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Semiology

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https://www.readbyqxmd.com/read/29929098/kcnj6-girk2-trisomy-is-not-sufficient-for-conferring-the-susceptibility-to-infantile-spasms-seen-in-the-ts65dn-mouse-model-of-down-syndrome
#1
Krutika Joshi, Lily Shen, Feng Cao, Susan Dong, Zhengping Jia, Miguel A Cortez, O Carter Snead
OBJECTIVE: Infantile spasms (IS) is a catastrophic childhood seizure disorder that is characterized by extensor and/or flexor spasms, cognitive deterioration and a characteristic EEG abnormality. The latter consists of a pattern of a spike-wave followed by an electrodecremental response (EDR), which is a flattening of the EEG waveform amplitude. The mechanism/circuitry that underpins IS is unknown. Children with Down Syndrome (DS) are particularly vulnerable to IS. The standard mouse model of DS is the Ts65Dn mutant mouse (Ts)...
June 12, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29923812/the-identification-of-torsades-de-pointes-via-ceeg-a-case-report-on-a-patient-with-physiologically-provoked-nonepileptic-events
#2
Andrew Todd Ham, Jill Mackey, Gary Semb
Continuous electroencephalography (CEEG) is chiefly performed at The Medical University of South Carolina (MUSC) for identifying seizures, including its refined use within the epilepsy monitoring unit (EMU) as a differentiator between epileptic and psychogenic etiologies. CEEG also provides critical data that carry implications outside the bounds of both epilepsy and psychogenic events, such as the characterization of unorthodox clinical phenomena that are of physiological (though nonepileptic) origins. Although nonepileptic events (NEEs) are primarily linked with psychogenic phenomena (conversion disorder, malingering) that can mimic epileptic activity, they, like seizures, have diverse semiologies and etiologies...
2018: Neurodiagnostic Journal
https://www.readbyqxmd.com/read/29914745/tracheal-bronchus-diagnosed-in-children-undergoing-flexible-bronchoscopy
#3
REVIEW
Estela Pérez Ruiz, Pilar Caro Aguilera, Ana Isabel Valdivielso, Sonia Sanchís Cárdenas, Yazmina Martínez García, Javier Pérez Frías
This paper describes the clinical features of paediatric patients with tracheal bronchus (TB) identified with flexible bronchoscopy (FB) in a tertiary care hospital. A retrospective review of every FB with diagnosis of TB carried out in our centre since 1990 was performed which considered specifically: age at diagnosis, gender, semiology, somatic anomalies, tracheal bronchus type, other bronchoscopic findings and clinical progress. Out of 1665 FB in 1337 patients, TB was found in 26 (1.9%). The median age was 15 months (age range 1 month-13 years), with no gender differences...
May 19, 2018: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/29913406/teleconference-based-education-of-epileptic-seizure-semiology
#4
Yosuke Kakisaka, Kazutaka Jin, Mayu Fujikawa, Yu Kitazawa, Nobukazu Nakasato
BACKGROUND: To evaluate whether a teleconference-based lecture provides similar understanding of seizure semiology to a face-to-face lecture for physicians. METHODS: Subjects were 66 physicians consisting of adult and pediatric neurologists, neurosurgeons, psychiatrists, and general practitioners. All attended the 30-minute lecture to introduce various types of seizure semiology using video-clips by one of the authors (Yo.K.) and then joined the comprehensive case conference which discussed three cases in 1...
June 12, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29910128/miming-neurological-syndromes-improves-medical-student-s-long-term-retention-and-delayed-recall-of-neurology
#5
Emmanuel Roze, Yulia Worbe, Céline Louapre, Aurélie Méneret, Cécile Delorme, Eavan McGovern, Marta Ruiz, Jean Capron, Raphaël Le Bouc, Stéphane Epelbaum, Sonia Alamowitch, Alexandre Duguet, Marie-Christine Renaud, Olivier Palombi, Tamara M Pringsheim, Constance Flamand-Roze, Olivier Steichen
Basic examination and diagnostic skills in neurology are important for every graduating medical student. However, a majority of medical students consider neurology as complex and difficult to master. We evaluate the impact a learner-friendly, innovative simulation-based training programme has on long-term retention and delayed recall of neurological semiology amongst third-year medical students from the University Pierre et Marie Curie in Paris, France. The 2013 class received standard teaching in neurological semiology...
June 7, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29909766/-phenomenology-clinical-diagnostics-and-treatment-of-hallucinations
#6
Daniela Hubl
Phenomenology, clinical diagnostics and treatment of hallucinations Abstract. Hallucinations are perceptions without any stimulus. They occur typically in schizophrenia, but they can be found in other psychiatric or medical disorders as well. Recently, hallucinations have been increasingly reported to occur with a high prevalence in the general population and they are conceptualised as continuum from a physiological to pathological especially psychotic phenomenon. Schizophrenic hallucinations exhibit a special proximity to language and for this they can be considered as diagnostic...
June 2018: Therapeutische Umschau. Revue Thérapeutique
https://www.readbyqxmd.com/read/29909187/epilepsia-partialis-continua-correlation-of-semiology-outcome-and-electrophysiologic-features
#7
Murat Mert Atmaca, Nerses Bebek, Elif Kocasoy-Orhan, Candan Gürses
OBJECTIVE: Epilepsia partialis continua (EPC) is a special form of cortical epilepsy. Several studies have described the ictal and interictal electroencephalography (EEG) findings in patients with EPC; however, lateralizing and localizing values of these findings have been evaluated rarely. This study investigated the correlation of semiologic and EEG findings, and outcomes in patients with EPC. PATIENTS AND METHODS: Clinical and EEG findings and outcomes, and their correlations were studied prospectively in 15 patients who were diagnosed as having EPC upon presentation to Istanbul Medical Faculty Hospital between January 2010 and April 2014, and retrospectively in 5 previously evaluated patients...
June 9, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29906696/ictal-signs-in-tuberous-sclerosis-complex-clinical-and-video-eeg-features-in-a-large-series-of-recorded-seizures
#8
Miriam Nella Savini, Alessia Mingarelli, Aglaia Vignoli, Francesca La Briola, Valentina Chiesa, Angela Peron, Roberto Mai, Laura Tassi, Massimo Mastrangelo, Elena Zambrelli, Katherine Turner, Maria Paola Canevini
Epilepsy is the most common neurological symptom in tuberous sclerosis complex (TSC), occurring in 72-85% of affected individuals. Despite the large number of patients reported, their electroclinical phenotype has been rarely described. We analyzed seizure semiology through ictal video-electroencephalography (V-EEG) recordings in a large series of patients. In this multicenter study, we reviewed V-EEGs of 51 patients: ictal recordings were analyzed in correlation with their clinical variables. The median age of epilepsy onset was six months (one day-16 years), with onset in the first year of life in 71% patients (36/51), in 10 of them during the neonatal period...
June 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29905154/high-level-visual-manifestations-of-epileptic-seizures-originating-from-the-medial-parietal-cortex
#9
Shrita Pendekanti, Sori Baek, Yagmur Basak Kilinc, Josef Parvizi
We describe the case of a patient with well-localized focal seizures originating from the medial parietal cortex. Seizures originated from area 7m, and findings revealed clear visuospatial semiological signs that may be used clinically to help diagnose similar cases of seizures in non-lesional patients.
June 15, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29905152/epileptic-seizure-semiology-in-different-age-groups
#10
Guadalupe Fernandez-Baca Vaca, Carlos L Mayor, Naira García Losarcos, Jun T Park, Hans O Lüders
Seizure semiology provides information about the eloquent cortex involved during a seizure and helps to generate a hypothesis regarding the localization of the epileptogenic zone (EZ), a prerequisite for surgical management of epilepsy. We aimed to study the seizure semiology among all different age groups to better characterize semiological changes that occur with age. We performed a retrospective review of video-EEG data in paediatric and adult patients admitted to the Epilepsy Monitoring Unit over a three-year period...
June 15, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29886184/meg-guided-analysis-of-7t-mri-in-patients-with-epilepsy
#11
A J Colon, M J P van Osch, M Buijs, J V D Grond, A Hillebrand, O Schijns, G J Wagner, P Ossenblok, P Hofman, M A V Buchem, P Boon
PURPOSE: To study possible detection of structural abnormalities on 7T MRI that were not detected on 3T MRI and estimate the added value of MEG-guidance. For abnormalities found, analysis of convergence between clinical, MEG and 7T MRI localization of suspected epileptogenic foci. METHODS: In adult patients with well-documented localization-related epilepsy in whom a previous 3T MRI did not demonstrate an epileptogenic lesion but MEG indicated a plausible epileptogenic focus, 7T MRI was performed...
May 26, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29885784/making-psychiatric-semiology-great-again-a-semiologic-not-nosologic-challenge
#12
J-A Micoulaud-Franchi, C Quiles, J-M Batail, C Lancon, M Masson, G Dumas, M Cermolacce
This article analyzes whether psychiatric disorders can be considered different from non-psychiatric disorders on a nosologic or semiologic point of view. The supposed difference between psychiatric and non-psychiatric disorders relates to the fact that the individuation of psychiatric disorders seems more complex than for non-psychiatric disorders. This individuation process can be related to nosologic and semiologic considerations. The first part of the article analyzes whether the ways of constructing classifications of psychiatric disorders are different than for non-psychiatric disorders...
June 6, 2018: L'Encéphale
https://www.readbyqxmd.com/read/29882467/a-progressive-breakdown-of-the-body-in-space
#13
Evie Kourtidou, Dimitrios Kasselimis, George Makrydakis, Lina Chatziantoniou, Andreas Kyrozis, Ioannis Evdokimidis, Constantin Potagas
A 74 year-old woman (MD), free of previous neurological history, presented with difficulty in handling cutlery, clothes, writing with what was initially described as an atypical apraxia in acts related to space. Initial neurological evaluation revealed mixed, asymmetric pyramidal, and extrapyramidal semiology. Νeuropsychological testing revealed dressing and constructional deficits, ideomotor apraxia and signs of executive dysfunction in absence of memory, language, and visual perception pathology. The final diagnosis was that of a corticobasal degeneration, where the rare occurrence of a progressively emerging syndrome of self-management loss within peripersonal space is observed...
June 8, 2018: Neurocase
https://www.readbyqxmd.com/read/29882051/burned-bodies-post-mortem-computed-tomography-an-essential-tool-for-modern-forensic-medicine
#14
REVIEW
J-B Coty, C Nedelcu, S Yahya, V Dupont, C Rougé-Maillart, M Verschoore, C Ridereau Zins, C Aubé
Currently, post-mortem computed tomography (PMCT) has become an accessible and contemporary tool for forensic investigations. In the case of burn victims, it provides specific semiologies requiring a prudent understanding to differentiate between the normal post-mortem changes from heat-related changes. The aim of this pictorial essay is to provide to the radiologist the keys to establish complete and focused reports in cases of PMCT of burn victims. Thus, the radiologist must discern all the contextual divergences with the forensic history, and must be able to report all the relevant elements to answer to the forensic pathologist the following questions: Are there tomographic features that could help to identify the victim? Is there evidence of remains of biological fluids in liquid form available for toxicological analysis and DNA sampling? Is there another obvious cause of death than heat-related lesions, especially metallic foreign bodies of ballistic origin? Finally, what are the characteristic burn-related injuries seen on the corpse that should be sought during the autopsy? TEACHING POINTS: • CT is highly useful to find features permitting the identification of a severely burned body...
June 7, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29869478/-about-a-cresol-intoxication
#15
S Fatihi, P Mols
Cresols are phenol derivatives commonly used as surface disinfectants. Ingestion may cause local mucocutaneous damage and extensive systemic toxicity : central nervous, cardiovascular, hematological, hepatic, renal and pulmonary. We describe the case of a 33-year-old woman who swallowed, without suicidal intent, 50 to 70 cm3 of a 50% cresol solution. Coma occurred within 5 minutes of ingestion, she presented a bradypnea with desaturation, and the SMUR team performed on-site an orotracheal intubation. On arrival at the hospital, the patient had typical caustic lesions around her mouth...
May 30, 2018: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/29858947/double-match-of-18-f-fluorodeoxyglucose-pet-and-iomazenil-spect-improves-outcomes-of-focus-resection-surgery
#16
Ayataka Fujimoto, Tohru Okanishi, Sotaro Kanai, Keishiro Sato, Shinji Itamura, Shimpei Baba, Mitsuyo Nishimura, Takayuki Masui, Hideo Enoki
BACKGROUND: When the results of electroencephalography (EEG), magnetic resonance imaging (MRI), and seizure semiology are discordant or no structural lesion is evident on MRI, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are important examinations for lateralization or localization of epileptic regions. We hypothesized that the concordance between interictal 2-[18 F]fluoro-2-deoxy-D-glucose (18 FDG)-PET and iomazenil (IMZ)-SPECT could suggest the epileptogenic lobe in patients with non-lesional findings on MRI...
June 1, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29796773/bilateral-bow-hunter-s-syndrome-mimicking-a-classic-seizure-semiology
#17
Asher J Albertson, Terrance T Kummer
No abstract text is available yet for this article.
May 23, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29791879/seizure-imitators-monitored-using-video-eeg-in-children-with-intellectual-disabilities
#18
Riyo Ueda, Yuko Shimizu-Motohashi, Kenji Sugai, Eri Takeshita, Akihiko Ishiyama, Takashi Saito, Hirofumi Komaki, Eiji Nakagawa, Masayuki Sasaki
Diagnosis of seizure imitators in children is often challenging, and individuals with intellectual disability (ID) could be at additional risk of seizure imitator misdiagnosis. We aimed to elucidate distinct features of clinical semiology among children of different intellectual levels, which may help in distinguishing seizure imitators from epilepsy in such individuals. We retrospectively compared semiological features of seizure imitators in children with and without ID captured using video-electroencephalography (video-EEG)...
May 20, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29786809/-diagnosing-epileptic-seizures-and-epilepsy
#19
Kristina Malmgren, Tommy Stödberg, Åsa Amandusson, Maria Strandberg
There are many episodic conditions which may be confused with epileptic seizures. The diagnosis of epileptic seizures is still dependent on a good history and witness report, as well as good knowledge of seizure semiology, and of the symptoms of a variety of differential diagnostic conditions. The principal differential diagnoses in adults and children are outlined in this review. The diagnostic problems do not exist only initially, so it is important to reconsider the diagnosis when deemed relevant. The possibility of home video recordings of recurring attacks may be helpful...
May 21, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29775765/disconnection-surgery-for-intractable-epilepsy-with-a-structural-abnormality-in-the-medial-posterior-cortex
#20
Takeshi Matsuo, Kensuke Kawai, Kenji Ibayashi, Ichiro Shirouzu, Miki Sato
BACKGROUND: The lesionectomy is a general surgical procedure for treating focal epilepsy resulting from a structural abnormality, but some patients can not achieve favorable outcome, especially patients whose symptomatogenic zone is located in remote regions. Herein we propose the surgical disconnection of the seizure propagation pathway, which consists of short and long associating fibers linking the epileptogenic zone to the remote symptomatogenic zone, as an effective method of achieving favorable seizure outcomes in patients with posterior cortex epilepsy...
May 15, 2018: World Neurosurgery
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