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https://www.readbyqxmd.com/read/28626099/-a-cross-sectional-study-on-the-correlation-between-mri-signal-for-ipfp-and-knee-osteoarthritis
#1
Song Wu, Hongliang Ba, Jinshen He, Yunjie Liao
To investigate the correlation between MRI signal for infrapatellar fat pad (IPFP) and pathological changes in knee osteoarthritis (KOA), and to analyze the role of IPFP in the development of knee osteoarthritis.
 Methods: A total of 114 subjects (without special knee disease) were enrolled for this study. The intensity of MRI signal for IPFP was determined by fat-suppressed proton-density-weighted turbospin-echo magnetic resonance imaging. Based on the cartilage defects and osteophytes of knee joint, the subjects were divided into a KOA group and a control group...
May 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28602782/associations-between-serum-ghrelin-and-knee-symptoms-joint-structures-and-cartilage-or-bone-biomarkers-in-patients-with-knee-osteoarthritis
#2
J Wu, K Wang, J Xu, G Ruan, Q Zhu, J Cai, J Ren, S Zheng, Z Zhu, P Otahal, C Ding
OBJECTIVE: The roles of ghrelin in knee osteoarthritis (OA) are unclear. This study aimed to examine cross-sectional associations of ghrelin with knee symptoms, joint structures and cartilage or bone biomarkers in patients with knee OA. METHODS: This study included 146 patients with symptomatic knee OA. Serum levels of ghrelin and cartilage or bone biomarkers including cartilage oligomeric matrix protein (COMP), cross linked C-telopeptide of type I collagen (CTXI), cross linked N-telopeptide of type I collagen (NTXI), N-terminal procollagen III propeptide (PIIINP), and matrix metalloproteinase (MMP)-3, 10, 13 were measured using Enzyme-linked immunosorbent assay (ELISA)...
June 15, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28602535/periarticular-injections-in-knee-and-hip-arthroplasty-where-and-what-to-inject
#3
Jeremy A Ross, Anna C Greenwood, Phillip Sasser, William A Jiranek
BACKGROUND: Periarticular injections have become a valuable adjunct to multimodal pain control regimens after knee and hip arthroplasties. Injection techniques vary greatly among surgeons with little standardization of practice. METHODS: We performed an extensive literature search to determine where nociceptive pain fibers are located in the hip and the knee and also to explore the pharmacology of periarticular cocktail ingredients. RESULTS: Large concentrations of nociceptors are present throughout the various tissues of the knee joint with elevated concentrations in the infrapatellar fat pad, fibrous capsule, ligament insertions, periosteum, subchondral bone, and lateral retinaculum...
May 11, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28601257/commentary-on-co-culture-of-infrapatellar-fat-pad-derived-mscs-and-articular-chondrocytes-in-plasma-clot-for-cartilage-tissue-engineering
#4
https://www.readbyqxmd.com/read/28585993/a-modified-lateral-approach-for-total-knee-replacement-in-type-2-valgus-deformity
#5
Matthias Aurich, Mark Lenz, Norman Best
Total knee replacement for patients with osteoarthritis and valgus deformity remains challenging, with soft tissue balance often difficult to achieve. Most orthopedic surgeons use the medial parapatellar approach for total knee replacement. However, the lateral approach described in this case allows direct access to the pathology. The valgus deformity is corrected by using a modified lateral parapatellar arthrotomy with a staged and gradual release of the contracted lateral capsuloligamentous structures and the iliotibial tract...
June 6, 2017: Orthopedics
https://www.readbyqxmd.com/read/28573437/oblique-incisions-in-hamstring-tendon-harvesting-reduce-iatrogenic-injuries-to-the-infrapatellar-branch-of-the-saphenous-nerve
#6
Brandon Michael Henry, Krzysztof A Tomaszewski, Przemysław A Pękala, Matthew J Graves, Jakub R Pękala, Beatrice Sanna, Ewa Mizia
PURPOSE: Iatrogenic injury to the infrapatellar branch of the saphenous nerve (IPBSN) is associated with many surgical interventions to the medial aspect of the knee, such as anterior cruciate ligament (ACL) reconstruction. Different types of surgical incisions during hamstring tendon harvesting for ACL reconstruction are related to a variable risk of IPBSN injury. This study aimed to evaluate the risk of iatrogenic IPBSN injury during hamstring tendon harvesting for ACL reconstruction with different incision techniques over the pes anserinus...
June 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28572469/magnetic-resonance-imaging-mri-of-the-knee-as-an-outcome-measure-in-juvenile-idiopathic-arthritis-an-omeract-reliability-study-on-mri-scales
#7
Robert Hemke, Nikolay Tzaribachev, Charlotte M Nusman, Marion A J van Rossum, Mario Maas, Andrea S Doria
OBJECTIVE: There is increasing evidence that early therapeutic intervention improves longterm joint outcome in juvenile idiopathic arthritis (JIA). Given the existence of highly effective treatments, there is an urgent need for reliable and accurate measures of disease activity and joint damage in JIA. Our objective was to assess the reliability of 2 magnetic resonance imaging (MRI) scoring methods: the Juvenile Arthritis MRI Scoring (JAMRIS) system and the International Prophylaxis Study Group (IPSG) consensus score, for evaluating disease status of the knee in patients with JIA...
June 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28556569/matrilin-3-co-delivery-with-adipose-derived-mesenchymal-stem-cells-promotes-articular-cartilage-regeneration-in-a-rat-osteochondral-defect-model
#8
Manjunatha S Muttigi, ByoungJu Kim, Bogyu Choi, Arai Yoshie, Hemant Kumar, Inbo Han, Hansoo Park, Soo-Hong Lee
Matrilin-3 is an essential extracellular matrix (ECM) component present only in cartilaginous tissues. Matrilin-3 exerts chondro-protective effects by regulating an anti-inflammatory function and ECM components. We hypothesized that the co-delivery of matrilin-3 with infrapatellar adipose tissue-derived mesenchymal stem cells (Ad-MSCs) may enhance articular cartilage regeneration. Matrilin-3 treatment of Ad-MSCs in serum-free media induced collagen II and aggrecan expression, andmatrilin-3 in chondrogenic media (CM) also enhanced in vitro chondrogenic differentiation...
May 29, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28551203/single-limb-landing-biomechanics-are-altered-and-patellar-tendinopathy-related-pain-is-reduced-with-acute-infrapatellar-strap-application
#9
Adam B Rosen, Jupil Ko, Cathleen N Brown
BACKGROUND: Patellar tendinopathy, a common condition of the knee, is often treated with patellar tendon straps to control pain during dynamic activity. Little is known regarding their effect on pain, landing kinematics and kinetics with their application. The purpose of this study was to determine if patellar tendon straps influenced pain, kinematics at landing and ground reaction forces in individuals with patellar tendinopathy versus healthy controls. METHODS: Thirty participants with patellar tendinopathy and 30 controls participated...
May 24, 2017: Knee
https://www.readbyqxmd.com/read/28514510/injury-to-the-infrapatellar-branch-of-the-saphenous-nerve-during-tendon-graft-harvesting-for-knee-ligament-reconstruction-an-ultrasound-simulation-study
#10
Przemysław A Pękala, Ewa Miza, Brandon Michael Henry, Patrick Popieluszko, Marios Loukas, Krzysztof A Tomaszewski
INTRODUCTION: The clinical anatomy of the infrapatellar branch of the saphenous nerve (IPBSN) is of particular importance during operations in the area of the knee, especially when material for anterior cruciate ligament reconstruction is harvested. The nerve can easily be injured during the harvesting procedure, leading to postoperative complications that reduce quality of life. Three different skin incisions are commonly used during hamstring tendon harvesting: horizontal, vertical, and oblique...
May 17, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28479049/co-culture-of-infrapatellar-fat-pad-derived-mesenchymal-stromal-cells-and-articular-chondrocytes-in-plasma-clot-for-cartilage-tissue-engineering
#11
Aditya Arora, M Sriram, Anjaney Kothari, Dhirendra S Katti
BACKGROUND: Cell source plays a deterministic role in defining the outcome of a cell-based cartilage regenerative therapy and its clinical translational ability. Recent efforts in the direction of co-culture of two or more cell types attempt to combine the advantages of constituent cell types and negate their demerits. METHODS: We examined the potential of co-culture of infrapatellar fat pad-derived mesenchymal stromal cells (IFP MSCs) and articular chondrocytes (ACs) in plasma clots in terms of their ratios and culture formats for cartilage tissue engineering...
July 2017: Cytotherapy
https://www.readbyqxmd.com/read/28463545/meniscal-tissue-engineering-using-aligned-collagen-fibrous-scaffolds-comparison-of-different-human-cell-sources
#12
Jihye Baek, Sujata Sovani, Wonchul Choi, Sungho Jin, Shawn P Grogan, Darryl D D'Lima
Hydrogel and electrospun scaffold materials support cell attachment and neotissue development and can be tuned to structurally and mechanically resemble native extracellular matrix by altering either electrospun fiber or hydrogel properties. In this study, we examined meniscus tissue generation from different human cell sources including meniscus cells derived from vascular and avascular regions, human bone marrow-derived mesenchymal stem cells, synovial cells, and cells from the infrapatellar fat pad (IPFP)...
June 13, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28431586/expression-of-calcitonin-gene-related-peptide-in-the-infrapatellar-fat-pad-in-knee-osteoarthritis-patients
#13
Jun Aikawa, Kentaro Uchida, Shotaro Takano, Gen Inoue, Atsushi Minatani, Masayuki Miyagi, Dai Iwase, Hiroyuki Sekiguchi, Manabu Mukai, Masashi Takaso
BACKGROUND: The infrapatellar fat pad (IPFP) has been implicated as a possible source of osteoarthritis (OA) development and knee pain due to the production of inflammatory mediators and the existence of nerve fibers within this structure. Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that is localized to joint tissues and has recently been implicated in the development of knee OA and OA pain. To date, however, the expression levels of CGRP in the IPFP of human knee OA patients have not been examined...
April 21, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28404457/nerve-injury-during-anterior-cruciate-ligament-reconstruction-a-comparison-between-patellar-and-hamstring-tendon-grafts-harvest
#14
Barak Haviv, Shlomo Bronak, Ehud Rath, Mustafa Yassin
BACKGROUND: Tendon harvesting for anterior cruciate ligament reconstruction often injures sensory branches of the saphenous nerve. The reports on the prevalence of these injuries are scarce, while the implications on patient satisfaction are not known. Our objective was to compare the prevalence of sensory nerve injuries in patellar to hamstring autograft harvesting for anterior cruciate ligament reconstructions and follow up their postoperative course. METHODS: Between 2012 and 2014, patients who had a primary anterior cruciate ligament reconstruction with bone patellar tendon bone or hamstring autografts were included (n=94)...
April 9, 2017: Knee
https://www.readbyqxmd.com/read/28378501/anterior-cruciate-ligament-reconstruction-does-not-induce-further-gamma-loop-abnormalities-on-the-intact-side-of-the-quadriceps-femoris-a-longitudinal-study
#15
Y Konishi
This study aimed to investigate the effect of surgery on the gamma loop of the quadriceps on the side with an intact knee in patients with anterior cruciate ligament (ACL) injuries. We compared longitudinally the response of alpha motor neurons to vibration stimulation of the quadriceps on the side with an intact knee before and after ACL reconstruction. To evaluate alpha motor neuron response, we measured the maximal knee extension strength and integrated electromyography of the vastus medialis, vastus lateralis, and rectus femoris...
April 4, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28376759/prognostic-value-of-mri-in-arthroscopic-treatment-of-chronic-patellar-tendinopathy-a-prospective-cohort-study
#16
Peter Ogon, Kaywan Izadpanah, Helge Eberbach, Gernot Lang, Norbert P Südkamp, Dirk Maier
BACKGROUND: To date, prognostic outcome factors for patients undergoing arthroscopic treatment due to chronic patellar tendinopathy (PT) are lacking. The purpose of this study was to investigate whether preoperatively assessed MRI parameters might be of prognostic value for prediction of functional outcome and return to sports in arthroscopic treatment of chronic PT. METHODS: A prospective cohort study was conducted including 30 cases (4 female and 24 male competitive athletes) undergoing arthroscopic patellar release (APR) due to chronic PT...
April 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28361218/intramedullary-nailing-of-tibial-shaft-fractures-in-the-semi-extended-position-using-a-suprapatellar-portal-technique
#17
REVIEW
Boris A Zelle
Intramedullary nail fixation remains the standard treatment for displaced tibial shaft fractures. Establishing an appropriate starting point remains a crucial step in the surgical procedure. Tibial nailing using an infrapatellar starting point with the knee flexed over a radiolucent triangle has been established as a widely-used standard technique. Tibial nail insertion with the knee in the semi-extended position was introduced with the goal to counteract post-operative procurvatum deformities that frequently have been reported as a common problem in proximal third tibial shaft fractures...
March 30, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28336454/cryoneurolysis-to-treat-the-pain-and-symptoms-of-knee-osteoarthritis-a-multicenter-randomized-double-blind-sham-controlled-trial
#18
R Radnovich, D Scott, A T Patel, R Olson, V Dasa, N Segal, N E Lane, K Shrock, J Naranjo, K Darr, R Surowitz, J Choo, A Valadie, R Harrell, N Wei, S Metyas
OBJECTIVE: Evaluate the efficacy and safety/tolerability of cryoneurolysis for reduction of pain and symptoms associated with knee osteoarthritis (OA). DESIGN: Randomized, double-blind, sham-controlled, multicenter trial with a 6-month follow-up in patients with mild-to-moderate knee OA. Patients were randomized 2:1 to cryoneurolysis targeting the infrapatellar branch of the saphenous nerve (IPBSN) or sham treatment. The primary endpoint was the change from baseline to Day 30 in the Western Ontario and McMaster Osteoarthritis Index (WOMAC) pain score adjusted by the baseline score and site...
March 20, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28334450/short-term-effects-of-arthrotomy-with-and-without-infrapatellar-fat-pad-resection-on-the-normal-canine-stifle
#19
Yukihiro Fujita, Tetsuya Nakajo, Makoto Muto
OBJECTIVE: To investigate the short-term effects of infrapatellar fat pad (IFP) resection in normal dogs. STUDY DESIGN: Experimental in vivo study. ANIMALS: Five normal adult female beagle dogs. METHODS: The IFP was resected via arthrotomy in the left stifle joint (experimental side) while the right stifle underwent arthrotomy alone (sham side). An orthopedic examination was performed every week for 4 weeks and synovial fluid was analyzed before and 4 weeks after the procedure...
March 23, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28327683/infra-patellar-branch-of-saphenous-nerve-injury-during-hamstring-graft%C3%A2-harvest-vertical-versus-oblique-incisions
#20
A Joshi, N Kayasth, S Shrestha, B R Kc
BACKGROUND: Autologous hamstring grafts are commonly used for anterior cruciate ligament reconstruction. The injury of infrapatellar branch of saphenous nerve is one of the concerns leading to various pattern of sensory loss in the operated leg. An oblique incision to harvest the graft has been reported to be better than the vertical one.The aim of this study was to compare the incidence, recovery of nerve injury and final outcome in patients with hamstring harvest of vertical or oblique incision...
September 2016: Journal of Nepal Health Research Council
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