keyword
https://read.qxmd.com/read/38656673/correction-relationship-between-the-change-in-infrapatellar-fat-pad-thickness-assessed-using-ultrasonography-and-anterior-knee-pain-on-squatting-after-anterior-cruciate-ligament-reconstruction
#1
https://read.qxmd.com/read/38654799/combination-of-pulmonary-tractotomy-and-free-subcutaneous-fat-pad-coverage-for-iatrogenic-lung-injury-caused-by-chest-tube-insertion
#2
Eito Niman, Kenji Takahashi
Iatrogenic lung injury caused by chest tube insertion is a potential complication that requires careful attention, and thoracic surgeons should be knowledgeable about the appropriate management strategies if complications arise. This report describes a successful procedure for treating an iatrogenic lung injury. An 80-year-old Japanese man with severe emphysema complaining of breathlessness was diagnosed with a right secondary pneumothorax. Computed tomography revealed moderate adhesions in the thoracic cavity...
March 2024: Curēus
https://read.qxmd.com/read/38649202/electroacupuncture-improves-peripheral-neuropathy-by-up-regulating-sirt1-pgc-1%C3%AE-tfam-pathway-in-type-2-diabetes-rats-with-peripheral-neuropathy
#3
JOURNAL ARTICLE
Chong-Xi Yuan, Xuan Wang, Zhi Yu, Xiao-Yang Lian, Bin Xu
OBJECTIVES: To observe the effect of electroacupuncture (EA) on activation of silent information regulator 1 (Sirt1)/peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α)/mitochondrial transcription factor A (TFAM) pathway in type 2 diabetes (T2DM) rats with peripheral neuropathy (DPN) , so as to explore its possible mechanisms underlying improvement of DPN. METHODS: Thirty male SD rats were randomly divided into blank control group ( n =8) and DPN model group ( n =22) which were further divided into model group ( n =8) and EA group ( n =8) after successful modeling...
April 25, 2024: Zhen Ci Yan Jiu, Acupuncture Research
https://read.qxmd.com/read/38649126/partial-cardiac-denervation-to-prevent-postoperative-atrial-fibrillation-after-coronary-artery-bypass-grafting-pcad-poaf-study-protocol-for-a-randomized-controlled-trial
#4
JOURNAL ARTICLE
Ziang Yang, Xieraili Tiemuerniyazi, Shengkang Huang, Yangwu Song, Fei Xu, Wei Feng
Postoperative atrial fibrillation (POAF) is commonly seen in patients undergoing coronary artery bypass grafting (CABG), increasing the risk of morbidity, mortality and hospital expenses. This study is aimed to evaluate the effect of partial cardiac denervation, which is achieved by cutting off the ligament of Marshall and resecting the fat pad along the Waterston groove, on the prevention of POAF after CABG. Patients planned for CABG at our center will be screened for eligibility for this study. A total of 430 patients will be randomized into intervention (partial cardiac denervation) group and control group...
April 20, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38644540/white-adipose-tissue-a-novel-antirheumatic-target-clues-from-its-secretory-capability-and-adipectomy-based-therapy
#5
JOURNAL ARTICLE
Peng Ye, Qi-Hai Wang, Wen-Ye Kong, Chun-Sheng Liu, Dan-Dan Wang, Opeyemi Joshua Olatunji, Yan Li, Jian Zuo
BACKGROUND AND PURPOSE: White adipose tissue (WAT) is involved in rheumatoid arthritis (RA). This study explored its potential as an antirheumatic target. EXPERIMENTAL APPROACH: WAT status of healthy and adjuvant-induced arthritis (AIA) rats were compared. The contribution of WAT to RA pathology was evaluated by pre-adipocyte transplant experiments and by dissecting perirenal fat pads of AIA rats. The impact of RA on WAT was investigated by culturing pre-adipocytes...
April 21, 2024: British Journal of Pharmacology
https://read.qxmd.com/read/38642652/carry-over-effects-of-maternal-late-gestation-heat-stress-on-granddaughter-s-growth-and-mammary-gland-development
#6
JOURNAL ARTICLE
Grace A Larsen, Jimena Laporta
Maternal (F0 ) exposure to late-gestation heat stress reduces their daughter's (F1 ) mammary gland fat pad mass (FP), parenchyma (PAR) mass, and epithelial cell proliferation when evaluated at birth and weaning, and go on to produce less milk in their first lactation. Herein, we investigated the effect of maternal late-gestation heat stress on whole-body growth and mammary development of their granddaughters (F2 ). Multiparous F0 cows had access to heat abatement (n = 41, shade, and active cooling via fans and water soakers) or not (n = 41, shade only) for the last 56 d of gestation during a subtropical summer...
April 18, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38638114/excellent-10-year-survivorship-of-robotic-arm-assisted-unicompartmental-knee-arthroplasty
#7
JOURNAL ARTICLE
Martin Roche, Rushabh M Vakharia, Tsun Law, Hugo C Rodriguez, Kevin L Mekkawy, Nipun Sodhi, Jeremy A Dubin, Daniel Hameed, Michael A Mont
INTRODUCTION: Robotic-arm-assisted unicompartmental knee arthroplasty (UKA) is an excellent solution for patients suffering from single-compartment knee arthritis. While outcomes tend to be favorable for UKAs, revision operations, commonly due to component malpositioning and malalignment resulting in accelerated wear, are a major concern. Intraoperative technologies, such as robotic assistance, can help better ensure that implants are positioned based on a patient's specific anatomy and mechanical physiology...
September 2024: Journal of Orthopaedics
https://read.qxmd.com/read/38627635/effect-of-weight-loss-on-knee-joint-synovitis-over-48-months-and-mediation-by-subcutaneous-fat-around-the-knee-data-from-the-osteoarthritis-initiative
#8
JOURNAL ARTICLE
Maximilian T Löffler, Chotigar Ngarmsrikam, Paula Giesler, Gabby B Joseph, Zehra Akkaya, John A Lynch, Nancy E Lane, Michael Nevitt, Charles E McCulloch, Thomas M Link
BACKGROUND: Obesity influences the development of osteoarthritis via low-grade inflammation. Progression of local inflammation (= synovitis) increased with weight gain in overweight and obese women compared to stable weight. Synovitis could be associated with subcutaneous fat (SCF) around the knee. Purpose of the study was to investigate the effect of weight loss on synovitis progression and to assess whether SCF around the knee mediates the relationship between weight loss and synovitis progression...
April 17, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38623267/metastatic-pericardial-mass-and-cardiophrenic-lymph-nodes-resection-in-ovarian-cancer
#9
JOURNAL ARTICLE
Lingling Xie, Shaodan Lin, Haibo Zhao, Zhongqiu Lin, Huaiwu Lu
INTRODUCTION: Epithelial Ovarian cancer most commonly presents at advanced stages with extra-abdominal disease metastasis. Notably, enlarged cardiophrenic lymph nodes are found in 10.5-62 % of patients with advanced ovarian cancer. However, the safety and feasibility of cardiophrenic lymph nodes dissection as a component of debulking surgery remains controversial (Acs et al., 2022, Agusti et al., 2024). CASE/METHODS: We present a surgical video demonstrating the technique of bulky pericardial mass and metastatic cardiophrenic lymph nodes resection by transdiaphragmatic approach in advanced ovarian cancer...
June 2024: Gynecologic Oncology Reports
https://read.qxmd.com/read/38608939/plasma-and-milk-metabolomics-profiles-in-dairy-cows-with-subclinical-and-clinical-ketosis
#10
JOURNAL ARTICLE
Yan Huang, Bihong Zhang, John Mauck, Juan J Loor, Bo Wei, Bingyu Shen, Yazhou Wang, Chenxu Zhao, Xiaoyan Zhu, Jianguo Wang
Ketosis, a commonly observed energy metabolism disorder in dairy cows during the peripartal period, is distinguished by increased concentrations of β-hydroxybutyrate (BHB) in blood. This condition has a negative impact on milk production and quality, causing financial losses. An untargeted metabolomics approach was performed on plasma samples from cows between 5 and 7 DIM diagnosed as controls (CON, BHB <1.2 mM, n = 30), subclinically ketotic (SCK, 1.2 < BHB <3.0 mM, n = 30), or clinically ketotic (CK, BHB >3...
April 10, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38597716/buccal-fat-advancement-transposition-flap-for-reconstruction-of-midface-volume-defects
#11
JOURNAL ARTICLE
Seth J Davis, Christopher Park, Isaac T Shipchandler, Abraham Abdulhak, Dominic Vernon, Hui Bae Lee, Avinash V Mantravadi, Jonathan Ting, Taha Z Shipchandler
Background: The buccal fat pad (BFP) has previously been utilized for repair of various defects of the head and neck. Objectives: We explore the utility of a pedicled buccal fat advancement-transposition (BFAT) flap in various forms of midface reconstruction through a variety of surgical approaches and characterize its volume and axial reach in human anatomic specimens. Methods: Ten adult full-head human anatomic specimens were dissected, and a single surgical case demonstrating the use of a BFAT flap is described...
April 8, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38592504/coadministration-of-doxorubicin-with-vitamin-d3-lactobacillus-acidophilus-and-lactobacillus-casei-in-the-4t1-mouse-model-of-breast-cancer-anticancer-and-enteroprotective-effects
#12
JOURNAL ARTICLE
Mohammad Ali Mirzadeh, Majid Eslami, Ali Ghanbari, Sam Zarbakhsh, Sedighe Yosefi, Abbas Pakdel
The use of doxorubicin (Dox) in the treatment of breast cancer negatively affects the intestines and other tissues. Many studies have proven that probiotics and vitamin D3 have antitumor and intestinal tissue-protecting properties. To achieve effectiveness and minimize side effects, the current study aims to administer Dox together with probiotics (Lactobacillus acidophilus and Lactobacillus casei) and vitamin D3. Forty-two female BALB/c inbred mice were divided into six groups: Group 1 (Control), Group 2 (Dox), Group 3 (Dox and probiotics), Group 4 (Dox and vitamin D3), Group 5 (Dox, probiotics, and vitamin D3), and Group 6 (probiotics and vitamin D3)...
April 9, 2024: Medical Oncology
https://read.qxmd.com/read/38592107/adverse-events-and-clinical-correlates-in-asian-patients-with-atrial-fibrillation-and-diabetes-mellitus-a-report-from-asia-pacific-heart-rhythm-society-atrial-fibrillation-registry
#13
JOURNAL ARTICLE
Tommaso Bucci, Katarzyna Nabrdalik, Alena Shantsila, Giulio Francesco Romiti, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Hung-Fat Tse, Marco Proietti, Tze-Fan Chao, Gregory Y H Lip, Asia-Pacific Heart Rhythm Society Atrial Fibrillation Registry Investigators
Aims. To evaluate the adverse events (and its clinical correlates) in a large prospective cohort of Asian patients with atrial fibrillation (AF) and diabetes mellitus (DM). Material and Methods. We recruited patients with atrial fibrillation (AF) from the Asia-Pacific Heart Rhythm Society (APHRS) AF Registry and included those for whom the diabetic mellitus (DM) status was known. We used Cox-regression analysis to assess the 1-year risk of all-cause death, thromboembolic events, acute coronary syndrome, heart failure and major bleeding...
February 23, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38590580/role-of-crosstalk-between-synovial-cells-and-chondrocytes-in-osteoarthritis-review
#14
REVIEW
Baisen Chen, Yuyu Sun, Guanhua Xu, Jiawei Jiang, Wenhao Zhang, Chunshuai Wu, Pengfei Xue, Zhiming Cui
Osteoarthritis (OA) is a low-grade, nonspecific inflammatory disease that affects the entire joint. This condition is characterized by synovitis, cartilage erosion, subchondral bone defects, and subpatellar fat pad damage. There is mounting evidence demonstrating the significance of crosstalk between synovitis and cartilage destruction in the development of OA. To comprehensively explore the phenotypic alterations of synovitis and cartilage destruction, it is important to elucidate the crosstalk mechanisms between chondrocytes and synovial cells...
May 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38589452/heat-shock-factor-1-inhibition-enhances-the-effects-of-modulated-electro-hyperthermia-in-a-triple-negative-breast-cancer-mouse-model
#15
JOURNAL ARTICLE
Pedro H L Viana, Csaba A Schvarcz, Lea O Danics, Balázs Besztercei, Kenan Aloss, Syeda M Z Bokhari, Nino Giunashvili, Dániel Bócsi, Zoltán Koós, Zoltán Benyó, Péter Hamar
Female breast cancer is the most diagnosed cancer worldwide. Triple negative breast cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted therapy. Modulated electro-hyperthermia (mEHT) is a non-invasive complementary cancer therapy using an electromagnetic field generated by amplitude modulated 13.56 MHz frequency that induces tumor cell destruction. However, we have demonstrated a strong induction of the heat shock response (HSR) by mEHT, which can result in thermotolerance...
April 8, 2024: Scientific Reports
https://read.qxmd.com/read/38571774/multislice-computed-tomography-demonstrating-mental-nerve-paresthesia-caused-by-periapical-infection-a-case-report
#16
Yong-Min Kim, Ho-Keun Choi, Jo-Eun Kim, Jeong-Joon Han, Kyung-Hoe Huh
Components derived from an infected lesion within the bone can spread through various passages in the mandible, particularly via the mental foramen. Radiologically, the spread of infection is typically nonspecific and challenging to characterize; however, multislice computed tomography (MSCT) can effectively detect pathological changes in soft tissues and the bone marrow space. This report describes the case of a 55-year-old woman who experienced mental nerve paresthesia due to a periapical infection of the right mandibular second premolar...
March 2024: Imaging Science in Dentistry
https://read.qxmd.com/read/38561081/impacts-of-the-vegetable-urtica-dioica-on-the-intestinal-t-and-b-cell-phenotype-and-macronutrient-absorption-in-c57bl-6j-mice-with-diet-induced-obesity
#17
JOURNAL ARTICLE
Si Fan, Samnhita Raychaundhuri, Opeyemi Ogedengbe, Victor Moronge, Diana N Obanda
In two previous studies, we showed that supplementing a high-fat (HF) diet with 9% w/w U.dioica protects against fat accumulation, insulin resistance, and dysbiosis. This follow up study in C57BL6/J mice aimed at testing: (i) the efficacy of the vegetable at lower doses; 9%, 4% and 2%, (ii) the impact on intestinal T and B cell phenotype and secretions, (iii) impact on fat and glucose absorption during excess nutrient provision.At all doses, the vegetable attenuated HF diet induced fat accumulation in the mesenteric, perirenal, retroperitoneal fat pads and liver but not the epididymal fat pad...
March 30, 2024: Journal of Nutritional Biochemistry
https://read.qxmd.com/read/38550742/an-uncommon-cause-of-sub-acute-intestinal-obstruction-in-young-adult-wilkie-s-syndrome
#18
Kala Shrestha, Niranjan Thapa, Sunil Basukala, Manisha Acharya, Bibek Lama Bhulan, Kaushal Kumar Singh, Oshan Shrestha, Kabita Chaudhary, Milan Kumar Neupane
ABSTRACT: Superior mesenteric artery (SMA) syndrome, also known as Wilkie's syndrome, is a rare disease presenting as an acute abdomen. It has a clinical presentation similar to intestinal obstruction and is often missed during diagnosis. Reduced weight leading to loss of fat pad between SMA and aorta is the main pathophysiology. Diagnosis is made through barium meal and CT scan. Conservative management remains the treatment of choice; however, surgery is opted for in refractory cases...
April 2024: Clinical Case Reports
https://read.qxmd.com/read/38549837/ultrasound-assessment-of-the-infrapatellar-fat-pad-can-detect-hoffa-synovitis-in-patients-following-anterior-cruciate-ligament-reconstruction-a-pilot-study
#19
JOURNAL ARTICLE
M Fagan, R Fajardo, C Grozier, T R Jildeh, M Lissy, M S Harkey
INTRODUCTION: Osteoarthritis (OA) commonly occurs following anterior cruciate ligament reconstruction (ACLR), affecting over 50 % of patients within 10-15 years post-ACLR. The Hoffa-synovitis of the infrapatellar fat pad (IPFP) has been implicated as a major contributor to OA pathogenesis. While MRI is typically used to evaluate the IPFP, it is cost-prohibitive for routine screening. This study aimed to validate ultrasound as an alternative for detecting IPFP Hoffa-synovitis in participants post-ACLR...
March 2024: Osteoarthr Imaging
https://read.qxmd.com/read/38547763/ros-mediated-cu-fe-cn-5-no-nanoparticles-for-triple-negative-breast-cancer-a-detailed-study-in-preclinical-mouse-model
#20
JOURNAL ARTICLE
Sanchita Tripathy, Shagufta Haque, Swapnali Londhe, Sourav Das, Caroline Celine Norbert, Yogesh Chandra, Bojja Sreedhar, Chitta Ranjan Patra
Triple negative breast cancer (TNBC) is an aggressive form of tumor, more prevalent in younger women resulting in poor survival rate (2nd in cancer deaths) because of its asymptomatic existence. The most popular and convenient approach for the treatment of TNBC is chemotherapy which is associated with several limitations. Considering the importance of nanotechnology in health care system, in the present manuscript, we have designed and developed a simple, efficient, cost effective, and ecofriendly method for the synthesis of copper nitroprusside analogue nanoparticles (Cu[Fe(CN)5 NO] which is abbreviated as CuNPANP that may be the potential anti-cancer nanomedicine for the treatment of TNBC...
March 21, 2024: Biomater Adv
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