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https://www.readbyqxmd.com/read/28098712/business-education-for-plastic-surgeons-a-systematic-review-development-and-implementation-of-a-business-principles-curriculum-in-a-residency-program
#1
Bahar Zarrabi, Karen K Burce, Stella M Seal, Scott D Lifchez, Richard J Redett, Kevin Frick, Amir H Dorafshar, Carisa M Cooney
BACKGROUND: Rising healthcare costs, decreasing reimbursement rates, and changes in American healthcare are forcing physicians to become increasingly business-minded. Both academic and private plastic surgeons can benefit from being educated in business principles. We conducted a systematic review to identify existing business curricula and integrated a business principles curriculum into residency training. METHODS: We anonymously surveyed our department regarding perceived importance of business principles and performed a systematic literature review from 1993-2013 using PubMed and Embase to identify residency training programs that had designed/implemented business curricula...
January 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28098236/wind-wave-behavior-in-fetch-and-depth-limited-estuaries
#2
Arash Karimpour, Qin Chen, Robert R Twilley
Wetland dominated estuaries serve as one of the most productive natural ecosystems through their ecological, economic and cultural services, such as nursery grounds for fisheries, nutrient sequestration, and ecotourism. The ongoing deterioration of wetland ecosystems in many shallow estuaries raises concerns about the contributing erosive processes and their roles in restraining coastal restoration efforts. Given the combination of wetlands and shallow bays as landscape components that determine the function of estuaries, successful restoration strategies require knowledge of wind wave behavior in fetch and depth limited water as a critical design feature...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28097316/evaluation-of-structural-progression-in-arrhythmogenic-right-ventricular-dysplasia-cardiomyopathy
#3
Thomas P Mast, Cynthia A James, Hugh Calkins, Arco J Teske, Crystal Tichnell, Brittney Murray, Peter Loh, Stuart D Russell, Birgitta K Velthuis, Daniel P Judge, Dennis Dooijes, Ryan J Tedford, Jeroen F van der Heijden, Harikrishna Tandri, Richard N Hauer, Theodore P Abraham, Pieter A Doevendans, Anneline S J M Te Riele, Maarten J Cramer
Importance: Considerable research has described the arrhythmic course of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). However, objective data characterizing structural progression, such as ventricular enlargement and cardiac dysfunction, in ARVD/C are relatively scarce. Objectives: To define the extent of structural progression, identify determinants of structural progression, and determine the association between structural progression and electrocardiographic (ECG) changes in patients with ARVD/C...
January 11, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28095623/xenopus-as-a-model-for-studies-in-mechanical-stress-and-cell-division
#4
REVIEW
G A Stooke-Vaughan, L A Davidson, S Woolner
We exist in a physical world, and cells within biological tissues must respond appropriately to both environmental forces and forces generated within the tissue to ensure normal development and homeostasis. Cell division is required for normal tissue growth and maintenance, but both the direction and rate of cell division must be tightly controlled to avoid diseases of over-proliferation such as cancer. Recent studies have shown that mechanical cues can cause mitotic entry and orient the mitotic spindle, suggesting that physical force could play a role in patterning tissue growth...
January 17, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28092213/cellular-and-molecular-factors-influencing-tendon-repair
#5
Sushmitha Durgam, Matthew Stewart
Tendons are complex, hierarchically organized connective tissues that transmit tensile forces between muscles and tendons. Tendon injuries are among the most common orthopedic problems with long-term disability as a frequent consequence due to prolonged healing time. Further, the repair tissue is of inferior quality, predisposing patients to high rates of recurrence following initial injury. Co-ordinated cellular processes and biological factors under the influence of mechanical loading are involved in tendon healing and our understanding of these events lags behind other musculoskeletal tissues...
January 16, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/28089974/cardiopulmonary-disease-development-in-anti-rna-polymerase-iii-positive-systemic-sclerosis-comparative-analyses-from-an-unselected-prospective-patient-cohort
#6
Anna-Maria Hoffmann-Vold, Øyvind Midtvedt, Anders H Tennøe, Torhild Garen, May Brit Lund, Trond M Aaløkken, Arne K Andreassen, Fadi Elhage, Cathrine Brunborg, Eli Taraldsrud, Øyvind Molberg
OBJECTIVE: Extensive skin disease and renal crisis are hallmarks of anti-RNA polymerase III (RNAP)-positive systemic sclerosis (SSc), while lung and heart involvement data are conflicting. Here, the aims were to perform time-course analyses of interstitial lung disease (ILD) and pulmonary hypertension (PH) in the RNAP subset of a prospective unselected SSc cohort and to use the other autoantibody subsets as comparators. METHODS: The study cohort included 279 patients with SSc from the observational Oslo University Hospital cohort with complete data on (1) SSc-related autoantibodies, (2) paired, serial analyses of lung function and fibrosis by computed tomography, and (3) PH verified by right heart catheterization...
January 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28089854/effects-of-adolescent-methamphetamine-and-nicotine-exposure-on-behavioral-performance-and-map-2-immunoreactivity-in-the-nucleus-accumbens-of-adolescent-mice
#7
Jordan M Buck, Alysse S Morris, Sydney J Weber, Jacob Raber, Jessica A Siegel
The neurotoxic effects of methamphetamine (MA) exposure in the developing and adult brain can lead to behavioral alterations and cognitive deficits in adults. Previous increases in the rates of adolescent MA use necessitate that we understand the behavioral and cognitive effects of MA exposure during adolescence on the adolescent brain. Adolescents using MA exhibit high rates of nicotine (NIC) use, but the effects of concurrent MA and NIC in the adolescent brain have not been examined, and it is unknown if NIC mediates any of the effects of MA in the adolescent...
January 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28081355/oral-delivery-of-probiotics-in-poultry-using-ph-sensitive-tablets
#8
Tao Jiang, Hui-Shan Li, Geon Goo Han, Bijay Singh, Sang-Kee Kang, Jin-Duck Bok, Dae-Duk Kim, Zhong-Shan Hong, Yun-Jaie Choi, Chong-Su Cho
As alternatives to antibiotics in live stocks, probiotics have been used although most of them in the form of liquid or semisolid formulations which show low cell viability after oral administration. Therefore, suitable dry dosage forms should be developed for live stocks to protect probiotics against the low pH in the stomach such that the products have higher probiotics survivability. Here, in order to develop a dry dosage forms of probiotics for poultry, we used hydroxyproyl methylcellulose phthalate 55 (HPMCP 55) as a tablet forming matrix to develop probiotics in a tablet form for poultry...
January 12, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28077762/inverse-problems-in-reduced-order-models-of-cardiovascular-haemodynamics-aspects-of-data-assimilation-and-heart-rate-variability
#9
Sanjay Pant, Chiara Corsini, Catriona Baker, Tain-Yen Hsia, Giancarlo Pennati, Irene E Vignon-Clementel
Inverse problems in cardiovascular modelling have become increasingly important to assess each patient individually. These problems entail estimation of patient-specific model parameters from uncertain measurements acquired in the clinic. In recent years, the method of data assimilation, especially the unscented Kalman filter, has gained popularity to address computational efficiency and uncertainty consideration in such problems. This work highlights and presents solutions to several challenges of this method pertinent to models of cardiovascular haemodynamics...
January 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28074742/development-and-validation-of-an-rp-hplc-method-for-the-determination-of-vinpocetine-and-folic-acid-in-the-presence-of-a-vinpocetine-alkaline-degradation-product-in-bulk-and-in-capsule-form
#10
Ehab F Elkady, Marwa H Tammam, Ayman A Mohamed
An alkaline-forced degradation hydrolytic product of vinpocetine was prepared and characterized by <sup>1</sup>H-NMR, FTIR spectroscopy, and MS. Subsequently, a simple, selective, and validated reversed-phase HPLC method was developed for the simultaneous estimation of vinpocetine and folic acid in the presence of a vinpocetine alkaline degradation product. Chromatographic separation was achieved using an isocratic mobile phase consisting of acetonitrile-0.02 M KH<sub>2</sub>PO<sub>4</sub> [containing 0...
January 11, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28073981/effect-of-resin-ducts-and-sap-content-on-infestation-and-development-of-immature-stages-of-anastrepha-obliqua-and-anastrepha-ludens-diptera-tephritidae-in-four-mango-sapindales-anacardiaceae-cultivars
#11
Larissa Guillén, Ricardo Adaime, Andrea Birke, Olinda Velázquez, Guillermo Angeles, Fernando Ortega, Eliel Ruíz, Martín Aluja
We determined the influence of resin ducts, sap content, and fruit physicochemical features of four mango cultivars (Criollo, Manila, Ataulfo, and Tommy Atkins) on their susceptibility to the attack of the two most pestiferous fruit fly species infesting mangoes in Mexico: Anastrepha ludens (Loew) and Anastrepha obliqua (Macquart). We performed three studies: 1) analysis of resin ducts in mango fruit exocarp to determine the density and area occupied by resin ducts in each mango cultivar, 2) assessment of mango physicochemical features including fruit sap content, and 3) a forced infestation trial under field conditions using enclosed fruit-bearing branches to expose mangoes to gravid A...
January 10, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28073446/harmful-algal-bloom-forecast-system-for-sw-ireland-part-i-description-and-validation-of-an-operational-forecasting-model
#12
Tomasz Dabrowski, Kieran Lyons, Glenn Nolan, Alan Berry, Caroline Cusack, Joe Silke
A 3D primitive equation coastal ocean model for southwest Ireland, called the Bantry Bay model, was developed and implemented operationally. Validated model outputs have multiple uses. One of the incentives to develop the model was to explore the possible transport pathways that carry harmful algae blooms (HAB) into Bantry Bay. The model is nested offline in a regional North East Atlantic operational model. Surface forcing is taken from the half-degree Global Forecasting System, available at three-hourly intervals...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28068776/force-field-parametrization-of-colloidal-cdse-nanocrystals-using-an-adaptive-rate-monte-carlo-optimization-algorithm
#13
Salvatore Cosseddu, Ivan Infante
In a typical colloidal CdSe nanocrystal more than 50% of the atoms are located at the surface. These atoms can give rise to electronic traps that can deteriorate the performance of optoelectronic devices made of these nanomaterials. A key challenge in this field is thus to understand with atomistic detail the chemical processes occurring at the nanocrystal surface. Molecular dynamics simulations represent an important tool to unveil these processes, but its implementation is strongly limited by the difficulties of finely tuning classical force fields parameters, primarily caused by the unavailability of experimental data of these materials that are suitable in the parametrization procedures...
January 10, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28068290/a-collection-system-for-dry-solid-residues-from-exhaled-breath-for-analysis-via-atomic-force-microscopy
#14
Victor N Morozov, Andrey Y Mikheev
Exhaled air contains sub-micron droplets of lung liquid, which potentially bear biomarkers of lung diseases. After dehydration they form dry residue particles (DRPs). As a first step in developing techniques to characterize individual DRPs, a new electrostatic collector was designed in which DRPs are charged within a unipolar corona charger, concentrated in a cone funnel, and deposited onto a limited area of a highly oriented pyrolytic graphite surface. The collector captures 80%-90% of DRPs at an optimal flow rate of 0...
January 9, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28066693/society-of-pediatric-psychology-workforce-survey-development-of-survey-methods-sample-characteristics-and-lessons-learned
#15
Tim Wysocki, Cheryl L Brosig, Marisa E Hilliard
There are few detailed workforce studies of specialty fields within professional psychology, and none have been reported for pediatric psychology since 2006. Availability of such data could facilitate more-informed decision making by students and trainees, psychologists pursuing employment opportunities, and psychologists involved in employment or compensation negotiations. This article describes the work of a task force of the American Psychological Association (APA) Division 54 (Society of Pediatric Psychology) in the design, construction, pretesting, distribution, and data management for the Society of Pediatric Psychology (SPP) Workforce Survey...
March 2016: Clinical Practice in Pediatric Psychology
https://www.readbyqxmd.com/read/28065549/an-experimental-investigation-of-underwater-spread-of-oil-spill-in-a-shear-flow
#16
Hongjun Zhu, Jiahui You, Honglei Zhao
The time taken for spilt oil to appear firstly at the sea surface and its location are two key issues for emergency response. The underwater spread of oil spill in a shear flow was studied experimentally in a re-circulating water channel. The high speed imaging technology was employed to record the whole transport process of oil spilt from a leak of a submarine pipe to the surface. Based on the experimental results, three underwater transport types are identified, which are single droplet pattern (model A), linear chain pattern (model B) and oil plume pattern (model C), respectively...
January 5, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28063187/characterization-of-degradation-products-of-silodosin-under-stress-conditions-by-liquid-chromatography-ftms
#17
Sukanya Pandeti, T Narender, S Prabhakar, Reddy Jagadeswar Thota
RATIONALE: Silodosin (SDN) is a novel α1 -adrenoceptor antagonist in the treatment of benign prostatic hyperplasia (BPH). The presence of degradation products in a drug affects not only the quality, but also the safety and efficacy of drug formulation. Thus, it is essential to develop an efficient analytical method which could be useful to selectively separate, identify and characterise of all possible degradation products of SDN is mandatory in drug development processes. METHODS: SDN was subjected to forced degradation under hydrolytic (acid, base and neutral), oxidative, photolytic and thermal stress conditions...
January 6, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28060001/incidence-of-skin-tears-and-risk-factors-a-systematic-literature-review
#18
Kelly Cristina Strazzieri-Pulido, Giovana Ribau Picolo Peres, Ticiane Carolina Gonçalves Faustino Campanili, Vera Lúcia Conceição de Gouveia Santos
Skin tears are traumatic wounds resulting from friction and shearing forces. Clinical practice strongly indicates that skin tears are a prevalent problem but their incidence is not well established in the literature. This systematic literature review identified and evaluated the available literature on the incidence and risk factors for skin tears in adults and the elderly. Inclusion criteria were epidemiological studies published in English, Spanish, or Portuguese languages from January 1990 through June 2014 and available in full text...
January 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28054698/digital-microelectromechanical-sensor-with-an-engineered-polydimethylsiloxane-pdms-bridge-structure
#19
Lingju Meng, Shicheng Fan, Seyed Milad Mahpeykar, Xihua Wang
Functional electronic devices integrated on flexible substrates are of great interest in both academia and industry for their potential applications in wearable technologies. Recently, there have been an increasing number of investigations on developing new materials for flexible strain sensors and pressure sensors, with the aim of achieving better sensitivity and detection ranges. However, the analog signal outputs of these sensors are accompanied with challenges regarding device reproducibility and reliability...
January 5, 2017: Nanoscale
https://www.readbyqxmd.com/read/28053245/synaptic-control-of-the-shape-of-the-motoneuron-pool-input-output-function
#20
Randall K Powers, Charles J Heckman
Although motoneurons have often been considered to be fairly linear transducers of synaptic input, recent evidence suggests that strong persistent inward currents (PICs) in motoneurons allow neuromodulatory and inhibitory synaptic inputs to induce large nonlinearities in the relation between the level of excitatory input and motor output. To try and estimate the possible extent of this nonlinearity, we developed a pool of model motoneurons designed to replicate the characteristics of motoneuron input-output properties measured in medial gastrocnemius motoneurons in the decerebrate cat using voltage-clamp and current-clamp techniques...
January 4, 2017: Journal of Neurophysiology
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