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Streptococcus pnemoniae

Salman Khan, Singh Priti, Sachan Ankit
BACKGROUND: Lower respiratory tract infections (LTRIs) are among the most common infectious diseases with potential life-threatening complications. METHODS: The study consisted of 426 patients with suspected LTRIs from mid and far western region of Nepal between September 2011 and July 2014. The specimens were collected and processed according to the standard microbiological methods at the Central Laboratory of Microbiology of Nepalgunj Medical College, Nepal. RESULTS: Among the isolated Gram-positive organisms, Streptococcus pneumonia (n = 30, 51...
2015: Iranian Biomedical Journal
R Mazumder, T Mendiratta, S C Mondal, A Mazumder
The methanolic extract of the leaf-stalk of curcuma longa LINN, was tested for its minimum Inhibitor concentration (MIC) against Gram positive-staphylococcus aureus, Bacillus pumilus, Bacillus subtilis, klebsiella pnemoniae, bacillus cereus, streptococcus pneumoniae, Lactobacillus arabinosus and gram negative E.coli, shigella dysenteriae, shigella sonnei, shigella boydii, salmonella typhimurium, proteus mirabilis, and Vibrio cholerae strains, further, the ones of inhibition produced by the crude extract against four selected bacterial strains were measured and compared with those produced by the standard antibiotic ciprofloxacin against the same bacterial strains...
July 2000: Ancient Science of Life
Chaitanya Mulakayala, Babajan Nawaz Banaganapalli, C M Anuradha, Suresh Kumar Chitta
Streptococcus pneumonia is the common cause of sepsis and meningitis. Emergence of multiple antibiotic resistant strains in the community-acquired bacterium is catastrophic. Glucose kinase (GLK) is a regulatory enzyme capable of adding phosphate group to glucose in the first step of streptomycin biosynthesis. The activity of glucose kinase was regulated by the Carbon Catabolite Repression (CCR) system. Therefore, it is important to establish the structure-function relation of GLK in S. pneumoniae. However, a solved structure for S...
2009: Bioinformation
Kiwao Watanabe, Dang Duc Anh, Phan Le Thanh Huong, Nguyen Thu Nguyet, Nguyen Thu Hien Anh, Ngo Thi Thi, Nguyen Tien Dung, Doan Mai Phuong, Olivia S Rusizoka, Tsuyoshi Nagatake, Hiroshi Watanabe, Kazunori Oishi
BACKGROUND: Acute lower respiratory infections (ALRI), primarily pneumonia, are the leading cause of death in children under 5 years of age. Most of these deaths occur in Africa and southeast Asia. Increasing rates of drug resistance in pneumococcal strains emphasize the necessity of prevention of pneumococcal vaccines. The aim of the present study was to determine the frequency of drug resistance and the distribution of serotype of pneumococcal strains isolated from pediatric patients with ALRI in Vietnam...
August 2008: Pediatrics International: Official Journal of the Japan Pediatric Society
D Banerjee, D Honeybourne
Chronic obstructive pulmonary disease is a disease state characterized by the presence of airflow obstruction due to chronic bronchitis and/or emphysema. The airflow obstruction is generally progressive. In the past asthma was often confused with chronic obstructive pulmonary disease but as the cellular inflammatory mechanisms are quite different to chronic bronchitis and emphysema it is prudent to separate this condition of airway hyper-responsiveness. Exacerbation of chronic obstructive pulmonary disease is a considerable burden on health service resources in terms of morbidity and mortality...
December 1999: Current Opinion in Infectious Diseases
Reena Jain, Urmil Tuteja, Harsh Vardhan Batra
The 3 murine monoclonal antibodies, Yps1, Yps2 and Yps3 reactive to Y. pseudotuberculosis can be stabilized and all were found to be of IgG type. Monoclonal antibody, Yps1, recognized a glycoprotein antigen of the organism with reactivity at the 55-75 kDa region, while Yps2 and Yps3 recognized protein antigens of Y. pseudotuberculosis 65 kDa and 26-28 kDa molecular weight regions, respectively. The specificity of monoclonal antibodies was tested using dot ELISA and Western blotting with whole cell organisms or whole cell sonicated soluble antigens of different Yersinia species, Salmonella typhi, Klebsiella pnemoniae, Streptococcus abortus-equi and Escherichia coli...
December 2003: Southeast Asian Journal of Tropical Medicine and Public Health
K F Fashae, F T Ogunsola, O M Salawu, A O Dada, O Popoola
Streptococcus pneumoniae is an important aetiological agent of infections in children worldwide. The isolation rate of the bacteria has been strikingly low in the recent past in Nigeria. In a study of 1000 blood samples from patients, out of which 642 were from children in Ibadan between May 1999 and December 2000, 14 isolates of Streptococcus pneumoniae were obtained (a prevalence rate of 1.4%). All the isolates were from children and clustered between 13th September and 22nd October 1999, period of 40 days and thereafter no more organisms were isolated...
June 2002: African Journal of Medicine and Medical Sciences
Sung-Hee Um, Dong-Kwon Rhee, Suhkneung Pyo
Capsular polysaccharide type 2 (PS) from Streptococcus pnemoniae induced the secretory and cellular macrophage response. However, the exact mechanism by which PS regulates the macrophage functions remains unclear. In this study, we examined signal molecules which may participate in PS-elicited responses by macrophages. Our data demonstrated that tumoricidal activation of macrophages induced by PS was inhibited by either protein kinase C (PKC) inhibitor, H7 or protein tyrosine kinase (PTK) inhibitor, genistein...
January 2002: International Immunopharmacology
S H Um, E W Son, B O Kim, E Y Moon, D K Rhee, S Pyo
In this study we examined the ability of capsular polysaccharide type 2 (PS) from Streptococcus pnemoniae to induce secretory and cellular responses in peritoneal macrophages. Tumour cytotoxicity induced by preincubation with PS was demonstrated to be concentration-dependent. PS-induced tumouricidal activity was partially abrogated by anti-tumour necrosis factor (TNF)-alpha and inhibitor of nitric oxide, whereas anti-interferon (IFN)-alpha/beta antibody and the scavengers of reactive oxygen intermediates had no effect...
July 2000: Scandinavian Journal of Immunology
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