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Semiology

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https://www.readbyqxmd.com/read/28202379/comprehensive-preoperative-work-up-and-surgical-treatment-of-low-grade-tumor-benign-lesion-related-temporal-lobe-epilepsy
#1
Rui Feng, Jie Hu, Jinsong Wu, Liqin Lang, Chengxin Ma, Shize Jiang, Bing Sun, Xin Gu, Li Pan
OBJECTIVE: Generally low-grade tumor/benign lesion related temporal lobe epilepsy (LGT/BL-TLE) is considered easier to treat and has better prognosis when compared to non-lesional TLE. However, multiple disputes exist in surgical management of this epilepsy entity. This study aims to discuss comprehensive preoperative work-up, surgical strategies and outcome of it. METHODS: A retrospective review of sixty LGT/BL-TLE cases which underwent comprehensive preoperative work-up and then resective surgeries was conducted...
February 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28185967/intraoperative-ct-and-nexframe-guided-placement-of-bilateral-hippocampal-based-responsive-neurostimulation-a-technical-note
#2
Kunal Gupta, Jeffrey S Raskin, Ahmed M Raslan
INTRODUCTION: Surgical resection of a lesion that correlates with seizure onset in patients with epilepsy can dramatically improve seizure burden and quality of life. For bilateral hippocampal lesions, bilateral resection comes with a risk of severe cognitive deficits. Responsive neurostimulation (RNS) devices offers a new modality to treat multifocal lesions in a reversible manner, including bilateral hippocampal stimulation. We describe technical aspects of Nexframe-assisted placement of bilateral NeuroPace mesial temporal electrodes, and case examples...
February 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28185049/developing-a-novel-epileptic-discharge-localization-algorithm-for-electroencephalogram-infantile-spasms-during-hypsarrhythmia
#3
Supachan Traitruengsakul, Laurie E Seltzer, Alex R Paciorkowski, Behnaz Ghoraani
Infantile spasms (ISS) is a devastating epileptic syndrome that affects children under the age of 1 year. The diagnosis of ISS is based on the semiology of the seizure and the electroencephalogram (EEG) background characterized by hypsarrhythmia (HYPS). However, even skilled electrophysiologists may interpret the EEG of children with ISS differently, and commercial software or existing epilepsy detection algorithms are not helpful. Since EEG is a key factor in the diagnosis of ISS, misinterpretation could result in serious consequences including inappropriate treatment...
February 9, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28165286/the-erudite-humility-of-the-historian-the-critical-epistemology-of-georges-lant%C3%A3-ri-laura
#4
Elisabetta Basso Lorini
This paper analyses the historical and epistemological work of the French psychiatrist Georges Lantéri-Laura (1930-2004) within the context of the French 'tradition' of history and philosophy of sciences, with special reference to Georges Canguilhem and Michel Foucault. After an introduction devoted to a critical survey of the most recent works on the history and historiography of psychiatry in French, the paper outlines Lantéri-Laura's approach by focusing especially on the role played by the methodological concept of 'semiology' as regards the relation between medicine and psychiatry...
February 1, 2017: History of Psychiatry
https://www.readbyqxmd.com/read/28157600/development-and-validation-of-aiims-modified-inclen-diagnostic-instrument-for-epilepsy-in-children-aged-1-month-18-years
#5
Sheffali Gulati, Harsh Patel, Biswaroop Chakrabarty, Rachana Dubey, N K Arora, R M Pandey, V K Paul, Konanki Ramesh, Vyshakh Anand, Ankit Meena
OBJECTIVES: There is shortage of specialists for the diagnosis of children with epilepsy, especially in resource limited settings. Existing INCLEN (International Clinical Epidemiology Network) instrument was validated for children aged 2-9 years. The current study validated modifications of the same including wider symptomatology and age group. METHODS: The Modified INCLEN tool was validated by a team of experts by modifying the existing tools (2-9 years) to widen the age range from 1 month to 18 years and include broader symptomatology in a tertiary care teaching hospital of North India between January and June 2015...
January 25, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28122518/dancing-with-a-seizure-a-case-report
#6
Keun Tae Kim, Kon Chu, Sang Kun Lee
BACKGROUND: Dancing is a very rare seizure semiology, and has only few case reports so far. Moreover, no case regarded as dancing with both description and video was presented. CASE PRESENTATION: A 42-year-old woman with medical intractable epilepsy showed a typical semiology of right temporal lobe epilepsy: right hand automatism and ictal speech. The following semiology, appeared during ictal and post-ictal stage, was complex, rhythmical and sequential movement...
January 25, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28117084/relevance-of-medical-semiology-in-the-technological-era
#7
F Javier Laso Guzmán
No abstract text is available yet for this article.
January 20, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28109992/acute-and-spontaneous-seizure-onset-zones-in-the-intraperitoneal-kainic-acid-model
#8
Phillip Connell, Arezou Bayat, Sweta Joshi, Mohamad Z Koubeissi
OBJECTIVE: Hippocampal monitoring is often used in the intraperitoneal kainic acid (KA) seizure model for detection and quantification of early ictal activity. Here, we investigated extra-hippocampal seizure onset zones (SOZs) in this model. METHODS: Eight male Sprague Dawley rats implanted with depth electrodes were continuously recorded during intraperitoneal KA injections until status epilepticus (SE) was induced. Another group of four rats was monitored chronically up to two weeks after emergence of spontaneous recurrent seizures...
January 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28101837/drug-exposure-and-the-risk-of-microscopic-colitis-a-critical-update
#9
Alfredo J Lucendo
A variety of luminal antigens, including a wide range of drugs, have been associated with the still little-known pathophysiology of microscopic colitis (MC), with variable evidence suggesting causality. This article aims to review the aspects related to drugs as potential triggers of MC; to discuss the most commonly identified associations between drugs and MC; and to analyze the limitations of the studies currently available. A literature search was performed in PubMed combining the search terms 'drug exposure', 'drug consumption', and 'risk factors' with 'microscopic colitis', 'lymphocytic colitis', and 'collagenous colitis', with no language restrictions...
January 18, 2017: Drugs in R&D
https://www.readbyqxmd.com/read/28087825/incidence-and-predictors-of-epilepsy-after-pediatric-arterial-ischemic-stroke
#10
Lori L Billinghurst, Lauren A Beslow, Nicholas S Abend, Michael Uohara, Laura Jastrzab, Daniel J Licht, Rebecca N Ichord
OBJECTIVE: To determine the cumulative incidence and clinical predictors of remote symptomatic seizures and epilepsy after pediatric arterial ischemic stroke (AIS). METHODS: We performed a retrospective analysis of 218 participants with neonatal AIS (NAIS), presumed perinatal AIS (PPAIS), and childhood AIS (CAIS) from a single-center prospective consecutive cohort enrolled from 2006 to 2014. Medical records were reviewed for timing, semiology, and treatment of acute symptomatic seizures, remote symptomatic seizures (RSS), and epilepsy...
January 13, 2017: Neurology
https://www.readbyqxmd.com/read/28045733/pet-mri-coregistration-in-intractable-epilepsy-and-gray-matter-heterotopia
#11
Nikhil Seniaray, Anuj Jain
A 25-year-old woman with intractable seizures underwent FDG PET/MRI for seizure focus localization. MRI demonstrated bilateral carpetlike nodular subependymal gray matter and asymmetrical focal dilatation in the right temporal horn. PET/MRI showed increased FDG within subependymal gray matter with significant hypometabolism in right anterior temporal lobe. EEG and ictal semiology confirmed the right temporal seizure origin. This case highlights the importance of identification of gray matter heterotopia on FDG PET/MRI...
March 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28043024/utility-of-a-questionnaire-tool-quaras-for-localizing-and-lateralizing-seizures-in-the-epilepsy-monitoring-unit-emu
#12
Rima M Chaudhari, Bhargavi Ramanujam, Renjith Appukuttan, Anubha Sharma, Yuvraj Kunwar, Gaurav Tejaniya, Ajay Garg, Madakasira Vasantha Padma, Madhavi Tripathi, Chandrashekhar Bal, Deepa Dash, Sarat P Chandra, Manjari Tripathi
OBJECTIVES: An accurate description of the seizure semiology improves the recognition of the ictal onset zone and helps in hypothesizing the possible epileptogenic zone (EZ). Semiology based on a reliable description of seizures may be as good as investigative modalities, as has been shown by numerous studies. The main objective of this study was to apply a questionnaire-tool for auras and semiology (QUARAS) in refractory epilepsy cohort and compare its yield to that of standard history-taking...
February 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28038490/the-ophthalmological-observations-in-caelius-aurelianus-text-on-acute-and-on-chronic-diseases
#13
REVIEW
Konstantinos Laios, Marilita Moschos, George Androutsos
Caelius Aurelianus' Latin translation, De morbis acutis et chronicis, of Soranus of Ephesus' original Greek work is a work devoted to internal medicine. Nevertheless, there are some observations about ocular pathologies which reveal the level of the knowledge at that time about the eye and their use as elements of pathological semiology.
December 2016: Acta Medico-historica Adriatica: AMHA
https://www.readbyqxmd.com/read/28027860/from-nocturnal-frontal-lobe-epilepsy-to-sleep-related-hypermotor-seizures-a-35-year-diagnostic-challenge
#14
Paolo Tinuper, Francesca Bisulli
Nocturnal frontal lobe epilepsy (NFLE) is a focal epilepsy with seizures arising mainly during sleep and characterized by complex, often bizarre, motor behavior or sustained dystonic posturing. First described in 1981, it was initially considered a motor disorder of sleep and was named nocturnal paroxysmal dystonia (NPD). The unusual seizure semiology, onset during sleep, and often uninformative scalp EEG and brain MRI make it difficult to distinguish NPD attacks from other non-epileptic nocturnal paroxysmal events, namely parasomnias...
December 15, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27988107/understanding-psychogenic-nonepileptic-seizures-phenomenology-semiology-and-the-integrative-cognitive-model
#15
Markus Reuber, Richard J Brown
Psychogenic Nonepileptic Seizures (PNES) are one of the commonest differential diagnoses of epilepsy. This paper provides a narrative review of what has been learnt in the last 25 years regarding the visible manifestations, physiological features, subjective experiences and interactional aspects of PNES. We then explore how current insights into PNES semiology and phenomenology map onto the Integrative Cognitive Model (ICM), a new account of these phenomena that unifies previous approaches within a single explanatory framework...
November 15, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27974932/correlations-between-the-semiologic-changes-and-the-imaging-aspects-in-the-lateral-bulbar-infarction
#16
Cristea I, Popa C
The study aimed to evaluate the correlations between the clinical and paraclinical data in the lateral bulbar infarction, benefiting from the access to the semiologic characteristics of a group studied and the MRI angiography, without a contrast agent, through the 3D TOF technique combined with MIP, as an imaging technique for the evaluation of the arterial lesion. The study group included 20 patients with lateral bulbar infarction, 14 men, and 6 women aged between 21 and 80 years, the mean age being 56, 9 years, who were enrolled in the study in the period 2012 and 2014, following the admission in the National Institute of Neurology and Neurovascular Diseases...
July 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27974376/navigating-the-island-of-reil-how-to-understand-the-insular-cortex
#17
EDITORIAL
Ray Wynford-Thomas, Rob Powell
Insular-onset seizures are rare and easily misdiagnosed. In this article, we aim to highlight the often distinctive semiology of seizures involving the insula with reference to three cases. We suggest three points to aid the recognition of seizures involving the insula: (1) Seizures originating in the insula frequently present with a sensation of laryngeal constriction, dyspnoea or unpleasant somatosensory symptoms; (2) Seizures involving the anterior insula may have a silent onset, but tend to propagate rapidly to motor areas causing motor or hypermotor symptoms; (3) Seizures involving the posterior insula cause somatosensory symptoms, which are normally contralateral to the seizure onset...
December 14, 2016: Practical Neurology
https://www.readbyqxmd.com/read/27919842/propagation-of-seizures-in-a-case-of-lesional-mid-cingulate-gyrus-epilepsy-studied-by-stereo-eeg
#18
Rafeed Alkawadri, Jorge Gonzalez-Martinez, Nicolas Gaspard, Andreas V Alexopoulos
Little is known about the propagation of seizures arising from the cingulate gyrus, as cingulate coverage with interhemispheric subdural electrodes is usually challenging and incomplete due to inherent anatomical and vascular limitations. We present a case of lesional mid-cingulate epilepsy confirmed by stereotactically implanted intracranial depth electrodes and subsequent surgical resection. Hypermotor symptomatology was seen during the first seven seconds of seizure onset while the seizure was still confined to the mid-cingulate gyrus contacts...
December 1, 2016: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/27918347/the-stereo-electroencephalography-the-epileptogenic-zone
#19
Jorge A Gonzalez-Martinez
The stereo-electroencephalography (SEEG) methodology and technique was developed almost 60 years ago in Europe and it has proven its efficacy and safety over the last 55 years. The main advantage of the SEEG method is the possibility to study the epileptogenic neuronal network in its dynamic and tri-dimensional aspect, with an optimal time and space correlation with the clinical semiology. In this manuscript, the technical and methodological aspects of the SEEG will be discussed focusing on the planning of SEEG implantations, technical nuances, conceptualization of the epileptogenic zone, and the different methods of SEEG-guided surgical resections and ablations...
December 2016: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/27910806/epilepsia-partialis-continua-aetiology-semiology-and-prognosis-in-a-spanish-adult-cohort
#20
Helena Bejr-Kasem, Jacint Sala-Padró, Manuel Toledo, Estevo Santamarina, Silvana Sarria, Montserrat Gonzalez-Cuevas, María Sueiras-Gil, Manolo Quintana, Xavier Salas-Puig
To describe the semiological features in patients suffering with Epilepsia Partialis Continua (EPC), also referred as Kozhevnikov syndrome and their relationship with aetiology, duration, and prognosis, as well as recurrence during follow-up. We analysed consecutive EPC patients diagnosed and followed in our centre over a seven-and-a half year period. We collected demographic and clinical data, along with neuroimaging and EEG recordings. All patients were followed for more than six months. Patients were categorised with single body area or multiple body area involvement according to the body parts affected...
December 1, 2016: Epileptic Disorders: International Epilepsy Journal with Videotape
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