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https://www.readbyqxmd.com/read/28821984/nonassociation-of-homocysteine-gene-polymorphisms-with-treatment-outcome-in-south-indian-tamil-rheumatoid-arthritis-patients
#1
Niveditha Muralidharan, Reena Gulati, Durga Prasanna Misra, Vir S Negi
The aim of the study was to look for any association of MTR 2756A>G and MTRR 66A>G gene polymorphisms with clinical phenotype, methotrexate (MTX) treatment response, and MTX-induced adverse events in South Indian Tamil patients with rheumatoid arthritis (RA). A total of 335 patients with RA were investigated. MTR 2756A>G gene polymorphism was analyzed by PCR-RFLP, and MTRR 66A>G SNP was analyzed by TaqMan 5' nuclease assay. The allele frequencies were compared with HapMap groups. MTR 2756G allele was found to be associated with risk of developing RA...
August 18, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/28821782/rapid-dwarfing-of-an-insular-mammal-the-feral-cattle-of-amsterdam-island
#2
Roberto Rozzi, Mark V Lomolino
The island rule describes a graded trend in insular populations of vertebrates from gigantism in small species to dwarfism in large species. The dwarfing of large mammals on islands has been observed both in the present fauna and in the fossil record. Elephants, hippopotami, deer, and other species became dwarfed on islands scattered all over the world, from the Mediterranean Sea to Indonesia, from the Eastern to Western Pacific Ocean, from the Caribbean to Canary Islands. The most rapid and well documented cases of island dwarfing known thus far took place over thousands of years...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28820881/vector-competence-of-populations-of-aedes-aegypti-from-three-distinct-cities-in-kenya-for-chikungunya-virus
#3
Sheila B Agha, Edith Chepkorir, Francis Mulwa, Caroline Tigoi, Samwel Arum, Milehna M Guarido, Peris Ambala, Betty Chelangat, Joel Lutomiah, David P Tchouassi, Michael J Turell, Rosemary Sang
BACKGROUND: In April, 2004, chikungunya virus (CHIKV) re-emerged in Kenya and eventually spread to the islands in the Indian Ocean basin, South-East Asia, and the Americas. The virus, which is often associated with high levels of viremia in humans, is mostly transmitted by the urban vector, Aedes aegypti. The expansion of CHIKV presents a public health challenge both locally and internationally. In this study, we investigated the ability of Ae. aegypti mosquitoes from three distinct cities in Kenya; Mombasa (outbreak prone), Kisumu, and Nairobi (no documented outbreak) to transmit CHIKV...
August 18, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28820789/suicide-resilience-and-connectedness-across-the-lifespan-lessons-from-american-indian-and-alaska-native-elders
#4
Satya Rao, Dylan Pell, Elizabeth S England-Kennedy
Rates of suicide and associated costs are high and increasing in the United States. From 1999 through 2014, the age-adjusted suicide rate increased 24%, with the pace of increase being greater since 2006. American Indian and Alaska Native persons have significantly lower rates of suicides than other ethnic groups as elders despite experiencing some of the highest rates during adolescence. This article examines literature pertaining to suicide rates in American Indian and Alaska Native communities and proposes a framework for understanding their lower rates of suicide as elders...
October 2017: Family & Community Health
https://www.readbyqxmd.com/read/28820732/ecological-perspectives-on-youth-alcohol-consumption-in-the-kuala-lumpur-conurbation-a-place-based-study-in-malaysia
#5
Sangeeta Kaur Singh, Lee Voon Kaen, Low Weng Hei, Amanda Villiers-Tuthill, Pascale Allotey, Daniel D Reidpath
Objective The objectives of this study were to investigate the patterns of alcohol consumption and ecological factors influencing those patterns in the Klang Valley. The study focuses on youth from the Chinese, Indian and Malay ethnic groups in Malaysia, resident in urban and semi-urban areas of the Klang Valley. Methods Data were collected with a combination of interviews and self-administered questionnaires available in Bahasa Malaysia and English were adapted from the Centers for Disease Control (CDC) Youth Risk Behavior Survey...
August 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28820730/knowledge-of-hepatitis-b-virus-infection-and-its-control-practices-among-dental-students-in-an-indian-city
#6
Vishal Khandelwal, Sushma Khandelwal, Neetu Gupta, Ullal Anand Nayak, Namrata Kulshreshtha, Sudhindra Baliga
Background Hepatitis B virus infection is a general cause of chronic hepatitis, liver cirrhosis and hepato-cellular carcinoma worldwide. It is highly contagious. It is an important reason for morbidity and mortality in the Indian population. Oral health professionals are at the highest risk. Vaccination for hepatitis B can prevent this deadly disease. Methods The present study was designed to evaluate the degree of awareness, knowledge of hepatitis B infection and status of hepatitis B vaccination among dental students...
August 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28820697/case-report-treatment-of-widespread-nodular-post-kala-azar-dermal-leishmaniasis-with-extended-dose-liposomal-amphotericin-b-in-bangladesh-a-series-of-four-cases
#7
Ariful Basher, Shomik Maruf, Proggananda Nath, Md Golam Hasnain, Muhammod Abdul Mukit, Azim Anuwarul, Fatima Aktar, Rupen Nath, Afm Akhtar Hossain, Abul Hasnat Milton, Dinesh Mondal, Abul Khair Mohammad Sumsuzzaman, Ridwanur Rahman, Mohammad Abul Faiz
Post kala-azar dermal leishmaniasis (PKDL) is a skin manifestation which usually appears after visceral leishmaniasis. It is now proved that PKDL patients serve as a reservoir for anthropometric leishmanial transmission. Hence, to achieve the kala-azar elimination target set by the World Health Organization in the Indian Subcontinent, PKDL cases should be given priority. The goal of treatment for PKDL should be early reepithelizlization and rapid cure, but unfortunately this has been difficult to achieve, especially for patients with severe lesions...
August 14, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28820169/aflibercept-for-recurrent-or-recalcitrant-polypoidal-choroidal-vasculopathy-in-indian-eyes-early-experience
#8
Aditya Bansal, Muna Bhende, Tarun Sharma, Pramod Bhende, Suchetana Mukherjee
Treatment guidelines for symptomatic polypoidal choroidal vasculopathy (PCV) have been described, but the management of recurrent or recalcitrant PCV is a challenge. The newer anti-vascular endothelial growth factor: aflibercept has shown promise in the treatment of both treatment naive and recalcitrant PCV in studies outside India. We present the minimum 6 months results of intravitreal aflibercept in recurrent and recalcitrant PCV in Indian eyes after multiple injections of bevacizumab/ranibizumab with or without photodynamic therapy...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820160/patient-satisfaction-and-acceptance-of-spherical-equivalent-spectacles-correction-wear-in-rural-india
#9
B Sandeep Reddy, Taraprasad Das, Ghansyam S Mirdha, Nagavardhan Reddy
PURPOSE: The aim of this study was to explore the possibilities of acceptance of a ready-to-dispense spherical equivalent (SE) of spherocylindrical (SC) correction spectacles in rural India. METHODS: Snellen visual acuity with SE power of refracted SC lenses was prospectively collected from all individuals visiting vision centers in Phase 1 (vision correction accuracy) of the study conducted in two South Indian districts. The satisfaction level was recorded by asking one standard question...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820157/incidence-outcomes-and-risk-factors-for-hemorrhagic-complications-in-eyes-with-polypoidal-choroidal-vasculopathy-following-photodynamic-therapy-in-indian-subjects
#10
Pukhraj Rishi, Ekta Rishi, Minal Sharma, Aditya Maitray, Muna Bhende, Lingam Gopal, Tarun Sharma, Dhanashree Ratra, Parveen Sen, Pramod Bhende, Chetan Rao, Pradeep Susvar
PURPOSE: To evaluate the incidence, outcomes, and risk factors for hemorrhagic complications in eyes with polypoidal choroidal vasculopathy (PCV) following photodynamic therapy (PDT). METHODS: Medical records of 94 eyes of 86 consecutive patients with PCV who underwent PDT between January 2007 and December 2014 were retrospectively reviewed. The diagnosis of PCV was based on clinical features and indocyanine green angiography. Eyes were treated with PDT monotherapy or a combination of PDT plus anti-vascular endothelial growth factor...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820152/back-pain-in-ophthalmology-national-survey-of-indian-ophthalmologists
#11
Ramesh Venkatesh, Sumit Kumar
PURPOSE: The aim is to assess the prevalence, severity, and associations of back pain among Indian ophthalmologists. METHODS: A self-reporting questionnaire was sent to ophthalmologists with valid e-mail addresses registered with the All India Ophthalmological Society. The survey was open for responses for 2 months. RESULTS: A total of 651 (5.96%) responses were obtained; 394 (61%) males and 257 (39%) females. Half (50%) of responses were obtained from doctors belonging to 31-40 years' age group...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28819897/teachers-and-parents-perspectives-on-a-curricular-subject-of-religion-and-spirituality-for-indian-schools-a-pilot-study-toward-school-mental-health-program
#12
Parameshwaran Ramakrishnan, Andrew Baccari, Uma Ramachandran, Syed Faiz Ahmed, Harold G Koenig
Religious-spiritual (R/S) education helps medical students cope with caregiving stress and gain skills in interpersonal empathy needed for clinical care. Such R/S education has been introduced into K-12 and college curricula in some developed nations and has been found to positively impact student's mental health. Such a move has not yet been seen in the Indian education system. This paper aimed to examine perspectives of teachers and parents in India on appropriateness, benefits, and challenges of including R/S education into the school curriculum and also to gather their impressions on how a R/S curriculum might promote students' health...
August 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28819831/biodiversity-variability-and-metal-accumulation-strategies-in-plants-spontaneously-inhibiting-fly-ash-lagoon-india
#13
Suchita Mukhopadhyay, Vivek Rana, Adarsh Kumar, Subodh Kumar Maiti
Out of 29 plant species taken into consideration for biodiversity investigations, the present study screened out Cyperus rotundus L., Calotropis procera (Aiton) W.T. Aiton, Croton bonplandianus Baill., Eclipta prostrata (L.) L., and Vernonia cinerea (L.) Less. as the most suitable metal-tolerant plant species (high relative density and frequency) which can grow on metal-laden fly ash (FA) lagoon. Total (aqua-regia), residual (HNO3) and plant available (CaCl2) metal concentrations were assessed for the clean-up of metal-contaminated FA disposal site using naturally colonized plants...
August 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28819621/an-unusual-cause-of-postaural-swelling-kimura-s-disease
#14
Purodha Prasad, Swati Tandon, Vasun Batra, Ishwar Singh
INTRODUCTION: Kimura's disease (KD) is an allergic inflammatory disorder of unknown etiology endemic in Orientals. Kimura's disease was first mentioned by Kimm and Szeto in China in 1937. Kimura's disease is commonly encountered in Asia and is mostly reported in Japan, China, Singapore and Honkong. However, only a few cases have been reported in the Indian subcontinent. CASE REPORT: A case of Kimura's disease in a young male managed by surgery is reported in addition to a literature review...
July 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28819266/amalaki-rasayana-a-traditional-indian-drug-enhances-cardiac-mitochondrial-and-contractile-functions-and-improves-cardiac-function-in-rats-with-hypertrophy
#15
Vikas Kumar, Kumar A Aneesh, K Kshemada, Kumar G S Ajith, Raj S S Binil, Neha Deora, G Sanjay, A Jaleel, T S Muraleedharan, E M Anandan, R S Mony, M S Valiathan, Kumar T R Santhosh, C C Kartha
We evaluated the cardioprotective effect of Amalaki Rasayana (AR), a rejuvenating Ayurvedic drug prepared from Phyllanthus emblica fruits in the reversal of remodeling changes in pressure overload left ventricular cardiac hypertrophy (LVH) and age-associated cardiac dysfunction in male Wistar rats. Six groups (aging groups) of 3 months old animals were given either AR or ghee and honey (GH) orally; seventh group was untreated. Ascending aorta was constricted using titanium clips in 3 months old rats (N = 24; AC groups) and after 6 months, AR or GH was given for further 12 months to two groups; one group was untreated...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819148/analysis-and-comparative-genomics-of-r997-the-first-sxt-r391-integrative-and-conjugative-element-ice-of-the-indian-sub-continent
#16
Michael P Ryan, Patricia Armshaw, John A O'Halloran, J Tony Pembroke
The aim of this study was to analyse R997, the first integrative and conjugative element (ICE) isolated from the Indian Sub-Continent, and to determine its relationship to the SXT/R391 family of ICEs. WGS of Escherichia coli isolate AB1157 (which contains R997) was performed using Illumina sequencing technology. R997 context was assessed by de novo assembly, gene prediction and annotation tools, and compared to other SXT/R391 ICEs. R997 has a size of 85 Kb and harbours 85 ORFs. Within one of the variable regions a HMS-1 β-lactamase resistance gene is located...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819020/inquiry-is-ordered-into-child-deaths-at-indian-hospital
#17
Priyanka Pulla
No abstract text is available yet for this article.
August 17, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28817863/prevention-detection-and-management-of-diabetes-in-south-dakota
#18
Amy L Hogue, Mark K Huntington
Diabetes mellitus (DM) is increasing in prevalence nationwide and in South Dakota, with an especially high prevalence in its American Indian population. Screening is not recommended for type 1 DM, but is for type 2 DM and pre-diabetes in certain populations. Fasting glucose, two-hour glucose tolerance test, or hemoglobin A1c are appropriate screening options. Treatment can include diabetic self-management education programs and medications. In addition to glycemic control, other cardiovascular risk factors must be reduced in these patients and specific testing and consultations should be performed to detect complications such as nephropathy or retinopathy...
2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28816487/associations-between-bullying-involvement-protective-factors-and-mental-health-among-american-indian-youth
#19
Kari Gloppen, Barbara McMorris, Amy Gower, Marla Eisenberg
Bullying involvement as a victim or perpetrator is associated with depression and suicidality, and American Indian (AI) youth experience a disproportionately high rate of these mental health issues. This study assessed whether AI young people involved in bullying were more likely to experience negative mental health problems than AI youth who were not involved in bullying, and identified protective factors that might support this particularly vulnerable population. Data come from 1,409 8th, 9th, and 11th Grade AI students who completed the 2013 Minnesota Student Survey...
August 17, 2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28816220/incidents-of-violence-against-doctors-in-india-can-these-be-prevented
#20
Neeraj Nagpal
Violence against doctors is on the rise all over the world. However, India has a unique problem. Meagre government spending on healthcare has resulted in poor infrastructure and human resource crunch in government hospitals. Hence, people are forced to seek private healthcare. Small and medium private healthcare establishments, which provide the bulk of healthcare services, are isolated, disorganized and vulnerable to violence. Violence against health service providers is only a manifestation of this malady...
March 2017: National Medical Journal of India
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