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Odontogenic tumor

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https://www.readbyqxmd.com/read/28316917/a-comparative-study-of-syndecan-1-expression-in-different-odontogenic-tumors
#1
Shahroo Etemad-Moghadam, Mojgan Alaeddini
BACKGROUND: Expression of various cellular/molecular factors change during the course of tumor formation from odontogenic tissues of the tooth germ. Evaluation of these factors can help provide a better perception of the tumorigenesis and biologic behavior of odontogenic tumors (OTs). Syndecan-1 is a heparan sulfate proteoglycan which has not been extensively investigated in these lesions. The objective of the present study was to assess the immunohistochemical expression of CD138 in adenomatoid odontogenic tumor (AOT), ameloblastic fibroma (AF) and odontogenic myxoma (OM) and to compare it with ameloblastoma and keratocystic odontogenic tumor (KCOT)...
January 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28302237/extra-osseous-odontogenic-myxoma-of-maxillary-gingiva
#2
Manas Bajpai, Nilesh Pardhe
Odontogenic myxomas are rare odontogenic tumors of jaw characterised by accumulation of mucoid ground substance with little collagen. Peripheral odontogenic myxoma (POM) is extra-osseous variant of odontogenic myxomas, occurring solely in the soft tissue covering the tooth bearing portion of jaws. POM is exceedingly rare, less than 10 cases have been published till date. A case of POM is reported here in a 27-year female which was provisionally diagnosed as pyogenic granuloma.
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28291396/mandibular-reconstruction-by-using-a-liquid-nitrogen-treated-autograft-in-a-dog-with-an-oral-tumor
#3
Yasuhiko Okamura, Kazuki Heishima, Tomoki Motegi, Jun Sasaki, Masanobu Goryo, Hideji Nishida, Hiroyuki Tsuchiya, Masaaki Katayama, Yuji Uzuka
A 10 yr old intact female German shepherd dog presented with a large peripheral odontogenic fibroma and malignant melanoma on her lower jaw. The tumor was resected with a unilateral subtotal rostral hemimandibulectomy. After the mandible was removed, it was devitalized intraoperatively by freezing it in liquid nitrogen. It was subsequently reimplanted. New bone tissue formed in the gap between the frozen bone and the host bone. The regenerated bone contained osteocytes, osteoblasts, and blood vessels. The cosmetic appearance of the dog was preserved...
March 14, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28289810/non-odontogenic-tumors-of-the-facial-bones-in-children-and-adolescents-role-of-multiparametric-imaging
#4
REVIEW
Minerva Becker, Salvatore Stefanelli, Anne-Laure Rougemont, Pierre Alexandre Poletti, Laura Merlini
Tumors of the pediatric facial skeleton represent a major challenge in clinical practice because they can lead to functional impairment, facial deformation, and long-term disfigurement. Their treatment often requires a multidisciplinary approach, and radiologists play a pivotal role in the diagnosis and management of these lesions. Although rare, pediatric tumors arising in the facial bones comprise a wide spectrum of benign and malignant lesions of osteogenic, fibrogenic, hematopoietic, neurogenic, or epithelial origin...
March 13, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28286639/calcifying-cystic-odontogenic-tumor-in-radiologically-normal-dental-follicular-space-of-mandibular-third-molars-report-of-two-cases
#5
Gargi S Sarode, Sachin C Sarode, Ghevaram Prajapati, Mahesh Maralingannavar, Shankargouda Patil
Two cases of calcifying cystic odontogenic tumor (CCOT) of the dental follicle in an impacted third molar without clinical and radiological evidence are reported during routine histopathological examination. In both the cases left mandibular third molar was mesioangularly impacted with pericoronal radiolucency of less than 2.5 mm, which was not indicative of any pathology. As a routine protocol (which is not practiced widely) of our institution, dental follicles associated with extracted molars were sent for histopathological examination...
January 11, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/28273221/keratocystic-odontogenic-tumor
#6
Brenda DE Souza Moura, Maria Aparecida Cavalcante, Wagner Hespanhol
to evaluate the frequency of keratocystic odontogenic tumor (KOT) in the Oral Surgery Service (OSS) of the University Hospital Clementino Fraga Filho of the Federal University of Rio de Janeiro (HUCFF / UFRJ), with respect to recurrence rate, gender, age of recurrence and location of the injury Methods: clinical records were reviewed and histopathological reports of KOT patients of the HUCFF/UFRJ between 2002 and 2012. Patients diagnosed with KOT were divided into two groups for the occurrence of relapse: positive (n=6) and negative (n=19) Results: regarding the location, there was a predilection for the mandible...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28272664/desmoplastic-fibroblastoma-in-maxillary-alveolar-bone-mimicking-an-odontogenic-lesion-a-novel-case-report-with-review-of-literature
#7
Zohreh Jaafari-Ashkavandi, Mehdi Yasamin Shirazi, Sepideh Assar
Desmoplastic fibroblastoma (Collagenous fibroma) is a rare benign soft tissue tumor that disseminates widely and can be intramuscular or subcutaneously. There are seven reported cases in the oral cavity so far. We reported a novel case of collagenous fibroma that has been found in the anterior part of maxilla in a 58-year-old woman as an intraosseous radiolucent lesion that has been discovered during routine radiography. Histopathologically, spindle and stellate-shaped fibroblasts in a collagen-rich stroma as well as binucleated and multinucleated fibroblasts with prominent nucleoli were seen...
February 4, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28247226/update-from-the-4th-edition-of-the-world-health-organization-classification-of-head-and-neck-tumours-odontogenic-and-maxillofacial-bone-tumors
#8
John M Wright, Marilena Vered
The 4th edition of the World Health Organization's Classification of Head and Neck Tumours was published in January of 2017. This article provides a summary of the changes to Chapter 4 Tumours of the oral cavity and mobile tongue and Chapter 8 Odontogenic and maxillofacial bone tumours. Odontogenic cysts which were eliminated from the 3rd 2005 edition were included in the 4th edition as well as other unique allied conditons of the jaws. Many new tumors published since 2005 have been included in the 2017 classification...
March 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28238093/role-of-hif-1%C3%AE-and-caspase-3-in-cystogenesis-of-odontogenic-cysts-and-tumors
#9
Natacha M M da Costa, Adriane S de Siqueira, André L R Ribeiro, Maria S da Silva Kataoka, Ruy G Jaeger, Sérgio M de Alves-Júnior, Andrew M Smith, João de Jesus Viana Pinheiro
OBJECTIVES: Odontogenic cysts and tumors are the most relevant lesions that affect the gnathic bones. These lesions have in common the formation of cystic areas and this common feature may suggest involvement of similar mechanisms. The hypoxia inducible factor 1 alpha (HIF-1α), a responsive protein to hypoxia and caspase-3, an irreversible apoptosis marker, may contribute to cyst formation. Thus, this study aimed to investigate the immunoexpression of these proteins in odontogenic cysts and tumors...
February 25, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28222389/correlation-between-ploidy-status-using-flow-cytometry-and-nucleolar-organizer-regions-in-benign-and-malignant-epithelial-odontogenic-tumors
#10
Sarah Ahmed Mohamed Mahmoud, Dalia Hussein El-Rouby, Safa Fathy Abd El-Ghani, Omnia Mohamed Badawy
OBJECTIVE: Differentiation between the aggressive benign odontogenic tumors and their malignant counterparts is controversial and difficult. While flow cytometry (FCM) allowed DNA analysis in neoplasia, argyrophilic organizer regions (AgNORs) number and/or size in a nucleus are correlated with the ribosomal gene activity and therefore with cellular proliferation. The aim of this research was to study the diagnostic accuracy of FCM and AgNORs staining in differentiating between benign and malignant epithelial odontogenic tumors and to correlate between these two interventions...
February 14, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28212886/primary-ameloblastoma-of-the-temporal-bone
#11
Andro Košec, Jakov Ajduk, Mihael Ries, Robert Trotić
Ameloblastoma is a locally aggressive tumor derived from odontogenic epithelium. Although benign, its clinical behavior can often exhibit malignant characteristics. It is marked by slow and persistent growth with infiltration of adjacent tissues. Almost 70% occur in the mandible in patients older than 30 years. Recurrence of ameloblastoma from inadequate treatment is frequent. Because of its slow growth, recurrences can present decades after primary surgery. A primary ameloblastoma in an area outside the mandibular, maxillary, and infratemporal fossa regions has not been described in detail to date, with only 1 possible case mentioned in the literature...
January 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28209160/odontogenic-tumors-in-ethiopia-eight-years-retrospective-study
#12
Bruktawit Kebede, Dawit Tare, Birke Bogale, Fessahaye Alemseged
BACKGROUND: Odontogenic tumor (OT) comprises a large heterogeneous group of lesions arising from tooth producing tissues or its remnants. Studies on OTs are scarce in Ethiopia. Thus, the present study aimed to assess the pattern of OTs in Ethiopia. METHODS: An 8 years retrospective study was conducted at the Dental and Maxillofacial Department, St. Paul's referral hospital, Addis Ababa, Ethiopia. Data were collected by reviewing the medical records of patients who visited the Department from September 2008 to August 2015...
February 16, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28199753/tnf-%C3%AE-308g-a-and-tnf-r1-36a-g-single-nucleotide-polymorphisms-are-strong-risk-factors-for-odontogenic-keratocystic-tumor-development
#13
Branislav Ilic, Nadja Nikolic, Miroslav Andric, Drago Jelovac, Biljana Milicic, Tanja Jozic, Slobodan Krstic, Jelena Milasin
BACKGROUND: Polymorphisms in genes encoding tumor necrosis factor-α (TNF-α) and its receptor TNF-R1 have been shown to affect one person's susceptibility to develop certain neoplastic diseases. The aim of the present association study was to investigate whether single nucleotide polymorphisms (SNPs) in TNF-α (-308G>A) and TNF-R1 (36A>G) genes modulate the susceptibility for keratocystic odontogenic tumors (KCOTs) development in Serbian patients. METHODS: Genotyping was performed in 60 KCOT patients and 125 healthy individuals, using polymerase chain reaction/restriction fragment length polymorphism analysis...
February 15, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28191811/metastatic-ameloblastoma-to-brain-a-rare-entity
#14
Arif Sarmast, Khursheed Nayil-M, Rumana Makhdoomi, Azhar Butto, Altaf Ramzan
Ameloblastoma is a rare odontogenic tumor of the jaw. It is a benign neoplasm but local recurrence is common. Metastasis from this tumor is all the more rare. The commonest site for metastasis is lung. Brain is a very uncommon site of involvement. Overall prognosis is good. We hereby discuss ameloblastoma of lower jaw in a young adult which had metastasized to brain. Patient was operated for the metastatic lesion of brain and is doing well on follow-up.
September 2016: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28190584/the-effects-of-m1-and-m2-macrophages-on-odontogenic-differentiation-of-human-dental-pulp-cells
#15
Hee Chul Park, Hongxuan Quan, Tingting Zhu, Yongjoon Kim, Bongju Kim, Hyeong-Cheol Yang
INTRODUCTION: M1 (classically activated) and M2 (alternatively activated) macrophages are known to play primary roles in inflammation and tissue regeneration. To investigate the role of macrophages in dentin regeneration, this study examined the effects of M1 and M2 macrophages on the odontogenic/osteogenic differentiation of human dental pulp cells (HDPCs) using the conditioned media (CM) of the activated human monocyte cell line THP-1. METHODS: M1 and M2 macrophages were induced by lipopolysaccharide/interferon-γ and interleukin-4, respectively, and the phenotypes were confirmed by flow cytometry...
April 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28187891/automated-classification-of-maxillofacial-cysts-in-cone-beam-ct-images-using-contourlet-transformation-and-spherical-harmonics
#16
Fatemeh Abdolali, Reza Aghaeizadeh Zoroofi, Yoshito Otake, Yoshinobu Sato
BACKGROUND AND OBJECTIVE: Accurate detection of maxillofacial cysts is an essential step for diagnosis, monitoring and planning therapeutic intervention. Cysts can be of various sizes and shapes and existing detection methods lead to poor results. Customizing automatic detection systems to gain sufficient accuracy in clinical practice is highly challenging. For this purpose, integrating the engineering knowledge in efficient feature extraction is essential. METHODS: This paper presents a novel framework for maxillofacial cysts detection...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28174367/collagen-and-its-role-in-predicting-the-biological-behavior-of-odontogenic-lesions
#17
Pavan G Kulkarni, M Aruna Kumari, Abhishek Jahagirdar, Srk Nandan, Shyam Prasad Reddy D, M Keerthi
INTRODUCTION: Odontogenic cysts and tumors have variable recurrence rates. Recurrence rate is mainly due to the activity of the epithelium. The epithelium of these lesions has been investigated extensively in regard to their role in proliferative and aggressive behavior of the lesions. However, the role of the connective tissue wall in their behavior has not been studied as extensively. Collagen is an essential part of the connective tissue as a whole and fibrous wall of cystic lesions especially...
February 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28160576/the-relative-frequency-of-odontogenic-tumors-a-study-of-376-cases-in-a-brazilian-population
#18
R Lima-Verde-Osterne, E Turatti, R Cordeiro-Teixeira, R Barroso-Cavalcante
BACKGROUND: Odontogenic tumors (OTs) are rare lesions, exclusive of the jaws, that are derived from epithelial and/or ectomesenchymal elements of the tooth-forming apparatus. Their biological behavior is heterogeneous, including hamartomatous tissue proliferation, benign nonaggressive and aggressive neoplasms, and malignant tumors with metastatic capacity. The aim of this study was to describe the relative frequency of odontogenic tumors in a Brazilian population. In addition, a review of the literature identified studies on odontogenic tumors that follow the 2005 World Health Organization...
March 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28153133/odontogenic-cysts-and-neoplasms
#19
REVIEW
Elizabeth Ann Bilodeau, Bobby M Collins
This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and diagnostic pitfalls are addressed for inflammatory cysts (periapical cyst, mandibular infected buccal cyst/paradental cyst), developmental cysts (dentigerous, lateral periodontal, glandular odontogenic, orthokeratinized odontogenic cyst), benign tumors (keratocystic odontogenic tumor, ameloblastoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma and fibroodontoma, odontoma, squamous odontogenic tumor, calcifying cystic odontogenic tumor, primordial odontogenic tumor, central odontogenic fibroma, and odontogenic myxomas), and malignant tumors (clear cell odontogenic carcinoma, ameloblastic carcinoma, ameloblastic fibrosarcoma)...
March 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/28149484/maxillary-peripheral-keratocystic-odontogenic-tumor-a-clinical-case-report
#20
María Del Carmen Vázquez-Romero, María de Los Angeles Serrera-Figallo, Javier Alberdi-Navarro, Javier Cabezas-Talavero, Manuel-María Romero-Ruiz, Daniel Torres-Lagares, Jose-Manuel Aguirre-Urizar, Jose-Luis Gutiérrez-Pérez
The keratocystic odontogenic tumor is a benign odontogenic cystic neoplasia characterized by its thin, squamous epithelium with superficial parakeratosis. It has the potential for infiltration and local aggressiveness and has a high rate of recurrence. This neoplasia is predominantly found in males and people of white origin. The mandible is the most frequently involved site, in particular the third molar region, mandibular angle, and ramus. It has a mandible-maxilla ratio of 2:1. Only about twenty cases of peripheral keratocystic odontogenic tumors (PKCOT) have been reported in the international literature...
January 2017: Journal of Clinical and Experimental Dentistry
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