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Odontogenic tumor

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https://www.readbyqxmd.com/read/29351036/crouzon-with-acanthosis-nigricans-and-odontogenic-tumors-a-rare-form-of-syndromic-craniosynostosis
#1
Wen Xu, Donna M McDonald-McGinn, Alexandra J Melchiorre, Elaine H Zackai, Scott P Bartlett, Jesse A Taylor
Crouzon syndrome with acanthosis nigricans (CAN) is caused by a mutation in the fibroblast growth factor receptor ( FGFR) 3 gene that presents clinically as Crouzonoid craniofacial features in association with other anomalies such as acanthosis nigricans and benign odontogenic tumors. Diagnosis through the use of genetic mutational analysis is critical, as it alerts the surgeon to the need for careful screening for jaw tumors so that timely treatment in the form of curettage or segmental resection can be provided...
February 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29344160/the-role-of-computed-tomography-and-magnetic-resonance-imaging-in-diagnosing-clear-cell-ameloblastoma-a-case-report
#2
Shoko Gamoh, Masahiro Wato, Hironori Akiyama, Kaname Tsuji, Hiroki Ishikawa, Kaori Naruse, Hiroaki Yoshida, Shosuke Morita, Akio Tanaka, Kimishige Shimizutani
Ameloblastoma is the most common and clinically relevant type of odontogenic tumor. Clear cell odontogenic carcinoma is histologically characterized by solid sheets and nests of clear cells, whereas clear cell ameloblastoma (CCAM) is histologically characterized by an ameloblastomatous component intermixed with an extensive clear cell component. A total of 12 reports have been published on the histological etiology for CCAM; however, no reports have made regarding the detailed computed tomography and/or magnetic resonance imaging features of tumors of this type...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29340482/clear-cell-odontogenic-carcinoma-of-the-mandible-a-treatment-strategy
#3
Sabrina Ferreira, Leonardo Perez Faverani, Gabriel Mulinari Dos Santos, Everton Pontes Martins, Idelmo Rangel Garcia Júnior
Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic tumor of the jaws, histologically characterized by the presence of agglomerates of cells with eosinophilic cytoplasm. The patient, a 62-year-old Caucasian woman, presented an intraosseous lesion in the mandibular symphysis. A clinical examination revealed a discrete volumetric increase with a hard consistency, palpable to extraoral and intraoral examinations. Imaging studies revealed an extensive radiolucent area, without defined limits, extending from the region of the right second premolar to the left canine...
January 15, 2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29336289/management-of-odontogenic-cysts-by-endonasal-endoscopic-techniques-a-systematic-review-and-case-series
#4
Michael J Marino, Amber Luong, William C Yao, Martin J Citardi
BACKGROUND: Odontogenic cysts and tumors of the maxilla may be amendable to management by endonasal endoscopic techniques, which may reduce the morbidity associated with open procedures and avoid difficult reconstruction. OBJECTIVE: To perform a systematic review that evaluates the feasibility and outcomes of endoscopic techniques in the management of different odontogenic cysts. A case series of our experience with these minimally invasive techniques was assembled for insight into the technical aspects of these procedures...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29334213/conservative-management-of-ovarian-fibroma-in-a-case-of-gorlin-goltz-syndrome-comorbid-with-endometriosis
#5
Sepideh Khodaverdi, Leila Nazari, Abolfazl Mehdizadeh-Kashi, Mansoureh Vahdat, Samaneh Rokhgireh, Ali Farbod, Banafsheh Tajbakhsh
Ovarian fibromas are the most common benign solid ovarian tumors, which are often difficult to diagnose preoperatively. Ovarian fibromas, especially in bilateral cases, may be cases of Gorlin-Goltz syndrome (GGS), a rare autosomal dominant disorder with predisposition to basal cell carcinomas (BCCs) and other various benign and malignant tumors. This case report describes a 25 year-old female with GGS, bilateral ovarian fibroma, endometriosis and septated uterus, which was referred to the Gynecology Clinic of Rasoul-e-Akram Hospital in October 2016...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29333372/ghost-cell-odontogenic-carcinoma-on-right-mandible-and-its-respective-surgical-reconstruction-a-case-report
#6
Sang Yoon Park, Joonhyoung Park, Do Hyun Kwon, Jae Ho Jeon, Soung Min Kim, Hoon Myoung, Jong Ho Lee
Calcifying cystic odontogenic tumor (CCOT) is defined as an odontogenic cyst-like benign neoplasm that characteristically contains several ghost cells, ameloblastoma-like epithelium, and occasional calcification. Ghost cell odontogenic carcinoma (GCOC), a malignant form of CCOT, is an exceptionally rare malignant tumor. In this report, we present a case of a 53-year-old man whose chief complaint was a solitary mass on the right mandible area. The mass was completely removed through an extraoral surgical approach and reconstructive surgery was performed in two phases...
December 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/29311424/jaw-bones-regeneration-using-mesenchymal-stem-cells-a-single-center-experience
#7
Walter Colangeli, Umberto Riccelli, Amerigo Giudice, Ida Barca, Davide Caruso, Daniela Novembre, Claudio Tortosa, Raffaella Cordaro, Maria Giulia Cristofaro
PURPOSE: Mesenchymal stem cells (MSC), which are multipotent stromal cells, are considered to be a promising resource in tissue engineering and tissue regeneration. MSCs have been used to generate new maxillary bone with clinically successful results. The aim of this study was to determine the role of MSC in bone regeneration procedures in patients with benign maxillary lesions. METHODS: A study was conducted on five patients treated for maxillary bone defects resulting from biopsy of benign lesions at the University Hospital of Magna Græcia, Catanzaro, Italy from January 2015 to October 2016...
December 21, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29311021/squamous-odontogenic-tumor-and-squamous-odontogenic-tumor-like-proliferations-in-odontogenic-cysts-an-updated-analysis-of-170-cases-reported-in-the-literature
#8
REVIEW
Bruno Ramos Chrcanovic, Ricardo Santiago Gomez
PURPOSE: To integrate the available data published on squamous odontogenic tumors (SOT) and squamous odontogenic tumor-like proliferations in odontogenic cysts (SOT-LPOC) into a comprehensive analysis of their clinical/radiologic features. MATERIALS AND METHODS: An electronic search was undertaken in January 2017. Eligibility criteria included publications having enough clinical/radiological/histological information to confirm a definite diagnosis. RESULTS: A total of 74 publications reporting 110 SOTs (102 central, 8 peripheral) and 60 SOT-LPOC were included...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29310033/epigenetic-mechanisms-in-odontogenic-tumors-a-literature-review
#9
REVIEW
Jorge Sandoval-Basilio, Rogelio González-González, Ronell Bologna-Molina, Mario Isiordia-Espinoza, Gabriela Leija-Montoya, Sofia L Alcaraz-Estrada, Idanya Serafín-Higuera, Javier González-Ramírez, Nicolás Serafín-Higuera
OBJECTIVE: Epigenetic mechanisms, such as DNA methylation, regulate important biological processes as gene expression and it was suggested that these phenomena play important roles in the carcinogenesis and tumor biology. The aim of this review is to provide the current state of knowledge about epigenetic alterations, focusing mainly on DNA methylation, reported in odontogenic tumors. DESIGN: Literatures were searched based in the combination of the following keywords: odontogenic tumors, epigenetics, DNA methylation, histone modifications, non-coding RNA, microRNA, DNA methyltransferases...
December 30, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29303131/benign-tumors-and-tumor-like-lesions-of-the-oral-cavity-and-jaws-an-analysis-of-709-cases
#10
A Kilinc, N Saruhan, B Gundogdu, E Yalcin, U Ertas, G Urvasizoglu
PURPOSE: The purpose was to examine the prevalence, gender, age and site(s) of odontogenic and nonodontogenic benign tumors, and tumor-like lesions occurring in the oral cavity and jaws in a Turkish population, particularly, in the Eastern Turkey, and to compare findings of this study with other reports. MATERIALS AND METHODS: The data were collected from the files of the Department of Oral and Maxillofacial Surgery and the Department of Oral Pathology, Ataturk University, Turkey, during a 10-year period from January 2005 to January 2015...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29302284/adenomatoid-odontogenic-tumor-case-series-of-14-with-wide-range-of-clinical-presentation
#11
Fatima Al-Shimari, Srinivasa Chandra, Dolphine Oda
Background: To present 14 cases of adenomatoid odontogenic tumor (AOT), highlighting their clinical, radiographic, and histologic characteristics. Material and Methods: Fourteen cases of AOT were retrieved from the archives of the Oral Pathology Biopsy Service (OPBS). Clinical, radiologic, and histologic findings are described. Results: Fourteen AOT cases were reviewed, of which 12 were intraosseous and two were peripheral (gingiva). The cases came from eight females and six males with an age range of 11-30...
November 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29279565/the-effects-of-marsupialization-on-bone-regeneration-adjacent-to-keratocystic-odontogenic-tumors-and-the-mechanisms-involved
#12
Xiang Hu, Yi Zhao, Qi-Wen Man, Rui-Fang Li, Bing Liu, Yi-Fang Zhao
Bone resorption in the jaws is one of the most severe complications of keratocystic odontogenic tumors (KCOTs), and can be treated by either enucleation or marsupialization. However, the effects of marsupialization on bone regeneration adjacent to KCOTs, and the mechanisms involved, are still unclear. In this study, samples of 27 KCOTs were collected (20 before marsupialization and 7 after marsupialization) to detect the expression of bone regeneration-related molecules adjacent to KCOTs by immunohistochemistry and real-time quantitative polymerase chain reaction (qPCR)...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/29277811/ptch1-germline-mutations-and-the-basaloid-follicular-hamartoma-values-in-the-tumor-spectrum-of-basal-cell-carcinoma-syndrome-nbccs
#13
Giovanni Ponti, Marco Manfredini, Lorenza Pastorino, Monia Maccaferri, Aldo Tomasi, Giovanni Pellacani
BACKGROUND/AIM: Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominantly inherited disorder characterized by multiple basal cell carcinomas (BCC), odontogenic tumors and various skeletal anomalies. Basaloid follicular hamartomas (BFHs) constitute rare neoplasms that can be detected in sporadic and familial settings as in the Basaloid Follicular Hamartoma Syndrome (BFHS). Although BFHS shares clinical, histopathological and genetic overlapping with the NBCCS, they are still considered two distinctive entities...
January 2018: Anticancer Research
https://www.readbyqxmd.com/read/29274153/oral-cancer-a-multicenter-study
#14
K Dhanuthai, S Rojanawatsirivej, W Thosaporn, S Kintarak, A Subarnbhesaj, M Darling, E Kryshtalskyj, C-P Chiang, H-I Shin, S-Y Choi, S-S Lee, P-A Shakib
BACKGROUND: To determine the prevalence and clinicopathologic features of the oral cancer patients. MATERIAL AND METHODS: Biopsy records of the participating institutions were reviewed for oral cancer cases diagnosed from 2005 to 2014. Demographic data and site of the lesions were collected. Sites of the lesion were subdivided into lip, tongue, floor of the mouth, gingiva, alveolar mucosa, palate, buccal/labial mucosa, maxilla and mandible. Oral cancer was subdivided into 7 categories: epithelial tumors, salivary gland tumors, hematologic tumors, bone tumors, mesenchymal tumors, odontogenic tumors, and others...
December 23, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29274152/the-epidemiology-treatment-and-complication-of-ameloblastoma-in-east-indonesia-6-years-retrospective-study
#15
M Ruslin, F-N Hendra, A Vojdani, D Hardjosantoso, M Gazali, A Tajrin, J Wolff, T Forouzanfar
BACKGROUND: Ameloblastoma is a neoplasm classified as a benign epithelial odontogenic tumor of the jaws, grow slowly and are locally invasive. The aim of the present study was to investigate the incidence, treatment, and complication of patients with ameloblastoma in East-Indonesia during six years retrospective study. MATERIAL AND METHODS: This retrospective study included 84 patients who were diagnosed with ameloblastoma from 2011 to 2016. There were 56 patients with treatment data available...
December 23, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29250680/granular-ameloblastoma-report-of-two-cases-with-atypical-cytological-aspects
#16
Shelly Arora, Aadithya Basavaraj Urs, Priya Kumar, Jeyaseelan Augustine, Ravindra Kumar Saran
Ameloblastoma is an aggressive odontogenic tumor, which arises from odontogenic epithelium. Ameloblastomas can present in several clinical and histomorphological patterns. The granular cell variant accounts for only 3.5% to 5% of ameloblastomas. We have presented two cases of granular cell ameloblastoma (GCA) occurring in a 44-year-old and 50-year-old man, respectively. Case No. 1 on incisional biopsy was diagnosed as unicystic ameloblastoma (UA), which later after excisional biopsy was finally diagnosed as GCA owing to the features observed in excisional biopsied tissue...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/29247621/peripheral-ameloblastoma-a-study-of-18-cases-and-usage-of-ber-ep4-immunohistochemistry-to-rule-out-a-diagnosis-of-intraoral-basal-cell-carcinoma
#17
Jasbir D Upadhyaya, Indraneel Bhattacharyya, Sarah G Fitzpatrick, Donald M Cohen, Mohammed N Islam
PURPOSE: Peripheral ameloblastoma (PA) is a rare odontogenic tumor arising in the mucosa of tooth-bearing areas of the jaws that typically shows no radiographic evidence of bone involvement. It bears close histologic resemblance to intraoral basal cell carcinoma (IOBCC), an extremely rare entity. In our experience from previous published data, 3 cases of IOBCC were initially misdiagnosed as PA and were later differentiated from PA on the basis of Ber-EP4 protein expression. This unusual but significant experience set the premise for us to rule out a diagnosis of IOBCC by evaluating Ber-EP4 expression in all previously diagnosed cases of PA from the University of Florida Oral Pathology (UFOP) biopsy service archives...
November 23, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29238382/a-case-of-central-mucoepidermoid-carcinoma-associated-with-dentigerous-cyst
#18
Sayed Mohammad Razavi, Roya Yahyaabadi, Saeedeh Khalesi
Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland neoplasm. Central MEC (CMEC) is a rare primary intraosseous bony lesion with an incidence of 2%-4.3% of all MECs reported. In this article, we present a rare case of a CMEC in the anterior region of maxilla at a 43-year-old female patient that was arising from a dentigerous cyst. CMECs are extremely rare tumor. They are usually low-grade lesions with favorable prognosis. Odontogenic cysts are one of the origins of this lesion. Treatment of impacted tooth is necessary in the early stage for prevention of this neoplasm...
November 2017: Dental Research Journal
https://www.readbyqxmd.com/read/29233700/volumetric-analysis-of-keratocystic-odontogenic-tumors-and-non-neoplastic-jaw-cysts-comparison-and-its-clinical-relevance
#19
Martin Kauke, Ali-Farid Safi, Andrea Grandoch, Hans-Joachim Nickenig, Joachim Zöller, Matthias Kreppel
The keratocystic odontogenic tumor (KCOT) is capable of causing vast osseous destruction. Histopathological examination is pivotal for diagnosis. The diagnostic process can sometimes be hindered by tissue inflammation of KCOTs with loss of defining criteria, resulting in misdiagnosis as an odontogenic jaw cyst. We discuss the possible merits of volumetric analysis when facing this particular diagnostic dilemma and for pathophysiological characterization of KCOTs. We included 114 patients, of whom 27 were histopathologically diagnosed with a KCOT and 87 with dentigerous (n = 41) and periapical cyst (n = 46)...
November 21, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29229314/an-atypical-odontogenic-myxoma
#20
L Benjelloun, N Cherradi, A Kessab, S Dghoughi
INTRODUCTION: Odontogenic myxoma is an uncommon tumor of the jaws, benign but locally invasive. It arises from the mesenchymal portion of the tooth germ. It has a variable non-specific clinical and radiological appearance, and may be confused with other lesions of the jaws. CASE REPORT: A patient aged 50 presented for a periodontal treatment. After routine retroalveolar x-rays, we noted a small limited radiolucency between the left mandibular canine and the left mandibular first premolar...
December 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
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