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https://www.readbyqxmd.com/read/28225967/synchronous-melanomas-arising-within-nevus-spilus
#1
Maria Helena Toda Sanches de Brito, Cecília Silva Nunes de Moura Dionísio, Cândida Margarida Branco Martins Fernandes, Joana Cintia Monteiro Ferreira, Maria Joaninha Madalena de Palma Mendonça da Costa Rosa, Maria Manuela Antunes Pecegueiro da Silva Garcia
Nevus spilus is a melanocytic cutaneous lesion consisting of a light brown background macule with numerous superimposed darker maculopapular speckles. Melanoma arising from a nevus spilus is rare, with less than 40 cases reported to date. The absolute risk for malignant transformation is not well defined, lacking a standardized management approach. We report a new case of melanoma arising from nevus spilus, with the additional peculiarity of multifocality. We offer our recommendations for the management of the condition...
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28206933/use-of-antibiotic-impregnated-absorbable-beads-and-tissue-coverage-of-complex-wounds
#2
Terris L White, Alfred T Culliford, Martin Zomaya, Gary Freed, Christopher P Demas
The treatment of complex wounds is commonplace for plastic surgeons. Standard management is debridement of infected and devitalized tissue and systemic antibiotic therapy. In cases where vital structures are exposed within the wound, coverage is obtained with the use of vascularized tissue using both muscle and fasciocutaneous flaps. The use of nondissolving polymethylmethacrylate and absorbable antibiotic-impregnated beads has been shown to deliver high concentrations of antibiotics with low systemic levels of the same antibiotic...
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28183347/application-of-incident-command-structure-to-clinical-trial-management-in-the-academic-setting-principles-and-lessons-learned
#3
Penny S Reynolds, Mary J Michael, Bruce D Spiess
BACKGROUND: Clinical trial success depends on appropriate management, but practical guidance to trial organisation and planning is lacking. The Incident Command System (ICS) is the 'gold standard' management system developed for managing diverse operations in major incident and public health arenas. It enables effective and flexible management through integration of personnel, procedures, resources, and communications within a common hierarchical organisational structure. Conventional ICS organisation consists of five function modules: Command, Planning, Operations, Logistics, and Finance/Administration...
February 9, 2017: Trials
https://www.readbyqxmd.com/read/28183146/prenatal-and-postnatal-management-of-gastroschisis-in-german-speaking-countries-is-there-a-standardized-management
#4
Katharina Schib, Marc Schumacher, Martin Meuli, Sasha Tharakan, Ulrike Subotic
Introduction Evidence-based guidelines or protocols regarding the perinatal management of babies born with gastroschisis are lacking. The aim of this work is to evaluate the different current treatment modalities for newborns with gastroschisis during the perinatal period in the German-speaking countries Germany, Austria, and Switzerland. These data could serve as a starting point for the development of a multicenter randomized controlled trial. Materials and Methods A questionnaire was developed with 30 questions divided into five sections: (1) prenatal diagnosis, (2) fetal therapy, (3) mode and timing of delivery, (4) operative management, and (5) postoperative management...
February 9, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28179438/management-of-continuous-positive-airway-pressure-treatment-compliance-using-telemonitoring-in-obstructive-sleep-apnoea
#5
Cecilia Turino, Jordi de Batlle, Holger Woehrle, Ana Mayoral, Anabel Lourdes Castro-Grattoni, Sílvia Gómez, Mireia Dalmases, Manuel Sánchez-de-la-Torre, Ferran Barbé
Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnoea (OSA), but treatment compliance is often unsatisfactory. This study investigated the efficacy and cost-effectiveness of telemonitoring for improving CPAP compliance.100 newly diagnosed OSA patients requiring CPAP (apnoea-hypopnoea index >15 events·h(-1)) were randomised to standard management or a telemonitoring programme that collected daily information about compliance, air leaks and residual respiratory events, and initiated patient contact to resolve issues...
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28177209/the-association-between-the-regular-use-of-early-term-labor-induction-and-improved-birth-outcomes-new-evidence-from-an-italian-hospital
#6
Gregorio Del Boca, Anna Biffi, Roberto Zagni, Gianluca R Damiani, James M Nicholson
OBJECTIVE: Associations have been recently reported between the frequent use of early-term preventive labor induction and improvements in multiple parameters of birth health. We sought to replicate these findings in an Italian hospital. STUDY DESIGN: The outcomes of 120 consecutively delivered women who were exposed to the alternative method of care were compared to the outcomes of 159 women who received standard management. The primary and secondary outcomes were group cesarean delivery rate and group adverse outcome index score...
February 8, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28175931/determining-patient-preferences-for-indeterminate-thyroid-nodules-observation-surgery-or-molecular-tests
#7
Daniel Joonil Lee, Jason J Xu, Dale H Brown, Ralph W Gilbert, Patrick J Gullane, Jonathan C Irish, Lorne E Rotstein, David P Goldstein, John R de Almeida
BACKGROUND: Gene-expression classifiers (GEC) and genetic mutation panels (GMP) have been shown to improve preoperative diagnostic evaluations of indeterminate thyroid nodules. Despite the improvement, uncertainty regarding the proper management exists. Patient preferences may better inform the management of these indeterminate thyroid nodules. METHODS: Hypothetical scenarios were administered to two groups of patients: those with previous FNA-confirmed indeterminate thyroid nodules (Group A, n = 50) and those presenting to a general otolaryngology clinic for other reasons (Group B, n = 50)...
February 7, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28165546/highly-standardized-cranberry-extract-supplementation-anthocran%C3%A2-as-prophylaxis-in-young-healthy-subjects-with-recurrent-urinary-tract-infections
#8
A Ledda, G Belcaro, M Dugall, A Riva, S Togni, R Eggenhoffner, L Giacomelli
OBJECTIVE: Several studies have investigated the role of cranberry extract in the prevention of recurrent urinary tract infections (UTIs), on different selected subpopulations at increased risk of UTI. In this registry, we tested the prophylactic effects of an oral supplementation containing a highly standardized cranberry extract (Anthocran®) in young subjects with a previous history of recurrent UTIs, over a 2-months follow-up. PATIENTS AND METHODS: 36 otherwise healthy subjects in juvenile age (between 12 and 18 years of age) suffering by recurrent UTIs were enrolled...
January 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28161918/bowled-over-by-cricket-impact-of-tape-ball-injuries-on-the-eyes
#9
Salman Naveed Sadiq, Azam Ali, Bushra Usmani, Khabir Ahmad
PURPOSE: The aim of this study was to describe the type and severity of tape-ball cricket-related eye injuries seen at a tertiary care hospital. DESIGN: A descriptive case series. METHODS: This study included all cases of tape-ball cricket-related eye injuries presenting to the Section of Ophthalmology, Aga Khan University Hospital, Karachi, from January 2014 to January 2015. RESULTS: A total of 20 patients with tape-ball cricket-related eye injuries were treated during this period...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28153344/frequency-of-pocket-hematoma-in-patients-receiving-vitamin-k-antagonist-and-antiplatelet-therapy-at-the-time-of-pacemaker-or-cardioverter-defibrillator-implantation-from-the-pocket-study
#10
Michele Malagù, Filippo Trevisan, Antonella Scalone, Lina Marcantoni, Giuseppe Sammarco, Matteo Bertini
In patients undergoing cardiac device implantation, anticoagulant and antiplatelet therapy are associated with an increased risk of pocket hematoma. In case of vitamin K antagonist therapy, a strategy of continued warfarin with no heparin bridge showed a reduction of pocket hematoma. Evidence regarding antiplatelet therapy management is limited. This is a single-center observational study which reflects our systematic approach to the problem. In 2012, we proposed an improved management protocol for anticoagulant and antiplatelet therapy (no-bridge protocol) based on individual thromboembolic risk stratification, noninterruption of oral anticoagulation, no bridge with heparin and elastic adherence compression bandage...
January 6, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28148230/specialist-antenatal-clinics-for-women-at-high-risk-of-preterm-birth-a-systematic-review-of-qualitative-and-quantitative-research
#11
Reem Malouf, Maggie Redshaw
BACKGROUND: Preterm birth (PTB) is the leading cause of perinatal morbidity and mortality. Women with previous prenatal loss are at higher risk of preterm birth. A specialist antenatal clinic is considered as one approach to improve maternity and pregnancy outcomes. METHODS: A systematic review of quantitative, qualitative and mixed method studies conducted on women at high risk of preterm birth (PTB). The review primary outcomes were to report on the specialist antenatal clinics effect in preventing or reducing preterm birth, perinatal mortality and morbidity and women's perceptions and experiences of a specialist clinic whether compared or not compared with standard antenatal care...
February 2, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28134501/the-current-and-future-role-of-biomarkers-in-type-2-cytokine-mediated-asthma-management
#12
REVIEW
I D Pavord, S Afzalnia, A Menzies-Gow, L G Heaney
Assessment and management of asthma is complicated by the heterogeneous pathophysiological mechanisms that underlie its clinical presentation, which are not necessarily reflected in standardized management paradigms and which necessitate an individualized approach to treatment. This is particularly important with the emerging availability of a variety of targeted forms of therapy that may only be appropriate for use in particular patient subgroups. The identification of biomarkers can potentially aid diagnosis and inform prognosis, help guide treatment decisions and allow clinicians to predict and monitor response to treatment...
February 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28127861/mass-rearing-and-augmentative-biological-control-evaluation-of-rhynocoris-fuscipes-hemiptera-reduviidae-against-multiple-pests-of-cotton
#13
Majesh Thomson, Kitherian Sahayaraj, Vivek Kumar, Pasco B Avery, Cindy L McKenzie, Lance S Osborne
BACKGROUND: Rhynocoris fuscipes (Fab.) (Hemiptera: Reduviidae) is a generalist predator of cotton pests and is commonly found inhabiting cotton growing regions in southern India. With the goal to integrate this predator in standard management practices used against cotton pests on a commercial scale, 1) we developed a protocol for adult group rearing of this predator inside Micro Environmental Cages (MECs), and 2) evaluated the biocontrol potential of mass produced predators against cotton pests under potted and field conditions...
January 27, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28109602/strategies-to-gain-body-condition-score-in-pasture-based-dairy-cows-during-late-lactation-and-the-far-off-nonlactating-period-and-their-interaction-with-close-up-dry-matter-intake
#14
J R Roche, A Heiser, M D Mitchell, M A Crookenden, C G Walker, J K Kay, M Vailati Riboni, J J Loor, S Meier
In pasture-based systems, cows are generally thinner at the end of lactation than cows fed total mixed rations and, as a result, over-feeding of metabolizable energy (ME) during the far-off nonlactating period is a standard management policy to achieve optimum calving body condition score (BCS). An alternative would be to manage cows to gain BCS through late lactation, such that cows ended lactation close to optimum calving BCS and maintenance of BCS through to calving. We sought to quantify the effect of moderate or excessive ME intakes during the far-off nonlactating period in cows that had been managed to gain or maintain BCS through late lactation and whether the far-off management strategy interacted with close-up level of feeding...
March 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28109315/evaluation-of-surgical-treatment-for-incidental-gallbladder-carcinoma-diagnosed-during-or-after-laparoscopic-cholecystectomy-single-center-results
#15
Masashi Utsumi, Hideki Aoki, Tomoyoshi Kunitomo, Yutaka Mushiake, Isao Yasuhara, Takashi Arata, Koh Katsuda, Kohji Tanakaya, Hitoshi Takeuchi
BACKGROUND: Laparoscopic cholecystectomy (LC) is the accepted standard management for benign gallbladder disease. LC rarely results in a diagnosis of incidental gallbladder carcinoma (IGBC). The aim of our study was to report our experience with IGBC diagnosed during or following LC. METHODS: Between January 2008 and January 2015, 352 patients underwent LC at Iwakuni Clinical Center. Among these patients, 8 (2.3%) were diagnosed with IGBC. We evaluated their characteristics, surgical related variables, histopathological findings and surgical outcomes...
January 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28087903/-interpretation-of-2016-asthma-management-and-prevention-guideline
#16
Wen Hua, Huaqiong Huang, Huahao Shen
The revision in 2016 asthma management and prevention guideline includes both the diagnosis of asthma and the control-based asthma management. It points out that asthma is a heterogeneous disease, and the diagnosis of asthma should be based on the characteristic pattern of symptoms and evidence of variable airflow limitation, emphasizing the diagnosis of atypical asthma. Besides, the epidemiology of asthma, assessment of asthma, management severe asthma, special type of asthma and asthma in special populations have been added in this version...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28087308/myocardial-inotropic-reserve-an-old-twist-that-constitutes-a-reliable-index-in-the-modern-era-of-heart-failure
#17
REVIEW
Fragkiskos Parthenakis, Spyridon Maragkoudakis, Maria Marketou, Alexandros Patrianakos, Evaggelos Zacharis, Panos Vardas
Current national and international guidelines, including those of the European Society of Cardiology, recognize that the assessment of prognosis should be a part of the standard management for patients with chronic heart failure (CHF). However, these same guidelines recognize the inherent difficulty of this process. A variety of factors contribute to this difficulty, including the varying etiology, frequent co-morbidity and, perhaps most importantly, huge inter-individual variability in the disease progression and outcome...
November 22, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28065727/neovaginal-prolapse-treated-with-sacrospinous-ligament-suspension-a-case-report-and-review-of-the-literature
#18
Zhimin Hao, Sufen Yang
Neovaginal prolapse (NP) is a rare event and limited cases have been reported in the literature. After surgical management, NP recurs in some cases, posing a great challenge to gynecologists. Fixing neovagina to sacrospinous ligament would appear to be a good option for preventing the recurrence of NP, but too few cases have been reported to establish this technique as the standard management of NP. Herein, we present a case of severe mucosal prolapse of sigmoid neovagina and conduct a review of the literature regarding the etiology, prevention, and management of NP...
January 5, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28051248/movardol%C3%A2-n-acetylglucosamine-boswellia-serrata-ginger-supplementation-in-the-management-of-knee-osteoarthritis-preliminary-results-from-a-6-month-registry-study
#19
G Bolognesi, G Belcaro, B Feragalli, U Cornelli, R Cotellese, S Hu, M Dugall
OBJECTIVE: Knee Osteoarthritis (OA) is a chronic disease caused by the deterioration of cartilage in joints, which results in activation of the inflammatory response, pain, and impaired movement. Complementary therapies, particularly supplementation, in the management of moderate/severe knee OA have been gaining attention. This registry study aimed at evaluating the synergistic effect of Movardol®, a supplementation containing active ingredients with recognized anti-inflammatory activities on symptoms and levels of circulating biomarkers of knee OA...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28051247/supplementation-with-high-titer-cranberry-extract-anthocran%C3%A2-for-the-prevention-of-recurrent-urinary-tract-infections-in-elderly-men-suffering-from-moderate-prostatic-hyperplasia-a-pilot-study
#20
A Ledda, G Belcaro, M Dugall, B Feragalli, A Riva, S Togni, L Giacomelli
OBJECTIVE: Recently, cranberry extracts have been tested as a nutritional supplementation in the prevention of lower urinary tract symptoms (LUTS) as well as recurrent urinary tract infections (UTIs) in subjects at risk, with mixed results. However, evidence of efficacy should be considered only for well-characterized and standardized products in a more selected study population. Moreover, the efficacy of these interventions in elderly must be further investigated. The aim of this pilot, registry study was to evaluate the prophylactic effects of an oral supplementation containing a highly concentrated and standardized cranberry extract reproducing the natural total profile of cranberry fruits, in elderly men with benign prostatic hyperplasia (BPH), suffering from recurrent UTIs, over a 2-months follow-up...
December 2016: European Review for Medical and Pharmacological Sciences
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