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Rate of force development

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https://www.readbyqxmd.com/read/28654843/naturalistic-assessment-of-the-learner-license-period
#1
J P Ehsani, S G Klauer, C Zhu, P Gershon, T A Dingus, B G Simons-Morton
The purpose of this study was to describe the characteristics and progression of practice driving during the learner license period in a sample of teenagers. During the first and last 10h of practice driving, we examined (1) the amount, variety and complexity of conditions of practice; (2) the nature of parental instruction; and (3) errors that teens made while driving. Data were collected from 90 teens and 131 parents living in Virginia, USA, using in-vehicle cameras, audio recorders, GPS and trip recorders...
June 24, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28652223/ilae-survey-of-neuropsychology-practice-in-pediatric-epilepsy-surgery-evaluation
#2
Madison M Berl, Mary Lou Smith, Christine Bulteau
To determine the extent to which specific neuropsychological measures are in common use around the world for the assessment of children who are candidates for epilepsy surgery. As part of the work of the International League Against Epilepsy Pediatric Surgical Task Force, a survey was developed and distributed online. The survey consisted of questions related to demographics, training experience, general practice, and specific measures used and at what frequency. Seventy-eight clinicians with an average of 13...
June 24, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28649405/bacillus-subtilis-biofilm-development-in-the-presence-of-soil-clay-minerals-and-iron-oxides
#3
Wenting Ma, Donghai Peng, Sharon L Walker, Bin Cao, Chun-Hui Gao, Qiaoyun Huang, Peng Cai
Clay minerals and metal oxides, as important parts of the soil matrix, play crucial roles in the development of microbial communities. However, the mechanism underlying such a process, particularly on the formation of soil biofilm, remains poorly understood. Here, we investigated the effects of montmorillonite, kaolinite, and goethite on the biofilm formation of the representative soil bacteria Bacillus subtilis. The bacterial biofilm formation in goethite was found to be impaired in the initial 24 h but burst at 48 h in the liquid-air interface...
2017: NPJ Biofilms and Microbiomes
https://www.readbyqxmd.com/read/28648628/impact-of-titin-strain-on-the-cardiac-slow-force-response
#4
REVIEW
Younss Ait-Mou, Mengjie Zhang, Jody L Martin, Marion L Greaser, Pieter P de Tombe
Stretch of myocardium, such as occurs upon increased filling of the cardiac chamber, induces two distinct responses: an immediate increase in twitch force followed by a slower increase in twitch force that develops over the course of several minutes. The immediate response is due, in part, to modulation of myofilament Ca(2+) sensitivity by sarcomere length (SL). The slowly developing force response, termed the Slow Force Response (SFR), is caused by a slowly developing increase in intracellular Ca(2+) upon sustained stretch...
June 22, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28646582/comprehensive-mathematical-model-of-oxidative-phosphorylation-valid-for-physiological-up-to-pathological-conditions
#5
Margit Heiske, Thierry Letellier, Edda Klipp
We developed a mathematical model of oxidative phosphorylation (OXPHOS) that allows for a precise description of mitochondrial function with respect to the respiratory flux and the ATP production. The model reproduced flux-force relationships under various experimental conditions (state 3 and 4, uncoupling, shortage of respiratory substrate) as well as time courses, exhibiting correct P/O ratios. The model was able to reproduce experimental threshold curves for perturbations of the respiratory chain complexes, the F1 F0 -ATP synthase, the ADP/ATP carrier, the phosphate/OH carrier, and the proton leak...
June 24, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28645855/training-surgical-residents-with-a-haptic-robotic-central-venous-catheterization-simulator
#6
David F Pepley, Adam B Gordon, Mary A Yovanoff, Katelin A Mirkin, Scarlett R Miller, David C Han, Jason Z Moore
OJECTIVE: Ultrasound guided central venous catheterization (CVC) is a common surgical procedure with complication rates ranging from 5 to 21 percent. Training is typically performed using manikins that do not simulate anatomical variations such as obesity and abnormal vessel positioning. The goal of this study was to develop and validate the effectiveness of a new virtual reality and force haptic based simulation platform for CVC of the right internal jugular vein. DESIGN: A CVC simulation platform was developed using a haptic robotic arm, 3D position tracker, and computer visualization...
June 20, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28640007/evaluation-of-pulse-height-control-for-rapid-isometric-contractions-in-college-sprinters
#7
Seiji Ono, Atsushi Itaya, Tatsuya Hayami, Keigo Ohyama-Byun, Tomohiro Kizuka
The ability of rapid force development is one of the important factors for improving physical performance. It has been known that rapid isometric force is controlled by a central motor program to maintain the rise time relatively constant independent of force amplitude (pulse height control). The advantage of using pulse height control is that it increases the rate of force with force amplitude. However, this strategy is believed to be applicable up to about 50-60% of maximal voluntary contractions (MVC). When the force level increases further, individuals often switch to pulse width control to increase the time to peak force...
June 21, 2017: Neuroreport
https://www.readbyqxmd.com/read/28639474/custom-rapid-prototype-thumb-prosthesis-for-partial-hand-amputation-a-case-report
#8
Ashley Quinn Swartz, Kristi Turner, Laura Miller, Todd Kuiken
BACKGROUND: Due to advancements in three-dimensional printing, custom-made prostheses are becoming more viable options for persons with difficult cases of prosthetic management. The purpose of this article was to develop a custom voluntary-closing, body-powered thumb mechanism for a partial-hand amputee who had amputations of the index finger and thumb on the left, non-dominant hand. Case description and methods: The prosthesis model was manufactured using rapid prototype technology and was developed to provide greater force and functionality, and to decrease overall size compared to traditional hand prostheses...
June 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28639152/influence-of-muscle-groups-activation-on-proximal-femoral-growth-tendency
#9
Priti Yadav, Sandra J Shefelbine, Eva Pontén, Elena M Gutierrez-Farewik
Muscle and joint contact force influence stresses at the proximal growth plate of the femur and thus bone growth, affecting the neck shaft angle (NSA) and femoral anteversion (FA). This study aims to illustrate how different muscle groups' activation during gait affects NSA and FA development in able-bodied children. Subject-specific femur models were developed for three able-bodied children (ages 6, 7, and 11 years) using magnetic resonance images. Contributions of different muscle groups-hip flexors, hip extensors, hip adductors, hip abductors, and knee extensors-to overall hip contact force were computed...
June 22, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28633950/a-multi-scale-integrated-modeling-framework-to-measure-comprehensive-impact-of-coastal-reclamation-activities-in-yellow-river-estuary-china
#10
Yan Xu, Yanpeng Cai, Tao Sun, Qian Tan
In this paper, an improved multi-scale integrated modeling framework has been established to evaluate coastal reclamation intensity (CRI). About 7 indicators are considered, including ecological degradation intensity (EDI), hydrodynamic disturbance (IHD), engineering types, water quality, economic investment, population growth, and reclaimed land area. Meanwhile, an integrated framework enhanced methods in terms of (a) measuring intensity of ecological degradation process under multi-scale impact, (b) developing the indicator system of CRI, and discussing the driving forces and trends of coastal reclamation, (c) determining fuzzy preference relations of weight and calculating the specific value of CRI with the case study areas of Yellow River estuary from 2000 to 2015...
June 17, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28626133/simple-synthesis-hydrogenated-castor-oil-fatty-amide-wax-and-its-coating-characterization
#11
Xiuzhu Yu, Ning Wang, Rui Zhang, Zhong Zhao
A simple method for incorporating amine groups in hydrogenated castor oil (HCO) to produce wax for beeswax or carnauba wax substitution in packaging and coating was developed. From the conversion rate of the products, HCO was reacted with ethanolamine at 150°C for 5 h, and the molar ratio of HCO and ethanolamine was 1:4. The hardness of the final product was seven times higher than that of beeswax, the cohesiveness of the final product was 1.3 times higher than that of beeswax and approximately one half of that of carnauba wax, and the melting point of the final product is 98°C...
June 13, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28623713/indirect-sinusoidal-vibrations-induces-an-acute-increase-in-explosive-strength
#12
Leandro V de Paula, Pedro V S Moreira, Rudolf Huebner, Leszek A Szmuchrowski
The purpose of this study was to examine the acute effect of indirect vibration on neuromuscular responses and fatigue resistance (electromyographic activity - EMG and force) during isometric exercise. Nineteen healthy men (age=22.4±2.7years; body mass=76.4±12.9kg, height=175±6.7cm) performed isometric elbow flexion exercises in three experimental treatments: only isometric exercise (control - CON); isometric exercise with the addition of sinusoidal vibrations (SVE1; frequency=20Hz, displacement=3.55±0...
August 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28622887/genetic-etiology-of-oral-cancer
#13
REVIEW
Johar Ali, Bibi Sabiha, Hanif Ullah Jan, Syed Adnan Haider, Abid Ali Khan, Saima S Ali
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. It accounts for 2.5% of all new cancer cases and 1.9% of all cancer deaths annually. More than 90% of oral cancers (occurring in the mouth, lip, and tongue) are oral squamous cell carcinoma. The incidence rate of oral cancer varies widely throughout the world, with an evident prevalence in South Asian countries. This high incidence occurs in correlation with oral cancer-associated behaviors such as alcohol, tobacco use...
July 2017: Oral Oncology
https://www.readbyqxmd.com/read/28622020/the-effect-of-direct-and-indirect-force-transmission-on-peri-implant-bone-stress-a-contact-finite-element-analysis
#14
Annike Rand, Meike Stiesch, Michael Eisenburger, Andreas Greuling
In almost all finite element (FE) studies in dentistry, virtual forces are applied directly to dentures. The purpose of this study was to develop a FE model with non-linear contact simulation using an antagonist as force transmitter and to compare this with a similar model that uses direct force transmission. Furthermore, five contact situations were created in order to examine their influence on the peri-implant bone stresses, which are relevant to the survival rate of implants. It was found that the peri-implant bone stresses were strongly influenced by the kind of force transmission and contact number...
August 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28621384/stability-indicating-uhplc-pda-assay-for-simultaneous-determination-of-antazoline-hydrochloride-and-naphazoline-hydrochloride-in-ophthalmic-formulations
#15
Amir Ali, Umar Farooq, Mahmood Ahmed, Muhammad Athar, Kashif Nadeem, Ghulam Murtaza
In the present study, a newly developed method based on ultrahigh performance liquid chromatography (UHPLC) was optimized for the simultaneous determination of antazoline hydrochloride (ANZ) and naphazoline hydrochloride (NFZ) in ophthalmic formulations. Isocratic separation of ANZ and NFZ was performed at 40 °C with an ACE Excel 2 C18-PFP column (2 μm, 2.1 × 100 mm) at a flow rate of 0.6 mL min-1 whereas the mobile phase consisted of acetonitrile/phosphate buffer (60:40, v/v, pH 3.0) containing 0.5% triethylamine...
June 2017: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/28620766/phenotype-transformation-of-aortic-valve-interstitial-cells-due-to-applied-shear-stresses-within-a-microfluidic-chip
#16
Xinmei Wang, Joohyung Lee, Mir Ali, Jungkyu Kim, Carla M R Lacerda
Despite valvular heart diseases constituting a significant medical problem, the acquisition of information describing their pathophysiology remains difficult. Due to valvular size, role and location within the body, there is a need for in vitro systems that can recapitulate disease onset and progression. This study combines the development of an in vitro model and its application in the mechanical stimulation of valvular cell transformation. Specifically, porcine aortic valvular interstitial cells (PAVIC) were cultured on polydimethylsiloxane microfluidic devices with or without exposure to shear stresses...
June 15, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28619011/to-be-active-through-indoor-climbing-an-exploratory-feasibility-study-in-a-group-of-children-with-cerebral-palsy-and-typically-developing-children
#17
Mark Schram Christensen, Thor Jensen, Camilla B Voigt, Jens Bo Nielsen, Jakob Lorentzen
BACKGROUND: Cerebral Palsy (CP) is the most common cause of motor disabilities in children and young adults and it is also often associated with cognitive and physiological challenges. Climbing requires a multifaceted repertoire of movements, participants at all levels of expertise may be challenged functionally and cognitively, making climbing of great potential interest in (re)habilitation settings. However, until now only few research projects have investigated the feasibility of climbing as a potential activity for heightening physical activity in children with CP and the possible beneficial effects of climbing activities in populations with functional and/or cognitive challenges...
June 15, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28617909/development-of-a-flow-evolution-network-model-for-the-stress-strain-behavior-of-poly-l-lactide
#18
Maureen L Dreher, Srinidhi Nagaraja, Jorgen Bergstrom, Danika Hayman
Computational modeling is critical to medical device development and has grown in its utility for predicting device performance. Additionally, there is an increasing trend to use absorbable polymers for the manufacturing of medical devices. However, computational modeling of absorbable devices is hampered by a lack of appropriate constitutive models that capture their viscoelasticity and post-yield behavior. The objective of this study was to develop a constitutive model that incorporated viscoplasticity for a common medical absorbable polymer...
June 15, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28611042/competition-between-dna-methylation-nucleotide-synthesis-and-anti-oxidation-in-cancer-versus-normal-tissues
#19
Sha Cao, Xiwen Zhu, Chi Zhang, Hong Qian, Heinz-Bernd Schuttler, Jian-Ping Gong, Ying Xu
Global DNA hypomethylation occurs in many cancer types but there is no explanation for its differential occurance or possible impact on cancer cell physiology. Here we address these issues with a computational study of genome-scale DNA methylation in 16 cancer types. Specifically, we identified (1) a possible determinant for global DNA methylation in cancer cells, and (2) a relationship between levels of DNA methylation, nucleotide synthesis and intracellular oxidative stress in cells. We developed a system of kinetic equations to capture the metabolic relations among DNA methylation, nucleotide synthesis, and anti-oxidative stress response, including their competitions for methyl and sulfur groups, based on known information about one-carbon metabolism and trans-sulfuration pathways...
June 13, 2017: Cancer Research
https://www.readbyqxmd.com/read/28608183/acc-aats-aha-ase-asnc-scai-scct-sts-2017-appropriate-use-criteria-for-coronary-revascularization-in-patients-with-stable-ischemic-heart-disease-a-report-of-the-american-college-of-cardiology-appropriate-use-criteria-task-force-american-association-for-thoracic
#20
Manesh R Patel, John H Calhoon, Gregory J Dehmer, James Aaron Grantham, Thomas M Maddox, David J Maron, Peter K Smith
The American College of Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, and American Association for Thoracic Surgery, along with key specialty and subspecialty societies, have completed a 2-part revision of the appropriate use criteria (AUC) for coronary revascularization. In prior coronary revascularization AUC documents, indications for revascularization in acute coronary syndromes and stable ischemic heart disease (SIHD) were combined into 1 document. To address the expanding clinical indications for coronary revascularization, and to align the subject matter with the most current American College of Cardiology/American Heart Association guidelines, the new AUC for coronary artery revascularization were separated into 2 documents addressing SIHD and acute coronary syndromes individually...
June 12, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
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