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https://www.readbyqxmd.com/read/29045689/sensitivity-to-house-dust-mites-allergens-with-atopic-asthma-and-its-relationship-with-cd14-c-159t-polymorphism-in-patients-of-west-bengal-india
#1
Amlan Ghosh, Shampa Dutta, Sanjoy Podder, Priti Mondal, Arghya Laha, Nimai Chandra Saha, Saibal Moitra, Goutam Kumar Saha, Richard Johnson
India is the home to around 15-20 million asthmatics, and asthma prevalence is increasing in Indian metropolitan area, including Kolkata, West Bengal. Complex interactions of genetic and environmental factors are involved in asthma. Genome-wide search for susceptible loci regulating IgE response (atopy) have identified a candidate gene CD14 which is most important in the context of allergic responses of respiratory system. This study was aimed to investigate the role of house dust and house dust mites in development of bronchial asthma and to explore the possible association of candidate gene CD14 with disease manifestation among Kolkata patient population...
October 17, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29045274/recruiting-american-indian-alaska-native-students-to-medical-school-a-multi-institutional-alliance-in-the-u-s-southwest
#2
Marlene P Ballejos, Polly Olsen, Tanisha Price-Johnson, Cindy Garcia, Tassy Parker, Robert E Sapién, Valerie Romero-Leggott
PROBLEM: Despite national efforts to diversify the physician workforce, American Indian/Alaska Native (AI/AN) individuals have the least representation of all major racial and ethnic groups. Limited resources at state medical schools present institution-level recruitment challenges. Unified efforts to engage AI/AN students in premedical education activities are needed. APPROACH: The medical schools at the Universities of Arizona (Phoenix and Tucson), Colorado, New Mexico, and Utah identified a collective need to increase student diversity, particularly with regard to AI/AN students...
October 17, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29044716/effect-of-central-corneal-thickness-on-intraocular-pressure-and-comparison-of-topcon-ct-80-non-contact-tonometry-with-goldmann-applanation-tonometry
#3
Tarannum Mansoori, Nagalla Balakrishna
BACKGROUND: To compare intraocular pressure (IOP) measurements obtained with the Topcon CT-80 non-contact tonometer (NCT) and Goldmann applanation tonometer (GAT), in different ranges of IOP in normal and glaucoma subjects, and to assess the influence of central corneal thickness (CCT) on the IOP measurements in Asian Indian eyes. METHODS: Four hundred and two eyes of 402 subjects (193 newly diagnosed primary open angle glaucoma [POAG] and 209 normal) were enrolled for this prospective study...
October 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29044105/late-holocene-slowdown-of-the-indian-ocean-walker-circulation
#4
Mahyar Mohtadi, Matthias Prange, Enno Schefuß, Tim C Jennerjahn
Changes in tropical zonal atmospheric (Walker) circulation induce shifts in rainfall patterns along with devastating floods and severe droughts that dramatically impact the lives of millions of people. Historical records and observations of the Walker circulation over the 20th century disagree on the sign of change and therefore, longer climate records are necessary to better project tropical circulation changes in response to global warming. Here we examine proxies for thermocline depth and rainfall in the eastern tropical Indian Ocean during the globally colder Last Glacial Maximum (19-23 thousand years ago) and for the past 3000 years...
October 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/29044060/interocular-symmetry-of-retinal-nerve-fiber-layer-and-optic-nerve-head-parameters-measured-by-cirrus-high-definition-optical-coherence-tomography-in-a-normal-pediatric-population
#5
Neelam Pawar, Devendra Maheshwari, Meenakshi Ravindran, Renagappa Ramakrishnan
PURPOSE: To determine interocular differences in the retinal nerve fiber layer (RNFL) and optic nerve head (ONH) parameters in a pediatric population using Cirrus high-definition optical coherence tomography (HD-OCT). METHODS: Seventy normal Indian children aged 5-17 years presenting to the Pediatric Clinic were included in this observational cross-sectional study. All subjects underwent a comprehensive ophthalmologic examination and an evaluation of the RNFL and ONH by Cirrus HD-OCT...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29044056/association-of-polymorphisms-in-the-intron-of-tcf4-gene-to-late-onset-fuchs-endothelial-corneal-dystrophy-an-indian-cohort-study
#6
Bhavna S Rao, Arokiasamy Tharigopala, Sudhir R Rachapalli, Rama Rajagopal, Nagasamy Soumittra
PURPOSE: Fuchs endothelial corneal dystrophy (FECD) is a progressive degenerative disease of the corneal endothelium. It is genetically heterogeneous and follows either an autosomal dominant or sporadic pattern of inheritance. Here, we have explored the association of four previously reported intronic single nucleotide polymorphisms and intronic CTG repeat expansions in TCF4 gene to FECD in an Indian cohort. METHODS: The cohort consisting of 52 sporadic late-onset cases, 5 early-onset cases, and 148 controls was taken for the study...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29043958/oceaniglobus-indicus-gen-nov-sp-nov-a-member-of-the-family-rhodobacteraceae-isolated-from-surface-seawater
#7
Jianyang Li, Zhaobin Huang, Qiliang Lai, Xiupian Liu, Guangyi Wang, Zongze Shao
A Gram-stain-negative, non-motile, aerobic and heterotrophic strain, designated 1-19b(T), was isolated from surface seawater in the Indian Ocean. The cells were ovoid or coccus (0.8-1.0 µm in diameter) with no flagellum. Activities of catalase and oxidase were positive. Growth was observed at salinity of 0.5-10 (%NaCl, w/v) with an optimum of 3-4, at pH 5-10 with an optimum of 7-8, and at 5-37 °C with an optimum of 28-35 °C. It accumulated poly-β-hydroxybutyrate granules inside the cell. Bacteriochlorophyll a was absent...
October 18, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29043220/enhancement-of-antioxidant-quality-of-green-leafy-vegetables-upon-different-cooking-method
#8
Afzal Hossain, Mst Afifa Khatun, Mahfuza Islam, Roksana Huque
Antioxidant rich green leafy vegetables including garden spinach leaf, water spinach leaf, Indian spinach leaf, and green leaved amaranth were selected to evaluate the effects of water boiling and oil frying on their total phenolic content (TPC), total flavonoid content (TFC), reducing power (RP), and antioxidant capacity. The results revealed that there was a significant increase in TPC, TFC, and RP in all the selected vegetables indicating the effectiveness of the cooking process on the antioxidant potential of leafy vegetables...
September 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29042199/temporal-expression-and-gonadotropic-regulation-of-aromatase-and-estrogen-receptors-in-the-ovary-of-wall-lizard-hemidactylus-flaviviridis-correlation-with-plasma-estradiol-and-ovarian-follicular-development
#9
Mamta Tripathy, Umesh Rai
The current study in Indian wall lizard Hemidactylus flaviviridis for the first time demonstrates the reproductive phase-dependent expression pattern of aromatase (cyp19) and estrogen receptor subtypes (er-α and er-β) as well as their gonadotropic regulation in the ovary of a squamate. The expression of cyp19 remained low during regressed phase, increased markedly in recrudescent and declined sharply in breeding phase. Further, temporal profile of plasma estradiol 17-β (E2) was found to be relatively parallel to the expression pattern of ovarian cyp19...
October 14, 2017: Steroids
https://www.readbyqxmd.com/read/29042011/differences-in-innate-and-adaptive-immune-response-traits-of-pahari-indian-non-descript-indigenous-breed-and-jersey-crossbred-cattle
#10
Subhash Verma, Aneesh Thakur, Shailja Katoch, Chander Shekhar, Aasim Habib Wani, Sandeep Kumar, Shweta Dohroo, Geetanjali Singh, Mandeep Sharma
Cattle are an integral part of the largely agrarian economy of India. Indigenous breeds of cattle comprise about 80% of total cattle population of the country and contribute significantly to the overall milk production. There are 40 recognized indigenous breeds of cattle and a number of uncharacterized non-descript cattle. Pahari cattle of Himachal Pradesh in Northern India are one such non-descript indigenous breed. Here we describe a comprehensive evaluation of haematobiochemical parameters and innate and adaptive immune response traits of Pahari cattle and a comparison with Jersey crossbred cattle...
October 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/29041838/psychodermatology-liaison-clinic-in-india-a-working-model
#11
Nupur Goyal, Shrutakirthi Shenoi, Smitha S Prabhu, K Sreejayan, Ravindra Munoli, Shweta Rai
Literature reports suggest that up to 30% of dermatology patients have associated psychiatric co-morbidity. A psychodermatology liaison (PD) clinic is essential to deal with such patients, which is almost non-existent in the Indian scenario. In order to report the working pattern of such a clinic and to determine its efficacy with the help of Dermatology Life Quality Index (DLQI) and Short Assessment of Patient Satisfaction (SAPS) questionnaires, we investigated patients with suspected psychocutaneous diseases in an open-labelled two-year prospective study...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/29041837/infective-keratitis-in-indian-patients-with-corneal-dystrophies
#12
Anita Ganger, Noopur Gupta, Ankit S Tomar, Murugesan Vanathi, Radhika Tandon
All eight patients seen with various types of corneal dystrophy, a rare hereditary corneal disease, presented with infective keratitis. Unilateral microbial invasion was seen in all patients and the visual acuity of the affected eyes was <6/60 at presentation. We highlight our impression that microbial invasion can occur with all types of epithelial and stromal corneal dystrophy, including macular corneal dystrophy. Regular follow-up to maintain a healthy ocular surface is recommended to avert blindness in such patients...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/29040920/ancestry-prediction-in-singapore-population-samples-using-the-illumina-forenseq-kit
#13
Anantharaman Ramani, Yongxun Wong, Si Zhen Tan, Bing Hong Shue, Christopher Syn
The ability to predict bio-geographic ancestry can be valuable to generate investigative leads towards solving crimes. Ancestry informative marker (AIM) sets include large numbers of SNPs to predict an ancestral population. Massively parallel sequencing has enabled forensic laboratories to genotype a large number of such markers in a single assay. Illumina's ForenSeq DNA Signature Kit includes the ancestry informative SNPs reported by Kidd et al. In this study, the ancestry prediction capabilities of the ForenSeq kit through sequencing on the MiSeq FGx were evaluated in 1030 unrelated Singapore population samples of Chinese, Malay and Indian origin...
August 15, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29040824/perceived-harm-as-a-mediator-of-the-relationship-between-social-norms-and-marijuana-use-and-related-consequences-among-american-indian-youth
#14
Mark A Prince, Randall C Swaim, Linda R Stanley, Bradley T Conner
BACKGROUND: American Indian (AI) youth are at increased risk for marijuana use with marijuana use rates on or near reservations 1.6-4.8 times higher compared to non-AI youth in the same regions (Stanley et al., 2014). One outcome of the changing social and legal acceptance of marijuana is a decrease in perceived risk among adolescents. It is unknown whether these changes in perceptions of marijuana-related harm will presage higher rates of use among AI youth. Perceptions of others use (i...
October 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29040050/latent-autoimmune-diabetes-in-adults-in-north-indian-region-assessment-of-%C3%AE-cell-function-metabolic-and-immunological-features
#15
Alok Kumar, Alberto de Leiva
BACKGROUND: We undertook a study to assess β-cell function and metabolic and immunological features of patients with latent autoimmune diabetes in adults (LADA) and assess heterogeneity within LADA based on low and high glutamic acid decarboxylase autoantibodies (GADA) titers. METHODS: A total of 139 patients with adult-onset diabetes were examined cross-sectionally in the National capital region of Northern India. Medical history of all subjects was reviewed with the aim of collecting clinical data...
October 17, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29039041/evaluation-of-antioxidant-potential-of-essential-oils-of-some-commonly-used-indian-spices-in-in-vitro-models-and-in-food-supplements-enriched-with-omega-6-and-omega-3-fatty-acids
#16
Anwesa Bag, Rabi Ranjan Chattopadhyay
The aim of this study was to evaluate and compare the antioxidant potential of essential oils of some commonly used Indian spices (black pepper, cinnamon, clove, coriander and cumin) in various in vitro models and in food supplements enriched with omega-6 and omega-3 fatty acids. In vitro antioxidant potential was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging and Fe(2+) ion-chelating methods and lipid oxidation stabilisation potential was evaluated in bulk soybean oil-fish oil mixture and their oil-in-water emulsions using peroxide value (PV), p-anisidine value (p-AV) and total oxidation value as indicators of oxidation...
October 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29039038/assessment-of-ghg-mitigation-and-cdm-technology-in-urban-transport-sector-of-chandigarh-india
#17
Nitin Bhargava, Bhola Ram Gurjar, Suman Mor, Khaiwal Ravindra
The increase in number of vehicles in metropolitan cities has resulted in increase of greenhouse gas (GHG) emissions in urban environment. In this study, emission load of GHGs (CO, N2O, CO2) from Chandigarh road transport sector has been estimated using Vehicular Air Pollution Inventory (VAPI) model, which uses emission factors prevalent in Indian cities. Contribution of 2-wheelers (2-w), 3-wheelers (3-w), cars, buses, and heavy commercial vehicles (HCVs) to CO, N2O, CO2, and total GHG emissions was calculated...
October 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29038941/spatial-and-temporal-heavy-metal-distribution-and-surface-water-characterization-of-kanjli-wetland-a-ramsar-site-india-using-different-indices
#18
Navdeep Singh, Manpreet Kaur, Jatinder Kaur Katnoria
Suitability of surface water of Kanjli wetland, Punjab (India) during the period of 2013-2015 was assessed for drinking, irrigation and aquatic life using a water quality index (WQI), heavy metal pollution index (HPI) and aquatic toxicity index (ATI). WQI was calculated using 14 physico-chemical parameters while HPI determination used nine heavy metals like As, Cd, Co, Cr, Cu, Fe, Mn, Pb and Zn. WQI revealed that Kanjli wetland contained medium quality water (irrigation and aquatic life). Cr, Cd and Co exceeded desirable limits of World Health Organization (WHO, Guidelines for drinking-water quality, World Health Organization, Geneva, 2011) and Indian drinking water standard (2012) during all the three seasons (monsoon, post monsoon and winter)...
October 16, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29038635/pleomorphic-adenoma-of-soft-palate-unusual-occurrence-of-the-major-tumor-in-minor-salivary-gland-a-case-report-and-literature-review
#19
Deepak Passi, Hari Ram, Shubha Ranjan Dutta, Laxman Revansidha Malkunje
Salivary gland tumours constitute about less than 4 % of all head and neck tumours. Pleomorphic adenoma, also called benign mixed tumour, is the most common tumour of the salivary glands. About 80-90 % of these tumours occur in the major salivary glands mainly parotid gland and 10 % of them occur in the minor salivary glands. The most common site for pleomorphic adenoma of the minor salivary glands is the palate, followed by the lips and the cheeks. Other rare sites include the floor of the mouth, tongue, tonsil, pharynx, retromolar area and the nasal cavity...
December 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29037447/a-quinidine-non-responsive-novel-kcnt1-mutation-in-an-indian-infant-with-epilepsy-of-infancy-with-migrating-focal-seizures
#20
Priyanka Madaan, Prashant Jauhari, Aparajita Gupta, Biswaroop Chakrabarty, Sheffali Gulati
Epilepsy of infancy with migrating focal seizures {a.k.a malignant migrating partial seizures of infancy (MMPSI)} is an uncommon epileptic encephalopathy with a poor prognosis. Migrating focal seizures with autonomic features, developmental stagnation and refractoriness to treatment are its key features. It is caused by genetic defects in various ion channels, most common being sodium activated potassium channel (KCNT1), found in up to 50% of cases. With advent of genetic diagnosis and precision medicine, many targeted therapies have been identified...
October 13, 2017: Brain & Development
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