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https://www.readbyqxmd.com/read/28543030/defining-epileptogenic-networks-contribution-of-seeg-and-signal-analysis
#1
REVIEW
Fabrice Bartolomei, Stanislas Lagarde, Fabrice Wendling, Aileen McGonigal, Viktor Jirsa, Maxime Guye, Christian Bénar
Epileptogenic networks are defined by the brain regions involved in the production and propagation of epileptic activities. In this review we describe the historical, methodologic, and conceptual bases of this model in the analysis of electrophysiologic intracerebral recordings. In the context of epilepsy surgery, the determination of cerebral regions producing seizures (i.e., the "epileptogenic zone") is a crucial objective. In contrast with a traditional focal vision of focal drug-resistant epilepsies, the concept of epileptogenic networks has been progressively introduced as a model better able to describe the complexity of seizure dynamics and realistically describe the distribution of epileptogenic anomalies in the brain...
May 20, 2017: Epilepsia
https://www.readbyqxmd.com/read/28527977/the-association-of-arachnoid-cysts-and-focal-epilepsy-hospital-based-case-control-study
#2
Ivan Nikolić, Aleksandar Ristić, Nikola Vojvodić, Vladimir Baščarević, Andrej Ilanković, Ivana Berisavac, Tijana Đukić, Dragoslav Sokić
OBJECTIVE: Arachnoid cysts (ACs) are common findings in brain MRI. Our aim was to examine frequency and distribution of ACs in patients with focal epilepsy, compared to healthy control subjects, and to investigate the association of AC and electro-clinical features of focal epilepsy. PATIENTS AND METHODS: We performed a retrospective case-control study, using data from 180 patients that underwent video-EEG monitoring between 2009 and 2012, and of 114 healthy controlled subjects...
May 12, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28524221/-epileptic-spasms-in-infants-beyond-hypsarrhythmia
#3
M Garcia-Fernandez
Epileptic spasms are the most frequent type of epileptic seizures in infants. They can also occur beyond the period of infancy, within the context of other epileptic encephalopathies or as an expression of a focal or generalised epilepsy. The clinical semiology of epileptic spasms varies greatly. They sometimes consist of very subtle clinical manifestations, which occur in series, without the typical axorhizomelic contraction, or in association with focal seizures. The critical EEG correlate is also very variable and basically consists of the combination of a hypervoltage slow wave, a bout of rapid low-amplitude activity or a diffuse attenuation of the trace...
May 17, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28520633/insular-cortex-surgery-for-the-treatment-of-refractory-epilepsy
#4
Marec von Lehe, Yaroslav Parpaley
Focal epilepsy originating from the insular cortex is rare. One reason is the small amount of cortical tissue compared with other lobes of the brain. However, the incidence of insular epilepsy might be underestimated because of diagnostic difficulties. The semiology and the surface EEG are often not meaningful or even misleading, and elaborated imaging might be necessary. The close connections of the insular cortex with other potentially epileptogenic areas, such as the temporal lobe or frontal/central cortex, is increasingly recognized as possible reason for failure of epilepsy surgery for temporal or extratemporal seizures...
May 16, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28511919/the-debate-treatment-after-the-first-seizure-the-pro
#5
REVIEW
David G Olmes, Hajo M Hamer
According to current diagnosis criteria, first seizures constitute beginning epilepsy when they carry recurrence risks of ≥60% over the next 10 years. This is frequently the case and warrants AED treatment. Evidence argues against deferring treatment when provoking factors such as sleep deprivation are reported. There are several characteristics of first seizures which markedly increase recurrence risk but not clearly beyond 60%. This includes status epilepticus or seizure flurries at first manifestation or focal semiology indicating focal epilepsy...
May 4, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28501143/do-we-know-how-to-diagnose-epilepsy-early-in-alzheimer-s-disease
#6
REVIEW
B Cretin, N Philippi, O Bousiges, L Dibitonto, F Sellal, C Martin-Hunyadi, F Blanc
Epilepsy is an increasingly recognized comorbidity in Alzheimer's disease (AD). First described as generalized in dementia patients, epileptic AD patients are nowadays fully described in earlier stages of the disease (with mild or subjective cognitive impairment). At such early stages, patients may present not only with generalized seizures, but also with focal seizures (commonly localized in the frontal or temporal lobe). Thus, partial or generalized epilepsy is part of the semiological spectrum of AD that should be borne in mind at all stages of disease to ensure early identification and prevent the risk of repeated seizures (such as accidents, injury, progression of cognitive impairment)...
May 10, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28495218/effects-of-hippocampal-low-frequency-stimulation-in-idiopathic-non-human-primate-epilepsy-assessed-via-a-remote-sensing-enabled-neurostimulator
#7
Thomas A Wozny, Witold J Lipski, Ahmad Alhourani, Efstathios D Kondylis, Arun Antony, R Mark Richardson
Individuals with pharmacoresistant epilepsy remain a large and under-treated patient population. Continued technologic advancements in implantable neurostimulators have spurred considerable research efforts directed towards the development of novel antiepileptic stimulation therapies. However, the lack of adequate preclinical experimental platforms has precluded a detailed understanding of the differential effects of stimulation parameters on neuronal activity within seizure networks. In order to chronically monitor seizures and the effects of stimulation in a freely-behaving non-human primate with idiopathic epilepsy, we employed a novel simultaneous video-intracranial EEG recording platform using a state-of-the-art sensing-enabled, rechargeable clinical neurostimulator with real-time seizure detection and wireless data streaming capabilities...
May 7, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28479797/lennox-gastaut-syndrome-a-prospective-follow-up-study
#8
Bhanu Pratap Rathaur, Ravindra Kumar Garg, Hardeep Singh Malhotra, Neeraj Kumar, Praveen Kumar Sharma, Rajesh Verma, Ravi Uniyal
OBJECTIVES: Lennox-Gastaut syndrome is a catastrophic epileptic encephalopathy. In Lennox-Gastaut syndrome, seizures are resistant to pharmacological treatment. In this prospective study, we evaluated the clinical features, neuroimaging, and response to treatment. MATERIALS AND METHODS: Forty-three consecutive newly diagnosed patients of Lennox-Gastaut syndrome were enrolled in the study. Baseline clinical assessment included seizure semiology, seizure frequency, electroencephalography, and neuroimaging...
April 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28434238/the-characteristics-and-long-term-course-of-epilepsy-in-lipoid-proteinosis-a-spectrum-from-mild-to-severe-seizures-in-relation-to-ecm1-mutations
#9
Emel Oguz Akarsu, Firdevs Dinçsoy Bir, Can Baykal, Volkan Taşdemir, Bülent Kara, Nerses Bebek, Candan Gürses, Oya Uyguner, Betül Baykan
Lipoid proteinosis (LP) is a rare autosomal recessive disease characterized by deposition of hyaline material in skin and mucosae. Epilepsy, as an extracutaneous manifestation associated with typical mesial temporal calcifications, has already been identified, but its characteristics and long-term prognosis have not been thoroughly investigated. We included 7 consecutive patients with LP with typical intracranial calcifications out of 16 patients with ECM1 mutations and investigated the semiologic features, ictal and interictal EEG findings, and long-term prognosis of epilepsy in this genodermatosis...
April 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/28427022/stereotypy-of-psychogenic-nonepileptic-seizures
#10
Moshe Herskovitz
Psychogenic nonepileptic seizures (PNES) are defined as paroxysmal episodes in which epileptic semiology features are manifested, without the characteristic concomitant electrical discharges seen in epileptic seizures. Although many studies have dealt with semiologic classification of PNES, most of the studies did not raise the question of consistency of PNES in the same patient. The aim of this study was to measure the degree of consistency of PNES among individual patients. We retrospectively reviewed medical records and video- EEG records of all adult patients who underwent monitoring in our center from August 1st 2013 to May 31st 2015...
May 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28425885/an-objective-structured-clinical-exam-to-assess-semiology-skills-of-medical-students
#11
Vitor Hugo Pereira, Pedro Morgado, Mónica Gonçalves, Liliana Costa, Nuno Sousa, João José Cerqueira
INTRODUCTION: Mastery of history taking and physical exam skills is a key competence of medical students. Objective Structured Clinical Examinations are the gold standard to assess these competencies, but their implementation in Portugal is poorly documented. We describe the implementation and our seven years experience with a high-stakes Objective Structured Clinical Examination to assess these skills in the School of Medicine, University of Minho. MATERIAL AND METHODS: Our Objective Structured Clinical Examination is in place since 2010 and has been subject to continuous improvements, including the adoption of a standard setting procedure and an increase in the number of stations...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28416780/new-onset-epilepsy-in-the-elderly-clinical-radiological-and-electroencephalographic-features-and-treatment-responses
#12
Erum M Shariff, Fahd A AlKhamis
OBJECTIVE: To evaluate new onset epilepsy characteristics, etiology, radiological and electroencephalographic features and to document treatment response in the elderly. METHODS: This was a retrospective study carried out in King Fahd Medical City, Riyadh, Kingdom of Saudi Arabia, from 2010 to 2013. Medical records were searched to recruit patients. Hundred and nineteen patients were enrolled who fulfill the inclusion criteria. Clinical data with respect to seizure semiology, etiology, electroencephalographic findings, radiological findings, co-morbidities, and anti-epileptic drug (AED) therapy were assessed...
April 2017: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/28403292/semiotics-and-semiology-of-nursing-evaluation-of-undergraduate-students-knowledge-on-procedures
#13
Gabriela de Sousa Martins Melo, Manuela Pinto Tibúrcio, Camylla Cavalcante Soares de Freitas, Quinídia Lúcia Duarte de Almeida Quithé de Vasconcelos, Isabel Karolyne Fernandes Costa, Gilson de Vasconcelos Torres
OBJECTIVE: to assess the knowledge of scholars on Nursing regarding simple hands hygiene (SHH), blood pressure measurement (BP), peripheral venipuncture (PV) with venous catheter and male urethral catheterization delay (UCD) procedures. METHOD: quantitative study carried out between February and May 2014, with 186 undergraduate Nursing students from 5th to 9th period of a public university of Rio Grande do Norte, with application of four questionnaires. One carried out descriptive and analytic analysis...
April 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28397999/scalp-eeg-ictal-gamma-and-beta-activity-during-infantile-spasms-evidence-of-focality
#14
Hiroki Nariai, Jules Beal, Aristea S Galanopoulou, Wenzhu B Mowrey, Stephan Bickel, Yoshimi Sogawa, Rana Jehle, Shlomo Shinnar, Solomon L Moshé
OBJECTIVE: We investigated temporal and spatial characteristics of ictal gamma and beta activity on scalp EEG during spasms in patients with West syndrome (WS) to evaluate potential focal cortical onset. METHODS: A total of 1,033 spasms from 34 patients with WS of various etiologies were analyzed on video-electroencephalography (EEG) using time-frequency analysis. Ictal gamma (35-90 Hz) and beta (15-30 Hz) activities were correlated with visual symmetry of spasms, objective EMG (electromyography) analysis, and etiology of WS...
May 2017: Epilepsia
https://www.readbyqxmd.com/read/28393996/-interactive-tools-to-standardize-semiology-teaching
#15
Alejandro González, Bryan Vargas, Vicente González, Ignacio Reyes, Alberto Sarfatis
BACKGROUND: The learning process for medical semiology depends on multidisciplinary teaching activities, including simulation tools. These tools should achieve a standardization level aiming at a same level of basic knowledge in each student. AIM: To evaluate an interactive online semiology learning tool. MATERIAL AND METHODS: An interactive online learning method for medical semiology was developed. It focused mainly on physical examination and incorporated audiovisual and self-explanatory elements, to strengthen the acquisition of skills and basic knowledge for each standardized clinical learning simulation session...
December 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28393015/epileptic-angina
#16
Sachin Sureshbabu, Dinesh Nayak, Sudhir Peter, Chindripu Sobhana, Gaurav Mittal
PURPOSE: To investigate the probable ictal origin of unexplained episodic chest pain and if possible to lateralize and localize the epileptic focus. METHODS: A 14 year old boy presented with episodic short lasting localized chest pain. His cardiac and other systemic work-up were normal. MRI brain did not reveal any structural pathology. Video telemetry was done for characterization of the paroxysms. RESULTS: Interictal record showed left fronto-central epileptiform discharges...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28389021/ictal-speech-and-language-dysfunction-in-adult-epilepsy-clinical-study-of-95%C3%A2-seizures
#17
C Dussaule, C Cauquil, C Flamand-Roze, J-P Gagnepain, V Bouilleret, C Denier, P Masnou
PURPOSE: To analyze the semiological characteristics of the language and speech disorders arising during epileptic seizures, and to describe the patterns of language and speech disorders that can predict laterality of the epileptic focus. METHOD: This study retrospectively analyzed 95 consecutive videos of seizures with language and/or speech disorders in 44 patients admitted for diagnostic video-EEG monitoring. Laterality of the epileptic focus was defined according to electro-clinical correlation studies and structural and functional neuroimaging findings...
April 4, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28384518/semiology-of-subtle-motor-phenomena-in-critically-ill-patients
#18
Bogdan Florea, Simona Alexandra Beniczky, Helga Demény, Sándor Beniczky
PURPOSE: to investigate the semiology of subtle motor phenomena in critically ill patients, with- versus without nonconvulsive status epilepticus (NCSE). METHODS: 60 consecutive comatose patients, in whom subtle motor phenomena were observed in the intensive care unit (ICU), were analysed prospectively. The semiology of the subtle phenomena was described from video-recordings, blinded to all other data. For each patient, the type, location and occurrence-pattern/duration were described...
March 30, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28378422/derivation-and-initial-validation-of-a-surgical-grading-scale-for-the-preliminary-evaluation-of-adult-patients-with-drug-resistant-focal-epilepsy
#19
Patricia Dugan, Chad Carlson, Nathalie Jetté, Samuel Wiebe, Marjorie Bunch, Ruben Kuzniecky, Jacqueline French
OBJECTIVE: Presently, there is no simple method at initial presentation for identifying a patient's likelihood of progressing to surgery and a favorable outcome. The Epilepsy Surgery Grading Scale (ESGS) is a three-tier empirically derived mathematical scale with five categories: magnetic resonance imaging (MRI), electroencephalography (EEG), concordance (between MRI and EEG), semiology, and IQ designed to stratify patients with drug-resistant focal epilepsy based on their likelihood of proceeding to resective epilepsy surgery and achieving seizure freedom...
April 4, 2017: Epilepsia
https://www.readbyqxmd.com/read/28319879/how-can-we-explain-the-frontal-presentation-of-insular-lobe-epilepsy-the-impact-of-non-linear-analysis-of-insular-seizures
#20
Koichi Hagiwara, Julien Jung, Romain Bouet, Chifaou Abdallah, Marc Guénot, Luis Garcia-Larrea, François Mauguière, Sylvain Rheims, Jean Isnard
OBJECTIVE: For a decade it has been known that the insular lobe epilepsy can mimic frontal lobe epilepsy. We aimed to clarify the pattern of functional coupling occurring during the frontal presentation. METHODS: We analyzed five insular lobe epilepsy patients. Frontal semiology was predominant for three of them, whereas insular semiology was predominant for the two others. We applied the non-linear regression analysis to stereoelectroencephalography-recorded seizures...
May 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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