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GCS and Stoke

Jie Gao, Lingbo Kong, Si Liu, Zhiqiao Feng, Hong Shen, Qingquan Liu
OBJECTIVE: To evaluate the clinical efficacy and safety of Xuebijing injection in treatment of sepsis and multiple organ dysfunction syndrome (MODS). METHODS: A prospective multicenter clinical study was conducted. The patients with sepsis, severe sepsis, or MODS admitted to Department of Emergency and Critical Care Medicine of 70 hospitals across the country during 2006 to 2008 were enrolled. All of the patients received the basis treatment of conventional therapy, plus Xuebijing injection of 50-100 mL, 2-3 times a day for 5-7 days, and the dose might be increased in serious cases...
June 2015: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Leonardo Lorente, María M Martín, Pedro Abreu-González, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Marta Riaño-Ruiz, Alejandro Jiménez
OBJECTIVE: Malondialdehyde (MDA) is an end-product formed during lipid peroxidation, due to degradation of cellular membrane phospholipids. MDA is released into extracellular space and finally into the blood; it has been used as an effective biomarker of lipid oxidation. High circulating levels of MDA have been previously described in patients with ischemic stoke than in controls, and an association between circulating MDA levels and neurological functional outcome in patients with ischemic stoke...
2015: PloS One
Wuwei Feng, Gabriela Vasquez, M Fareed K Suri, Kamakshi Lakshminarayan, Adnan I Qureshi
Previous analyses, including the National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stoke Trial, have assessed the clinical treatment efficacy only at single study point, but did not assess efficacy using outcomes collected at multiple time points and incorporate within-patient correlation. The data from the NINDS rt-PA Stroke Trial was analyzed with repeated-measures analysis with generalized estimating equations (GEE) approach using dichotomized outcomes (modified Rankin Scale [mRS], National Institutes of Health Stroke Scale [NIHSS], Barthel Index [BI], and Glasgow Outcome Scale [GOS])...
May 2011: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Carlos V R Brown, Kelli H Foulkrod, Daniel Lopez, John Stokes, Jesus Villareal, Katie Foarde, Eardie Curry, Ben Coopwood
BACKGROUND: Recombinant activated factor VII (rFVIIa) has been associated with decreased blood transfusion requirements in trauma patients. Clinical use has recently been extended to the treatment of coagulopathic patients with traumatic brain injury, and results have been encouraging. However, the cost and possible thromboembolic complications of rFVIIa have been considered barriers to its widespread use. We hypothesize that rFVIIa would provide an effective and cost efficient means of correcting coagulopathy in patients with traumatic brain injury undergoing emergent craniotomy...
February 2010: Journal of Trauma
Patricia Braga, Alicia Ibarra, Isabel Rega, Carlos Ketzoian, Matías Pebet, Liliana Servente, Daniela Benzano
The purpose of this trial was to identify clinical factors and evaluation studies with significant value as mortality predictors in patients suffering an acute stroke. One hundred forty-eight consecutive patients hospitalized at the Hospital de Clínicas, Montevideo, with a clinical diagnosis of stroke were studied: 85 had ischemic strokes and 63 presented with intracerebral hemorrhages. The potentially predictive variables (past medical history, clinical assessment, neuroimaging, biochemical analysis) were evaluated within the first 24 hours of admission; patient follow-up was performed until they left the hospital or died...
January 2002: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Gregg Rosner
Brain injury, specifically TBI, is a common occurrence in our society, with devastating physical, emotional, social and economic costs. Injury not only occurs on initial impact, but also develops slowly over ensuing hours or days. TBI poses unique challenges and requires special care, especially with airway management and ventilatory treatment. Serial assessment, particularly of the GCS and pupillary changes, is vital in continuing to monitor patient status. All treatment associated with the TBI patient is aimed at restoring CPP and allowing oxygenated blood to reach injured brain tissues...
March 2003: JEMS: a Journal of Emergency Medical Services
A H Rhea, D Howell, C S Stokes
No abstract text is available yet for this article.
March 1997: Journal of the South Carolina Medical Association
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