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https://www.readbyqxmd.com/read/29325264/-high-risk-factors-analysis-of-stillbirth
#1
Y Xiong, H X Xia, Y S Wang, X L Lin, T T Zhu, Y Zhao, X T Li
Objective: To explore the high risk factors of stillbirth. Methods: 176 cases of stillbirth were collected in the Obstetrics and Gynecology Hospital of Fudan University from January 1(st), 2010 to December 31(st), 2016. All cases were analyzed retrospectively, including general profile, high risk factors of stillbirth in different years and pregnancy periods. Results: (1) The incidence of stillbirth was 0.178%(176/98 785). Stillbirth occured mostly at 28-28(+6) gestational weeks (10.8%,19/176), and the second peak was 29-29(+6) weeks(10...
December 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29325263/-analysis-of-2-204-stillbirths-in-11-hospitals-of-guangdong-province
#2
L Yu, M Tang, X H Fan, H M Du, H Tang, P Chen, S L Xing, C H Su, D J Chen
Objective: To analyze the incidence and causes of stillbirth in 11 hospitals of Guangdong province, and to explore the appropriate interventions. Methods: Clinical data of stillbirth in 11 hospitals of Guangdong province were collected from January 2014 to December 2016. The gestational weeks, causes, maternal conditions and other factors were analyzed. Results: (1) From 2014 to 2016, 103 472 newborns were delivered in the 11 hospitals, and the number of stillbirth was 2 204, with the incidence of 2.13%. Among them, 0...
December 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29317119/noninvasive-ventilation-during-endoscopic-procedures-rationale-clinical-use-and-devices
#3
REVIEW
Marina Pieri, Giovanni Landoni, Luca Cabrini
Endoscopic procedures, such as transesophageal echocardiography, gastroscopy, and airway fibroscopy, routinely are performed in a heterogenous population of patients for diagnostic/interventional purposes (eg, transfemoral aortic valve replacement, airway fibroscopies, and intubation). Sedation frequently is administered to achieve an appropriate degree of patient compliance and procedure success. Patients with reduced respiratory reserve or those who are overly sedated, however, may develop hypoxia and respiratory failure during endoscopies, necessitating premature termination of the examination itself...
September 27, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29314219/pediatric-psoriasis-evolving-perspectives
#4
Lawrence F Eichenfield, Amy S Paller, Wynnis L Tom, Jeffrey Sugarman, Adelaide A Hebert, Sheila Fallon Friedlander, Elaine Siegfried, Nanette Silverberg, Kelly M Cordoro
BACKGROUND/OBJECTIVES: Childhood-onset psoriasis is a common skin disorder that has recently received increasing attention, particularly because of its significant medical, social, financial, and psychological burdens and its associated comorbidities. With limited data available and lack of standardized management guidelines for pediatric psoriasis, an expert panel desired to provide an updated critical overview and practical guidance for management of the affected population. METHODS: A panel of pediatric dermatologists with extensive experience in pediatric psoriasis defined and prioritized a core set of topics, performed an English-language literature review, prepared critical evaluations and presentations of topic areas, and carried out a consensus meeting and follow-up consensus manuscript...
January 4, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29313655/lung-cancer-management
#5
Timothy F Mott
Lung cancer management that is individualized for age, comorbidities, cancer type, cancer stage, and patient preference has long been a cornerstone of management. New to this realm of individualized management are the emerging biologic therapies, immunotherapies, and targeted therapies for non-small-cell lung cancer provided by advances in genetics and molecular medicine. These techniques have led to a new field of precision medicine based on the unique molecular characteristics of a specific patient and the specific cancer...
January 2018: FP Essentials
https://www.readbyqxmd.com/read/29312730/cost-effectiveness-analysis-of-sealant-impact-in-management-of-moderate-intraoperative-alveolar-air-leaks-during-video-assisted-thoracoscopic-surgery-lobectomy-a-multicentre-randomised-controlled-trial
#6
Francesco Zaraca, Maurizio Vaccarili, Gino Zaccagna, Pio Maniscalco, Giampiero Dolci, Birgit Feil, Reinhold Perkmann, Luca Bertolaccini, Roberto Crisci
Background: Intraoperative alveolar air leak (IOAAL) is one of most common complications after video-assisted thoracoscopic surgery (VATS) lobectomy. The study aimed to evaluate if, in moderate IOAAL, intraoperative polymeric biodegradable sealant (ProgelTM) reduced postoperative air leak (PAL) and consequently was cost-effective. Methods: Patients with moderate IOAAL were randomised in a multicentre trial to intraoperative use of a sealant (Sealant group) or standard management of air leaks (Control group)...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29309464/gorham-disease
#7
Kofi Agyeman, Juan Pretell-Mazzini, Ty Subhawong, Darcy A Kerr, Jean Jose
Gorham disease, a rare condition of unknown etiology, presents as skeletal lucency on radiographs, prompting the classic eponym of vanishing bone disease. Initial clinical presentation varies considerably but typically involves prolonged soreness in the affected region and, rarely, acute pathologic fracture. The nonspecific nature of complaints, lack of markers of systemic illness, and rarity of the disease contribute to delayed diagnosis. Several imaging studies (eg, plain radiographs, computed tomography, magnetic resonance imaging, nuclear studies) provide nonspecific findings, but frank cortical destruction and true "disappearance" of bone with extensive soft-tissue edema are evident...
November 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/29281187/review-on-hyperbaric-oxygen-treatment-in-femoral-head-necrosis
#8
Enrico Camporesi, Giuliano Vezzani, Vincenzo Zanon, Daniele Manelli, Garrett Enten, Silvia Quartesan, Gerardo Bosco
BACKGROUND: Femoral head necrosis (FHN) is a common invalidating disease with an unclear etiology and pathophysiology that affects middle-aged people. FHN may lead to joint collapse and require invasive treatments. Because of its clinical and socioeconomic significance, an early diagnosis, staging and appropriate treatment are required. Unfortunately, to date a unique algorithm for the treatment of FHN has not been defined. OBJECTIVE: In this report we summarize the Tenth European Consensus Conference on hyperbaric medicine (April 2016, France), during which experts from Europe revised the list of accepted indications for hyperbaric oxygen (HBO₂) treatment, including FHN...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29280599/surgical-counting-a-perioperative-nurse-s-perspective
#9
Vicky Warwick, Brigid Gillespie
The Australian College of Perioperative Nurses (ACORN) have developed a set of standards to guide clinical practice within the perioperative setting. The ACORN standard 'Management of accountable items used during surgery and procedures' (ACORN 2016) details a process for perioperative nurses to follow when undertaking a surgical count.
May 2017: Australian Nursing & Midwifery Journal
https://www.readbyqxmd.com/read/29274003/should-we-consider-integrated-approach-for-endometriosis-associated-infertility-as-gold-standard-management-rationale-and-results-from-a-large-cohort-analysis
#10
Vesna Šalamun, Ivan Verdenik, Antonio Simone Laganà, Eda Vrtačnik-Bokal
PURPOSE: To evaluate reproductive and maternal-fetal outcomes after integrated approach for endometriosis-associated infertility (EAI). METHODS: We retrospectively analyzed reproductive and maternal-fetal outcomes of 277 women affected by EAI, subdividing patients in two groups: in the first one (surgery group), we included all women who underwent laparoscopic surgery for EAI; in the second one (integrated group), we included women who failed to conceive spontaneously after surgery within 6-12 months and underwent in vitro fertilization and embryo transfer (IVF)...
December 22, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29260925/effective-management-strategies-for-patients-with-marginal-zone-lymphoma
#11
Cecilia B Rosand, Kelly Valla, Christopher R Flowers, Jean L Koff
Marginal zone lymphoma (MZL) is an uncommon indolent lymphoma classified into subtypes based on primary site of involvement: splenic, nodal and extranodal. MZLs' relative rarity has largely precluded adoption of a standard management strategy. Here, we provide an overview of the epidemiology, clinical behavior and therapeutic approaches for each subtype. Biologic insights into lymphomagenesis have identified B-cell receptor signaling as a rational therapeutic target. Recent clinical data suggest that novel agents targeting this pathway, including the Bruton's tyrosine kinase inhibitor, ibrutinib, show significant promise in treatment of relapsed MZL...
December 20, 2017: Future Oncology
https://www.readbyqxmd.com/read/29260358/abnormal-human-chorionic-gonadotropin-hcg-trends-after-transfer-of-multiple-embryos-resulting-in-viable-singleton-pregnancies
#12
Paula C Brady, Leslie V Farland, Stacey A Missmer, Catherine Racowsky, Janis H Fox
PURPOSE: The purpose of this study is to investigate whether abnormal hCG trends occur at a higher incidence among women conceiving singleton pregnancies following transfer of multiple (two or more) embryos (MET), as compared to those having a single embryo transfer (SET). METHODS: Retrospective cohort study was performed of women who conceived singleton pregnancies following fresh or frozen autologous IVF/ICSI cycles with day 3 or day 5 embryo transfers between 2007 and 2014 at a single academic medical center...
December 19, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29258550/the-impact-of-antiretroviral-therapy-on-iron-homeostasis-and-inflammation-markers-in-hiv-infected-patients-with-mild-anemia
#13
Eugenia Quiros-Roldan, Francesco Castelli, Paola Lanza, Chiara Pezzoli, Marika Vezzoli, Giorgio Biasiotto, Isabella Zanella
BACKGROUND: Anemia is frequent during HIV infection and is predictive of mortality. Although cART has demonstrated to reduce its prevalence, several patients still experience unresolved anemia. We aimed to characterize iron homeostasis and inflammation in HIV-infected individuals with mild anemia in relation to cART. METHODS: In this retrospective cohort study, HIV-infected patients with mild anemia, CD4+ cells > 200/mm3 at baseline, maintaining virological response for 12 months after cART starting were selected within the Standardized Management of Antiretroviral Therapy Cohort (MASTER) cohort...
December 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29243536/variation-in-pediatric-organ-donor-management-practices-among-us-organ-procurement-organizations
#14
Robert S Ream, Eric S Armbrecht
INTRODUCTION: Reports of actual pediatric organ donor management practice among US organ procurement organizations are sparse, and the use of standardized management guidelines is unknown. A recent consensus statement from the Society of Critical Care Medicine, the American College of Chest Physicians, and the Association of Organ Procurement Organizations offers guidelines for the management of the pediatric organ donor. RESEARCH QUESTION: To describe the use of guidelines and routine practices in the management of the pediatric organ donor with respect to hemodynamics, lung and ventilator management, fluid and electrolytes, hormonal replacement therapy, the use of blood products, thermoregulation, and prophylactic antibiotics...
January 1, 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29233756/paediatric-minimally-invasive-abdominal-and-urological-surgeries-current-trends-and-perioperative-management
#15
Myriam Bellon, Alia Skhiri, Florence Julien-Marsollier, Serge Malbezin, Diallo Thierno, Julie Hilly, Alaa ElGhoneimi, Arnaud Bonnard, Daphné Michelet, Souhayl Dahmani
Minimally invasive surgery during abdominal, thoracic and urological procedures has become the standard management of many surgical interventions in adults. Recent development of smaller devices has allowed the management of many paediatric surgeries using these minimally invasive techniques. However, the lack of knowledge of (a) adequate management of haemodynamic and respiratory alterations occurring during those procedures and (b) postoperative advantages of these techniques over open surgeries, still impairs their development...
December 9, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29230540/preventing-future-fractures-effectiveness-of-an-orthogeriatric-fracture-liaison-service-compared-to-an-outpatient-fracture-liaison-service-and-the-standard-management-in-patients-with-hip-fracture
#16
Antonio Naranjo, Sonia Fernández-Conde, Soledad Ojeda, Laura Torres-Hernández, Carolina Hernández-Carballo, Idoia Bernardos, Sinforiano Rodríguez, Pedro Laynez
An observational study was carried out in two hospitals in patients > 65 years admitted for hip fracture. At 6 months, 15% of patients in the hospital with orthogeriatric standard care and 75% in the hospital with fracture liaison service were receiving bisphosphonates. PURPOSE: Many patients with fractures are discharged without preventive therapy against further fractures. We sought to compare the effectiveness of an orthogeriatric fracture liaison service (FLS), outpatient FLS, and the standard care after hip fractures in prevention of future fractures...
December 11, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29199768/invasive-versus-non-invasive-ventilation-for-acute-respiratory-failure-in-neuromuscular-disease-and-chest-wall-disorders
#17
REVIEW
Fang Luo, Djillali Annane, David Orlikowski, Li He, Mi Yang, Muke Zhou, Guan J Liu
BACKGROUND: Acute respiratory failure is a common life-threatening complication of acute onset neuromuscular diseases, and may exacerbate chronic hypoventilation in patients with neuromuscular disease or chest wall disorders. Standard management includes oxygen supplementation, physiotherapy, cough assistance, and, whenever needed, antibiotics and intermittent positive pressure ventilation. Non-invasive mechanical ventilation (NIV) via nasal, buccal or full-face devices has become routine practice in many centres...
December 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29199724/survival-and-prognostic-factors-for-glioblastoma-multiforme-retrospective-single-institutional-study
#18
M Ghosh, S Shubham, K Mandal, V Trivedi, R Chauhan, S Naseera
INTRODUCTION: Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults. The standard management has been maximum surgical resection followed by adjuvant radiotherapy with concurrent chemotherapy followed by adjuvant chemotherapy. Although the survival rate of patients with GBM has improved with recent advancements in treatment, the prognosis remains generally poor. The median survival rates are in the range of 9-12 months and 2-year survival rates are in the range of 8%-12%...
January 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29189658/discharge-criteria-for-bronchiolitis-an-unmet-need
#19
Cristina Garcia-Mauriño, Melissa Moore-Clingenpeel, Rebecca Wallihan, Katalin Koranyi, Bavani Rajah, Tiffany Shirk, Maria Vegh, Octavio Ramilo, Asuncion Mejias
BACKGROUND: Admission criteria and standardized management strategies for bronchiolitis are addressed in several guidelines and have shown to be beneficial; however, guidance regarding discharge criteria is limited and widely variable. We assessed the impact on clinical outcomes of a discharge protocol for children < 2 years of age hospitalized with bronchiolitis in a tertiary care pediatric hospital. METHODS: In October 2013, a protocol to standardize the discharge of children with bronchiolitis was implemented in the infectious diseases (ID) ward, but not in other pediatric units caring for these children (non-ID)...
November 20, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29171661/a-randomised-controlled-trial-comparing-high-flow-nasal-oxygen-with-standard-management-for-conscious-sedation-during-bronchoscopy
#20
N Douglas, I Ng, F Nazeem, K Lee, P Mezzavia, R Krieser, D Steinfort, L Irving, R Segal
Traditional conscious sedation for endobronchial ultrasound procedures places patients at risk of desaturation, and high-flow nasal oxygen may reduce the risk. We designed a parallel-group randomised controlled trial of high-flow nasal oxygen at a flow rate of 30-70 l.min(-1) via nasal cannulae, compared with standard oxygen therapy at 10 l.min(-1) via a bite block in adults planned for conscious sedation for endobronchial ultrasound. The primary outcome was the proportion of patients experiencing desaturation (defined as SpO2 < 90%)...
November 24, 2017: Anaesthesia
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