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https://www.readbyqxmd.com/read/28807061/the-incidence-of-hyperthermia-during-cochlear-implant-surgery-in-children
#1
A Schwartz, D Kaplan, V Rosenzweig, M Klein, B F Gruenbaum, S E Gruenbaum, M Boyko, A Zlotnik, E Brotfain
BACKGROUND: Inadvertent hyperthermia during anaesthesia is a rare but life-threatening complication. We have encountered several cases of severe hyperthermia in paediatric patients undergoing anaesthesia for cochlear implantation. METHODS: This study aimed to describe the clinical characteristics of children who developed hyperthermia while undergoing cochlear implantation, and to explore possible mechanisms and predisposing factors. The anaesthetic charts of all patients aged under 18 years who underwent cochlear implantation, or mastoid or ophthalmic surgery, between 1 January 2006 and 31 December 2009, at Soroka Medical Center in Beer Sheva, Israel, were reviewed...
August 15, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28803710/intrathecal-2-hydroxypropyl-%C3%AE-cyclodextrin-decreases-neurological-disease-progression-in-niemann-pick-disease-type-c1-a-non-randomised-open-label-phase-1-2-trial
#2
Daniel S Ory, Elizabeth A Ottinger, Nicole Yanjanin Farhat, Kelly A King, Xuntian Jiang, Lisa Weissfeld, Elizabeth Berry-Kravis, Cristin D Davidson, Simona Bianconi, Lee Ann Keener, Ravichandran Rao, Ariane Soldatos, Rohini Sidhu, Kimberly A Walters, Xin Xu, Audrey Thurm, Beth Solomon, William J Pavan, Bernardus N Machielse, Mark Kao, Steven A Silber, John C McKew, Carmen C Brewer, Charles H Vite, Steven U Walkley, Christopher P Austin, Forbes D Porter
BACKGROUND: Niemann-Pick disease, type C1 (NPC1) is a lysosomal storage disorder characterised by progressive neurodegeneration. In preclinical testing, 2-hydroxypropyl-β-cyclodextrins (HPβCD) significantly delayed cerebellar Purkinje cell loss, slowed progression of neurological manifestations, and increased lifespan in mouse and cat models of NPC1. The aim of this study was to assess the safety and efficacy of lumbar intrathecal HPβCD. METHODS: In this open-label, dose-escalation phase 1-2a study, we gave monthly intrathecal HPβCD to participants with NPC1 with neurological manifestation at the National Institutes of Health (NIH), Bethesda, MD, USA...
August 10, 2017: Lancet
https://www.readbyqxmd.com/read/28802356/intracranial-complications-of-csom-in-pediatric-patients-a-persisting-problem-in-developing-countries
#3
Avani Jain, Nikhil Arora, Ravi Meher, J C Passey, Ramanuj Bansal
BACKGROUND: Intracranial complications (ICC) of chronic suppurative otitis media (CSOM) occur even in the antibiotic area. These complications are commonly seen in pediatric patients due to poor hygiene and low immunity. They are more prevalent in developing countries due to illiteracy, low socioeconomic status and lack of access to health care facilities. OBJECTIVE: To study the incidence, clinical profile, treatment and outcome of pediatric patients presenting with intracranial complications of chronic suppurative otitis media...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28801828/a%C3%A2-new-classification-system-is-helpful-in-diagnosing-intracranial-complications-of-acute-mastoiditis-in-ct
#4
R Saat, G Kurdo, N Brandstack, A Laulajainen-Hongisto, J Jero, A Markkola
PURPOSE: To assess the usefulness of the new computed tomography (CT) classification criteria proposed by Horowitz et al. and their effect on inter-observer agreement when estimating intracranial complications of acute mastoiditis. METHODS: In this study 53 contrast-enhanced CT scans of patients with acute mastoiditis were each retrospectively reviewed by two radiologists, using two different assessment criteria for intracranial complications. According to the new criteria, intracranial CT findings in the perisinuous area were graded into four classes (I normal, II linear halo, III nodular halo ≤4 mm thick and IV nodular halo >4 mm thick), where classes III and IV indicate a high risk for epidural abscesses...
August 11, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28798906/cerebral-sinovenous-thrombosis
#5
REVIEW
Rebecca Ichord
Cerebral sinovenous thrombosis (CSVT) is a rare but serious cerebrovascular disorder affecting children from the newborn period through childhood and adolescence. The incidence is estimated at 0.6/100,000/year, with 30-50% occurring in newborns. Causes are diverse and are highly age dependent. Acute systemic illness is the dominant risk factor among newborns. In childhood CSVT, acute infections of the head and neck such as mastoiditis are most common, followed by chronic underlying diseases such as nephrotic syndrome, cancer, and inflammatory bowel disease...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28798718/vestibular-modulation-of-sympathetic-nerve-activity-to-muscle-and-skin-in-humans
#6
REVIEW
Elie Hammam, Vaughan G Macefield
We review the existence of vestibulosympathetic reflexes in humans. While several methods to activate the human vestibular apparatus have been used, galvanic vestibular stimulation (GVS) is a means of selectively modulating vestibular afferent activity via electrodes over the mastoid processes, causing robust vestibular illusions of side-to-side movement. Sinusoidal GVS (sGVS) causes partial entrainment of sympathetic outflow to muscle and skin. Modulation of muscle sympathetic nerve activity (MSNA) from vestibular inputs competes with baroreceptor inputs, with stronger temporal coupling to the vestibular stimulus being observed at frequencies remote from the cardiac frequency; "super entrainment" was observed in some individuals...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28796089/anatomical-relationship-of-the-middle-cranial-fossa-dura-to-surface-landmarks-of-the-temporal-bone
#7
Mohamed A Alhussaini, Jameson K Mattingly, Stephen P Cass
HYPOTHESIS: The suprameatal crest and temporal line provides a reliable landmark to the middle fossa dura. BACKGROUND: Surface anatomy of the temporal bone is used to guide mastoid surgery, but studies investigating these landmarks are limited. The aim of this study was to examine the anatomical relationship of the middle fossa dura to the temporal line. METHODS: Thirty-two fresh hemicephalic temporal bones were prepared by drawing four lines along the mastoid including the suprameatal crest and temporal line (line 2), one line 5 mm superior to line 2 (line 1), and one 5 mm inferior to line 2 (line 3), and at Reid's base line (line 4)...
August 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28790965/heterogeneity-in-reported-outcome-measures-after-surgery-in-superior-canal-dehiscence-syndrome-a-systematic-literature-review
#8
REVIEW
Mira E Ossen, Robert Stokroos, Herman Kingma, Joost van Tongeren, Vincent Van Rompaey, Yasin Temel, Raymond van de Berg
BACKGROUND: Superior canal dehiscence syndrome (SCDS) can be treated surgically in patients with incapacitating symptoms. However, the ideal treatment has not been determined. OBJECTIVES: This systematic literature review aims to assess available evidence on the comparative effectiveness and risks of different surgical treatments regarding: (1) symptom improvement; (2) objectively measurable auditory and vestibular function; (3) adverse effects, and (4) length of hospitalization...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28790884/the-effect-of-electroencephalogram-eeg-reference-choice-on-information-theoretic-measures-of-the-complexity-and-integration-of-eeg-signals
#9
Logan T Trujillo, Candice T Stanfield, Ruben D Vela
Converging evidence suggests that human cognition and behavior emerge from functional brain networks interacting on local and global scales. We investigated two information-theoretic measures of functional brain segregation and integration-interaction complexity C I (X), and integration I(X)-as applied to electroencephalographic (EEG) signals and how these measures are affected by choice of EEG reference. CI(X) is a statistical measure of the system entropy accounted for by interactions among its elements, whereas I(X) indexes the overall deviation from statistical independence of the individual elements of a system...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28777229/the-modified-rambo-transcanal-approach-for-cochlear-implantation-in-charge-syndrome
#10
Cameron C Wick, Amy M Moore, Daniel E Killeen, Brandon Isaacson
OBJECTIVE: CHARGE syndrome is associated with a variety of temporal bone anomalies and deafness. The lack of surgical landmarks and facial nerve irregularities make cochlear implantation in this population a challenging endeavor. This study aims to describe a safe and efficacious transcanal approach for cochlear implantation that obviates the need to perform a mastoidectomy and facial recess. PATIENTS: Three children with profound hearing loss secondary to CHARGE syndrome...
August 2, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28774693/characterizing-the-skull-base-in-craniofacial-microsomia-using-principal-component-analysis
#11
S C Schaal, C Ruff, B I Pluijmers, E Pauws, C W N Looman, M J Koudstaal, D J Dunaway
The aim of this study was to compare the anatomical differences in the skull base between the affected and non-affected side in patients with craniofacial microsomia (CFM), and to compare the affected and non-affected sides with measurements from a normal population. Three-dimensional computed tomography scans of 13 patients with unilateral CFM and 19 normal patients (age range 7-12 years) were marked manually with reliable homologous landmarks. Principal component analysis (PCA), as part of a point distribution model (PDM), was used to analyse the variability within the normal and preoperative CFM patient groups...
July 31, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28764209/mastoid-osteoma-of-temporal-bone-a-rare-case-report
#12
Rahul Kumar Singh, Amit Goyal, Amit Kumar, Gaurav Kataria, Amber Kesarwani
Osteomas of the temporal bone are rare entity with incidence of 0.1% - 1% of all benign tumours of skull. They are slow growing benign lesion of temporal bone. We report a rare case of mastoid osteoma of size more than 5 cm. A 40-year-old female patient presented to us with left post auricular bony swelling of size greater than 5 cm. Diagnosis of mastoid osteoma was made after relevant investigations including High Resolution Computed Tomography (HRCT) temporal bone. Complete surgical excision was done with good cosmetic outcome without recurrence...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28756095/surgical-considerations-and-safety-of-cochlear-implantation-in-otitis-media-with-effusion
#13
Rasit Cevizci, Alper Dilci, Fatih Celenk, Recep Karamert, Yildirim Bayazit
OBJECTIVE: To evaluate the effects of otitis media with effusion on surgical parameters, patient safety, perioperative and postoperative complications. METHODS: Total 890 children who underwent cochlear implantation between 2006 and 2015 were included. The ages ranged from 12 months to 63 months (mean: 32 months). The patients were divided into two groups according to the presence or absence of otitis media with effusion; otitis media with effusion group and non-otitis media group...
July 26, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28742630/unique-case-of-hearing-recovery-after-otic-capsule-destruction-and-complete-sensorineural-hearing-loss-caused-by-langerhans-cell-histiocytosis
#14
Jennifer A Losie, Michael Yong, Frederick K Kozak, Neil K Chadha
: A 14-year-old woman presented with right-sided otologic and vestibular symptoms after presenting with hormonal disturbances earlier that year. Imaging showed a gross destruction of the temporal bone, mastoid air cells, and external acoustic meatus with invasion into the otic capsule. The patient experienced complete sensorineural hearing loss in the right ear. Biopsy diagnosed Langerhans cell histiocytosis (LCH) and the patient was treated with chemotherapy. After 1 year of treatment, the patient's hearing partially recovered and imaging showed reconstitution of the temporal bone including the otic capsule...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28738189/surgical-landmarks-to-locating-the-main-trunk-of-the-facial-nerve-in-parotid-surgery-a-systematic-review
#15
Yisi D Ji, R Bruce Donoff, Zachary S Peacock, Eric R Carlson
PURPOSE: The purpose of this study was to describe distances from commonly used anatomic landmarks to the main trunk of the facial nerve during parotid surgery. MATERIALS AND METHODS: A systematic search of the published literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All studies from January 1, 1990 to January 1, 2017 that measured distances to the main trunk of the facial nerve from common anatomic landmarks were eligible...
June 30, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28737551/vibrotactile-thresholds-on-the-mastoid-and-forehead-position-of-deaf-patients-using-radioear-b71-and-b81
#16
Karl-Johan Fredén Jansson, Bo Håkansson, Sabine Reinfeldt, Laura Fröhlich, Torsten Rahne
OBJECTIVES: The main objective of this study was to measure the vibrotactile thresholds on the mastoid process and forehead positions using patients with bilateral deafness and to compare the results from the two bone conduction vibrators Radioear B71 and B81. DESIGN: There is a possibility that the vibrotactile sensation on the skin makes it difficult to discriminate between sound and vibration. The risk is highest for patients who have bone conduction hearing thresholds in proximity to or worse than their vibrotactile thresholds...
July 21, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28736098/posterior-canal-wall-reposition-for-management-of-cholesteatoma-technique-and-results
#17
Mohammad Kamal Mobashir, Waleed M Basha, Abd ElRaof Said Mohamed, Mohammed Elsayed Elmaghawry
OBJECTIVE: The main goal of surgery in acquired middle ear cholesteatomas is the complete eradication of the disease with an ear free of discharge. This can be performed either by open or closed techniques with their benefits and drawbacks. We present the technique of reposition of the posterior canal wall for the management of cholesteatoma cases and its results and outcome. PATIENTS AND METHODS: This study included 31 patients with primary acquired middle ear cholesteatoma...
July 20, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28733757/the-clinico-radiological-spectrum-of-dyke-davidoff-masson-syndrome-in-adults
#18
Zeynep Özözen Ayas, Kıyasettin Asil, Ruhsen Öcal
Dyke-Davidoff-Masson syndrome (DDMS) is characterized by cerebral hemiatrophy, seizure, contralateral hemiplegia/hemiparesis, and mental retardation. In this study, clinical and radiological investigations of seven patients who were diagnosed with DDMS as adult age were evaluated and discussed. Seven patients (four male, three female) were included. The mean age ± SD of the patients was 46 ± 21 years. Clinical presentation of six patients was epileptic seizure. One patient was presented with head trauma due to a fall...
July 21, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28728320/temple-and-postauricular-dissection-in-face-and-neck-lift-surgery
#19
Joo Heon Lee, Tae Suk Oh, Sung Wan Park, Jae Hoon Kim, Tanvaa Tansatit
Periauricular paresthesia may afflict patients for a significant amount of time after facelift surgery. When performing face and neck lift surgery, temple and posterior auricular flap dissection is undertaken directly over the auriculotemporal, great auricular, and lesser occipital nerve territory, leading to potential damage to the nerve. The auriculotemporal nerve remains under the thin outer superficial fascia just below the subfollicular level in the prehelical area. To prevent damage to the auriculotemporal nerve and to protect the temporal hair follicle, the dissection plane should be kept just above the thin fascia covering the auriculotemporal nerve...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28726666/-pathomorphological-changes-under-latent-mastoiditis
#20
Kh Chitadze, T Jorbenadze, M Adamia
In our opinion it is caused by incomplete awareness of the distribution of pathological process and the character of morphological changes in the patients. In this regard, we studied structural changes in the soft and bone tissue taken from various cavities of the middle ear system. Operating material was formed in paraffin after the fixation and proper processing. We proceed with decalcification of bone tissues in 15-20% nitric acid. We painted 5-6 mm thick peels prepared on the rotating microtome with hematoxylin and eosin...
June 2017: Georgian Medical News
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