Parastu Kasaie, Cameron Stewart, Elizabeth Humes, Lucas Gerace, Jinbing Zhang, Michael J Silverberg, Michael A Horberg, Peter F Rebeiro, Emily P Hyle, Viviane D Lima, Cherise Wong, M John Gill, Kelly Gebo, Richard Moore, Mari M Kitahata, Keri N Althoff
BACKGROUND: The age-distribution of men who have sex with men (MSM) continues to change in the 'Treat-All' era as effective test-and-treat programs target key-populations. However, the nature of these changes and potential racial heterogeneities remain uncertain. METHODS: The PEARL model is an agent-based simulation of MSM in HIV care in the US, calibrated to data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). RESULTS: PEARL projects a gradual decrease in median age of MSM at ART initiation from 36 to 31 years during 2010-2030, accompanied by reductions in mortality among Black, White, and Hispanic MSM on ART by 63...
October 7, 2021: Annals of Epidemiology