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https://www.readbyqxmd.com/read/28404133/effect-on-hbs-antigen-clearance-of-addition-of-pegylated-interferon-alfa-2a-to-nucleos-t-ide-analogue-therapy-versus-nucleos-t-ide-analogue-therapy-alone-in-patients-with-hbe-antigen-negative-chronic-hepatitis-b-and-sustained-undetectable-plasma-hepatitis-b
#1
Marc Bourlière, Pascaline Rabiega, Nathalie Ganne-Carrie, Lawrence Serfaty, Patrick Marcellin, Yoann Barthe, Dominique Thabut, Dominique Guyader, Christophe Hezode, Magali Picon, Xavier Causse, Vincent Leroy, Jean Pierre Bronowicki, Patrizia Carrieri, Ghassan Riachi, Isabelle Rosa, Pierre Attali, Jean Michel Molina, Yannick Bacq, Albert Tran, Jean Didier Grangé, Fabien Zoulim, Hélène Fontaine, Laurent Alric, Inga Bertucci, Magali Bouvier-Alias, Fabrice Carrat
BACKGROUND: Findings from uncontrolled studies suggest that addition of pegylated interferon in patients with HBe antigen (HBeAg)-negative chronic hepatitis B receiving nucleos(t)ide analogues with undetectable plasma hepatitis B virus (HBV) DNA might increase HBs antigen (HBsAg) clearance. We aimed to assess this strategy. METHODS: In this randomised, controlled, open-label trial, we enrolled patients aged 18-75 years with HBeAg-negative chronic hepatitis B and documented negative HBV DNA while on stable nucleos(t)ide analogue regimens for at least 1 year from 30 hepatology tertiary care wards in France...
March 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28328794/hcv-drives-increased-type-i-ifn-associated-impairments-associated-to-fibrosis-severity-in-art-treated-hiv-1-hcv-coinfected-individuals
#2
Morgane Griesbeck, Marc-Antoine Valantin, Karine Lacombe, Assia Samri-Hassimi, Julie Bottero, Catherine Blanc, Zineb Sbihi, Rima Zoorob, Christine Katlama, Marguerite Guiguet, Marcus Altfeld, Brigitte Autran
BACKGROUND: Viral coinfections might contribute to the increased immune activation and inflammation that persist in ART-treated HIV-1 patients. We investigated whether the HCV co-infection contributes to such alterations by impairing the pDC IFNα/TLR7 pathway in a highly homogeneous group of ART-treated HIV-1-HCV co-infected patients. METHODS: Twenty nine HIV-1-infected patients with fully suppressive ART were included, fifteen of whom being HCV co-infected with mild to moderate fibrosis and matched for their HIV-1 disease, and thirteen control healthy donors...
March 21, 2017: AIDS
https://www.readbyqxmd.com/read/28124308/preoperative-progressive-pneumoperitoneum-and-botulinum-toxin-type-a-in-patients-with-large-incisional-hernia
#3
J Bueno-Lledó, A Torregrosa, N Ballester, O Carreño, F Carbonell, P G Pastor, J Pamies, V Cortés, S Bonafé, J Iserte
PURPOSE: Combination of preoperative progressive pneumoperitoneum (PPP) and botulinum toxin type A (BT) has not been previously reported in the management of large incisional hernia (LIH). METHODS: Observational study of 45 consecutive patients with LIH between June 2010 and July 2014. The diameters of the hernia sac, the volumes of the incisional hernia (VIH) and the abdominal cavity (VAC), and the VIH/VAC ratio were measured before and after PPP and BT using abdominal CT scan data...
April 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28109341/leadership-and-innovation-listening-to-and-learning-from-young-people-in-burundi
#4
Cédric Nininahazwe, Jacquelyne Alesi, Georgina Caswell, Musah Lumumba, Julie Mellin, Nicholas-Monalisa Ndayizeye, Luisa Orza, Michaela Rahimi, Nienke Westerhof
This commentary describes young people's leadership from the perspective of a youth-led organization in the Link Up project in Burundi, Réseau National des Jeunes vivant avec le VIH. It describes processes that enable young people to guide, influence, deliver, and improve health service provision; the challenges faced by Réseau National des Jeunes vivant avec le VIH and how they are addressing these challenges.
February 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28063568/lignes-directrices-canadiennes-en-mati%C3%A3-re-de-planification-de-la-grossesse-en-pr%C3%A3-sence-du-vih
#5
Mona R Loutfy, Shari Margolese, Deborah M Money, Mathias Gysler, Scot Hamilton, Mark H Yudin
No abstract text is available yet for this article.
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063557/lignes-directrices-pour-ce-qui-est-des-soins-%C3%A3-offrir-aux-femmes-enceintes-qui-vivent-avec-le-vih-et-des-interventions-visant-%C3%A3-att%C3%A3-nuer-la-transmission-p%C3%A3-rinatale-r%C3%A3-sum%C3%A3-directif
#6
Deborah Money, Karen Tulloch, Isabelle Boucoiran, Sheila Caddy
No abstract text is available yet for this article.
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28062305/involvement-of-second-messengers-in-the-signaling-pathway-of-vitellogenesis-inhibiting-hormone-and-their-effects-on-vitellogenin-mrna-expression-in-the-whiteleg-shrimp-litopenaeus-vannamei
#7
Sun-Hye Bae, Tomoyuki Okutsu, Naoaki Tsutsui, Bong Jung Kang, Hsiang-Yin Chen, Marcy N Wilder
We incubated fragments of Litopenaeus vannamei ovary to investigate second messengers involved in the regulation of vitellogenin (vg) mRNA levels. The use of 100nM recombinant vitellogenesis-inhibiting hormone (VIH) (corresponding to recombinant L. vannamei sinus gland peptide-G: rLiv-SGP-G) significantly reduced vg mRNA expression in sub-adults after 8h incubation to less than 20% of the control. The concentration of intracellular cyclic guanosine monophosphate (cGMP) increased 3.2-fold relative to the control after 2h incubation with rLiv-SGP-G...
January 3, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/27878224/potential-drug-interactions-in-patients-given-antiretroviral-therapy
#8
Wendel Mombaque Dos Santos, Silvia Regina Secoli, Stela Maris de Mello Padoin
Objective: to investigate potential drug-drug interactions (PDDI) in patients with HIV infection on antiretroviral therapy. Methods: a cross-sectional study was conducted on 161 adults with HIV infection. Clinical, socio demographic, and antiretroviral treatment data were collected. To analyze the potential drug interactions, we used the software Micromedex(r). Statistical analysis was performed by binary logistic regression, with a p-value of ≤0.05 considered statistically significant...
November 21, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27743227/cancer%C3%A2-survivorship-defining-the-incidence-of-incisional-hernia-after-resection-for-intra-abdominal-malignancy
#9
Rebeccah B Baucom, Jenny Ousley, Gloria B Beveridge, Sharon E Phillips, Richard A Pierce, Michael D Holzman, Kenneth W Sharp, William H Nealon, Benjamin K Poulose
BACKGROUND: Cancer survivorship focuses largely on improving quality of life. We aimed to determine the rate of ventral incisional hernia (VIH) formation after cancer resection, with implications for survivorship. METHODS: Patients without prior VIH who underwent abdominal malignancy resections at a tertiary center were followed up to 2 years. Patients with a viewable preoperative computed tomography (CT) scan and CT within 2 years postoperatively were included...
December 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27695297/self-perception-of-knowledge-and-adherence-reflecting-the-effectiveness-of-antiretroviral-therapy
#10
Carolina Dagli-Hernandez, Rosa Camila Lucchetta, Tales Rubens de Nadai, José Carlos Fernandez Galduróz, Patricia de Carvalho Mastroianni
OBJECTIVES: To evaluate which indirect method for assessing adherence best reflects highly active antiretroviral therapy (HAART) effectiveness and the factors related to adherence. METHOD: This descriptive, cross-sectional study was performed in 2012 at a reference center of the state of São Paulo. Self-report (simplified medication adherence questionnaire [SMAQ]) and drug refill parameters were compared to the viral load (clinical parameter of the effectiveness of pharmacotherapy [EP]) to evaluate the EP...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27627120/tuberculosis-control-in-people-living-with-hiv-aids
#11
Gabriela Tavares Magnabosco, Lívia Maria Lopes, Rubia Laine de Paula Andrade, Maria Eugênia Firmino Brunello, Aline Aparecida Monroe, Tereza Cristina Scatena Villa
OBJECTIVE: to analyze the offering of health actions and services for the control of tuberculosis for people living with HIV/AIDS being followed up in the Specialized Care Services for HIV/AIDS in Ribeirão Preto, SP, Brazil. METHOD: quantitative, exploratory survey study. Participated 253 people living with HIV/AIDS followed up by this service, considering as inclusion criteria: individuals older than 18 years living in the city and not inmates. Data collection was conducted from January 2012 to May 2013 through interviews with the support of a specific instrument...
September 9, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27625202/prevalence-of-and-factors-associated-with-depression-among-people-living-with-hiv-in-france
#12
P Feuillet, F Lert, L Tron, C Aubriere, B Spire, R Dray-Spira
OBJECTIVES: Depression is common among people living with HIV (PLWHIV) and is associated with poorer therapeutic outcomes and risky behaviours. We sought to estimate the prevalence of major depressive episode (MDE) across PLWHIV groups, to compare this with its prevalence in the general population and to assess factors associated with it. METHODS: We used data from the Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS)-Vespa2 study, a national study on a representative sample of PLWHIV conducted in France in 2011...
September 14, 2016: HIV Medicine
https://www.readbyqxmd.com/read/27617525/criptococosis-cut%C3%A3-nea-primaria-en-paciente-inmunocompetente
#13
Igor Vázquez-Osorio, Sara García-Rodiño, Marta Rodríguez-Rodríguez, Javier Labandeira, José Manuel Suárez-Peñaranda, MDolores Sánchez-Aguilar, Hugo Vázquez-Veiga
La criptococosis cutánea es una micosis propia de pacientes inmunodeprimidos, sobre todo aquellos con infección por el virusde la inmunodeficiencia humana (VIH). Sin embargo, existen casos infrecuentes de criptococosis cutánea en pacientes inmunocompetentes, que suelen simular otras dermatosis, lo que retrasa su diagnóstico y tratamiento. Presentamos el caso de un varón pluripatológico de 79 años, con úlceras dolorosas en dorso de mano derecha que no respondían a tratamientos tópicos. A través del estudio histopatológico y micológico se alcanzó el diagnóstico de criptococosis cutánea primaria, lográndose la remisión de las lesiones tras 6 meses de tratamiento con fluconazol...
May 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27598375/sexual-violence-as-a-limiting-factor-on-the-perception-and-management-of-the-risk-of-hiv-in-women-married-to-migrants
#14
Yesica Yolanda Rangel Flores
OBJECTIVE: to analyze the influence of sexual violence on the perception and management of the risk of HIV in women married to migrants. METHODS: study with an ethnographic approach carried out in urban and rural communities. Data were obtained by methodological triangulation, with participant and non-participant observation, as well as interviews. The informants were 21 women married to international migrants. The interviews were transcribed and discourse analysis was applied to them...
September 1, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27476253/-genital-tuberculosis-atypical-manifestation-in-the-pregnancy-case-report
#15
A Franco-Sansaloni, J Vizcaíno-Torres, J Gaona-Morales, D Estellés-Morant, J Antonio-Serrano
BACKGROUND: In the last years has been an increase in cases of tu- berculosis, representing a global health problem that is also reflected in an increased of cases in pregnant population. Especially in developed countries has been observed a direct relation with VIH patients,and groups of immigrants from countries where the infection is endemic. Tuberculous disease during pregnancy presents good outcome if it is diagnosed and treated properly. CASE REPORT: We present the case of a romanian patient with uncon- trolled 23 weeks gestation that enters with the suspicion of chorioam- nionitis and after late septic miscarriage and clinical sepsis criteria, leaks out of the hospital reentering with signs of neurologic involvement and pelviperitonitis as a result of genital tuberculous...
May 2016: Ginecología y Obstetricia de México
https://www.readbyqxmd.com/read/27475942/health-services-use-and-hiv-prevalence-among-migrant-and-national-female-sex-workers-in-portugal-are-we-providing-the-services-needed
#16
Sónia Dias, Ana Gama, Marta Pingarilho, Daniel Simões, Luís Mendão
This cross-sectional bio-behavioral survey conducted with 853 female sex workers (FSW) aimed to examine differences in use of HIV health services, testing and prevalence among migrant and national FSW. A quarter of undocumented FSW had never used National Health Service (NHS) and 15 % never tested for HIV, significantly more than nationals (p < 0.001 and p = 0.024, respectively). HIV infection was self-reported by 11.9 % of nationals, 1.8 % of documented and 0.8 % of undocumented migrants (p < 0...
July 30, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27439457/fingerprick-versus-oral-swab-acceptability-of-blood-based-testing-increases-if-other-stis-can-be-detected
#17
Ivan Balán, Timothy Frasca, Mobolaji Ibitoye, Curtis Dolezal, Alex Carballo-Diéguez
Self-testing has untapped potential as a strategy to improve access to HIV testing and to increase testing frequency. User acceptability of self-administered oral swab HIV tests is consistently high in both hypothetical and actual-use studies. We explored preferences for oral versus fingerprick HIV self-tests among men who have sex with men with a high risk profile. Participants indicated greater likelihood of using an oral swab over a blood-based test, notwithstanding lower price or quicker results from the latter...
February 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/27332416/vih-tavie
#18
Geneviève Rouleau, Lauralie Richard, José Côté
The use of information and communication technologies for designing web-based nursing interventions is growing exponentially. Despite the interest devoted to such approaches, little is known about their foundational principles and the way they translate into virtual nursing practice to generate meaningful engagement with patients. VIH-TAVIE<sup>TM</sup> is a virtual nursing intervention aiming to empower people living with HIV to help them in managing their antiretroviral therapy. Here we present VIH-TAVIE<sup>TM</sup> relational model of engagement - its core components informed by interview data with patients and a virtual nurse: building a virtual presence founded on caring relational principles and values; creating a caring environment where patients feel safe, supported and respected; stimulating patients' engagement by offering supportive and tailored messages; transposing nursing communication skills into a virtual practice to build trust and reciprocal relationships...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27257222/mujeres-que-consumen-sustancias-y-su-vulnerabilidad-frente-al-vih-en-santiago-de-chile-women-who-consume-substances-and-their-vulnerability-to-hiv-in-santiago-of-chile
#19
Lisette P Irarrázabal, Lilian Ferrer, Natalia Villegas, Sebastián Sanhueza, Yerko Molina, Rosina Cianelli
INTRODUCTION: Women represent 15% of the people living with HIV in Chile. Risk behaviors for HIV are: multiple partners, unsafe sex, and exchange of sex for drugs/money. METHODOLOGY: A correlational design was used. A sample of 203 women who were sexually active and consumed substances within the last 3-months were selected for this study. RESULTS: The average age of the participants was 32.4 years (SD = 9.2) and 68.1% were housewives. The substance most commonly used was alcohol (95...
June 2016: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/27257190/factores-que-influencian-la-adquisici%C3%A3-n-de-infecciones-de-transmisi%C3%A3-n-sexual-y-vih-en-mujeres-j%C3%A3-venes-chilenas-que-participaron-en-la-intervenci%C3%A3-n-online-i-stipi-factors-that-influence-the-acquisition-of-sexually-transmitted-infections-and-hiv-in-chilean
#20
Natalia Villegas, Rosina Cianelli, Daniel Santisteban, Loreto Lara, Jessica Vargas
The aim of this descriptive cross-sectional study was to investigate the following factors associated with sexually transmitted infections and human immunodeficiency virus prevention: (a) knowledge, (b) attitudes, (c) self-efficacy, (d) vulnerability, (e) risky behaviors, (f) preventive behaviors, and (g) internet use among 40 Chilean women between 18 and 24 years who participated in the pilot of an Internet based STI/HIV prevention intervention (I-STIPI). A structured questionnaire available in a secure website was used for data collection and it included questions related to STI and HIV prevention...
March 2016: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
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