto the PP fibers. This kind of "grafting to" procedure to synthesize hyperbranch-structured fiber could overcome the disadvantages of stepwise growth procedure, avoiding the complicated synthesis process and the requirement of strict experimental conditions...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28626731/how-to-differentiate-borderline-hepatic-nodules-in-hepatocarcinogenesis-emphasis-on-imaging-diagnosis
#10
REVIEW
Hyun Jeong Park, Byung Ihn Choi, Eun Sun Lee, Sung Bin Park, Jong Beum Lee
BACKGROUND: Rapid advances in liver imaging have improved the evaluation of hepatocarcinogenesis and early diagnosis and treatment of hepatocellular carcinoma (HCC). In this situation, detection of early-stage HCC in its development is important for the improvement of patient survival and optimal treatment strategies. Because early HCCs are considered precursors of progressed HCC, precise differentiation between a dysplastic nodule (DN), especially a high-grade DN, and early HCC is important...
June 2017: Liver Cancer
https://www.readbyqxmd.com/read/28626161/morning-and-evening-blood-pressures-are-associated-with-intima-media-thickness-in-a-general-population%C3%A3-the-hisayama-study
#11
Satoko Sakata, Jun Hata, Masayo Fukuhara, Koji Yonemoto, Naoko Mukai, Daigo Yoshida, Hiro Kishimoto, Toshio Ohtsubo, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya
BACKGROUND: The association of morning and evening home blood pressures (HBPs) with carotid atherosclerosis has been uncertain in general populations, so we aimed to investigate it in a general Japanese population.Methods and Results:We performed a cross-sectional survey of 2,856 community-dwelling individuals aged ≥40 years to examine the association of morning and evening HBPs with carotid mean intima-media thickness (IMT). The age- and sex-adjusted geometric averages of carotid mean IMT increased significantly with increasing morning HBP (optimal: 0...
June 14, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28624005/differentiation-between-cholangiocarcinoma-and-hepatocellular-carcinoma-with-target-sign-on-diffusion-weighted-imaging-and-hepatobiliary-phase-gadoxetic-acid-enhanced-mr-imaging-classification-tree-analysis-applying-capsule-and-septum
#12
Ji Hye Min, Young Kon Kim, Seo-Youn Choi, Woo Kyoung Jeong, Won Jae Lee, Sang Yun Ha, Soohyun Ahn, Hyeon Seon Ahn
OBJECTIVES: To assess the usefulness of classification tree analysis (CTA) for discrimination of hepatocellular carcinoma (HCC) with target sign on hepatobiliary phase (HBP) and/or diffusion-weighted image (DWI) from intrahepatic cholangiocarcinoma (ICC). METHODS: This retrospective study was approved by the institutional review board. From among the 811 patients with histopathologically proven 79 ICCs and 732 HCCs, 69 patients with 69 (87.3%) ICCs and 115 patients with 115 HCCs (15...
July 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28607606/diagnostic-value-of-gd-eob-dtpa-mri-for-hepatocellular-adenoma-a-meta-analysis
#13
Yongfei Guo, Wenjuan Li, Zhinan Xie, Yi Zhang, Yijie Fang, Wenli Cai, Guobin Hong
Objective: This study aimed to systematically review the gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-MRI) findings of hepatocellular adenoma (HCA), especially focusing on the diagnostic value of low signal intensity (SI) in the hepatocyte-phase (HBP) for differentiating HCA from focal nodular hyperplasia (FNH). Methods: A thorough literature search was conducted in PubMed, Excerpta Medica Database (EMBASE) and China National Knowledge Infrastructure databases (CNKI) to identify studies evaluating Gd-EOB-DTPA-MRI presentations of HCA...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28605498/effect-of-home-blood-pressure-on-inducing-remission-regression-of-microalbuminuria-in-patients-with-type-2-diabetes-mellitus
#14
Motonobu Nishimura, Yasuhisa Kato, Tsuyoshi Tanaka, Hideki Taki, Atsuhito Tone, Kazunori Yamada, Seiji Suzuki, Miho Saito, Yutaka Ando, Yoshiharu Hoshiyama
BACKGROUND: The Home Blood Pressure for Diabetic Nephropathy study is a prospective observational study conducted to determine the effect of home blood pressure (HBP) on remission/regression of microalbuminuria in patients with type 2 diabetes mellitus (DM). METHODS: Patients with type 2 DM having microalbuminuria were followed-up for 3 years. Remission of microalbuminuria was defined as shift from microalbuminuria to normoalbuminuria. Regression of microalbuminuria was defined as a 50% reduction in urinary albumin-creatinine ratio from baseline...
June 10, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28604339/obesity-markers-associated-to-albuminuria-in-a-primary-care-center-in-lima-per%C3%A3%C2%BA
#15
Alberto E Quintanilla, Álvaro Taype-Rondan, María Lazo-Porras, Percy Herrera-Añazco
OBJECTIVE: To evaluate the association between three obesity markers, body mass index (BMI), abdominal circumference (AC), waist to height ratio (WHtR), and albuminuria in adults seen in a primary health care center specialized in chronic diseases in Lima, Perú. METHODS: A cross-sectional, descriptive, retrospective study in adults who attended a primary health care center specialized in chronic diseases in 2011. Patients were divided into four categories: healthy subjects and patients with high blood pressure, with type 2 diabetes mellitus (T2DM), and with both diseases (HBP+T2DM)...
June 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/28585315/heparin-binding-protein-as-a-biomarker-of-acute-kidney-injury-in-critical-illness
#16
J Tydén, H Herwald, M Hultin, J Walldén, J Johansson
BACKGROUND: There is no biomarker with high sensitivity and specificity for the development of acute kidney injury (AKI) in a mixed intensive care unit (ICU) population. Heparin-binding protein (HBP) is released from granulocytes and causes increased vascular permeability which plays a role in the development of AKI in sepsis and ischemia. The aim of this study was to investigate whether plasma levels of HBP on admission can predict the development of AKI in a mixed ICU population and in the subgroup with sepsis...
June 5, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28582574/a-genetic-model-to-study-increased-hexosamine-biosynthetic-flux
#17
Sarah E Hugo, Amnon Schlegel
Recently, we identified harvest moon (hmn), a fully penetrant and expressive recessive zebrafish mutant with hepatic steatosis. Larvae showed increased triacylglycerol in the absence of other obvious defects. When we attempted to raise these otherwise normal appearing mutants to adulthood, we observed a developmental arrest and death in the early juvenile period. Here we report the positional cloning of the hmn locus and characterization of the defects caused by the mutation. Using bulk segregant analysis, fine mapping, and immunoblot assays we find that hmn mutants harbor a point mutation in an invariant residue within the sugar isomerase 1 domain of the gene encoding the rate-limiting enzyme of the hexosamine biosynthetic pathway (HBP) Glutamine-fructose-6-phosphate transamidase (Gfpt1)...
June 5, 2017: Endocrinology
https://www.readbyqxmd.com/read/28576401/-blood-pressure-values-in-adolescents-in-the-community-of-madrid-tables-based-on-the-mepafac-study
#18
A Molinero, M Cervero, M C Magro, T Partearroyo, P Zuluaga, A Martín
INTRODUCTION: High blood pressure (HBP) is a modifiable cardiovascular risk factor and its detection at early ages may allow strategies to be designed to reduce cardiovascular risk in adulthood. OBJECTIVES: To provide blood pressure (BP) values in a sample of adolescents using an electronic oscillometric device. MATERIAL AND METHODS: BP was measured according the European Society of Hypertension guidelines using an oscillometric device. Height and weight were also measured...
May 30, 2017: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/28575215/comparison-of-the-effects-of-selective-and-non-selective-his-bundle-pacing-on-cardiac-electrical-and-mechanical-synchrony
#19
Jinlong Zhang, Jianghong Guo, Xiaofeng Hou, Yao Wang, Zhiyong Qian, Kebei Li, Peibing Ge, Jiangang Zou
Aims: This study aimed to assess the acute effect of selective His bundle pacing (S-HBP), non-selective His bundle pacing (NS-HBP), and right ventricular septum pacing (RVSP) on electrical synchrony and left ventricular (LV) mechanical synchrony using electrocardiogram and phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Methods and results: Totally 39 patients eligible for pacemaker were enrolled. Thirty-seven patients underwent successful His bundle pacing (HBP) including S-HBP in 23 and NS-HBP in 14 patients, respectively...
May 31, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28575205/relationship-of-hypertension-and-systolic-blood-pressure-with-the-risk-of-stroke-or-bleeding-in-patients-with-atrial-fibrillation-the-fushimi-af-registry
#20
Mitsuru Ishii, Hisashi Ogawa, Takashi Unoki, Yoshimori An, Moritake Iguchi, Nobutoyo Masunaga, Masahiro Esato, Yeong-Hwa Chun, Hikari Tsuji, Hiromichi Wada, Koji Hasegawa, Mitsuru Abe, Masaharu Akao
BACKGROUND: Hypertension is considered a major risk factor of stroke and systemic embolism (SE) as well as bleeding in patients with atrial fibrillation (AF). The purpose of this study was to investigate the relationship of hypertension and systolic blood pressure (SBP) with the risk of stroke/SE or bleeding in AF patients. METHODS: The Fushimi AF Registry, a community-based prospective survey, was designed to enroll all of the AF patients in Fushimi-ku, Kyoto. Fushimi-ku is densely populated with a total population of 283,000...
May 30, 2017: American Journal of Hypertension
keyword
keyword
24827
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"