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Odontogenic cyst

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https://www.readbyqxmd.com/read/29768520/clinical-and-immunohistochemical-study-of-melanotic-neuroectodermal-tumor-of-infancy-in-the-maxilla
#1
Hellen Bandeira de Pontes Santos, Aníbal Henrique Barbosa de Luna, Pedro Everton Marques Goes, Alexander Tadeu Sverzut, Cassiano Francisco Weege Nonaka, Pollianna Muniz Alves
Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. The presumptive diagnoses were dentigerous cyst, adenomatoid odontogenic tumor, melanotic neuroectodermal tumor of infancy and rhabdomyosarcoma, and an incisional biopsy was performed...
May 14, 2018: Einstein
https://www.readbyqxmd.com/read/29745448/early-development-of-the-human-dentition-revisited
#2
REVIEW
Maria Hovorakova, Herve Lesot, Miroslav Peterka, Renata Peterkova
In this review, classical data on the early steps in human odontogenesis are summarized and updated with specific insights into the development of the upper and lower embryonic jaws to help in understanding some oral pathologies. The initial step of human odontogenesis is classically characterized by two parallel horseshoe-shaped epithelial laminae. These originate from the oral epithelium and an ingrowth into the jaw mesenchyme: the internal dental lamina gives rise to deciduous tooth primordia, while the external vestibular lamina represents the developmental base of the oral vestibule...
May 10, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29738629/calcifying-odontogenic-cyst-dentinogenic-ghost-cell-tumor-and-ghost-cell-odontogenic-carcinoma-a-systematic-review
#3
REVIEW
José Alcides Almeida de Arruda, João Luiz Gomes Carneiro Monteiro, Lucas Guimarães Abreu, Leni Verônica de Oliveira Silva, Lauren Frenzel Schuch, Mariana Saturnino de Noronha, Gerhilde Callou, Amália Moreno, Ricardo Alves Mesquita
BACKGROUND: The aim of this study was to integrate the available data published on calcifying odontogenic cyst (COC), dentinogenic ghost cell tumor (DGCT) and ghost cell odontogenic carcinomas (GCOC) into a comprehensive analysis of their clinicoradiological features, treatment and recurrence. MATERIALS AND METHODS: An electronic search with no publication date restriction was undertaken in October 2017 in the following databases: PubMed, Medline Ovid, Web of Science and Scopus...
May 8, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29731583/dentinogenic-ghost-cell-tumor-tumor-in-the-garb-of-a-cyst
#4
Vaishali Korranne, Yash Merchant, Samir Joshi, Rajshekhar Halli
The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm that mimics several inflammatory/reactive lesions of the gingiva or odontogenic cysts. The confirmatory diagnosis of this rare lesion can only be made with histopathological examination. Routine staining reveals features of a "mixed" tumor as ghost cells with calcification, dysplastic dentin and islands of epithelium in rosette pattern in mature connective tissue are visible. The case report describes an asymptomatic growth in the maxillary gingiva of a young patient that was incidentally diagnosed as a DGCT after biopsy...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29731577/expression-of-ki-67-in-odontogenic-cysts-a-comparative-study-between-odontogenic-keratocysts-radicular-cysts-and-dentigerous-cysts
#5
Tapan G Modi, Monali Chalishazar, Malay Kumar
Introduction and Objectives: Odontogenic cysts are the most common cysts of the jaws and are formed from the remnants of the odontogenic apparatus. Among these odontogenic cysts, radicular cysts (RCs) (about 60% of all diagnosed jaw cysts), dentigerous cysts (DCs) (16.6% of all jaw cysts) and odontogenic keratocysts (OKCs) (11.2% of all developmental odontogenic cysts) are the most common. The behavior of any lesion is generally reflected by its growth potential. Growth potential is determined by measuring the cell proliferative activity...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29721233/dentigerous-cyst-with-parietal-and-intracystic-calcifications-a-case-report-and-literature-review
#6
Jordi Borrás-Ferreres, Alba Sánchez-Torres, José-Manuel Aguirre-Urizar, Cosme Gay-Escoda
Background: Dentigerous cyst appears surrounding the crown of an included tooth. On the radiographic exam, a radiolucent rounded well-defined lesion can be observed. Material and Methods: This study reports a clinical case of a 34-years old man with a pericoronal radiolucent lesion associated to an impacted lower third molar with the presence of radiopaque material inside. The radiological differential diagnosis was calcifying odontogenic tumor, adenomatoid odontogenic tumor and dentigerous cyst...
March 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29706474/a-series-of-240-odontogenic-keratocysts-should-we-continue-to-use-the-terminology-of-keratocystic-odontogenic-tumour-for-the-solid-variant-of-odontogenic-keratocyst
#7
Devrim Kahraman, Omer Gunhan, Bulent Celasun
Most of the odontogenic keratocysts show an indolent behaviour like non-neoplastic lesions. For this reason, the odontogenic keratocyst was reclassified within the odontogenic cysts category in the WHO 2017 classification. Some odontogenic keratocysts may contain satellite cysts or solid squamoid islands within their wall. Recently, a solid form of odontogenic keratocyst has also been described which is composed entirely of multiple epithelial islands and small cysts in a collagenous stroma. The true nature of this variant is unclear yet...
April 11, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29698140/buccal-bifurcation-cyst-two-case-reports-and-a-literature-review
#8
Hee-Ra Kim, Soon-Hyeun Nam, Hyeun-Jung Kim, So-Young Choi
INTRODUCTION: A buccal bifurcation cyst (BBC) is an uncommon inflammatory odontogenic cyst associated with the permanent mandibular first or second molar in children. CASE REPORTS: These reports present two cases of BBC and describes the clinical and radiographic features leading to the diagnosis and the treatment of this lesion. Two patients complained of mandibular buccal swelling around the permanent first molar. The diagnosis of BBC in both cases was based on the clinical and radiographic features...
April 26, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29672163/an-unusual-case-of-an-odontogenic-keratocyst-associated-with-an-ungrafted-alveolar-cleft-a-case-report-and-review-of-the-literature
#9
Sapna Radia, Alexander C Cash, Kanwalraj Moar
We describe an unusual case of an odontogenic keratocyst (OKC) associated with an ungrafted left-sided alveolar cleft in a 10-year-old male patient. There is no previous report in the literature of OKC or other dental cysts associated with an alveolar cleft. We discuss the management of the OKC prior to secondary bone grafting and present this case to highlight the difficulty in the management of OKC concurrent with grafting of the alveolar cleft site, the proximity of unerupted permanent teeth, and possible treatment modalities...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29655415/clinicopathological-analysis-of-232-radicular-cysts-of-the-jawbone-in-a-population-of-southern-taiwanese-patients
#10
Jeng-Huey Chen, Chih-Huang Tseng, Wen-Chen Wang, Ching-Yi Chen, Fu-Hsiung Chuang, Yuk-Kwan Chen
This retrospective study aimed to evaluate the clinicopathological features of 232 cases of radicular cyst (January 2001-December 2016) submitted for histopathological examination to Department of Oral Pathology by endodontists in our institution. Demographic data including age, gender, affected site, involved tooth, and histopathological features, were reviewed. The study population comprised 133 females (57.3%) and 99 males (42.7%), with a mean age of 40.5 years and an age range of 13-78 years. Two-hundred and one cysts occurred in the maxilla (86...
April 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/29652021/an-unusual-presentation-of-ghost-cell-odontogenic-carcinoma-a-case-report-with-review-of-literature
#11
K Remya, S Sudha, Reshmi G Nair, H Jyothi
Ghost cell odontogenic carcinoma (GCOC) is a malignant odontogenic epithelial tumor which is an exceedingly rare, highly aggressive, rapidly growing, and infiltrative tumor forming the malignant counterpart of long-standing benign cystic lesions coming in the spectrum of calcifying odontogenic cysts. To date, only a few cases have been reported in the medical literature. A case of unusual presentation of GCOC is presented and the clinical, histopathological, and immunohistochemical features are discussed along with a literature review...
March 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29620170/increased-level-of-cell-derived-microparticles-in-the-cyst-fluids-of-odontogenic-keratocysts
#12
Qi-Wen Man, Wen-Qun Zhong, Jian-Gang Ren, Jin-Yuan Liu, Yue-Yu Zheng, Rui-Fang Li, B Fidele Nyimi, Gang Chen, Yi-Fang Zhao, Bing Liu
The aim of this study was to examine the level and basic characteristics of cell‑derived microparticles (MPs) in the cyst fluids of odontogenic keratocysts (OKCs). For this purpose, MPs from the cyst fluids (CFMPs) of OKCs were purified by a classic differential centrifugation method and characterized by a transmission electron microscope and fluorescence microscope. Flow cytometric analysis was used to determine the size, concentration and cellular origins of the CFMPs. Moreover, the expression level of receptor activator for nuclear factor‑κB ligand in the OKCs was evaluated by immunohistochemical staining and then analyzed for its correlation with the concentration of CFMPs by Spearman's rank correlation test...
April 5, 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29577431/is-podoplanin-expression-associated-with-tgf-%C3%AE-signaling-in-odontogenic-cysts-and-tumors
#13
Shahroo Etemad-Moghadam, Mojgan Alaeddini
BACKGROUND: Induction of podoplanin by TGF-β has been shown in a number of lesions but not in odontogenic tumors (OTs). We evaluated the association between these markers in OTs for the first time and compared their expression among the different neoplasms. METHODS: Immunohistochemistry using monoclonal antibody against podoplanin and TGF-β was performed on 76 odontogenic cysts and tumors. Spearman's correlation coefficient, Kruskal-Wallis and Mann-Whitney-U tests followed by adjustment with Bonferroni were used for statistical analysis (P<0...
March 26, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29575443/a-lesion-categorized-between-ghost-cell-odontogenic-carcinoma-and-dentinogenic-ghost-cell-tumor-with-ctnnb1-mutation
#14
Yae Ohata, Kou Kayamori, Akane Yukimori, Kanako Sumikura, Toshimitsu Ohsako, Hiroyuki Harada, Kei Sakamoto, Tohru Ikeda
Ghost cell odontogenic carcinoma (GCOC) is a rare malignant neoplasm characterized by the presence of ghost cells. It is considered to arise either de novo or from a preexisting benign precursor, calcifying odontogenic cyst (COC), or dentinogenic ghost cell tumor (DGCT). We report a case of a 44-year-old Japanese male with a left maxillary tumor. The patient received treatment to resect the left maxillary cyst 25 years prior; however, the details were uncertain. The tumor was resected with clear margins. Taken together with the results of histological and immunohistochemical examinations, the tumor was categorized between GCOC and DGCT, and we diagnosed the tumor as GCOC suggesting similarity to DGCT...
March 25, 2018: Pathology International
https://www.readbyqxmd.com/read/29564556/immunohistochemical-evaluation-of-sonic-hedgehog-signaling-pathway-proteins-shh-ptch1-ptch2-smo-gli1-gli2-and-gli3-in-sporadic-and-syndromic-odontogenic-keratocysts
#15
Ana Maria Hoyos Cadavid, E Kaminagakura, M F S D Rodrigues, C A L Pinto, T H N Teshima, F A Alves
AIMS: The aim of this study was to compare the clinical and demographic features of 62 patients presenting sporadic odontogenic keratocysts (OKCs) or OKCs associated with nevoid basal cell carcinoma syndrome (NBCCS). In conjunction with this, we also evaluated the immunohistochemical expression of Shh, Ptch1, Ptch2, Smo, Gli1, Gli2 and Gli3 proteins in 86 OKCs. By doing this, we add to the understanding of the biology of this type of lesion, providing tools that will help facilitate the early diagnosis of NBCCS in those patients where the first manifestation is that of OKCs...
March 21, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29535883/an-extrafollicular-adenomatoid-odontogenic-tumor-mimicking-a-periapical-cyst
#16
Farzaneh Mosavat, Roxana Rashtchian, Negar Zeini, Daryoush Goodarzi Pour, Shabnam Mohammed Charlie, Nazanin Mahdavi
Adenomatoid odontogenic tumor (AOT) is a rare noninvasive odontogenic tumor that occurs mostly in the second decade of life. Based on its tooth association, AOT can be classified into three categories of follicular, extrafollicular, and peripheral types; the follicular classification is considered as the most common type of AOT. This study reported a large extrafollicular case of AOT in a 40-year-old female. She was asymptomatic and tumor was detected accidentally by her dental practitioner. Since the panoramic radiograph showed a well-defined unilocular radiolucent lesion, we observed radiopaque spots within the lesion by using cone beam computed tomography...
2018: Case Reports in Radiology
https://www.readbyqxmd.com/read/29521748/delayed-diagnosis-of-gorlin-goltz-syndrome-the-importance-of-the-multidisciplinary-approach
#17
Jéssica Araújo Figueira, Fábio Roberto de Souza Batista, Karina Rosso, Vanessa Cristina Veltrini, Angelo José Pavan
Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome, is an autosomal dominant inherited disorder with high penetrance and variable expressivity. The classic triad originally described by Gorlin and Goltz in 1960 is composed of multiple nevoid basal cell carcinomas (NBCCs), odontogenic keratocysts (OKCs) in the jaws and bifid ribs. in 1977, this triad was modified by Rayner et al, and to GGS diagnosis, the OKCs had to appear in combination with calcification of the cerebellar falx or palmar and plantar pits...
March 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29513773/guided-bone-regeneration-in-the-treatment-of-a-lateral-periodontal-cyst-2-year-clinical-and-radiologic-follow-up
#18
Stefano Sivolella, Chiara Perin, Marco Capecchi, Valerio Buongiorno, Marialuisa Valente
Lateral periodontal cysts (LPCs) are rare odontogenic cysts of developmental origin. A 52-year-old man presented with an asymptomatic gingival swelling located between the mandibular left canine and first premolar, both of which were vital. Radiography showed a well-circumscribed radiolucent area and loss of the lamina dura around the tooth socket in contact with the lesion and of the interproximal buccal bone. The lesion was enucleated. The defect was immediately grafted with a 1:1 mixed autologous and heterologous bone graft covered with a collagen membrane...
March 7, 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29508125/investigation-of-clinicopathological-parameters-and-expression-of-cox-2-bcl-2-pcna-and-p53-in-primary-and-recurrent-sporadic-odontogenic-keratocysts
#19
Tomasz Kaczmarzyk, Konrad Kisielowski, Rafał Koszowski, Magdalena Rynkiewicz, Ewa Gawełek, Karolina Babiuch, Anna Bednarczyk, Bogna Drozdzowska
OBJECTIVES: Odontogenic keratocyst (OKC) presents considerable variation in aggressiveness and propensity for recurrence, yet hitherto, no explicit clinicopathological features have been determined to clearly demonstrate the potential for relapse. This retrospective study aims to investigate the prognostic relevance of various clinicopathological features as well as immunoexpression of COX-2, bcl-2, PCNA, and p53 in sporadic OKC. MATERIALS AND METHODS: Among 41 patients with OKC treated by enucleation, the frequency of recurrence for various clinicopathological features as well as immunoexpression for COX-2, bcl-2, PCNA, and p53 was evaluated...
March 5, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29491624/trigeminal-neuralgia-induced-by-odontogenic-keratocyst-associated-with-impacted-supernumerary-teeth-a-rare-case-report
#20
Annaji Araleri Gopalkrishna, B N Tejasree, M Manjunath, D P Ashwin
Odontogenic keratocyst(OKC)is a cyst oftooth origin with an aggressive behavior including a high recurrence rate, it has been rechristened to keratocystic odontogenic tumor(KCOT) as it be the reflects its neoplastic nature. We report a case of KCOT in association with an impacted supernumerary tooth along with Trigeminal Neuralgia, that subsided by itself after removal of the cyst.
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
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