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https://www.readbyqxmd.com/read/28644201/insular-epilepsy-semiology-and-noninvasive-investigations
#1
Sami Obaid, Younes Zerouali, Dang Khoa Nguyen
In this review, authors discuss the semiology and noninvasive investigations of insular epilepsy, an underrecognized type of epilepsy, which may mimic other focal epilepsies. In line with the various functions of the insula and its widespread network of connections, insular epilepsy may feature a variety of early ictal manifestations from somatosensory, visceral, olfactory, gustatory, or vestibular manifestations. Depending on propagation pathways, insular seizures may also include altered consciousness, dystonic posturing, complex motor behaviors, and even autonomic features...
July 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28644200/electrical-stimulations-of-the-human-insula-their-contribution-to-the-ictal-semiology-of-insular-seizures
#2
Laure Mazzola, François Mauguière, Jean Isnard
INTRODUCTION: Stereotactic stimulations of the insular cortex through intracranial electrodes aim at characterizing the semiology of insular seizures. These stimulations, carried out in the context of Stereo-Electro-Encephalography (SEEG) during presurgical monitoring of epilepsy, reproduce the ictal symptoms observed during the development of insular seizures. METHODS: The authors reviewed the results of insular stimulations performed in 222 patients admitted between 1997 and 2015 for presurgical SEEG exploration of atypical temporal or perisylvian epilepsy...
July 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28643843/perisylvian-including-insular-childhood-epilepsy-presurgical-workup-and-surgical-outcome
#3
Elena Freri, Sara Matricardi, Francesca Gozzo, Massimo Cossu, Tiziana Granata, Laura Tassi
OBJECTIVE: To report the presurgical workup, surgical procedures, and outcomes in a series of pediatric patients with drug-resistant epilepsy involving the perisylvian/insular regions. METHODS: We retrospectively assessed 16 pediatric patients affected by drug-resistant focal epilepsy involving perisylvian/insular regions, who consecutively underwent tailored resective surgery. All patients underwent a detailed presurgical workup, which included the analysis of the anatomoelectroclinical correlations with scalp electroencephalography (EEG) and/or with stereo-electroencephalography (SEEG), brain magnetic resonance imaging (MRI), and comprehensive cognitive and neuropsychological evaluations...
June 23, 2017: Epilepsia
https://www.readbyqxmd.com/read/28637943/stereoelectroencephalography-indication-and-efficacy
#4
Koji Iida, Hiroshi Otsubo
Stereoelectroencephalography (SEEG) is a method for invasive study of patients with refractory epilepsy. Localization of the epileptogenic zone in SEEG relied on the hypothesis of anatomo-electro-clinical analysis limited by X-ray, analog electroencephalography (EEG), and seizure semiology in the 1950s. Modern neuroimaging studies and digital video-EEG have developed the hypothesis aiming at more precise localization of the epileptic network. Certain clinical scenarios favor SEEG over subdural EEG (SDEEG). SEEG can cover extensive areas of bilateral hemispheres with highly accurate sampling from sulcal areas and deep brain structures...
June 20, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28637636/epilepsy-after-cerebral-infection-review-of-the-literature-and-the-potential-for-surgery
#5
Georgia Ramantani, Hans Holthausen
The risk of unprovoked seizures in population-based cohorts of cerebral infection survivors is 7-8% in developed countries, rising to considerably higher rates in resource-poor countries. The main risk factors for epilepsy after cerebral infection, besides acute seizures, are infection-associated brain lesions and status epilepticus during the acute phase. Despite the high prevalence of pharmacoresistant epilepsies after cerebral infections, especially in patients with MRI-identifiable lesions, only a small minority undergoes epilepsy surgery...
June 19, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28628290/-pain-complaints-in-a-patient-with-schizophrenia
#6
I Caubo, C Piette, R Fontaine, G Scantamburlo
Schizophrenia is a complex pathology. Its prevalence reaches almost 1 %. Its semiology can be diversified. Sensorial perception can be altered included pain perception. Most of the studies conclude that psychotic patients have a hypoalgesia. It's important to consider this fact to avoid missing potentially grave somatic disease.
June 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28625947/intracranial-investigation-of-a-patient-with-nodular-heterotopia-and-hippocampal-sclerosis-dealing-with-a-dual-pathology
#7
Lady Diana Ladino, Chelsea Dash, Adam Wu, Jose Francisco Tellez-Zenteno
The pre-operative assessment and surgical management of patients with dual pathology is challenging. We describe a patient with drug-resistant focal epilepsy with hippocampal sclerosis and extensive periventricular nodular heterotopia in the same hemisphere. The semiology, scalp EEG, and imaging were divergent, but the presence of focal interictal and ictal epileptic discharges of the putative ictal onset zone resulted in successful localization of the epileptogenic zone. A less aggressive resection was performed based on intracranial EEG recording...
June 12, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28622546/the-semiology-of-febrile-seizures-focal-features-are-frequent
#8
Michihiko Takasu, Tetsuo Kubota, Takeshi Tsuji, Hirokazu Kurahashi, Shingo Numoto, Kazuyoshi Watanabe, Akihisa Okumura
OBJECTIVE: To clarify the semiology of febrile seizures (FS) and to determine the frequency of FS with symptoms suggestive of focal onset. METHODS: FS symptoms in children were reported within 24h of seizure onset by the parents using a structured questionnaire consisting principally of closed-ended questions. We focused on events at seizure commencement, including changes in behavior and facial expression, and ocular and oral symptoms. We also investigated the autonomic and motor symptoms developing during seizures...
June 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28621621/indications-technique-and-safety-profile-of-insular-stereoelectroencephalography-electrode-implantation-in-medically-intractable-epilepsy
#9
Soha Alomar, Jeffrey P Mullin, Saksith Smithason, Jorge Gonzalez-Martinez
OBJECTIVE Insular epilepsy is relatively rare; however, exploring the insular cortex when preoperative workup raises the suspicion of insular epilepsy is of paramount importance for accurate localization of the epileptogenic zone and achievement of seizure freedom. The authors review their clinical experience with stereoelectroencephalography (SEEG) electrode implantation in patients with medically intractable epilepsy and suspected insular involvement. METHODS A total of 198 consecutive cases in which patients underwent SEEG implantation with a total of 1556 electrodes between June 2009 and April 2013 were reviewed...
June 16, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28620718/the-phenotypic-spectrum-of-arhgef9-includes-intellectual-disability-focal-epilepsy-and-febrile-seizures
#10
Karl Martin Klein, Manuela Pendziwiat, Anda Eilam, Ronit Gilad, Ilan Blatt, Felix Rosenow, Moien Kanaan, Ingo Helbig, Zaid Afawi
Mutations or structural genomic alterations of the X-chromosomal gene ARHGEF9 have been described in male and female patients with intellectual disability. Hyperekplexia and epilepsy were observed to a variable degree, but incompletely described. Here, we expand the phenotypic spectrum of ARHGEF9 by describing a large Ethiopian-Jewish family with epilepsy and intellectual disability. The four affected male siblings, their unaffected parents and two unaffected female siblings were recruited and phenotyped. Parametric linkage analysis was performed using SNP microarrays...
June 15, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28614746/ictal-coughing-clinical-features-and-differential-diagnoses
#11
Ali A Asadi-Pooya, Leah Shabo, Dale Wyeth, Maromi Nei
PURPOSE: To describe a series of patients with ictal coughing to estimate its occurrence and characterize the clinical features and differential diagnoses. METHODS: We retrospectively reviewed all the long-term video-EEG reports from Jefferson Comprehensive Epilepsy Center over a 7-year period (2010-2016) for the occurrence of the term "cough" in the text body. All the extracted reports were reviewed and patients with at least one documented ictal coughing at the epilepsy monitoring unit (EMU) were included in the study...
June 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28606690/antiparasitic-treatment-of-neurocysticercosis-the-effect-of-cyst-destruction-in-seizure-evolution
#12
REVIEW
Hector H Garcia, Oscar H Del Brutto
Antiparasitic agents against Taenia solium cysticercosis have been in use since 1979, although its use has been questioned on the basis that cysts would die naturally and thus treatment-induced inflammation is unnecessary. In addition, isolated reports have also questioned whether neurocysticercosis (NCC) is a cause of epilepsy. After more than three and a half decades, a large body of evidence is available. Little if any doubt exists about NCC as a cause of seizures - NCC is consistently associated with seizures when appropriate groups are compared, and in a large subset of cases, seizure semiology correlates with the anatomical location of lesions...
June 9, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28605962/novel-approach-to-magnetic-resonance-imaging-of-epileptic-dogs-t2-relaxometry-of-the-brain-with-emphasised-hippocampus
#13
Borbála A Lorincz, Agustina Anson, Péter Csébi, Gábor Bajzik, Gergely Biró, Alexander Tichy, Balázs B Lorincz, Rita Garamvölgyi
Hippocampal sclerosis is the most common imaging finding of intractable human epilepsy, and it may play an important role in canine and feline epileptogenesis and seizure semiology, too. The magnetic resonance imaging (MRI) criteria of hippocampal sclerosis are T2 hyperintensity, shrinkage and loss of internal structure. The detection of these changes is often challenging by subjective visual assessment of qualitative magnetic resonance (MR) images. The recognition is more reliable with quantitative MR methods, such as T2 relaxometry...
June 2017: Acta Veterinaria Hungarica
https://www.readbyqxmd.com/read/28605633/epileptic-vs-psychogenic-nonepileptic-seizures-a-video-based-survey
#14
Danielle Wasserman, Moshe Herskovitz
Psychogenic non epileptic seizures (PNES) are present in up to 30% of patients undergoing video EEG. Delay in PNES diagnosis is an average of 7.2years. Patients are exposed to costly, hazardous medications and other iatrogenic morbidities. Our aim was to investigate the ability to correctly diagnose ES from PNES in different groups and seniorities of medical professionals based on video alone. We showed ten video episodes' recordings (5 PNES, 5 ES) to doctors and nurses from ER, Internal Medicine ward and Neurology department, and inquired about the episodes' nature...
June 9, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28595758/hypercognitive-seizures-proposal-of-a-new-term-for-the-phenomenon-forced-thinking-in-epilepsy
#15
REVIEW
C Stephani, M Koubeissi
Here we propose the term hypercognitive seizures as a descriptor for seizures that manifest as a transient mental experience of intrusive thoughts or words that do not consist mainly of reminiscence. Currently, the term forced thinking is used to describe this uncommon seizure semiology, which has also been elicited by electrical brain stimulation. The available literature on forced thinking shows discordant interpretations of its meaning, justifying the suggestion of a new descriptor. In this paper, we would like to suggest and explain the term hypercognitive seizure and argue that this type of seizure lateralizes to the dominant hemisphere...
August 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28595352/neuropsychology-outcomes-following-trephine-epilepsy-surgery-the-inferior-temporal-gyrus-approach-for-amygdalohippocampectomy-in-medically-refractory-mesial-temporal-lobe-epilepsy
#16
Mike R Schoenberg, William E Clifton, Ryan W Sever, Fernando L Vale
BACKGROUND: Surgery is indicated in cases of mesial temporal lobe epilepsy(MTLE) that are refractory to medical management. The inferior temporal gyrus (ITG) approach provides access to the mesial temporal lobe (MTL) structures with minimal tissue disruption. Reported neuropsychology outcomes following this approach are limited. OBJECTIVE: To report neuropsychological outcomes using an ITG approach to amygdalohippocampectomy (AH) in patients with medically refractory MTLE based on a prospective design...
June 8, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28593865/the-semiology-of-benign-focal-epilepsy-with-affective-symptoms
#17
Fábio A Nascimento, Márcio A Sotero de Menezes, Cristiane A Simao, Bruno T Takeshita, Samanta F Blattes da Rocha, Pedro A Kowacs
Benign focal epilepsy with affective symptoms (BFEAS) is a rare childhood epilepsy syndrome essentially characterized by "epileptic attacks with affective symptoms of a terrifying type". Since the original description, approximately 50 cases have been reported. To our knowledge, however, none of the studies included video-EEG data. Herein, we detail the electroclinical features of a neurodevelopmentally normal 9-year-old boy with epilepsy since the age of 2 years. His seizure semiology essentially consisted of nocturnal focal seizures featuring abrupt fear and autonomic phenomena (such as excessive sweating, repeated swallowing, and coughing), associated with impaired consciousness...
June 7, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28586706/lgi1-antibody-encephalitis-is-characterised-by-frequent-multifocal-clinical-and-subclinical-seizures
#18
Sidra Aurangzeb, Mkael Symmonds, Ravi K Knight, Robin Kennett, Tim Wehner, Sarosh R Irani
PURPOSE: To describe clinical and electrographic characteristics of seizures LGI1-antibody encephalitis, and their correlations with two-year outcomes. METHODS: Video-electroencephalography recordings were performed on a cohort of 16 consecutive patients with LGI1-antibodies from two UK neuroscience-centers over five-years. RESULTS: From 14 of 16 patients (13 males; age-range 53-92years), 86 faciobrachial dystonic seizures were recorded at a median frequency of 0...
May 30, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28572784/inertial-sensors-to-assess-gait-quality-in-patients-with-neurological-disorders-a-systematic-review-of-technical-and-analytical-challenges
#19
REVIEW
Aliénor Vienne, Rémi P Barrois, Stéphane Buffat, Damien Ricard, Pierre-Paul Vidal
Gait disorders are major causes of falls in patients with neurological diseases. Understanding these disorders allows prevention and better insights into underlying diseases. InertiaLocoGraphy (ILG) -the quantification of gait by using inertial measurement units (IMUs) -shows great potential to address this public health challenge, but protocols vary widely and normative values of gait parameters are still unavailable. This systematic review critically compares ILG protocols, questions features extracted from inertial signals and proposes a semeiological analysis of clinimetric characteristics for use in neurological clinical routine...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28566546/familial-aggregation-of-focal-seizure-semiology-in-the-epilepsy-phenome-genome-project
#20
Steven Tobochnik, Robyn Fahlstrom, Catherine Shain, Melodie R Winawer
OBJECTIVE: To improve phenotype definition in genetic studies of epilepsy, we assessed the familial aggregation of focal seizure types and of specific seizure symptoms within the focal epilepsies in families from the Epilepsy Phenome/Genome Project. METHODS: We studied 302 individuals with nonacquired focal epilepsy from 149 families. Familial aggregation was assessed by logistic regression analysis of relatives' traits (dependent variable) by probands' traits (independent variable), estimating the odds ratio for each symptom in a relative given presence vs absence of the symptom in the proband...
May 31, 2017: Neurology
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