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Microwave thermoablation

Konstantinos Segkos, Carl Schmidt, Fadi Nabhan
Hürthle cell thyroid cancer (HCTC) is a less common form of differentiated thyroid cancer. It rarely metastasizes to the liver, and when it does, the metastasis is almost never isolated. Here we report a 62-year-old male with widely invasive Hürthle cell thyroid cancer, who underwent total thyroidectomy and received adjuvant treatment with I-131 with posttreatment scan showing no evidence of metastatic disease. His thyroglobulin however continued to rise after that and eventually an isolated liver metastasis was identified...
2017: Case Reports in Endocrinology
Adrian Kastler, Alexandre Krainik, Linda Sakhri, Mireille Mousseau, Bruno Kastler
PURPOSE: To evaluate feasibility of using a thermocouple for temperature monitoring during microwave (MW) ablation of metastatic bone disease. MATERIALS AND METHODS: This retrospective study comprised 16 patients (8 men with mean age 63 y and 8 women with mean age 59 y) with 18 bone metastases treated with MW ablation using a thermocouple between March 2012 and October 2015. The mean maximum tumor size was 29.5 mm. MW ablation power was set between 15 W and 40 W and applied for 1-6 minutes...
March 2017: Journal of Vascular and Interventional Radiology: JVIR
Pál Ákos Deák, Dávid Ádám Korda, Attila Doros
INTRODUCTION: Depending on their size and location, some benign tumors can cause prolonged discomfort and even rupture and fatal bleeding in severe cases. Hitherto the therapeutic strategies for such lesions were observation, surgery and in selected cases transarterial embolization. AIM: Our aim was to present the possibilities of thermoablation for treating lesions. METHOD: Here we present interventions of four patients in Semmelweis University Department of Transplantation and Surgery...
December 2016: Orvosi Hetilap
Salvatore Gruttadauria, Duilio Pagano, Alessandro Tropea, Davide Cintorino, Luisa Castellana, Pasquale Bonsignore, Calogero Ricotta, Gaetano Piccolo, Giovanni Vizzini, Angelo Luca
BACKGROUND: The surgical therapy of choice for hepatocellular carcinoma (HCC) is liver transplantation (LT) or hepatic resection, although only a small percentage of patients can undergo these procedures. Microwave thermal ablation (MWTA) can be an effective alternative treatment for HCC that complicates a cirrhotic liver disease, either as a final procedure or for downstaging patients on the waiting list for LT, or in combination with resective surgery to achieve oncological radicality...
October 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Elisa Francone, Elena Muzio, Luigi D'Ambra, Carlo Aschele, Teseo Stefanini, Cinzia Sani, Emilio Falco, Stefano Berti
BACKGROUND: For the treatment of both primary and metastatic liver tumors, laparoscopic parenchyma-sparing surgery is advocated to reduce postoperative liver failure and facilitate reoperation in the case of recurrence. However, atypical and wedge resections are associated with a higher amount of intraoperative bleeding than are anatomical resections, and such bleeding is known to affect short- and long-term outcomes. Beyond the established role of radiofrequency and microwave ablation in the setting of inoperable liver tumors, the application of thermoablative energy along the plane of the liver surface to be transected results in a zone of coagulative necrosis, possibly minimizing bleeding of the cut liver surface during parenchymal transection...
March 2017: Surgical Endoscopy
Dimitrios Kaparelos, Demetrios Moris, Michalis Kontos, Alexandros Papalampros, Athanasios Petrou, Christos Tsigris, Emmanouil Pikoulis, Nikolaos Kavantzas, Apostolos Papalois, Evangelos Felekouras
PURPOSE: The aim of this study was to compare the feasibility, efficacy and safety of microwave ablation and saline-linked radiofrequency (Aquamantys) in liver resection. METHODS: Sixteen domestic pigs (8 per group) underwent thermoablations. Group A consisted of 8 pigs in which microwave left lateral liver resection was performed. Group B consisted of 8 pigs which underwent left lateral liver resection by the Aquamantys system. After 28 days of close follow-up, the animals were sacrificed in order to study the macroscopic and microscopic findings of each intervention on the liver edge...
March 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
Robert M Eisele
Local ablation of liver tumors matured during the recent years and is now proven to be an effective tool in the treatment of malignant liver lesions. Advances focus on the improvement of local tumor control by technical innovations, individual selection of imaging modalities, more accurate needle placement and the free choice of access to the liver. Considering data found in the current literature for conventional local ablative treatment strategies, virtually no single technology is able to demonstrate an unequivocal superiority...
April 21, 2016: World Journal of Gastroenterology: WJG
K I Ringe, M Panzica, C von Falck
UNLABELLED: The aim of this article is to review the significance of percutaneous thermal ablation in the treatment of bone tumors. We describe available ablation techniques as well as advantages and disadvantages in specific settings. In detail, radiofrequency ablation (RFA), microwave ablation (MWA), laser ablation, high intensity focused ultrasound (HIFU) and cryoablation are presented. In the second part of this review curative and palliative indications for the treatment of benign and malignant bone tumors are discussed...
June 2016: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
Junfeng Zhao, Linxue Qian, Yuan Zu, Ying Wei, Xiangdong Hu
The objective of this study was to explore the value of ultrasound-guided percutaneous microwave thermoablation to treat secondary hyperparathyroidism (SHPT). One hundred and thirty-eight parathyroid glands from 56 patients with SHPT were ablated in this study. All the parathyroid glands were evaluated by real-time contrast-enhanced ultrasound before, during and after ablation. Changes in serum parathyroid hormone (sPTH) levels were measured before treatment and at 1 h, 1 wk, 1 mo and 6 mo after thermoablation treatment...
May 2016: Ultrasound in Medicine & Biology
Baoan Hong, Xin Du, Yuan Zhao, Guowei Chen, Xiaodong Zhang, Ning Zhang, Yong Yang
PURPOSE: A model of in vivo porcine kidneys is used to clarify the characteristics of laparoscopic microwave ablation (MWA) of renal tissue. MATERIALS AND METHODS: Six pigs were utilised for the experiment using 18G water circulating-cooling microwave needles. The operating frequency was 2450 MHz, and the independent variables were power (50-60 W) and time (300-600 s). The kidneys were dissociated laparoscopically and ablated with a single or double needle at different power/time combinations and depths of puncture...
2015: International Journal of Hyperthermia
Françoise Bonichon, Yann Godbert, Afshin Gangi, Xavier Buy, Jean Palussière
Thermal ablation (radiofrequency, microwave, cryosurgery, laser interstitial thermal therapy) is being used more frequently as a local treatment of secondary but also primary cancers and benign lesions. It has a low morbidity and is repeatable. The problem is that computed tomographic scan has limits, and RECIST criteria are not applicable. The objective of this article is to summarize the usefulness and pitfalls of PET/computed tomography in detecting a relapse after thermal ablation as soon as possible.
October 2015: PET Clinics
L P Beyer, B Pregler, C Niessen, M Dollinger, B M Graf, M Müller, H J Schlitt, C Stroszczynski, P Wiggermann
PURPOSE: To evaluate and compare the needle placement accuracy, patient dose, procedural time, complication rate and ablation success of microwave thermoablation using a novel robotic guidance approach and a manual approach. METHODS: We performed a retrospective single-center evaluation of 64 microwave thermoablations of liver tumors in 46 patients (10 female, 36 male, mean age 66 years) between June 2014 and February 2015. Thirty ablations were carried out with manual guidance, while 34 ablations were performed using robotic guidance...
February 2016: International Journal of Computer Assisted Radiology and Surgery
Jijo Paul, Thomas J Vogl, Annamma Chacko
BACKGROUND: Microwave thermoablation (MTA) is a treatment method used to destroy hepatic tumors. OBJECTIVE: To investigate temperature changes during MTA of ex-vivo porcine liver using dual-energy computed tomography (DECT) imaging. METHODS: Three MTA experiments were performed using ex-vivo porcine liver (15 × 15 × 15 cm(3)) and DECT imaging with 80/Sn140 kVp spectral and 0.5-weighted reconstructions. Images were acquired from basic organ temperature to 100 °C with 10 °C difference during microwave heating and cooling phases...
November 2015: Physica Medica: PM
Koichiro Murakami, Shigeyuki Naka, Hisanori Shiomi, Hiroya Akabori, Yoshimasa Kurumi, Shigehiro Morikawa, Tohru Tani
PURPOSE: Percutaneous thermal ablation is used for treating hepatic tumors. Recent advances in laparoscopy and imaging modalities have led to the development of a novel image-guided minimally invasive loco-regional treatment. The aim of this trial was to apply laparoscopic assistance to magnetic resonance (MR) image-guided thermoablation instead of ultrasonography, because of its various advantages. METHODS: Patients with hepatic tumors and liver cirrhosis underwent magnetic resonance (MR) image-guided laparoscopic microwave coagulation therapy using a borescope and endoscopic forceps...
September 2015: Surgery Today
Emmanuel C Mbalisike, Thomas J Vogl, Stefan Zangos, Katrin Eichler, Prakash Balakrishnan, Jijo Paul
OBJECTIVE: To evaluate and compare novel robotic guidance and manual approaches based on procedural accuracy, procedural time, procedural performance, image quality as well as patient dose during image-guided microwave thermoablation. METHOD: The study was prospectively performed between June 2013 and December 2013 using 70 patients. Forty randomly selected patients (group 1) were treated with manual guidance and 30 patients (group 2) were treated using a novel robotic guidance...
February 2015: European Radiology
T Hofmockel, V Plodeck, M Laniado, R-T Hoffmann
Hepatocellular carcinoma (HCC) is one of the most frequent malignancies worldwide. Besides liver transplantation, which is only feasible in few patients and surgical resection, the scope of potential treatment options has considerably expanded in recent years. Thermoablative therapies are now well established in early HCC due to the low rate of complications and short hospital stay. The disadvantage of higher relapse rates compared to surgical resection will be further diminished through technical advances regarding radiofrequency ablation and microwave ablation, as well as growing experience of users and thorough multidisciplinary selection of potential candidates for thermoablative therapy...
July 2014: Der Radiologe
N Molla, N AlMenieir, E Simoneau, M Aljiffry, D Valenti, P Metrakos, L M Boucher, M Hassanain
BACKGROUND: Hepatocellular carcinoma (hcc) is one of the most common causes of cancer-related death worldwide. Overall, liver transplantation and resection are the only available treatments with potential for cure. Various locoregional therapies are widely used to manage patients with advanced hcc or as a bridging therapy for patients with early and intermediate disease. This article reviews and evaluates the role of interventional radiology in the management of such cases by assessing various aspects of each method, such as effect on rates of survival, recurrence, tumour response, and complications...
June 2014: Current Oncology
Katrina F Chu, Damian E Dupuy
Minimally invasive thermal ablation of tumours has become common since the advent of modern imaging. From the ablation of small, unresectable tumours to experimental therapies, percutaneous radiofrequency ablation, microwave ablation, cryoablation and irreversible electroporation have an increasing role in the treatment of solid neoplasms. This Opinion article examines the mechanisms of tumour cell death that are induced by the most common thermoablative techniques and discusses the rapidly developing areas of research in the field, including combinatorial ablation and immunotherapy, synergy with conventional chemotherapy and radiation, and the development of a new ablation modality in irreversible electroporation...
March 2014: Nature Reviews. Cancer
Kristina Imeen Ringe, Frank Wacker, Hans-Jürgen Raatschen
BACKGROUND: Radiofrequency (RFA) and microwave ablation (MWA) are established minimally invasive techniques for treatment of hepatic tumors. PURPOSE: To compare technical success and accuracy of hepatic thermoablation using computed tomography (CT) and magnetic resonance imaging (MRI) acquired 24 h after ablation with regard to evaluation of the post-interventional ablation zone and local tumor recurrence (LTR), and to assess whether additional MRI within 24 h is beneficial...
January 2015: Acta Radiologica
Carlo Gazzera, Paolo Fonio, Riccardo Faletti, Maria Chiara Dotto, Fabio Gobbi, Pierpaolo Donadio, Giovanni Gandini
PURPOSE: This paper discusses the technique and preliminary results of right thoracic paravertebral block (TPVB) for percutaneous thermal ablation of liver tumours. MATERIALS AND METHODS: Between October 2011 and August 2012 we treated 36 lesions (25 hepatocellular carcinoma and 11 metastases) in 30 patients aged 47-85 years (mean 67.5). Patients received ultrasound (US)-guided injection of 7 ml of naropin 0.75 % in T7, T9 and T11 levels, below the costo-vertebral ligament, until we observed an anterior displacement of the parietal pleura...
August 2014: La Radiologia Medica
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