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https://www.readbyqxmd.com/read/29042524/-autoimmune-and-epilepsy
#1
Riki Matsumoto, Mitsuhiro Sakamoto, Akio Ikeda
The recent discovery of autoimmune antibodies to the neuronal cell surface membrane and extra- or intra-cellular proteins, such as NMDAR and LGI1, shed light on a proposed new etiology of epilepsy, namely, "autoimmune epilepsy". A large part of this entity most likely belongs to a forme fruste of autoimmune (limbic) encephalitis. Seizures are usually subacute in onset and refractory to antiepileptic medications. Patients occasionally manifest multiple seizure semiologies, such as autonomic or faciobrachial dystonic seizures...
October 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29039074/the-usefulness-of-stereo-electroencephalography-seeg-in-the-surgical-management-of-focal-epilepsy-associated-with-hidden-temporal-pole-encephalocele-a-case-report-and-literature-review
#2
João Paulo Sant Ana Santos de Souza, Jeff Mullin, Connor Wathen, Juan Bulacio, Patrick Chauvel, Lara Jehi, Jorge Gonzalez-Martinez
The authors report a case of 18-year-old woman with partial complex seizures compatible with temporal epilepsy by semiology. Due to medical refractoriness, she was referred to pre-surgical evaluation. Initially, MRI showed no significant structural abnormality and superficial scalp EEG demonstrated epileptiform activity in the frontotemporal areas. Due to the lack of clear MRI abnormalities and the potential involvement of dominant mesial temporal structures by seizure semiology and non-invasive data, extra-operative invasive evaluation using stereo-electroencephalography (SEEG) methodology was indicated...
October 16, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/29037338/-the-many-faces-of-orbitofrontal-syndrome
#3
Jose Fernando Muñoz Zúñiga
Orbitofrontal syndrome is a neuropsychiatric syndrome composed of cognitive, affective and behavioural symptoms, disrupting some of the traits that define us as a species, like cognitive flexibility and affective regulation. In order to effectively treat the condition, the clinician needs to be familiar with both the functional neuroanatomy and the neuropsychiatric semiology of the syndrome. A review of the literature is presented, emphasising the broad spectrum of clinical manifestations of the syndrome, together with three clinical vignettes showing the many faces of the syndrome...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29031194/the-prevalence-and-characteristics-of-epilepsy-in-patients-with-multiple-sclerosis-in-nordland-county-norway
#4
Espen Benjaminsen, Kjell-Morten Myhr, Karl B Alstadhaug
PURPOSE: The prevalence of epilepsy among patients with multiple sclerosis (MS) has been found higher than in the general population. Although cortical pathology may be involved, the causal link between MS and epileptic seizures is still unclear. We aimed to identify and describe the patients with active epilepsy in a previously described population based MS-cohort. METHODS: Medical records of all patients with MS in Nordland County on January 1, 2010, were scrutinizing for evidence of comorbid seizures and epilepsy...
October 6, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28990168/automated-analysis-of-seizure-semiology-and-brain-electrical-activity-in-presurgery-evaluation-of-epilepsy-a-focused-survey
#5
REVIEW
David Ahmedt-Aristizabal, Clinton Fookes, Sasha Dionisio, Kien Nguyen, João Paulo S Cunha, Sridha Sridharan
Epilepsy being one of the most prevalent neurological disorders, affecting approximately 50 million people worldwide, and with almost 30-40% of patients experiencing partial epilepsy being nonresponsive to medication, epilepsy surgery is widely accepted as an effective therapeutic option. Presurgical evaluation has advanced significantly using noninvasive techniques based on video monitoring, neuroimaging, and electrophysiological and neuropsychological tests; however, certain clinical settings call for invasive intracranial recordings such as stereoelectroencephalography (SEEG), aiming to accurately map the eloquent brain networks involved during a seizure...
October 9, 2017: Epilepsia
https://www.readbyqxmd.com/read/28967460/ictal-symmetric-tonic-extension-posturing-and-postictal-generalized-eeg-suppression-arising-from-sleep-in-children-with-epilepsy
#6
Kazuo Okanari, Hiroshi Otsubo, Elizabeth Kouzmitcheva, Jagadish Rangrej, Shiro Baba, Ayako Ochi, Tohru Okanishi, Yoichiro Homma, Dragos A Nita, Elizabeth J Donner
BACKGROUND: The identification of a biomarker for sudden unexpected death in epilepsy (SUDEP) has the potential to save lives. Generalized convulsive seizures and postictal generalized suppression on electroencephalography (EEG) most often precede sudden unexpected death in epilepsy (SUDEP) and are potential biomarkers. We identify the EEG and seizure characteristics associated with postictal generalized EEG suppression in children with epilepsy. METHODS: Video EEGs were reviewed for seizure type, duration and semiology, and electrographic features...
July 4, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28934527/proton-mr-spectroscopy-in-patients-with-sleep-related-hypermotor-epilepsy-she-evidence-of-altered-cingulate-cortex-metabolism
#7
Ilaria Naldi, Francesca Bisulli, Claudia Testa, Giovanni Rizzo, Lorenzo Ferri, Laura L Gramegna, Laura Licchetta, Raffaele Lodi, Caterina Tonon, Paolo Tinuper
Study Objectives: To identify structural and/or metabolic alterations in patients with sleep-related hypermotor epilepsy (SHE) using magnetic resonance imaging (MRI) and proton MR spectroscopy (1H-MRS). Methods: Nineteen SHE patients (seven males; 34.7 ± 9.7 years, mean age ± standard deviation) and 17 matched healthy volunteers (seven males; 34.0 ± 8.9 years) were included in the study. In all patients, the diagnosis of SHE was confirmed by video-polysomnographic recording of seizures...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28928072/orbitofrontal-epilepsy-case-series-and-review-of-literature
#8
Imane Samah Chibane, Olivier Boucher, François Dubeau, Thi Phuoc Yen Tran, Ismail Mohamed, Richard McLachlan, R Mark Sadler, Richard Desbiens, Lionel Carmant, Dang Khoa Nguyen
BACKGROUND: Orbitofrontal epilepsy (OFE) is less known and is poorly characterized in comparison with temporal lobe epilepsy, partly because it is rare and possibly because it is unrecognized and therefore underestimated. OBJECTIVE: This paper aimed to better characterize seizure semiology, presurgical findings, and surgical outcomes in patients with OFE. METHODS: We retrospectively reviewed all confidently established OFE cases from six Canadian epilepsy monitoring units between 1988 and 2014, and in the literature between 1972 and 2017...
September 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28927709/high-spirituality-may-be-associated-with-right-hemispheric-lateralization-in-korean-adults-living-with-epilepsy
#9
Sang-Ahm Lee, Myung-Ah Ko, Eun-Ju Choi, Ji-Ye Jeon, Han Uk Ryu
PURPOSE: Although it is known that epilepsy and spirituality are related, spirituality in epilepsy has received relatively little clinical and scientific attention. Therefore, we investigated which epilepsy-related factors are associated with high spirituality in Korean adults living with epilepsy. METHODS: This cross-sectional study was conducted in two university hospitals in Korea. Spirituality was assessed using the 6-item Spirituality Self-Rating Scale (SSRS)...
September 15, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28926747/ictal-source-imaging-and-electroclinical-correlation-in-self-limited-epilepsy-with-centrotemporal-spikes
#10
Jørgen Alving, Martin Fabricius, Ivana Rosenzweig, Sándor Beniczky
PURPOSE: To elucidate the localization of ictal EEG activity, and correlate it to semiological features in self-limited epilepsy with centrotemporal spikes (formerly called "benign epilepsy with centrotemporal spikes"). METHODS: We have performed ictal electric source imaging, and we analysed electroclinical correlations in three patients with self-limited epilepsy with centrotemporal spikes. RESULTS: The source of the evolving rhythmic ictal activity (9...
September 14, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28924357/developmental-dysplasia-of-the-hip-do-the-responsible-for-screening-know-what-to-do
#11
Bruno Gonçalves Schröder E Souza, Tiago Evangelista de Melo, Thiago Mattos Resende, Rafaela Clara Resende da Silva, Soraya Amanda Cruz, Valdeci Manoel de Oliveira
OBJECTIVE: To evaluate the knowledge on developmental dysplasia of the hip (DDH) by professionals involved in its diagnosis. METHODS: This is a cross-sectional study using questionnaires to assess the knowledge about DDH. Orthopedic surgeons and pediatricians, residents and medical students from a tertiary teaching hospital were included in the study. RESULTS: We evaluated 142 medical students, eight orthopedic residents, ten pediatric residents, seven pediatricians, and nine orthopedic surgeons; 50% declared not having examined any DDH case in the last year and only three had diagnosed more than 10 cases during their career...
November 2016: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28921161/deep-brain-stimulation-for-refractory-temporal-lobe-epilepsy-a-systematic-review-and-meta-analysis-with-an-emphasis-on-alleviation-of-seizure-frequency-outcome
#12
Bowen Chang, Jiwen Xu
OBJECTIVE: Conflicting conclusions have been reported regarding predictors of deep brain stimulation (DBS) outcome in patients with refractory temporal lobe epilepsy (TLE). The main goal of this meta-analysis study was to identify possible predictors of remarkable seizure reduction (RSR). METHODS: We conducted a comprehensive search of English-language literature published since 1990 and indexed in PubMed, Embase, and the Cochrane Library that addressed seizure outcomes in patients who underwent DBS for refractory TLE...
September 18, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28913167/ictal-conduction-aphasia-and-ictal-angular-gyrus-syndrome-as-rare-manifestations-of-epilepsy-the-importance-of-ictal-testing-during-video-eeg-monitoring
#13
Johann Philipp Zöllner, Anja Haag, Anke Hermsen, Sebastian Bauer, Friederike Stahl, Karina Wulf, Katja Menzler, Philipp S Reif, Marlies Wagner, Axel Pagenstecher, Ulrich Sure, Susanne Knake, Felix Rosenow, Adam Strzelczyk
The aim of these two case reports is to demonstrate that a predefined, structured, multimodal clinical bed-side testing during seizures in a long-term video-EEG monitoring setting facilitates diagnosis of complex neuropsychological syndromes. To the best of our knowledge, we present the first case of conduction aphasia as the sole ictal semiology, and a patient with focal seizures producing an angular gyrus syndrome in the speech dominant hemisphere. The relevance of diagnosing ictal aphasic and angular gyrus syndromes and localizing the symptomatogenic zone is discussed...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28899823/a-predictive-radiological-analysis-of-short-stems-versus-both-shortened-and-long-stems-in-primary-hip-replacement-a-case-control-study-of-100-cases-of-metha-versus-abg-ii-and-omnifit-ha-at-2-8years-follow-up
#14
J-A Epinette, M Brax, Y Chammaï
INTRODUCTION: Short hip stems, intended to conserve bone stock and ensure a more physiological distribution of stress in the femur under loading, are meeting with renewed interest. Radiologic semiology is not known exactly, particularly in relation to conventional implants; we therefore conducted a case-control study of 3 types of implant differing only in stem length: short, shortened or long. The aim was: (1) to compare radiographic aspects, (2) to attempt to systematize medium-term radiologic status for the 3 types, and (3) to assess the impact of radiographic aspect on loosening and revision rates...
September 9, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28883420/personalized-structural-image-analysis-in-patients-with-temporal-lobe-epilepsy
#15
Christian Rummel, Nedelina Slavova, Andrea Seiler, Eugenio Abela, Martinus Hauf, Yuliya Burren, Christian Weisstanner, Serge Vulliemoz, Margitta Seeck, Kaspar Schindler, Roland Wiest
Volumetric and morphometric studies have demonstrated structural abnormalities related to chronic epilepsies on a cohort- and population-based level. On a single-patient level, specific patterns of atrophy or cortical reorganization may be widespread and heterogeneous but represent potential targets for further personalized image analysis and surgical therapy. The goal of this study was to compare morphometric data analysis in 37 patients with temporal lobe epilepsies with expert-based image analysis, pre-informed by seizure semiology and ictal scalp EEG...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28882721/clinical-presentation-of-neurocysticercosis-related-epilepsy
#16
REVIEW
Kevin R Duque, Jorge G Burneo
Neurocysticercosis (NCC) is the most common parasitic infection of the central nervous system and a major risk factor for seizures and epilepsy. Seizure types in NCC vary largely across studies and seizure semiology is poorly understood. We discuss here the studies regarding seizure types and seizure semiology in NCC, and examine the clinical presentation in patients with NCC and drug-resistant epilepsy. We also provide evidence of the role of MRI and EEG in the diagnosis of NCC-related epilepsy. Focal seizures are reported in 60-90% of patients with NCC-related epilepsy, and around 90% of all seizures registered prospectively are focal not evolving to bilateral tonic-clonic seizures...
September 4, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28876177/ancient-indian-concepts-about-phenomenology-biology-and-therapeutics-of-epilepsy
#17
Ravindra Arya
This article discusses etiology, pathogenesis, symptoms, and treatment of epilepsy, as described in Charaka Samhitā (translation: Charaka's Compendium) and Sushruta Samhitā, the two core texts of Ayurveda, an ancient system of medicine. Ayurveda emphasized amnesia and loss of consciousness as core features of epileptic seizures (Sanskrit: apasmar; translation: apa negation, smaran memory) and recognized that seizures occur due to a disturbance in brain function or flow of "humors" to the brain. Semiology of various seizure types was well described...
September 6, 2017: Journal of the History of the Neurosciences
https://www.readbyqxmd.com/read/28871346/-differential-diagnosis-of-dissociative-seizures
#18
REVIEW
A Joos, K Baumann, C E Scheidt, C Lahmann, R König, H-J Busch, A Schulze-Bonhage
Patient history taking and semiology provide seminal clues to the diagnosis of dissociative seizures. Openness and alertness of the treating physician are essential. Video-electroencephalogram(EEG)-based analyses of the events are crucial to establish the correct diagnosis, particularly in complex cases. The patient-doctor relationship is of particular importance in order to successfully motivate the patient for psychotherapeutic treatment. Coexisting psychiatric morbidity as well as other functional somatic symptoms must be actively explored...
September 4, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28865883/semiology-of-psychogenic-nonepileptic-seizures-an-international-cross-cultural-study
#19
Ali A Asadi-Pooya, Kette Valente, Ruda Alessi, Jennifer Tinker
PURPOSE: We compared the semiology of psychogenic nonepileptic seizures (PNES) between patients from the USA and Brazil. This international cross-cultural comparative study may expand understanding of PNES across the borders. METHODS: We retrospectively investigated all patients with PNES admitted to one epilepsy center in the USA and one in Brazil. We classified their seizures into four classes: generalized motor, akinetic, focal motor, and subjective symptoms...
August 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28843069/new-onset-status-epilepticus-in-older-patients-clinical-characteristics-and-outcome
#20
M P Malter, R D Nass, T Kaluschke, G R Fink, L Burghaus, C Dohmen
PURPOSE: We here evaluated (1) the differential characteristics of status epilepticus (SE) in older (≥60 years) compared to younger adults (18-59 years). In particular, we were interested in (2) the proportion and characteristics of new onset SE in patients with no history of epilepsy (NOSE) in older compared to younger adults, and (3) predictive parameters for clinical outcome in older subjects with NOSE. METHODS: We performed a monocentric retrospective analysis of all adult patients (≥18years) admitted with SE to our tertiary care centre over a period of 10 years (2006-2015) to evaluate clinical characteristics and short-time outcome at discharge...
October 2017: Seizure: the Journal of the British Epilepsy Association
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